Jurnal Kesehatan Islam : Islamic Health Journal

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ISSN / EISSN: 2303002X / 26158345
Total articles ≅ 47

Latest articles in this journal

Andri Tilaqza, Merlita Herbani
Jurnal Kesehatan Islam : Islamic Health Journal, Volume 10, pp 45-52; https://doi.org/10.33474/jki.v10i2.13821

. Hypertension is a disease that is often occurred in every country, including Indonesia. Hypertension is one of the risk factors that lead to cardiovascular disease. Guazuma ulmifolia Lamk are one of the plants used empirically as antihypertensive in Indonesia, but research on the antihypertensive potential of its leaves has never been done before.The purpose of this study was to predict the potential activity and predict the pharmacokinetic of several compounds contained in Guazuma ulmifolia leaves. The Guazuma ulmifolia leaves compounds and captopril were docked to the Angiotensin-Converting Enzyme protein (PDB ID: 1O86). Mole­cular docking tests were performed using PyRx software while the visuali­zation analysis of molecular anchoring results was performed using Biovia Discovery Studio Visualizer software. Prediction of phar­macokinetic and physicochemical properties of the tested compounds was carried out using the pkCSM web page. Based on the molecular docking test, all compounds in Guazuma ulmifolia leaves have lower energy than the captopril. Kaempferitrin (-9.9 k/mol) and beta-sitosterol (-9.2 kcal/mol) had the lowest energy among other test compounds compared to captopril (-5.5 kcal/mol). Quercetin, kaempferol, and beta-caryophyllene were compounds that had similar interactions to the captopril based on the chemical interaction. All compounds had varied pharmacokinetic profiles but still had a fairly good profile.
Dian Novita W, Silvy Amalia Falyani
Jurnal Kesehatan Islam : Islamic Health Journal, Volume 10, pp 53-56; https://doi.org/10.33474/jki.v10i2.13823

:Orthosiphon aristatus is a potential herb as a source of antioxidants. It is known from previous research, that the active compounds O.aristatus include eupatorin, rosmarinic acid and sinensetin. The study of the potential approach of active compounds extracts O.aristatus with the in vitro methods DPPH (1,1-Difenil-2-Pikrilhidrazil) and in silico using the help of pyrex autodock vina software, with the help of visualization using biovia discovery studio and pymol. Results obtained from in vitro tests using DPPH showed the presence of antioxidant activity with yellow spotting markers against a purple background. Studies in silico show that O.aristatus extract is potentially an antioxidant compound, this is demonstrated through the presence of ligand bonds with glutathione peroksidase (GPX) receptors namely van der Waals bonds, hydrogen bonds and several other bonds.
Tri Wahyu Sarwiyata, Pyarkatariana Putri E. P., Mayvita Muntadiroh, Firsania Bunga W, Erfina Daniati, Erna Sulistyowati
Jurnal Kesehatan Islam : Islamic Health Journal, Volume 10, pp 84-91; https://doi.org/10.33474/jki.v10i2.13829

: The incidence of COVID-19 continued to increase due to human-to-human transmission. To prevent the transmission of COVID-19, the government applied self-quarantine regulation. However, health workers must continue to work, especially those located in big cities, such as Malang. One of the COVID-19 referral hospitals in Malang is the Rumah Sakit Islam Malang (RSI UNISMA). The high number of patients undergoing examination tests and handling COVID-19 treatment increased the workload of health workers at RSI UNISMA. Stress due to high workload had an impact on sleep quality disturbances. This study aimed to analyze the relationship between stress levels of health workers at RSI UNISMA on sleep quality during COVID-19.Methods: This type of research was an analytic observational study with a cross-sectional approach. The sampling technique used a simple random sampling method, with as many as 74 respondents. The questionnaire instrument was in the form of a google form regarding the Covid Perceived Stress Scale (COVID PSS-10 Items) which assesses stress levels and the Pittsburgh Sleep Quality Index (PSQI) which assesses sleep quality. Data analysis used SPSS 25.0 with fisher's exact test.Results: From a total of 74 respondents, there were 58 respondents who met the inclusion criteria. Based on statistical analysis, there was no relationship between stress levels and the sleep quality of UNISMA Hospital health workers during the COVID-19 pandemic (p > 0.05).Conclusion: There was no significant relationship between stress levels and the quality of sleep for health workers at RSI UNISMA during the COVID-19 pandemic. This can be caused by various factors, one of which is thought that the health worker is accustomed to doing work with a high level of stress or a deficiency in research methods such as classifying work units.
Indra Setiawan, Iwan Sis Indrawanto, Abi Noerwahjono, Abdi Malik Rahardjo
Jurnal Kesehatan Islam : Islamic Health Journal, Volume 10, pp 57-64; https://doi.org/10.33474/jki.v10i2.13824

