European Journal of Chemistry

Journal Information
ISSN / EISSN: 21532249 / 21532257
Total articles ≅ 1,040

Latest articles in this journal

Published: 30 September 2022
European Journal of Chemistry, Volume 13, pp 253-258; https://doi.org/10.5155/eurjchem.13.3.253-258.2235

Abstract:
N'-Acetyl-N'-phenyl-2-naphthohydrazide, a biologically relevant organic molecule, was synthesized following a reported method and characterized based on its single X-ray crystallographic studies. The present manuscript deals with its detailed molecular interactions and X-ray crystal structure. Its space group is P-1 with the following unit cell parameters: a = 8.9164(7), b = 9.7058(9), c = 17.7384(12) Å, α = 88.308(7)°, β = 89.744(6)°, γ = 86.744(7)° and Z = 2. Crystal structure was solved by direct method and refined by full matrix least squares procedure to a final R value of 0.0580 and to a GOOF value of 1.066. The X-ray diffraction analyses showed that the asymmetric unit contains two crystallographically independent molecules. The crystal structure is stabilized by elaborate network of N-H···O and C-H···O hydrogen bonds along with C-H···π and π···π interactions to form supramolecular structures.
Published: 30 September 2022
European Journal of Chemistry, Volume 13, pp 337-350; https://doi.org/10.5155/eurjchem.13.3.337-350.2297

Abstract:
A detailed study of the electronic band structures and partial density of states of Bi5O7NO3 with different exchange correlation functionals was performed using the generalized gradient approximation. Bi5O7NO3 has two direct energy gap transitions of 2.84 and 3.66 eV at the experimental lattice parameters, revealing a semiconductor characteristic of a crystal. Molecular Mechanics; however, tends to underestimate the band-gap energies with indirect characters. This deviation is due to the slight decrease in the cell edges and the significant increase in the β angle during the optimization process. The mechanism of removal of methyl orange and its derivatives by the Bi5O7NO3 unit cell, which has the same experimental UV-Vis band gap, was later investigated through a DMol3 module. To do that, frontier molecular orbitals, global reactivity parameters, and electrostatic potential surface maps were evaluated. The high values of the electrophilicity indexes hint that the dyes are more reactive and can work as good electrophile species. A molecular packing of dye molecules and the ionic natural of Bi5O7NO3 generate a synergistic effect between π-π stacking, anion-π stacking, cation-π stacking and electrostatic interactions, which are thought to be the driven forces during dye removal.
Published: 30 September 2022
European Journal of Chemistry, Volume 13, pp 299-306; https://doi.org/10.5155/eurjchem.13.3.299-306.2280

Abstract:
Ni(II), Cu(II), and Zn(II) complexes of the tridentate heterocyclic ligand, 2-(phenyl(pyridin-2-yl)methylene)hydrazine-1-carbothioamide (HL) have been synthesized and characterized by various spectroscopic techniques and elemental analyses. Infrared spectroscopy shows that the ligand coordinates to the metal ions through the azomethine and pyridine nitrogen atoms as well as the sulfur atom of the thioamide group to form a tridentate chelate system. In vitro screening of metal complexes against four bacterial strains (Staphylococcus aureus (ATCC 43300), Klebsiella pneumoniae (ATCC 700603), Methicillin resistant staphylococcus aureus (ATCC 33591), Shigella flexneri (NR 518)) and four fungal strains (Candida albicans (NR 29444), Candida albicans (NR 29445), Candida albicans (NR 29451), Candida krusei (HM 1122)) indicate that the Cu(II) complex showed good antibacterial activity on Methicillin resistant staphylococcus aureus (ATCC 33591)while the Zn(II) complex showed moderate activity against some of the bacterial and fungi strains. Antioxidant studies reveal that the complexes are more potent than the ligand to eliminate free radicals, with the Ni(II) complex showing the best free radical scavenger.
Published: 30 September 2022
European Journal of Chemistry, Volume 13, pp 327-336; https://doi.org/10.5155/eurjchem.13.3.327-336.2295

Abstract:
The study seeks to determine the most significant factors affecting arsenic and chromium enrichment using novel P-ZrO2CeO2ZnO nanoparticles/alginate beads in order to minimize the total number of runs needed to successfully run the experiment. The effects of interactions between factors were also evaluated so that the optimum conditions which are not affected by the other factors are chosen for the experiments. The most significant factors on arsenic and chromium enrichment were screened for by using a half-factorial design, followed by the optimization of significant factors using the full-factorial design, and the interaction between factors was determined using ANOVA and interaction plots. The most significant factors for chromium recovery were sample volume, eluent flow rate, and sorbent dosage. For both chromium and arsenic recovery, interactions occurred between sample volume, dosage, and pH. The optimum conditions chosen for the experiment that gave favourable results for both metal ions were sample volume 5 mL, dosage 40 mg, pH = 7 and eluent flow rate 1 mL/min. This study showed that a preliminary screening step for the most significant factors for arsenic and chromium enrichment helps to reduce the number of total runs, and for the same experiment interactions between factors were present; hence, it is necessary to take this into account during the experimental design.
Published: 30 September 2022
European Journal of Chemistry, Volume 13, pp 351-357; https://doi.org/10.5155/eurjchem.13.3.351-357.2310

