Biomedicine and Chemical Sciences

Journal Information
ISSN / EISSN: 29575826 / 2790296X
Total articles ≅ 41

Latest articles in this journal

Sajjad Kathem Ashour, Haider Abd Jabbar Al-Ammar, Yasmine Hamza Sharif
Biomedicine and Chemical Sciences, Volume 1, pp 306-311; https://doi.org/10.48112/bcs.v1i4.303

Abstract:
Preeclampsia (PE) is a serious illness that can harm both mothers and unborn children and may even be fatal. It contributes significantly to maternal fatalities in underdeveloped countries. PE, which affects 2%–3% of women who are pregnant after 20 weeks of pregnancy, is marked by proteinuria and hypertension. PE is a significant condition that plays a significant role in maternal fatalities in underdeveloped countries and is a significant cause of death for both mothers and newborns. Each year, around 60,000 maternal fatalities occur in the world. Serum interleukin-6 (IL-6) was measured in pregnant women during the first trimester and second trimesters. IL-6 was necessary to establish serum biomarkers that can accurately predict the onset of preeclampsia. In a prospective cohort study that was conducted in the Obstetrics and Gynecology Department and Antenatal Care Unit at Maternity and Pediatrics Teaching Hospital in AL-Diwaniyah – Iraq, 160 pregnant patients between the years of 20 and 40 who were normotensive and had gestational ages of 10 to 13 weeks were included in this research between August 2021 and May 2022. Bioassays for IL-6 were conducted after blood samples were obtained. At the end of the study, it was confirmed that for women with pre-eclampsia (n = 33, 22.0%) and those women with no pre-eclampsia (n = 117, 78.0 %), there was no significant difference in the level between the preeclampsia and no preeclampsia group (p > 0.05).
, Thaer M. Salman
Biomedicine and Chemical Sciences, Volume 1, pp 249-253; https://doi.org/10.48112/bcs.v1i4.257

Abstract:
In southern Basrah in Iraq, this research is aimed at measuring the concentrations of Boron 10B5. Measuring the water wells and water samples collected at 43 different locations were carried out using the Inductively coupled plasma/Optical Emission Spectrometry (ICP-OES) method. The concentration ranged from 0.2 mg/L (Al Marbad District) to 9.3 mg/L (Al Shuaiba farm 2). The study's findings are given and compared to those of other studies. These observations could be used to make an additionally unique contribution to the preservation and application of water quality standards to related organizations of radioactive contaminant-free samples required for humans if an incident of contamination occurs. Furthermore, 43 surface water samples were found to be more boron-like than detected levels. The increase in water flow outside the root level by the monsoon rain is responsible. This is due to acute boron contamination will therefore soon occur.
Biomedicine and Chemical Sciences, Volume 1, pp 259-263; https://doi.org/10.48112/bcs.v1i4.264

Abstract:
Polycystic ovarian syndrome can be defined as an endocrine disorder that most affects the reproductive system of women of childbearing age; its causes are not exactly known. However, the majority of the experts agree that it is a multifactorial entity with multiple factors. Genetics is becoming increasingly important. In recent years, several genes that are involved in the pathogenic processes of this syndrome have been identified. Within these, the most important ones are the ones that encode steroidogenesis enzymes and insulin receptors, as well as other hormones that are associated with the actions of insulin and gonadotropins and their receptors. The results obtained included 1) women with PCOS had significantly lower levels of adiponectin compared to controls. Adiponectin levels were significantly lower in both lean and obese women with PCOS compared to the control group. 2) PCOS women had significantly higher levels of LH, FSH, LH/FSH ratio, and total testosterone compared to controls. 3) Both lean and obese PCOS women had significantly higher levels of LH, LH/FSH ratio, and total testosterone compared to the control group, however, FSH levels were significantly increased only in obese PCOS women compared to controls. 4) PCOS women had significantly higher levels of total cholesterol, triglycerides, LDL cholesterol, VLDL cholesterol, and lower levels of HDL-cholesterol compared to controls. 5) Both lean and obese PCOS women had significantly higher levels of total cholesterol, triglycerides, LDL cholesterol, and VLDL cholesterol compared to controls. Only obese PCOS women had significantly lower levels of HDL-cholesterol compared to the controls. 6) The genotype analysis of FSHR gene polymorphism showed that the heterozygote Ala/Thr genotype was significantly more frequent in PCOS patients than in controls (64.1% versus 40%).
Biomedicine and Chemical Sciences, Volume 1, pp 215-224; https://doi.org/10.48112/bcs.v1i4.149

