Environmental Science and Pollution Research

Journal Information
ISSN / EISSN: 09441344 / 16147499
Published by: Springer Nature
Total articles ≅ 35,438

Latest articles in this journal

Hua Huang, Xin Tao, , Xiaoqian Qin, Jialu Ren, Baoqin Shan, Yu Liu, Jingyu Ren
Published: 3 December 2022
Environmental Science and Pollution Research pp 1-13; https://doi.org/10.1007/s11356-022-24479-3

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Junying Wang, Wen Cao, Wenwen Wei,
Published: 3 December 2022
Environmental Science and Pollution Research pp 1-12; https://doi.org/10.1007/s11356-022-24313-w

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, , Abolfazl Askari Sari, Rashid Alijani Ardeshir, Mohammad Hossein Gorjian Arabi, Hamed Manouchehri
Published: 3 December 2022
Environmental Science and Pollution Research pp 1-9; https://doi.org/10.1007/s11356-022-24043-z

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Božena Skoko, Milica Kovačić, , Ankica Sekovanić, Jelena Kovačić, Agnieszka Sergiel, Tomasz Zwijacz-Kozica, Slaven Reljić, Branko Petrinec, Nuria Selva, et al.
Published: 3 December 2022
Environmental Science and Pollution Research pp 1-16; https://doi.org/10.1007/s11356-022-24397-4

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Yizhi Cheng, Xuan Bu, Jing Li, Zhihui Ji, Chenggang Wang, Xiao Xiao, Fenglin Li, Zhuo-Hui Wu, Guanxiong Wu, , et al.
Published: 3 December 2022
Environmental Science and Pollution Research pp 1-11; https://doi.org/10.1007/s11356-022-24488-2

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Jiangqin Chao, , Zhibin Lai, Shiguang Xu, Jianyu Liu, Ziyang Li, Xinle Zhang, Qi Chen, Haiying Yang, Xin Zhao
Published: 3 December 2022
Environmental Science and Pollution Research pp 1-18; https://doi.org/10.1007/s11356-022-24417-3

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Sylvia Gong, Flannery McLamb, Damian Shea, Jeanne P. Vu, Miguel F. Vasquez, Zuying Feng, Kesten Bozinovic, Ken K. Hirata, Richard M. Gersberg,
Published: 3 December 2022
Environmental Science and Pollution Research pp 1-17; https://doi.org/10.1007/s11356-022-24542-z

Abstract:
: Hexafluoropropylene oxide-dimer acid (HFPO-DA) is one of the emerging replacements for the “forever” carcinogenic and toxic long-chain PFAS. HFPO-DA is a polymerization aid used for manufacturing fluoropolymers, whose global distribution and undetermined toxic properties are a concern regarding human and ecological health. To assess embryotoxic potential, zebrafish embryos were exposed to HFPO-DA at concentrations of 0.5–20,000 mg/L at 24-, 48-, and 72-h post-fertilization (hpf). Heart rate increased significantly in embryos exposed to 2 mg/L and 10 mg/L HFPO-DA across all time points. Spinal deformities and edema phenotypes were evident among embryos exposed to 1000–16,000 mg/L HFPO-DA at 72 hpf. A median lethal concentration (LC50) was derived as 7651 mg/L at 72 hpf. Shallow RNA sequencing analysis of 9465 transcripts identified 38 consistently differentially expressed genes at 0.5 mg/L, 1 mg/L, 2 mg/L, and 10 mg/L HFPO-DA exposures. Notably, seven downregulated genes were associated with visual response, and seven upregulated genes were expressed in or regulated the cardiovascular system. This study identifies biological targets and molecular pathways affected during animal development by an emerging, potentially problematic, and ubiquitous industrial chemical.
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