Mathematical Modelling and Numerical Simulation With Applications

Journal Information
EISSN: 27918564
Published by: Mehmet Yavuz
Total articles ≅ 31

Latest articles in this journal

Adam Hassan Adoum, Mahamat Saleh Daoussa Haggar, Jean Marie Ntaganda
Mathematical Modelling and Numerical Simulation With Applications, Volume 2, pp 244-251; https://doi.org/10.53391/mmnsa.2022.020

Abstract:
In this paper, we focus on modelling the glucose-insulin system for the purpose of estimating glucagon, insulin, and glucose in the liver in the internal organs of the human body. A three-compartmental mathematical model is proposed. The model parameters are estimated using a nonlinear inverse optimization problem and data collected in Chad. In order to identify insulin and glucose in the liver for type 2 diabetic patients, the Sampling Importance Resampling (SIR) particle filtering algorithm is used and implemented through discretization of the developed mathematical model. The proposed mathematical model allows further investigation of the dynamic behavior of hepatic glucose, insulin, and glucagon in internal organs for type 2 diabetic patients. During periods of hyperglycemia (i.e., after meal ingestion), whereas insulin secretion is increased, glucagon secretion is reduced. The results are in agreement with empirical and clinical data and they are clinically consistent with physiological responses.
Saeed Ahmad, ,
Mathematical Modelling and Numerical Simulation With Applications, Volume 2, pp 228-243; https://doi.org/10.53391/mmnsa.2022.019

Abstract:
For the sake of human health, it is crucial to investigate infectious diseases including HIV/AIDS, hepatitis, and others. Worldwide, the recently discovered new coronavirus (COVID-19) poses a serious threat. The experimental vaccination and different COVID-19 strains found around the world make the virus' spread unavoidable. In the current research, fractional order is used to study the dynamics of a nonlinear modified COVID-19 SEIR model in the framework of the Caputo-Fabrizio fractional operator with order b. Fixed point theory has been used to investigate the qualitative analysis of the solution respectively. The well-known Laplace transform method is used to determine the approximate solution of the proposed model. Using the COVID-19 data that is currently available, numerical simulations are run to validate the necessary scheme and examine the dynamic behavior of the various compartments of the model. In order to stop the pandemic from spreading, our findings highlight the significance of taking preventative steps and changing one's lifestyle.
Ioannis Dassios
Mathematical Modelling and Numerical Simulation With Applications, Volume 2, pp 221-227; https://doi.org/10.53391/mmnsa.2022.018

Abstract:
In this article, we consider a class of systems of differential equations with multiple delays. We define a transform that reformulates the system with delays into a singular linear system of differential equations whose coefficients are non-square constant matrices, and the number of their columns is greater than the number of their rows. By studying only the singular system, we provide a form of solutions for both systems.
, Miraç Kayhan, Armando Ciancio
Mathematical Modelling and Numerical Simulation With Applications, Volume 2, pp 211-220; https://doi.org/10.53391/mmnsa.2022.017

Abstract:
In this paper, we use an effective method which is the rational sine-Gordon expansion method to present new wave simulations of a governing model. We consider the (1+1)-dimensional conformable Fisher equation which is used to describe the interactive relation between diffusion and reaction. Various types of solutions such as multi-soliton, kink, and anti-kink wave soliton solutions are obtained. Finally, the physical behaviours of the obtained solutions are shown by 3D, 2D, and contour surfaces.
Mathematical Modelling and Numerical Simulation With Applications, Volume 2, pp 197-210; https://doi.org/10.53391/mmnsa.2022.016

Abstract:
We propose a new epidemic model to study the coinfection dynamics of COVID-19 and bacterial pneumonia, which is the first model in the literature used to describe mathematically the interaction of these two diseases while considering two infection ways for pneumonia: community-acquired and hospital-acquired transmission. We show that the existence and local stability of equilibria depend on three different parameters, which are interpreted as the basic reproduction numbers of COVID-19, bacterial pneumonia, and bacterial population in the hospital. Numerical simulations are performed to complement our theoretical analysis, and we show that both diseases can persist if the basic reproduction number of COVID-19 is greater than one.
Amine Moustafid
Mathematical Modelling and Numerical Simulation With Applications, Volume 2, pp 187-196; https://doi.org/10.53391/mmnsa.2022.015

