Journal of Gynecological Research and Obstetrics

Journal Information
EISSN: 25815288
Total articles ≅ 116

Latest articles in this journal

Torres Gómez Francisco Javier, de Medina González Rosa Sánchez, Bravo Zambrano Beatriz, Bravo Vanesa Ortega
Journal of Gynecological Research and Obstetrics, Volume 8, pp 046-047; https://doi.org/10.17352/jgro.000116

Abstract:
As pathologists, cytotechnologists, and professors of pathology and cytology, we find ourselves disconcerted because we turn, in disbelief, to an unprecedented situation that could affect patient care and we refer to the exact opposite of that which could be considered in any medical treatise or scientific article from the 20th century.
, Şerbetçioğlu Gonca Çoban, Durdağ Gülşen Doğan, Baran Şafak Yılmaz, Aydın Şirin, Çelik Hüsnü
Journal of Gynecological Research and Obstetrics, Volume 8, pp 048-053; https://doi.org/10.17352/jgro.000117

Abstract:
Background: The purpose of this study is to investigate the effect of an adsorbent-antioxidant vaginal gel, which contains micronized silicon dioxide and antioxidant deflamin, on high-risk human papillomavirus (hr-HPV) clearance within the follow-up periods specified in the guidelines. Methods: In the study, the data of 52 patients infected with hr-HPV using vaginal gel for 3 months and 115 patients who were not using vaginal gel were analyzed retrospectively. Demographic characteristics, Liquid-Based Cytology (LBC) at the time of presentation, colposcopy findings, and cervical biopsy results of both groups were investigated. After the LBC and hr-HPV results were evaluated at the end of the control period, both groups were compared in terms of hr-HPV clearance. The level of statistical significance was taken as 0.05 in all tests. Results: The two groups had similar demographic data, cytological findings, colposcopy findings, and cervical biopsy results (p > 0.05). During similar follow-up periods (13.6 ± 3.2 vs. 14.1 ± 3.4 months; p > 0.05), there was no significant difference in terms of hr-HPV clearance (46.2% vs. 51.3%; p > 0.05). Furthermore, the initial and follow-up cytology results of the patients were similar (p > 0.05). Conclusions: A significant effect of the absorbent antioxidant vaginal gel on hr-HPV clearance at approximately 1-year follow-up could not be demonstrated.Background: The purpose of this study is to investigate the effect of an adsorbent-antioxidant vaginal gel, which contains micronized silicon dioxide and antioxidant deflamin, on high-risk human papillomavirus (hr-HPV) clearance within the follow-up periods specified in the guidelines. Methods: In the study, the data of 52 patients infected with hr-HPV using vaginal gel for 3 months and 115 patients who were not using vaginal gel were analyzed retrospectively. Demographic characteristics, Liquid-Based Cytology (LBC) at the time of presentation, colposcopy findings, and cervical biopsy results of both groups were investigated. After the LBC and hr-HPV results were evaluated at the end of the control period, both groups were compared in terms of hr-HPV clearance. The level of statistical significance was taken as 0.05 in all tests. Results: The two groups had similar demographic data, cytological findings, colposcopy findings, and cervical biopsy results (p > 0.05). During similar follow-up periods (13.6 ± 3.2 vs. 14.1 ± 3.4 months; p > 0.05), there was no significant difference in terms of hr-HPV clearance (46.2% vs. 51.3%; p > 0.05). Furthermore, the initial and follow-up cytology results of the patients were similar (p > 0.05). Conclusions: A significant effect of the absorbent antioxidant vaginal gel on hr-HPV clearance at approximately 1-year follow-up could not be demonstrated.
, Compagnie Sandrine, Allimonnier Laurine, Bracconi Manon, Giuliano Francois, Behr-Roussel Delphine
Journal of Gynecological Research and Obstetrics, Volume 8, pp 036-042; https://doi.org/10.17352/jgro.000114

