Affected by human activities, the living environment of aquatic wildlife in Bohai Bay and Huanghai Bay of our country is deteriorating day by day. In accordance with the animal protection law and other relevant laws and regulations, our country has formulated an action plan and an action plan for the protection of leopard seals. The Action Plan is based on the multi-dimensional vision of the natural environment, the balance of nature, sustainable development and human care, in 2021, the Leopard Seal is listed as a first-class protected animal in the country. This paper expounds on the survival status of the spotted seal population by searching the judgments of criminal cases, administrative cases and on-the-spot investigation on the judgment network, this paper analyzes the main reasons for the endangered population of spotted seal and puts forward the corresponding protection countermeasures.

Aim: In this study, it was aimed to determine the thoughts and attitudes of young adults about HPV and HPV vaccines. Methods: This study was planned as a cross-sectional study to determine the knowledge levels and attitudes of young people living in a settlement in the middle of Turkey about the HPV vaccine. The research was conducted with 870 young adults between 1-30 November 2022. Results: The average age of the young people participating in the study was 20.49 ± 2.15 years, 60.9% of them were male. 61% have not heard of the PAP-Smear test before, 51.3% do not know what HPV is, only 17.7% have HPV by vaccination, 8% have HPV vaccine, 24.75% 37.9% of them stated that they wanted to have the HPV vaccine and that the HPV vaccine should be free of charge. Conclusion: It was determined that the knowledge level of young adults about HPV and HPV vaccine, in general, was very low, only one out of four people wanted to be vaccinated against HPV, and the rate of vaccination was very low. Even if the vaccine is free in our country, it is thought that the vaccination rates will be low.

Introduction: The vascular system has a high frequency of variations, which are of interest to both anatomists and clinicians, as well as surgeons. The renal vasculature is quite variable and given the significant number of variations, the latter has proven difficult to classify. The conflicting terminology is often the cause of a poor understanding of the clinical implications of the presence of such variations. We present a case of bilateral accessory arteries, which can be classified as polar and extrahilar. Background: Variants of the renal artery are a common finding with additional vessels in up to 30% of cases. The supernumerary arteries are of end type and often enter the kidney outside the hilum. The arteries that enter the kidney in its upper or lower pole are referred to as polar arteries. Case report: During a routine dissection of a 73-year-old, female, formalin-fixed cadaver at the department of Anatomy, Histology and Embryology at the Medical University of Sofia, we discovered a right inferior polar artery and a left extrahilar renal artery, both originating from the abdominal aorta. The right kidney was located at the level of L1- L2. Conclusion: Accessory renal vessels have been an object of multiple cadaveric and in vivo studies. The terminology and classification of such variations in regard to their origin, course, and site of entrance in the kidney are conflicting and often prove inadequate to convey the clinical and surgical importance of their presence. Knowledge of such variants is of great significance when performing an explorative laparotomy, kidney transplantation, and assessing kidney injury. Such vessels are as well associated with cases of hypertension, hydronephrosis and other conditions.

Global events, such as climate change, the food crisis, or the advance of the COVID-19 pandemic, show that the world needs new integrated dynamic processes. In dealing with the pandemic, exchanges between the scientific community, trained personnel, and the training of professionals, as well as the strengthening of local capacities to deal with the health crisis, the dispatch of health material, medical personnel, etc., have been very useful.

More and more data are showing a link between hemoglobin genotypes and Plasmodium falciparum malaria. In order to establish the prevalence of hemoglobin genotype variants and their association with P. falciparum malaria in children receiving postpartum care at Faith Alive Foundation Jos, Plateau State, we study the distribution of these variants. From each sample, thick and thin blood films were created, and hemoglobin genotypes were determined using electrophoresis. Out of 172 samples examined, 131 (76.16%) were infected with P. falciparum malaria while 41 (23.84%) were not infected. There was no significant difference (p > 0.05) in the distribution of P. falciparum malaria in relation to hemoglobin genotypes. P. falciparum malaria was highest in AA with 92 (70%) and SS was the least with 12 (9%). There was no significant difference (p > 0.05) in th+++e prevalence of P. falciparum malaria in relation to age. P. falciparum malaria infection was highest in the age group ≥ 12 months than age group 0 - 11 months. There was no significant difference (p > 0.05) in the prevalence of P. falciparum malaria in relation to sex. The result depicted that P. falciparum malaria infects more males than females. There was also no significant difference (p > 0.05) in the prevalence of P. falciparum malaria in relation to months. The month of September had the highest prevalence of P. falciparum malaria followed by October and August respectively. It is, therefore, recommended that public health education campaigns for mothers and healthcare givers be intensified to create awareness that will lead to the reduction of human-vector contact, especially in children.