Abstract:
The aim of the paper is to study a cancer model based on anti-angiogenic therapy and radiotherapy. A set-valued analysis is carried out to control the tumor and carrying capacity of the vasculature, so in order to reverse tumor growth and augment tumor repair. The viability technique is used on an augmented model to solve the control problem. Obtained control is a selection of set-valued map of regulation and reduces tumor volume to around zero. A numerical simulation scheme with graphical representations and biological interpretations are given.
Mathematical Modelling and Numerical Simulation With Applications, Volume 2, pp 177-186; https://doi.org/10.53391/mmnsa.2022.014

Abstract:
The purpose of this paper is to find approximate solutions to the fractional telegraph differential equation (FTDE) using Laplace transform collocation method (LTCM). The equation is defined by Caputo fractional derivative. A new form of the trial function from the original equation is presented and unknown coefficients in the trial function are computed by using LTCM. Two different initial-boundary value problems are considered as the test problems and approximate solutions are compared with analytical solutions. Numerical results are presented by graphs and tables. From the obtained results, we observe that the method is accurate, effective, and useful.
Mathematical Modelling and Numerical Simulation With Applications, Volume 2, pp 164-176; https://doi.org/10.53391/mmnsa.2022.013

Abstract:
This article deals with a Caputo fractional-order viral model that incorporates the non-cytolytic immune hypothesis and the mechanism of viral replication inhibition. Firstly, we establish the existence, uniqueness, non-negativity, and boundedness of the solutions of the proposed viral model. Then, we point out that our model has the following three equilibrium points: equilibrium point without virus, equilibrium state without immune system, and equilibrium point activated by immunity with humoral feedback. By presenting two critical quantities, the asymptotic stability of all said steady points is examined. Finally, we examine the finesse of our results by highlighting the impact of fractional derivatives on the stability of the corresponding steady points.
Muhammad Abubakar Isah,
Mathematical Modelling and Numerical Simulation With Applications, Volume 2, pp 147-163; https://doi.org/10.53391/mmnsa.2022.012

Abstract:
This work investigates the complex Ginzburg-Landau equation (CGLE) with Kerr law in nonlinear optics, which represents soliton propagation in the presence of a detuning factor. The φ^6-model expansion approach is used to find optical solitons such as dark, bright, singular, and periodic as well as the combined soliton solutions to the model. The results presented in this study are intended to improve the CGLE's nonlinear dynamical characteristics, it might also assist in comprehending some of the physical implications of various nonlinear physics models. The hyperbolic sine, for example, appears in the calculation of the Roche limit and gravitational potential of a cylinder, while the hyperbolic cotangent appears in the Langevin function for magnetic polarization. The current research is frequently used to report a variety of fascinating physical phenomena, such as the Kerr law of non-linearity, which results from the fact that an external electric field causes non-harmonic motion of electrons bound in molecules, which causes nonlinear responses in a light wave in an optical fiber. The obtained solutions' 2-dimensional, 3-dimensional, and contour plots are shown.
Seyma Tuluce Demiray, Ugur Bayrakci
Mathematical Modelling and Numerical Simulation With Applications, Volume 2, pp 1-8; https://doi.org/10.53391/mmnsa.2022.021

Abstract:
The basic principle of this study is to obtain various solutions to the (1+1) dimensional Mikhailov-Novikov-Wang integrable equation (MNWIE). For this purpose, the generalized exponential rational function method (GERFM) is applied to this equation. Thus, several trigonometric functions, hyperbolic functions, and dark soliton solutions to the studied equation are acquired. In this way, some new solutions to the equation that have not been presented before have been obtained. In addition, 2D and 3D graphics of the acquired solutions are drawn for specific values. The obtained results and the graphic drawings of the results have been provided by using Wolfram Mathematica 12.
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