Abstract:
Objectives: Endometriosis is a common disease that affects about 10% - 15% of women in their reproductive years worldwide with no curative treatment. The most common symptom of endometriosis is debilitating pelvic/abdominal pain. Current therapeutic options have limited insight into the disease mechanism and include drugs and/or surgery, which may be ineffective over the long term with unwanted side effects. We aimed at establishing a translational rodent endometriosis model that can be used to identify novel therapies. The validity of the model was confirmed by investigating the effect of the clinically-used GnRH agonist, leuprolide. Methods: Endometriosis was induced by a surgical procedure in adult non-pregnant female Sprague Dawley rats in the diestrus or estrus stage (cycle determination by vaginal smear). One group of rats received a subcutaneous injection of leuprolide at 1mg/kg, every 4 weeks. Following the treatment period, we performed a direct assessment of the endometriosis-induced abdominal pain using the Von-Frey method and spontaneous pain using the abdominal licking test. Then, the lesions were excised and measured. Results: Abdominal pain threshold was decreased by more than 2 fold in rats with surgically-induced endometriosis compared to sham rats. Leuprolide treatment significantly increased the threshold force required to elicit a behavioral withdrawal response in rats suffering from endometriosis. The observed pelvic floor mechanical hyperalgesia has not been correlated to the growth of endometriosis lesions. The hormonal cycle at the surgery induction influenced the endometriosis lesions growth. Leuprolide significantly inhibited the growth of endometriosis-like lesions. Conclusions: we have established, based on previously reported rodent models, a model of endometriosis-associated pain that responds to clinically active drugs and can, therefore, be used to identify novel therapies and investigate some of the pathophysiological mechanisms involved in endometriosis.
Rafael Zion Ben, David Mordechai Ben
Journal of Gynecological Research and Obstetrics, Volume 8, pp 031-035; https://doi.org/10.17352/jgro.000113

Abstract:
Assisted Zona Hatching (AZH) like most add-ons was introduced to In Vitro Fertilization and Embryo transfer (IVF/ET) in the early 1990s, when the live birth rate (LBR) in older women, age 35-39, was only 6%.
Hartmann Beda, Rindler Lisa, Hoenigschnabl Selma
Journal of Gynecological Research and Obstetrics, Volume 8, pp 022-024; https://doi.org/10.17352/jgro.000110

Abstract:
Background: The effects of Coronavirus disease 2019 in women during the second trimester of pregnancy and the health of the fetus, remain very poorly explored. This report describes a case in which the normal development of pregnancy was complicated immediately after the patient had experienced COVID-19 at the 21st week of gestation. Specific conditions included critical blood flow in the fetal umbilical artery, fetal growth restriction and hydramnios in the 25th week of gestation. After informed consent, we decided just to wait and interrupted all examinations (CTG, Ultrasound) because of the high risk of severe adverse events at such an early premature birth. The patient finally delivered a healthy boy in the 39th week of gestation. Methods: We performed a histological examination of the placenta and analyzed the placenta for the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) through molecular and immunohistochemical assays and measured the fetal antibody response in the blood to this infection. Results: In the immunohistochemical examination with antibodies against SARS-CoV-2 a partial positivity in the villious throphoblastic epithel cells could be demonstrated. The PCR swab of the placenta which was obtained was positive for SARS-CoV-2 with a crossing threshold value of 22,8. The histological examination of the placenta showed a Massive Perivillous Fibrinoid Deposition (MPFD) with multiple focal placental infarctions in the intervillious space, intervillious thrombus, and a localized chorangiomatosis. Conclusion: According to many clinical and laboratory findings in this patient, the histopathological features and viral infection of the placenta suggest a prominent role for COVID-19 in this patient’s presentation. This is highlighted by the presence of levels of SARS-CoV-2 RNA. In this patient, an infection with Sars-CoV-2 might have caused the development of the MPFD. These findings suggest that COVID-19 may have contributed to placental dysfunction and fetal growth retardation. Also with a SARS-CoV-2 PCR test with a crossing threshold value of 22,8, it must be assumed that the placenta has been potentially infectious.
Oladunni Opeyemi, Astril Emmanuel-Ufuah, Great Okenwe, Victoria Abiodun Adedoyin, Chigozirim Omirenyi Ofieh, Favour Ajagbe Tijesunimi
Journal of Gynecological Research and Obstetrics, Volume 8, pp 014-021; https://doi.org/10.17352/jgro.000109