Background Depression is a mood disorder that affects a person’s quality of life. This condition is influenced by the levels of monoamine compounds such as serotonin, norepinephrine, and dopamine in the brain. The decrease in monoamine levels leads to depressive symptoms. Lemon peel essential oil has an antidepressant potential, that contains phytochemicals, d-Limonene, which increase monoamine levels in the brain. Aromatherapy diffuser inhalation method is one kind of treatment route in depression. The mechanism of action is by breaking down the smaller essential oil particles so they penetrate quicker to the brain. Objective: To determine the effect of lemon peel (Citrus limon) aromatherapy inhalation diffuser method on immobility time of white rats (Rattus norvegicus Wistar strain) on the tail suspension test. Method: True Experimental with Post Test Only Control Group Design. Fifteen white male rats Wistar strain were divided into 5 groups. The positive control group was given stressors and saline induction intraperitoneally. In addition to stressors, the treatment group was also given lemon peel aromatherapy inhalation at a dose of 1%, 2.5%, and 5%. Measurement of immobility time was carried out by hanging the rats' tails through the tail suspension test method and the time of animals stopped moving for at least 1 second was calculated using a timer. Data were analyzed using the ANOVA test, Post Hoc test, Pearson correlation test, and Linear Regression test. Results and Discussion: ANOVA test showed a significant difference between groups (p = 0.017). The post Hoc test showed a significant difference (p <0.05) between the positive control and the P3 group (5%). The linear regression test obtained Adjusted R2 = 0.598 (inhalation of lemon peel aromatherapy gives an effect of 59.8%). The decrease of immobility time was due to the reduction of depression that was caused by the increase of monoamine level induced by d-limonene in lemon peel essential oil. Conclusion: The inhalation of lemon peel (Citrus limon) aromatherapy with diffuser method has the antidepressant effect that reduces the immobility time of depressed white rats (Rattus norvegicus Wistar strain).
Retna Gumilang, Meidyta Sinantryana Widyaswari, Zakiyyatur Rizkiyyah Husin
Jurnal Kesehatan Islam : Islamic Health Journal, Volume 10, pp 72-76; https://doi.org/10.33474/jki.v10i2.13827

Background: Psoriasis is a chronic inflammatory disease of the skin that characterized by firmly bound erythema plaques covered in thick squama and caused by multiple abnormalities of genetic, biochemical, immunologic, vascular with further severed by various other factors such as psychology, drugs, smoking, and alcohol consumption. Several studies revealed that psoriasis can increase the risk of cardiovascular diseases such as hypertension, however, the underlying pathophysiological mechanism has not been confirmed yet. This mechanism is probably attributed to increased levels of angiotensin-converting enzyme produce angiotensin II that regulates vascular tonus, endothelin-1 (ET-1) has been considered an important role in that vasoconstrictor proteins are potent, and increased plasma renin activity has been reported in patients with psoriasis. Purpose: In order to figure out the relationship between psoriasis and hypertension in psoriasis patients at the Outpatient Unit -RSI Jemursari Surabaya.  Methods: This study was observational analytics with cross sectional study design in 28 psoriasis patients at Outpatient Unit-RSI Jemursari Surabaya during 2017-2019, using total sampling technique. Secondary data from medical records was collected and further analyzed with spearman correlation tests. Result: The obtained significance value is 0.000 (p < 0.05), which represent a significant relationship between hypertension and psoriasis. the correlation coefficient is 0.757, which indicates the strength of a strong relationship between two variables. Conclusion: There is a significant association between Psoriasis and Hypertension.
Resa Budi Deskianditya, Anis Kusumawati, Yuhantoro Budi Handoyo Sakti, Naura Faisa Adiyanti, Sabrina Diva Wulandari
Jurnal Kesehatan Islam : Islamic Health Journal, Volume 10, pp 77-83; https://doi.org/10.33474/jki.v10i2.13828

