Journal of Biology and Medicine

Journal Information
EISSN: 26888408
Total articles ≅ 19

Latest articles in this journal

Jia Li, Zhu Xianglei, Xu Guoliang
Journal of Biology and Medicine, Volume 6, pp 042-047;

Based on the visualization analysis of foreign literature on altruistic behavior in recent ten years (2012-2022) by CiteSpace, it is found that the research on altruistic behavior in the field of biology abroad has experienced the initial exploratory stage, the outbreak stage, and now enters the stable and deepening stage. The discipline distribution is mainly behavioral ecology, supplemented by evolutionary biology, biomathematics, and genetics. The author has three main cooperative groups, and a relatively tight cooperative network has been formed locally in related fields. From the perspective of cooperation degree, the cooperation density of major research institutions is high, and relevant research has been relatively mature. Judging from the period calculated in the software, altruism, cooperation, kin Selection, reciprocity, and inclusive fitness emerged earlier. In recent years, constitutive theory, density dependence, and Habitat construction have emerged, which may become a new direction for future research. Therefore, future research can expand the scope of disciplines, strengthen the cooperation between authors and units, and explore other research hotspots.
Ford Brian J
Journal of Biology and Medicine, Volume 6, pp 029-041;

The many legacies bequeathed to us by the COVID-19 pandemic have embraced novel approaches to vaccine development, a greater awareness of the principles of hygiene among the general public, the need for governments to take a proactive stance when faced with unfamiliar pathologies, and the role of specialist medical and scientific advisers. However, many of the claimed protocols are medieval in nature and have little scientific evidence to support their introduction. Similarly, we have failed to grasp the importance of the anti-vaccination campaigns, which are always founded on ignorance or willfulness, but on previous examples of duplicitous behavior by those in authority, coupled with our poor understanding of the way virus variants function, have engendered a sense that many of the precautions taken may have been unnecessary (Ford, 2020a). In consequence, I fear that future threats from hemolytic viruses of high transmissibility may be met with complacency. Improved public education, and greater academic transparency concerning the nature of risk, will be necessary if a future pandemic is to be effectively controlled.
Pe Ngwu, Ie Ihedoro, Ei Kalu
Journal of Biology and Medicine, Volume 6, pp 024-028;

Introduction/Background: Benign Prostatic Hyperplasia (BPH) is characterized by narrowing of the prostatic urethra with resultant difficulty in passing urine, stasis, and a predisposition to urinary tract infection. The objective of this study is to identify the prevalence of urinary tract infections, common organisms isolated, their antimicrobial sensitivity pattern, and the relationship of co-morbidities with urinary tract infection in this population. Materials and methods: All patients who presented to our urology team with bladder outlet obstruction secondary to benign prostatic hyperplasia between January 2020 and January 2021 were included. Information on age, occupation, co-morbid conditions, urine microscopy, culture, and sensitivity patterns were obtained and analyzed using SPSS version 25. Midstream urine samples were collected from 172 BPH patients. Microscopy, culture, and antibiotic susceptibility tests were carried out. Results: From our study, the prevalence of bacteriuria was 67.9% with the 65-74 and 45-54 age groups having the highest and the least prevalence of bacteriuria (88.9% and 33.3% respectively). The most common organisms cultured from their urine were Pseudomonas (17.9%), E. coli (14.3%), Coliforms (10.7%), and Klebsiella (10.7%). Sensitivity patterns of these microorganisms revealed the highest sensitivity to the fluoroquinolones (25.9%) followed by Nitrofurantoin (14.8%) and Ceftriaxone and Cefoxitin (7.4%). The least sensitivity was to Augmentin and Gentamycin. Conclusion: Bacteriuria is common in patients with BPH. Pseudomonas spp was the commonest isolated organism in our study and most isolated organisms were susceptible to the fluoroquinolones.
J Topinka, P Rossner, A Rossnerova, Rj Sram
Journal of Biology and Medicine, Volume 6, pp 021-023;

A review of recent literature indicates a significant effect of air pollution on the increased incidence of dementia, particularly Alzheimer’s disease. A possible mechanism is related to oxidative damage and inflammation. In the Czech Republic in previous decades the mining districts of Northern Bohemia suffered from very high air pollution levels, while during the last period in Northern Moravia this problem was also noted. This specific situation could be used to study the impact of air pollution on dementia, using new methods of molecular epidemiology together with the complex analysis of the lifestyle of the population living in the polluted regions.
Protzman Nicole M, Mao Yong, Sivalenka Raja, Long Desiree, Gosiewska Anna, Hariri Robert J, Brigido Stephen A
Journal of Biology and Medicine, Volume 6, pp 010-020;

