Microbiology Spectrum

Journal Information
EISSN: 21650497
Total articles ≅ 3,703

Latest articles in this journal

, Illiassou Hamidou Soumana, Katie L. Reagin, Preston Dihle, , Kimberly D. Klonowski, ,
Published: 2 February 2023
Abstract:
The interplay of microbial species in the upper respiratory tract is important for the ability of an incoming pathogen to establish and, in the case of pathogenic organisms, cause disease in a host. Here, we demonstrate that B. bronchiseptica efficiently colonizes and concurrently displaces the commensal nasal cavity microbiota, negating the ability of influenza A virus to establish infection.
Liping Zhou, Deqiang Han, Xingzhe Wang,
Published: 2 February 2023
Abstract:
This study provides evidence for the neuroprotective activities of human umbilical cord MSCs from the aspect of anti-inflammation actions. hMSCs inhibit the NLRP3 inflammasome and MPTP-induced inflammation in both brain and periphery to relieve the degenerative changes in dopaminergic neurons in PD mice. Furthermore, as an additional therapeutic agent, probiotic formulation VSL#3 interacts with hMSCs in suppressing the NLRP3 inflammasome as well as the central and peripheral anti-inflammatory effects to exert neuroprotective actions in PD mice without altering the actions of hMSCs, suggesting the potential of VSL#3 as an adjuvant therapy in PD treatment.
Sophie Graffius, Jaime Felipe Guerrero Garzón, Martin Zehl, Petra Pjevac, Rasmus Kirkegaard, Mathias Flieder, Alexander Loy, Thomas Rattei, Andrew Ostrovsky,
Published: 2 February 2023
Abstract:
A large body of research is dedicated to marine sponges, filter-feeding animals harboring rich bacterial microbiomes believed to play an important role in protecting the host from predators and infections. Freshwater sponges have received so far much less attention with respect to their microbiomes, members of which may produce bioactive secondary metabolites with potential to be developed into drugs to treat a variety of diseases.
Shen Li, Li Yang, Yanling Li, Wenxing Yue, Shuyu Xin, Jing Li, Sijing Long, Wentao Zhang, Pengfei Cao,
Published: 2 February 2023
Abstract:
When establishing persistent infection in most human hosts, EBV is usually latent. How the viral latency is maintained in cells remains largely unknown. c-Myc was recently reported to act as a controller of the lytic switch, while whether and how EBV regulates it remain to be explored.
Sho Yamashita, , Keita Nakatomi, Yuko Sakurai, Hiroe Shuto, Noriko Sato, Yoshihiro Mizoguchi, Maki Uehara, Nobutaka Nakashima, Isamu Okamoto, et al.
Published: 1 February 2023
Abstract:
Influenza virus, RSV, adenovirus, and rhino/enterovirus were the major respiratory viruses before COVID-19 pandemic. Circulating respiratory viruses may have been affected by our strong quarantine policy during the COVID-19 pandemic.
Dina Ramić, Blaž Jug, Katarina Šimunović, Magda Tušek Žnidarič, Urban Kunej, Nataša Toplak, Minka Kovač, Marjorie Fournier, Polona Jamnik, , et al.
Published: 1 February 2023
Abstract:
Campylobacter jejuni is the world's leading foodborne bacterial pathogen of gastrointestinal disease in humans. C. jejuni is a fastidious but widespread organism and the most frequently reported zoonotic pathogen in the European Union since 2005. This led us to believe that C. jejuni , which is highly sensitive to stress factors (starvation and oxygen concentration) and has a low growth rate, benefits significantly from the luxS gene.
Na Pan, Yang Liu, Haochi Zhang, Ying Xu, Xuemei Bao, Shouxin Sheng, Yanchen Liang, Bohui Liu, Yueqing Lyu, Haotian Li, et al.
Published: 1 February 2023
Abstract:
We systematically screened and evaluated protective effects of engineered Lactobacillus against S. aureus infection in terms of differing delivery vehicle strains and S. aureus antigens and in localized and systemic infection models. Engineered L. reuteri was developed and showed strong protective effects against both types of S. aureus -induced infection.
Yizhak Hershko, Amos Adler, , Michal Meir
Published: 1 February 2023
Abstract:
Mycobacterium abscessus chronically infects patients with preexisting lung diseases, leading to progressive deterioration in pulmonary function. The common perception among clinicians is that the rough phenotype is associated with progressive disease and severe clinical course, manifested as a widespread inflammatory response and resistance to antibacterials.
José Ángel Moreno-Cabezuelo, Guadalupe Gómez-Baena, Jesús Díez,
Published: 1 February 2023
Abstract:
Glucose uptake by marine picocyanobacteria has been previously described and strongly suggests they are mixotrophic organisms (capable of using energy from the sun to make organic matter, but also to directly use organic matter from the environment when available). However, a detailed analysis of the effects of glucose addition on the proteome and metabolome of these microorganisms had not been carried out.
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