: Circumcision is a minor surgery procedure that provides several benefits and is closely related to religious life.  Currently there are various methods in the action of circumcision.  The incindence of complication related to circumcision is low, but various variations of methods can affect complications.  The aim of this study is to present data on the incidence of pain and bleeding complication post clam method circumcision, as well as the factors associatd with both complications.  This study is an observa­tional analytic study with a cross-sectional method, with the research subject is medical record data at Klinik Rumah Sunatan Purwokerto for the period January 2017 – August 2020 which meets the inclusion criteria and excluded from exclusion criteria.  Data were collected and performed bivariate analysis of independent variables to complications of pain and bleeding using the Spearmen method for numerical variables and Chi square for nominal and ordinal variables, and follow up with the backward logisitic regression test.  There were 153 medical record data met the criteria, with 47.7 % pain complication and 38.6 % bleeding compllication.  Multivariate test showed a significant relationship between aged and pain (p = 0.039; B = -0.155) and bleeding complication (p = 0.003; B = -0.202), glans adhesions with pain (p = 0.007; B = 1.295) dan bleeding complication (p = 0.005; B = 1.346), and narrow prepucium and pain (p = 0.002; B = 1.294) and bleeding complication (p = 0.003; B = 1.200).  The conclusion of this study is the frequency of pain and bleeding complication were 47,7 % and 38,6 % respectively, and there was a significat relationship between age, glans adhesions, and narrow prepucium with pain and bleeding compli­cations.
Niken Faramida Sari, Ika Ratna Hidayati, Rizka Novia Atmadani
Jurnal Kesehatan Islam : Islamic Health Journal, Volume 10, pp 65-71; https://doi.org/10.33474/jki.v10i2.13825

: Diabetes Mellitus is a chronic disease characterized by high blood sugar levels in the body and can be caused by the pancreas not being able to produce enough insulin or because the cells in the body cannot respond to the insulin that has been produced. Management includes diet, physical activity, and administration of insulin injections and oral antidiabetic drugs (OAD). The objective of this study is to determine the relationship between knowledge of Type 2 Diabetes Mellitus patients and adherence to oral antidiabetic drug use at Singosari Public Health Center, Malang Regency. Research Methods: This research is analytic observational with a cross-sectional approach. Conducted in July 2021 at the Singosari Public Health Center, Malang Regency, by distributing questionnaires to 66 Type 2 Diabetes patients who met the inclusion criteria. The analysis was carried out with the SPSS application using descriptive and analytic methods. The results of the validity and reliability tests have met the requirements Result and Discussion:. Patients who have good knowledge of 74.2%, 18.2% good knowledge, and 7.6% poor knowledge. Patients with good knowledge were found to have 73% adherence to the use of OAD. Based on the results of the correlation test with Chi-Square, obtained a significant value of p = 0.000. Conclusion iit can be stated that there is a relationship between the knowledge of type 2 DM patients and adherence to the use of OAD at the Singosari Public Health Center, Malang Regency.
Luluk Rofiatul Mafluhah, Nour Athiroh Aboes Sjakoer, Ratna Djuniwati Lisminingsih
Jurnal Kesehatan Islam : Islamic Health Journal, Volume 10, pp 15-19; https://doi.org/10.33474/jki.v10i1.9350

HIV/AIDS cases have high rates in various countries. The reason is, HIV/AID cases are like an iceberg phenomenon, cases that are not seen and not recorded are more than cases that have been recorded. This study aims to describe the characteristics of HIV/AIDS sufferers in Sumenep District. This study used a descriptive qualitative method with a cross-sectional research design. There were 202 HIV/AIDS sufferers in Sumenep District, while the sample taken was 44 people from 3 Public Health Center. The results showed that based on gender the most were male (57.95%), while the age range was 25-49 years (75.25%), and the area with the most sufferers was Kalianget Sub-District (10.4%) of a total 202 sufferers. Referring to 44 patients who were sampled in this study, there were 39 patients (88.6%) who were married, the most transmission was sex (90.9%), most opportunistic infections were pulmonary tuberculosis (20.4%). Stage I (63.6%) is the most common clinical-stage suffered, and most HIV/AIDS sufferers have been infected for 1-2 years (93.2%). To break the chain of HIV/AIDS transmission, the public needs to be educated, from the mode of transmission to treatment, this also aims to eliminate the negative stigma against people with HIV/AIDS.Keywords: HIV/AIDS, Characteristics, Sumenep
Dyahris Koentarwi, Linda Oktaviana Sc, Nur Hidayati Azhar
Jurnal Kesehatan Islam : Islamic Health Journal, Volume 10, pp 40-43; https://doi.org/10.33474/jki.v10i1.11201