Abstract:
CdO nanoparticles show a strong peak of Plasmon absorption in ultraviolet-visible zone. A strong interaction exists between the surface of CdO nanoparticles and aryl mercaptan compounds. Aryl mercaptan compounds cause to aggregation of CdO nanoparticles linked to DNA/RNA and hence, lead to widening of peak Plasmon of CdO nanoparticles surface at 550 (nm) and emerging a new peak at higher wavelength. In the current project, this optical characteristic of CdO nanoparticles is used to time investigate of interaction between different aryl mercaptanes and CdO nanoparticles. The results were shown that aryl mercaptan compounds with shorter chain length interact faster with CdO nanoparticles. Therefore, a simple and fast method for identification of aryl mercaptanes with various chain length using red shift in surficial Plasmon absorption is presented.
Lina Saadi,
Biomedicine and Chemical Sciences, Volume 1, pp 241-248; https://doi.org/10.48112/bcs.v1i4.252

Abstract:
The metal complexes of Azo dye; 4,4'-((methylene bis(3,l-phenylen)) bis (diazene-l,2-diyl)) bis(1,3-Benzenediol) are produced from 4,4`- methylenedianiline and Resorcinol were synthesized and characterized by using several analytical and spectral techniques. The ligand and its complexes were characterized by many chemo-physic methods like NMR, IR, UV-Vis, molar conductance measurement, analytical measurement, and melting point. The conditions of optimal reaction (for instance reagent concentration, pH etc) were studied and the analytical figures of merit such as limit of detection, linearity, sensitivity etc) were obtained.
, Azhar A. Al-Attraqchi, Amar Kasim Muhmmed
Biomedicine and Chemical Sciences, Volume 1, pp 225-233; https://doi.org/10.48112/bcs.v1i4.235

Abstract:
The study aimed to assess the frequency of invasive fungal infection in patients with respiratory diseases by conventional and molecular methods. This study included 117 Broncho alveolar lavage (BAL) samples were collected from patients with respiratory disease (79 male and 38 female) with ages ranged between (20-80) years, who attended Medicine Baghdad Teaching hospital and AL-Emamain AL-Khadhymian Medical City, during the period from September 2019 to April 2020. The results in PCR versus culture methods in this study showed that out of 117 samples of fungal infections 30(25.6 %) were detected by culture method, while the 24(20.5%) samples were detected by PCR technique, the most commonly diagnosed pathogenic fungi is Candida spp. followed by Aspergillus spp. By considering the culture method as a gold standard against the PCR technique, the results show that the sensitivity and specificity of PCR were (86.6%) and (100%) respectively.
Marwa Husain Abdullah Mohi Al-Kahfaji
Biomedicine and Chemical Sciences, Volume 1, pp 254-258; https://doi.org/10.48112/bcs.v1i4.259

