South East European Journal of Cardiology
Published by: Macedonian Journal of Medical Sciences
Total articles ≅ 4
Articles in this journal
Published: 10 October 2021
South East European Journal of Cardiology, Volume 2, pp 12-14; https://doi.org/10.3889/seejca.2021.6030
BACKGROUND: Ventricular tachyarrhythmias as complication of LV aneurysm are not unusual complication and can lead to sudden cardiac death. The accepted consensus for treatment of LV aneurism is medical therapy unless other indication for surgery exists, or existing treatment cannot control the symptoms. CASE REPORT: A 29-year-old man with no prior cardiac history was admitted to the hospital, after an episode of chest pain accompanied with fatigue and dizziness, for the last 2 h. His electrocardiogram on admission showed ventricular tachycardia with heart rate 260/min. Selective coronarography was performed and no significant stenosis of coronary artery was found. On transthoracic echocardiography, the left ventricle was mildly dilated (ejection fraction 50%), but whole apex was akinetic with giant aneurism. CONCLUSION: Aneurysms of the LV, sometimes associated with malignant ventricular arrhythmias, are very late complication of myocardial infarction. Resection of the aneurysm, although has no high-class recommendation (2), can cure the ventricular arrhythmias, as in presented case.
Published: 10 October 2021
South East European Journal of Cardiology, Volume 2, pp 7-11; https://doi.org/10.3889/seejca.2021.6026
BACKGROUND: Transradial access is currently the default access site for percutaneous cardiovascular interventions. Radial artery (RA) anomalies present a significant challenge in radial access success. RA 360-degree loops are an uncommon, but quite challenging vascular anomaly even for the most experienced radial operators. CASE REPORT: We report on two cases of patients with complex RA loops referred for PCI through radial approach in a high-volume radial center. Pre-procedural RA angiography was performed in both cases identifying a 360-degree RA loop in the proximal part of the RA below the entrance into the brachial artery. In both cases, we present a novel “Microcatheter crossing” technique of the complex RA loop as a new strategy in overcoming even the most difficult radial adversary. After identifying the loop a hydrophilic wire 0.014 inch was used to cross the loop and extend it in the upper arm. Then a microcatheter ASAHI corsair (Asahi Intecc USA, Inc.) was advanced through the loop without difficulty. The microcatheter is advanced through the wire until middle of the upper arm. Hydrophilic wire is then exchanged with High Torque Iron man guide wire (Abbott Vascular). Again, the wire is advanced in the upper arm. Microcatheter is then removed and 5F catheter JR 4.0 or similar is advanced gently through the iron man wire with a clockwise rotation through the loop. Then, wire and catheter are pulled back to straighten the loop. The percutaneous angiography procedure was performed successfully in both cases. CONCLUSION: Both patients were discharged without registered bleeding complications from place of puncture. They both reported slight pain during the beginning of the procedure in the arm of puncture, but without additional problems after the procedure.
Published: 10 October 2021
South East European Journal of Cardiology, Volume 2, pp 1-6; https://doi.org/10.3889/seejca.2021.6025
INTRODUCTION: Post-operative atrial fibrillation (POAF) is a frequent rhythmic complication in cardiac surgery with the potential to cause sudden hemodynamic instability and catastrophic thromboembolic complications. Despite vast scientific research, it is still hard to predict and prevents its occurrence. AIM: The aim of this study was to determine whether selected pre-operative and intraoperative echocardiographic variables would be of added value in POAF prediction. МАTERIAL AND METHODS: This prospective observational follow-up study included 178 cardiac surgery patients undergoing coronary artery bypass graft intervention. Demographic as well as echocardiographic variables of interest were examined to detect significant independent predictors for POAF. RESULTS: POAF was detected in 90 (50.56%) patients versus 88 (49.44%) patients without POAF. Patients who developed POAF were significantly older and burdened with multiple comorbidities. In multiple regression analysis pre-operative echocardiographic variables-diastolic dysfunctions, enlarged left atrial (LA) volume indexed for body surface area, mitral annular calcification, and secondary mitral regurgitation were predictive of POAF. LA appendage flow velocity obtained by intraoperative transesophageal echocardiography was also a significant intraoperative predictor for POAF. CONCLUSION: The results of this study confirmed that two-dimensional echocardiography is a valuable diagnostic and prognostic tool in relation to POAF. The addition of the aforementioned echocardiographic independent predictors to traditional demographic variables could be a solid foundation of a new predictive model for POAF.
Published: 21 August 2015
South East European Journal of Cardiology, Volume 2015; https://doi.org/10.3889/seejca.2015.30001
AIM: The aim was to analyze association of Factor V Leiden (G1691A), Factor V R2 (A4070G) , and Prothrombin (G20210A) Genetic Polymorphism in Macedonian Patients with Occlusive Artery Disease (OAD) and Deep Vein Thrombosis (DVT). METHODS: Investigated groups consists of 82 healthy, 76 patients with OAD, and 67 patients with DVT. Blood samples were collected after written consent, and DNA was isolated from peripheral blood leukocytes. Identification of Factor V Leiden (G1691A), Factor V R2 (A4070G) , and Prothrombin (G20210A) Genetic Polymorphism was done with CVD StripAssay (ViennaLab, Labordiagnostica GmbH, Austria). The population genetics analysis package, PyPop, was used for analysis of the data. Pearson's P -values, crude Odds Ratio and Wald’s 95% CI were calculated. RESULTS: The frequency of G allele for Factor V Leiden was 0.976 for healthy participants, 0.954 for OAD, and 0.948 for DVT. The frequency of A allele for Factor R2 is highest in healthy participants (0.951), smaller in patients with DVT (0.918), and smallest in the patients with OAD (0.908). G allele frequency for prothrombin was 0.976 in healthy participants, 0.980 in patients with OAD, and 0.978 in patients with DVT. Test of neutrality (Fnd) showed positive value, but was not significantly different from 0. Factor V Leiden (G1691A), Factor R2 (A4070G) , and Prothrombin (G20210A) genotypes in healthy participants and patients with OAD and DVT were in Hardy Weinberg proportions. Any association of Factor V Leiden (G1691A), Factor R2 (A4070G) , and Prothrombin (G20210A) genetic polymorphism with OAD, and DVT in Macedonians was not found. CONCLUSION: We conclude that significant association of Factor V Leiden (G1691A), Factor R2 (A4070G), and Prothrombin (G20210A) genetic polymorphism with occlusive artery disease or deep venous thrombosis in Macedonians was not found.