Clinica Chimica Acta

Journal Information
ISSN / EISSN : 00098981 / 18733492
Current Publisher: Elsevier BV (10.1016)
Total articles ≅ 23,593
Google Scholar h5-index: 51
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Latest articles in this journal

Hirotaka Ezaki, Tomokazu Matsuura, Makoto Ayaori, Sae Ochi, Yoshihiro Mezaki, Takahiro Masaki, Masanori Taniwaki, Takayuki Miyake, Masami Sakurada, Katsunori Ikewaki
Published: 10 October 2019
Clinica Chimica Acta; doi:10.1016/j.cca.2019.09.014

The publisher has not yet granted permission to display this abstract.
Seiji Kobayashi, Hoichi Amano, Hiroyuki Terawaki, Yoshindo Kawaguchi, Takashi Yokoo
Published: 5 October 2019
Clinica Chimica Acta; doi:10.1016/j.cca.2019.09.012

Abstract:Presepsin is a useful biomarker to diagnose sepsis. However, the correlation between plasma presepsin concentrations and kidney function in the elderly with chronic kidney disease (CKD) remains to be elucidated. We determined whether plasma presepsin concentrations were influenced by kidney function decline in the elderly. One hundred seventy outpatients with CKD aged ≥65 y were enrolled. Plasma presepsin concentrations were measured using immunoassay analysis. The relationship between plasma presepsin concentration and kidney function was assessed. The median age of patients of this cohort was 778 (72-85) y and the mean estimated glomerular filtration rate was 51.8 ± 28.1 ml/min/1.73m2. Plasma presepsin concentrations in those with CKD G4-G5 (362 pg/ml [273-553]) were significantly higher than in those with CKD G1-G2 (111 pg/ml [91-113]) and CKD G3 (145 pg/ml [124-205]) (p<0.001, p<0.001, respectively). A high correlation between plasma presepsin concentrations and kidney function was observed (R2=0.733, p<0.001). Even after adjusting for confounders, plasma presepsin concentrations were independently associated with kidney function. Increases in plasma presepsin concentrations were exponentially correlated to kidney function decline in the elderly with CKD.
Xiao Chen, Xiaoqing Zhang, Biao Xu, Yue Cui, Yifan He, Ting Yang, Yong Shao, Min Ding
Published: 1 October 2019
Clinica Chimica Acta, Volume 497, pp 67-75; doi:10.1016/j.cca.2019.07.002

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Catharina Van Der Heijden, Laurence Roosens, Hugo Cluckers, Amaryllis H. Van Craenenbroeck, Bart Peeters
Published: 1 October 2019
Clinica Chimica Acta, Volume 497, pp 13-19; doi:10.1016/j.cca.2019.06.025

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Leonard T. Nguyen, Maggie Guo, Brenda Hemmelgarn, Hude Quan, Fiona Clement, Tolulope Sajobi, Roger Thomas, Tanvir C. Turin, Christopher Naugler
Published: 1 October 2019
Clinica Chimica Acta, Volume 497, pp 1-5; doi:10.1016/j.cca.2019.06.017

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Laura Sciacovelli, Giuseppe Lippi, Zorica Sumarac, Isabel Garcia Del Pino Castro, Agnes Ivanov, Vincent De Guire, Cihan Coskun, Ada Aita, Andrea Padoan, Mario Plebani
Published: 1 October 2019
Clinica Chimica Acta, Volume 497, pp 35-40; doi:10.1016/j.cca.2019.07.007

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Zu-Yong Zhang, Jun Li, Qi Ye, Yong Dong, Guang-Ming Bao, You-Kui Shen, Jian-Feng Weng, Li-Feng Luo, Meng Cen
Published: 1 October 2019
Clinica Chimica Acta, Volume 497, pp 6-12; doi:10.1016/j.cca.2019.07.008

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Yuanshi Zhou, Shuwan Xu, Haoming Xia, Zewei Gao, Rongju Huang, Enyu Tang, Xingming Jiang
Published: 1 October 2019
Clinica Chimica Acta, Volume 497, pp 20-26; doi:10.1016/j.cca.2019.07.004

Hiroaki Ishida, Meizi Jiang, Hiroyuki Ebinuma, Nobuyuki Hiruta, Wolfgang J. Schneider, Toshihiko Kinoshita, Hideaki Bujo
Published: 1 October 2019
Clinica Chimica Acta, Volume 497, pp 172-177; doi:10.1016/j.cca.2019.07.001

The publisher has not yet granted permission to display this abstract.
Jeremy Roy, Daniel Saucier, Colleen O'connell, Pier Jr Morin, Morin Pier Jr
Published: 1 October 2019
Clinica Chimica Acta, Volume 497, pp 27-34; doi:10.1016/j.cca.2019.07.012