Abstract:
All across the world, skin diseases are rather frequent. The likelihood of pediculosis capitis (0.2-35 percent, 6.9-35 percent in Sub-Saharan Africa in addition to other parts of South Africa. ), pyoderma (prevalence range 0.2-35 percent, 6.9–35% in Sub-Saharan Africa and other parts of South Africa, tinea capitis (1–19.7%), scabies (0.2–24%, 1.3–17% in Sub-Saharan Africa), and viral skin illnesses (0.4–9%, mainly molluscum contagiosum,0-57 percent). A bacterial skin infection is the most frequent kind of skin infection. Numerous bacterial skin infections have been linked to necrotizing fasciitis, scarlet fever, erysipelas, erythrasma, abscesses, folliculitis, furunculosis, and impetigo. Additionally, ecthyma, furunculosis, and mycobacterium skin disorders are covered in this review. Recent studies have revealed modifications in the causes and remedies of bacterial skin infections. In the United States, the prevalence of MRSA (methicillin-resistant Staphylococcus aureus) is rising.
, Hassan Hadi Kadhim
Biomedicine and Chemical Sciences, Volume 1, pp 270-277; https://doi.org/10.48112/bcs.v1i4.284

Abstract:
In this research, a new method was used to determine the amount of iron in water, by using the colour biosensor of the smart-phone device as a biosensor for the chromatic intensity of the samples images that are examined through a program (colour meter) downloaded to the phone. The concentration of the samples is measured from the value of the basic colours (red, green, blue) (RGB) for recorded video from a device (Galaxy J7 prime 2). An accessory for the mobile device is designed from plastic (black acrylic). In the form of a dark box from the inside equipped with a flow cell and a mirror reflecting the flash light emitted by the mobile device and a green filter complementing the red colour, and a micro switch connected to a smart-phone device via earphones, and the device is attached to the accessory by the device case. The calibration curve for this method was in the range of mg/L (1-8), the correlation coefficient (R2 ) was equal to (0.999), the limit of detection was in the amount of (0.2) mg/L, and the relative standard deviation (RSD%) for the concentration was (4) mg/L, for which the examination was repeated (10) times, and its value was (0.6 %), and the recovery value (Recovery%) was equal to (101.5 %).
R Kumaar Prathipati, V Harsha Shastri, Madhavi Kolukuluri, Radha Dharavathu, Donthireddy Sudheer Reddy, B N Siva Rama Krishna
Biomedicine and Chemical Sciences, Volume 1, pp 207-214; https://doi.org/10.48112/bcs.v1i4.84

Abstract:
The clustering of data series was already demonstrated to provide helpful information in several fields. Initial data for the period is divided into sub-clusters Recorded in the data resemblance. The grouping of data series takes 3 categories, based on which users operate in frequencies or programming interfaces on original data explicitly or implicitly with the characteristics derived from physical information or through a framework based on raw material. The bases of series data grouping are provided. The conditions for the evaluation of the outcomes of grouping are multi-purpose time constant frequently employed in dataset grouping research. A clustering method splits data into different groups so that the resemblance between organisations is better. K-means++ offers an excellent convergence rate compared to other methods. To distinguish the correlation between items the maximum distance is employed. Distance measure metrics are frequently utilized with most methods by many academics. Genetic algorithm for the resolution of cluster issues is worldwide optimization technologies in recent times. The much more prevalent partitioning strategies of large volumes of data are K-Median & K-Median methods. This analysis is focusing on the multiple distance measures, such as Euclidean, Public Square and Shebyshev, hybrid K-means++ and PSO clubs techniques. Comparison to orgorganization-basedthods reveals an excellent classification result compared to the other methods with the K++ PSO method utilizing the Chebyshev distance measure.
, Shayma Muhsen Ahmad, Dhea Sh. Zagheer
Biomedicine and Chemical Sciences, Volume 1, pp 234-240; https://doi.org/10.48112/bcs.v1i4.246

Abstract:
In this short review definition, mechanism, and recent developments of the Stetter reaction, in the period last ten years from 2011 to 2021 are presented. This reaction comprises N-heterocyclic carbene (NHC)-catalyzed umpolung of aldehydes followed by their capturing with activated carbon-carbon double bonds (Michael acceptors). This work includes also progresses in the inter-molecular and intra-molecular versions and enantioselective transformations. Underscoring the recent advances in the applications of Stetter reaction in the synthesis of various heterocyclic systems and total synthesis of natural products have been also introduced.
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