Abstract:
A new hydrazide functionalized Schiff’s base derivative, N'-(3,4-dichlorobenzylidene)-4-hydroxybenzohydrazide (I), has been synthesized using a solvent-assisted mechano-chemical grinding strategy and structurally characterized using elemental analysis, 1H NMR and crystallographic studies. The single crystal X-ray diffraction study depicts that molecule is puckered with two aromatic rings lying out-of-plane in near anti-configuration across the C=N bond. The weak interactions involved in supramolecular framework formation are Cl···O, Cl···Cl, Cl···H, Cl···N, C···H, and O···H contacts. The intermolecular O···H interaction being stronger than other dispersive interactions such as halogen bonding, interlocks the molecules in a 2D sheet-type packing. All the structure directing interactions involved in developing crystal architecture are addressed with Hirshfeld surface analysis and fingerprint plots. The energy framework analysis shows visualization of 3D topology of short contacts related to molecular packing of compound I which further clarifies the predominance of both Coulombic and dispersive energies in developing supramolecular architecture.
Published: 30 September 2022
European Journal of Chemistry, Volume 13, pp 307-318; https://doi.org/10.5155/eurjchem.13.3.307-318.2282

Abstract:
Inducible nitric oxide synthase (iNOS) plays an important role in the inflammatory processes via accelerating the production of nitric oxide (NO). The efforts to develop small molecules as selective inhibitors of iNOS are being reported across the globe. The current study explores varied benzimidazole-coumarin derivatives as anti-iNOS agents. Literature survey suggests 2-aminobenzimidazole, coumarin nucleus, and 4-atom linker as important structural components for iNOS inhibition. Target compounds were designed and synthesized by coupling 2-aminobenzimidazole with (un)substituted coumarin through different linkers. These were docked in iNOS (1QW4) and nNOS (1QW6) targets to ascertain their iNOS selectivity, and evaluated for NO and iNOS inhibitory activities in vitro. The most active inhibitors were subsequently evaluated for acute toxicity and anti-inflammatory activity using carrageenan-induced rat paw edema model in vivo. All compounds possessed moderate to good NO and iNOS inhibitory activities. Compounds 14a, 14b, 14d, and 14e were the most potent inhibitors in vitro. These were found to significantly reduce the inflammation. Compounds 14d and 14e have been identified as the most potent iNOS inhibitors to combat inflammation. These derivatives may serve as potential compounds as such against iNOS, or as leads for the development of novel anti-iNOS agents.
Published: 30 September 2022
European Journal of Chemistry, Volume 13, pp 358-368; https://doi.org/10.5155/eurjchem.13.3.358-368.2251

Abstract:
Graphene is showing its versatility continuously by playing the most important role in many fields of science. Water treatment is one of them. In the present scenario, the supply of the safe and pure water has become the main priority. Especially, the most denser and populated areas are demanding of it. Although water treatment is done by applying different methods using different materials, no material showed the results as good as graphene-based materials. The current article deliberates not only the main properties of graphene but also their importance in the treatment of water. Besides, the current review also pronounces the method of graphene separation from the water after use and recycling. Efforts are made to discuss the role of graphene materials in the treatment of water. Henceforward, this article will definitely be very helpful for researchers, academicians, and administration authorities who are planning and developing new strategies for the removal of ionic as well as organic impurities from water.
Published: 30 September 2022
European Journal of Chemistry, Volume 13, pp 273-278; https://doi.org/10.5155/eurjchem.13.3.273-278.2273

Abstract:
The extraction behaviour of zirconium(IV) from sulfuric acid medium has been studied with a binary mixture of tri-n-octyl amine (TOA) and Cyanex923 (a mixture of four trialkyl phosphine oxides) in kerosene using a novel liquid-liquid extraction method. Quantitative extraction of zirconium(IV) with binary mixture of Cyanex923 and TOA in kerosene was studied by changing different parameters such as acid variation, extractant variation, effect of chloride ion concentration, effect of temperature, metal concentration variation, diluent effect, and pH effect. The percentage of extraction of zirconium(IV) decreased when the concentration of Cyanex923 and TOA increased. The percentage of zirconium(IV) was observed as 97.56% in a binary mixture of 0.007 M Cyanex923 and 0.06 M TOA. Kerosene was found to be an effective diluent for the extraction of zirconium(IV) with 97.56% extraction using a binary mixture of Cyanex923 and TOA. In addition, the stripping of the zirconium(IV) metal ion in the organic phase was also examined.
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