Background: Epidermolysis Bullosa (EB) is a heterogeneous genetic disorder with skin fragility. Only a few cases have been reported in Thailand. This study aims to determine the clinical characteristics, complications, and outcomes of EB stratified by subtype. Methods: A retrospective single-center study of EB patients at the Dermatology Unit, Queen Sirikit National Institute of Child Health, was reviewed from January 1, 2002, to December 31, 2021. Diagnosis is based on clinical manifestations and some skin biopsies. Results: There were 38 enrolled patients, age range from 0 to 25 years with a male-to-female ratio of 1.1:1. Family history of EB and consanguineous marriage were found in 6 cases and 2 cases, respectively. The most common type of EB was dystrophic EB (DEB) (26 cases) (68.4%), including recessive DEB in 15 cases (39.5%) and dominant DEB in 11 cases (28.9%). Other types were EB simplex in 10 cases (26.3%) and junctional EB in 2 cases (5.3%). Common complications were cutaneous bacterial infection (39.5%), anemia (31.6%), failure to thrive (18.4%), and protein energy malnutrition (15.8%). Musculoskeletal (21.1%), gastrointestinal (13.2%), and eye complications (7.9%) were exclusively found in DEB. Nineteen patients (50%) received regular follow-ups with a median duration of 9 months (range = 0.5 to 248 months). The mortality rate was 31.6% (6/19). Five cases died from bacterial sepsis, while one case died from metastatic squamous cell carcinoma. Conclusion: DEB is the most common type of EB in Thai children, and bacterial sepsis is the predominant cause of death. Further multicenter and molecular genetic studies are recommended for a definite diagnosis.

Introduction: Identification of COVID-19 patients at high risk of mortality is crucial to improve patient management. Our study aimed to identify mortality risk factors at the COVID-19 Intensive Care Unit (ICU), in Mahdia. Methods: We conducted a prospective study including patients admitted to the COVID-19 ICU at University Hospital Tahar Sfar Mahdia (September 2020 to February 2021). We used “The RAPID CORE CASE REPORT FORM” developed by the World Health Organization. Results: A total of 119 patients were included (60.5% male). The average age was 61.9 ± 12 years. During their stay, 51.8% of them had invasive ventilation, 31.3 % required vasopressors intake and 50.9% required a prone position. The mortality rate was 47.1%. Severe acute respiratory distress syndrome and Health Care Associated Infections (HAI) were associated with a higher risk of mortality (64.9% vs 17.8%; p < 0.001 and 81.1% vs 18.2 %; p < 0.001 respectively). Mortality was higher among intubated patients (79.7% vs 14.5%; p < 0.001). The mean Acute Physiology and Chronic Health Evaluation II (APACHII) score were higher in deaths than in survivors ((15.02 ± 7.6 vs 10.63 ± 5.31; p = 0.02). Low oxygen saturation on admission was associated with a higher risk of mortality (91.1% ± 6.44 vs 86% ± 11.25; p = 0.004). Binary logistic regression showed increased odds of mortality with health-acquired infection (OR, 7.96 [95% CI, 2.28 - 27.7], severe acute respiratory distress syndrome (OR, 4.04 [95% CI, 1.11 - 14.73]) and invasive ventilation (OR, 12.23 [95% CI, 3.31 – 45.2]). Conclusion: Interventions preventing the risk factors are needed to improve the prognosis of Covid-19 patients.

The social significance of public health and current scientific practice poses new responsibilities that drive scientific-medical societies to assume a public commitment, freely adopted and voluntary responsibility expressed through a Code of Good Practices [1],

Objectives: The aim of this study was to evaluate the effects of a global health promotion intervention in the workplace on cardiovascular risk factors and weight-related outcomes in offices workers after two years. Methods: This nonrandomized retrospective observational study analyzed data of two medical check-up of 728 office workers, over 40 years old: intervention group (376) and control (352) at baseline and after 2 years of a global health promotion program (based on nutrition, physical activity, and mental health) of mixed approach (individual, group and organizational) in the workplace of the intervention group. Results: Systolic and diastolic blood pressure experienced a statistically significant decrease (p ˂ 0.05) at 2 years of -0.94 mm Hg and -0.79 mm Hg in the intervention group versus the control group whose changes were + 0.02 mm Hg and -0.38 mm Hg. Glucose also decreased 1.59 mg/dl more in the intervention group. Lipids, smoking, body mass index or waist circumference did not undergo relevant modifications. Conclusion: This program improved blood pressure and glucose of office workers after two year follow-up, even among employees with low cardiovascular risk. However, according to the findings, this intervention was not as effective as expected in improving weight-related outcomes and cardiovascular risk in an office worker population. Companies should strengthen, not only an overall health intervention, but also individual and personalized advice in the fight against cardiovascular risk.

Digital health has come into reality, thanks to the new technologies such as Artificial Intelligence and Deep learning, contributing in a transcendental way to advances in the prevention, diagnosis, treatment and monitoring of diseases; In addition, this occurs at a crucial moment, marked by the growing prevalence of chronic diseases and the increase in life expectancy.