Human Andrology

Journal Information
ISSN / EISSN : 2090-6048 / 2090-6056
Current Publisher: Zagazig University Medical Journal (10.21608)
Total articles ≅ 44
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SHERPA/ROMEO
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Human Andrology, Volume 8, pp 91-104; doi:10.21608/ha.2019.11345.1040

Abstract:
Introduction: Introduction of the oral phosphodiesterase isoenzyme-5 inhibitors (PDE5-Is) has revolutionized sexual medicine by affording effective treatment for erectile dysfunction. PDE5 hydrolyses cyclic GMP specifically to 5′-GMP. Since its launching, PDE5-Is have stimulated scientific interest for their impending benefits in various implications for the welfare of the human beings. Aim: To highlight the possible potential implications of PDE5-Is in women.Participants and methods: A systematic review was carried out till June 2017 based on a search of concerned articles in Medline, medical subject heading databases, Scopus, The Cochrane Library, Embase, and CINAHL databases without language restriction. Keywords used to assess that outcome and concerned associations were PDE5 inhibitors, sildenafil, tadalafil, vardenafil, avanafil, women, and females.Main outcome measures: Different implications for PDE5-Is in women.Results: Oral PDE5-Is have beneficial medical implications in women. Sexual implications include female sexual dysfunction, female sexual arousal disorder, antidepressant-associated sexual dysfunction, and affected relationship. Gynecological implications include endometrial thickness, abortion, preeclampsia, fetal growth restriction, clitoral engorgement, primary dysmenorrhea, uterine blood flow, oligohydramnios, poor ovarian response, ovarian ischemia/reperfusion, and uterine contractility. Urological implications include overactive bladder and interstitial cystitis, whereas dermatological implications include systemic sclerosis and cellulite. In addition, PDE5-Is proved to be beneficial in pulmonary arterial hypertension, coronary dysfunction, esophageal motility, and some metabolic effects.Conclusion: Oral PDE5-Is are an eye-catching therapeutic class of agents with beneficial effects for women, which could be potentially applied after well-designed clinical trials.
Hanan M.A. Saleh, Ahmed Abdelfattah Afify, Walid Abdelhady Ahmed, Maged Daruish
Human Andrology, Volume 8, pp 111-114; doi:10.21608/ha.2019.6681.1037

The publisher has not yet granted permission to display this abstract.
Naglaa Agamia, Abeer S. El Hadidy, Amr M. El Abd, Asmaa H. El-Atawy, Ali F. El-Areny
Human Andrology, Volume 9, pp 99-107; doi:10.21608/ha.2020.26554.1058

The publisher has not yet granted permission to display this abstract.
Kamal Abd El-Hafez, Ehab Fawzy, Emad Kamal, Sahar Hassan, Mohammed Zakaraia, Rofaida R. Shehata
Human Andrology, Volume 8, pp 106-109; doi:10.21608/ha.2019.4844.1033

Abstract:
Purpose: To evaluate the effect of chronic hepatitis B infection on semen parameters and reproductive hormones in Egyptians. Patients and methods: In this study, 104 males were included. They were classified into two groups: 73 patients with chronic hepatitis B without liver cirrhosis (group 1) and 31 healthy volunteers (group 2). Semen samples were analyzed using a computer-aided semen analyzer. Serum levels of follicle-stimulating hormone, luteinizing hormone, total testosterone, free testosterone, estradiol, prolactin, and sex hormone-binding globulin were measured by enzyme-linked immunosorbent assay. PCR was also evaluated. Liver condition was evaluated by liver function tests and abdominal sonography. Results: Semen parameters were affected in patients. There was a significant negative correlation between semen parameters (sperm count, motility, and morphology) and level of viremia. Moreover, a significant negative correlation was detected between level of viremia and serum levels of free testosterone and follicle-stimulating hormone. However, a positive correlation was noted between level of viremia and serum levels of prolactin and estradiol.Conclusion: Hepatitis B virus may have profound implications on male fertility potential.
Sherine Abd Elrahman, Ayman Zeid, MonaEl Awady
Human Andrology, Volume 9, pp 92-98; doi:10.21608/ha.2020.24779.1056

Emad Kamal, Ahmed Abdel-Mageed, Doaa A. Mahdy, Tarek A. Rageh, Aya Y. Badran
Human Andrology, Volume 9, pp 85-91; doi:10.21608/ha.2020.24179.1055

The publisher has not yet granted permission to display this abstract.
Mohamed Ahmed Abd El Salam, Nada El Sayed Selim
Published: 1 September 2019
Human Andrology, Volume 9, pp 65-70; doi:10.21608/ha.2020.21245.1052

The publisher has not yet granted permission to display this abstract.
Essam Nada, Moustafa El-Taieb, Hassan Ibrahim
Published: 1 September 2019
Human Andrology, Volume 8, pp 87-90; doi:10.21608/ha.2018.4085.1029

Mahmoud Abd El-Mawla, Abdalla Kandil, Ahmed A. Hashim, Al-Sayed Zidan
Published: 1 September 2019
Human Andrology, Volume 8, pp 69-75; doi:10.21608/ha.2018.4550.1032

Amr ElAhwany
Published: 1 September 2019
Human Andrology, Volume 8, pp 82-86; doi:10.21608/ha.2018.6103.1036

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