Tendon injuries are associated with considerable pain and disability. Owing to the hypovascularity and hypocellularity of the tissue, natural tendon healing is slow and ineffective. Traditional conservative and surgical treatment options fail to address the underlying pathology. As a result, the healed tendon is mechanically incompetent and prone to degeneration and rupture. Therefore, new biological methods have been suggested to enhance tendon repair and regeneration. Flowable Placental Connective Tissue Matrices (FP-CTMs) represent a promising means to promote tendon healing. Like non-flowable placental scaffolds, FP-CTMs possess the innate healing properties of the placenta and provide structural and biochemical extracellular matrix components. Unlike their non-flowable counterparts, FP-CTMs have the added benefits of minimal invasiveness and the capacity to fill irregular spaces. FP-CTMs can enhance tendon repair by providing a three-dimensional extracellular matrix for cellular attachment and proliferation while decreasing inflammation and limiting adhesion formation. The present report reviews tendon biology, pathology, healing, and current treatment modalities, followed by a comprehensive literature review, evaluating the clinical application of FP-CTMs for tendon repair. Recent research suggests that the use of FP-CTMs in tendon repair is safe and efficacious and further indicates that FP-CTMs can modulate the tendon repair environment and improve clinical outcomes. However, the existing clinical evidence is limited to retrospective case series with no control group. Therefore, additional work must be performed to better understand the clinical applications and therapeutic benefits of FP-CTM in tendon repair compared with conventional treatments.
Igwe Monday Nwite, Olose Emmanuel Omamurhomu, Obayi Okwudili, Igwe Chinonyerem, Ude Ugomma A, Ossai Edmund Ndudi
Journal of Biology and Medicine, Volume 6, pp 005-009;

Introduction: Autism is a neurodevelopmental disorder characterised by difficulties in social communication and interaction, repetitive patterns of behaviour and focused interests and activities. Medical social workers and Clinical psychologists play vital roles in identifying and supporting autistic children with their families. They may help with therapy, rehabilitation, crisis interventions and outreach services. Adequate knowledge about Autism Spectrum Disorders (ASD) among Medical social workers and Clinical psychologists may enhance early recognition, diagnosis, appropriate referral and interventions that are known to improve prognosis in autistic children. This study determined Medical social workers’ and Clinical psychologists’ understanding of ASD. Materials and methods: Socio-demographic and Knowledge About Childhood Autism among Health Workers (KCAHW) questionnaires were administered to consenting 63 Medical social workers and 35 Clinical psychologists. Results: Sixty-three Medical Social workers and 35 Clinical psychologists participated in the study. The mean age of Medical social workers was 42.1 ± 8.6 years and 41.0 ± 8.9 years for Clinical psychologists (P = 0.525). Clinical psychologists who were males were 42.9% and 41.3% were male Medical social workers (P = 0.879). Medical social workers who have ever managed a child with autism in the course of their career were 42.9% while Clinical psychologists were 40.0% (P = 0.784). The mean knowledge score for variables in domain 1 for Clinical psychologists was 6.34 ± 1.78 while Medical social workers scored 5.40 ± 2.30 (P = 0.038). The score in domain 2 for Clinical psychologists was 0.91 ± 0.28 while Medical social workers scored 0.71 ± 0.46 (P = 0.009). The mean total score for Clinical psychologists was13.00 ± 2.86 whereas Medical social workers scored 11.51 ± 3.43 (P = 0.031). Conclusion: Clinical psychologists significantly scored higher than Medical social workers in knowledge mean scores in domains 1 and 2 and total mean scores. The scores of Clinical Psychologists though higher than scores by Medical social workers are still considered inadequate. It is recommended that the training curriculum of Medical social workers and Clinical psychologists should involve more tutorials, teachings and clinical rotations that would expose them to different aspects of ASD.
Yang Iris
Journal of Biology and Medicine, Volume 6, pp 001-004;

Currently, the most common treatment options for pancreatic cancer include chemotherapy, radiation, and surgery. These treatment options are not specific to the cause of the disease and therefore result in a large number of side effects including nausea, fatigue, hair loss, etc. The use of oligonucleotides may be a more efficient and safe method of cancer therapy. This mini-review will cover how oligonucleotides have been used to treat diseases in the past as well as different methods for delivery into the body and finally the applications of oligonucleotides in pancreatic cancer therapy.
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