Abstract:
Background: Period poverty, which includes a lack of access to menstrual products, can lead to poor menstrual hygiene by wearing pads or tampons for too long to manage what they have, absorbing menstrual blood with newspapers or dirty clothes, and not washing or washing the vagina with dirty water these unhealthy practices can lead to things like fungal infection, bacterial infection, yeast infection and Urinary Tract Infections (UTIs). Period poverty is a serious issue in Nigeria but is overlooked and understudied. The study assessed the level of period poverty among the respondents and the factors influencing period poverty. Methods: This study adopted a descriptive design to describe the factors associated with period poverty among public secondary school students in Ede, Osun state. A multistage sampling technique was used for the study. Descriptive and bivariate statistics were used to analyze the quantitative data, and the level of significance was α0.05. Results: The mean age was 14.2 ± 3.8 years. 29.8% were from JSS1, 25.3% were from JSS2, 25.0% were from SSS1, and 19.9% were from SSS2. Results revealed that the majority 79.5% experienced intense period poverty, 14.1% were rated average, and 6.4% experienced less intense period poverty. 72.4% had personal factors that can influence period poverty, while 27.6% had personal factors that might not influence period poverty. 70.6% gave responses that show the school having conditions that can contribute to period poverty while 29.4% gave responses that show the school having conditions that would not contribute to period poverty. 76.6% had background factors that could influence Period Poverty, while 23.4% had background factors that might not influence period poverty. Conclusion: Curbing these factors that influence (increase) the rate of period poverty would reduce its effects.
Stefos Spyridon, Stefos Theodor
Journal of Gynecological Research and Obstetrics, Volume 8, pp 007-013; https://doi.org/10.17352/jgro.000108

Abstract:
Pregnancy is a specific and critical period in a woman’s life. Some pregnant women face difficulty when performing effective oral hygiene care due to pregnancy-related vomiting symptoms. A hypersensitive vomit reaction in the third trimester of pregnancy is not frequent and may prevent the dental provider from successfully completing critical clinical stages resulting in poor treatment outcomes. Once pregnant women suffer an unpleasant gag reflex experience in a dental office, they may become phobic, delaying or postponing their dental treatment. The purpose of this article is to report a case of a 32-year-old woman, primigravida in the third trimester of pregnancy (32 weeks), partially edentulous with an exaggerated vomiting reaction, focusing on successful clinical management using a simple but effective table salt technique and proper fixed prosthesis design, as also to discuss the etiology, clinical symptoms and consequences of vomiting associated with late pregnancy during the dental, especially prosthodontics , treatment in such cases.
Tosun Hülya, Çiftçi Esra Karaca
Journal of Gynecological Research and Obstetrics pp 001-006; https://doi.org/10.17352/jgro.000107

Abstract:
Background: Demographic features such as low income, low education, and living in a crowded or single-parent family increase young girls’ premenstrual and menstrual symptoms such as pain, anxiety, and bleeding and negatively affect their healthy lifestyle. The purpose of the study was to analyze the relationship between healthy lifestyle behaviors and menstrual symptoms among young girls and their sociodemographic characteristics. Methods: This descriptive study was conducted on 1,130 students from four high schools providing full-time education in the Beylikduzu district of Istanbul between February 3, 2020, and March 1, 2020. Volunteer students whose families gave consent participated in the study. A personal identification form, the Menstrual Symptom Scale and the Healthy Lifestyle Behavior Scale-II (HLBS-II) were used to collect data in the study. All statistical analyses were performed using SPSS Statistics version 23. Results: It was found that economic status and painful menstruation negatively affected healthy lifestyle behaviors while living with one’s nuclear family positively affected healthy lifestyle behaviors; furthermore, chronic disease, painful menstruation, and family types other than the nuclear family negatively affected menstrual symptoms. Conclusion: Poor economic status and painful menstruation negatively affected healthy lifestyle behaviors, and chronic disease, painful menstruation and family type other than the nuclear family negatively affected menstrual symptoms.
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