Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 with grinch

Late in 2020, two genetically-distinct clusters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with mutations of biological concern were reported, one in the United Kingdom and one in South Africa. Using a combination of data from routine surveillance, genomic sequencing and international travel we track the international dispersal of lineages B.1.1.7 and B.1.351 (variant 501Y-V2). We account for potential biases in genomic surveillance efforts by including passenger volumes from location of where the lineage was first reported, London and South Africa respectively. Using the software tool grinch (global report investigating novel coronavirus haplotypes), we track the international spread of lineages of concern with automated daily reports, Further, we have built a custom tracking website ( which hosts this daily report and will continue to include novel SARS-CoV-2 lineages of concern as they are detected.
Funding Information
  • European Research Council (725422)
  • Medical Research Council
  • Branco Weiss Fellowship – Society in Science
  • Wellcome Trust (grant.203783/Z/16/Z, 206298/Z/17/Z)
  • Instituto de Salud Carlos III (COV0020/00140)
  • South African Medical Research Council
  • Fast Grants (2236)
  • Wellcome Trust and Royal Society Sir Henry Dale Fellowship (204311/Z/16/Z)
  • EU Grant (874850 MOOD)
  • National Institute of Health Research
  • Deutsche Forschungsgemeinschaft (SFB900, EXC2155 RESIST)
  • UK Research & Innovation
  • Wellcome Trust (206298)
  • Department of Science and Innovation (DSI) of South Africa
  • Genome Research Limited
  • Oxford Martin School
  • BlueDot
  • Canadian Institutes of Health Research, COVID-19 Rapid Research Funding Opportunity (02179-000)
  • Biotechnology and Biological Sciences Research Council (BB/M010996/1)
  • Medical Research Council-São Paulo Research Foundation CADDE partnership award (MR/S0195/1,FAPESP 18/14389-0)

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