Latar Belakang. Pulse oksimetri (POX) banyak digunakan se­bagai deteksi PJB pada anak. Namun, akurasi pulse oxymetri sebagai pa­ra­meter tunggal kurang memuaskan. Oleh karena itu kombinasi peng­gunaan pulse oxymetri, auksultasi dan klinis dismorfisme fasial di­perkirakan dapat meningkatkan akurasi dan sensitivitas dalam deteksi PJB pada bayi baru lahir. Tujuan dari studi ini adalah untuk menilai sensitivitas, spesifisitas, nilai prediski positif, dan nilai prediksi negative dari kombinasi pulse oxymetri, auskultasi dan dismorfik feature. Metode. Studi potong lintang dilakukan di RSUD Dr Saiful Anwar Malang mulai Februari 2019 hingga Februari 2020. Pasien usia kurang dari 1 bulan yang dirujuk dari berbagai faskes di Malang Raya ke Departemen Anak RSUD Dr. Saiful Anwar Malang dengan curiga PJB. Subyek diukur saturasi oksigen, auksultasi, dan dismorfik feature kemudian dilakukan ekokardiografi untuk melihat adanya kelainan struktural jantung. Data diolah menggunakan Microsoft Excel dan dianalisa menggunakan software SPSS 22. Sensitivitas, spesifitas serta predictive value masing-masing dan kombinasi dihitung. Hasil. Subyek yang memenuhi kriteria penelitian ini berjumlah 274. Tiga belas subyek tidak didapatkan kelainan struktural jantung. Kelainan paling banyak ditemui adalah ASD diikuti dengan VSD. Empat puluh dua subyek memiliki saturasi kurang dari 90%. Murmur didapatkan pada 42 subyek. Dismorfik feature ditemukan pada 6 subyek. sensitivitas dan spesifiktas masing-masing parameter adalah 15,33% dan 84,64% untuk pulse oksimetri, 16,09% dan 100% untuk auskultasi, 2,3% dan 100% untuk dismorfik feature. Kombinasi ketiga metode meningkatkan sensitivitas menjadi 29,12% dan spesifitas menjadi 84,62% dengan PPV 97,44% LR+ sebesar 1,89. Kesimpulan. Penggunaan kombinasi pulse oxymetri, auskultasi dan dismorfik feature dapat meningkatkan sensitivitas diagnosis PJB pada bayi baru lahir di Malang Keywordspulse oxymetri, auskultasi, dismorfik feature, penyakit jantung bawaan
Tri Nurhudi Sasono
Jurnal Kesehatan Islam : Islamic Health Journal, Volume 10, pp 20-25; https://doi.org/10.33474/jki.v10i1.10968

HIV / AIDS is a disease caused by the Human Immunodeficiency Virus which lowers immunity by infecting and damaging the human immune system. Adherence to taking medication can increase the expectation and quality of life of PLWHA. The health condition of PLWHA is influenced by adherence to taking medication. The purpose of this study was to analyze the factors that influence medication adherence to people living with HIV / AIDS (PLWHA). The design of this research is analytic observational with aapproach cross sectional. The sample usedtechnique purposive sampling at NGO CAKAP AIDS Turen as many as 60 respondents. Retrieval of data using-based questionnaires. The statistical test is using multiple linear regression analysis. The results show that there is an influence of knowledge with a p-value of 0.017 <0.05 with a coefficient of 0.309, there is no influence on motivation with a p-value of 0.109> 0.05 with a coefficient of 0.107 and there is the effect of access to health services with a p-value of 0.012 <0.05 with a coefficient of 0.406. Based on these statistical results, it can be concluded that the factors that influence medication adherence are knowledge and access to health services.Keywords: Knowledge; Motivation and Access to Health Services; Compliance with Medication; HIV/AIDS
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