Journal of Virology

Journal Information
ISSN / EISSN : 0022538X / 10985514
Current Publisher: American Society for Microbiology (10.1128)
Total articles ≅ 26,684
Google Scholar h5-index: 84
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Latest articles in this journal

Erika G. Marques De Menezes, Karen Jang, Ashley F. George, Mette Nyegaard, Jason Neidleman, Heather C. Inglis, Ali Danesh, Xutao Deng, Amirali Afshari, Young H. Kim, et al.
Journal of Virology; doi:10.1128/jvi.00525-20

The publisher has not yet granted permission to display this abstract.
Aleksandra Milewska, Anna Kula-Pacurar, Jakub Wadas, Agnieszka Suder, Artur Szczepanski, Agnieszka Dabrowska, Katarzyna Owczarek, Alessandro Marcello, Marek Ochman, Tomasz Stacel, et al.
Journal of Virology; doi:10.1128/jvi.00957-20

Abstract:
Currently, there are four seasonal coronaviruses associated with relatively mild respiratory tract disease in humans. However, there are also a plethora of animal coronaviruses, which have the potential to cross the species border. This regularly results in the emergence of new viruses in humans. In 2002 SARS-CoV emerged, to rapidly disappear in May 2003. In 2012 MERS-CoV was identified as a possible threat to humans, but its pandemic potential so far is minimal, as the human-to-human transmission is ineffective. The end of 2019 brought us information about the SARS-CoV-2 emergence, and the virus rapidly spread in 2020 causing an unprecedented pandemic. At present, the studies on the virus are carried out using a surrogate system based on the immortalized simian Vero E6 cell line. This model is convenient for diagnostics, but it has serious limitations and does not allow for the understanding of virus biology and evolution. Here we show that fully differentiated human airway epithelium cultures constitute an excellent model to study the infection with the novel human coronavirus SARS-CoV-2. We observed an efficient replication of the virus in the tissue, with the maximal replication at 2 days post-infection. The virus replicated in ciliated cells and was released apically. IMPORTANCE SARS-CoV-2 emerged by the end of 2019 to rapidly spread in 2020. At present, it is of utmost importance to understand the virus biology and to rapidly assess the potential of existing drugs and develop new active compounds. While some animal models for such studies are under development, most of the research is carried out in the Vero E6 cells. Here, we propose fully differentiated human airway epithelium cultures as a model for studies on the SARS-CoV-2.
Zhao-Xi Wang, Shu-Bo Liu, Hong-Xin Guan, Long-Feng Lu, Jia-Gang Tu, Songying Ouyang, Yong-An Zhang
Journal of Virology; doi:10.1128/jvi.00855-20

The publisher has not yet granted permission to display this abstract.
Yanqun Wang, Jing Sun, Xiaobo Li, Airu Zhu, Wenda Guan, De-Qiang Sun, Mian Gan, Xuefeng Niu, Jun Dai, Lu Zhang, et al.
Journal of Virology; doi:10.1128/jvi.00861-20

The publisher has not yet granted permission to display this abstract.
Sara Gianella, Antoine Chaillon, Tae-Wook Chun, Michael C. Sneller, Caroline Ignacio, Milenka V. Vargas-Meneses, Gemma Caballero, Ronald J. Ellis, Colin Kovacs, Erika Benko, et al.
Journal of Virology; doi:10.1128/jvi.00415-20

The publisher has not yet granted permission to display this abstract.
Esteban Soto, Alvin Camus, Susan Yun, Tomofumi Kurobe, John H. Leary, Thomas G. Rosser, Jennifer A. Dill-Okubo, Akinyi Carol Nyaoke, Mark Adkison, Allan Renger, et al.
Journal of Virology; doi:10.1128/jvi.00337-20

The publisher has not yet granted permission to display this abstract.
Huanyu Zhang, Wenhua Kuang, Cheng Chen, Yu Shang, Xiaoyan Ma, Fei Deng, Hualin Wang, Manli Wang, Zhihong Hu
Journal of Virology; doi:10.1128/jvi.00615-20

The publisher has not yet granted permission to display this abstract.
Yi-Ting Lai, Yih-Mei Liou, Fu Hsin, Helene Minyi Liu
Journal of Virology; doi:10.1128/jvi.00312-20

The publisher has not yet granted permission to display this abstract.
Journal of Virology, Volume 94; doi:10.1128/jvi.masthead.94-11

Abstract:
Rozanne M. Sandri-Goldin University of California, Irvine Lawrence Banks, Editor (2020) International Centre for Genetic Engineering and Biotechnology Carolyn Coyne, Minireview Editor (2020) University of Pittsburgh School of Medicine Rebecca Ellis Dutch, Editor (2022) University of
Carolina Garrido, Maria Abad-Fernandez, Marina Tuyishime, Justin J. Pollara, Guido Ferrari, Natalia Soriano-Sarabia, David M. Margolis
Journal of Virology, Volume 94; doi:10.1128/jvi.00223-20

Abstract:
Volume 92, no. 12, e00235-18, 2018, [https://doi.org/10.1128/JVI.00235-18][1]. Page 11, Acknowledgments, paragraph 2: A grant was inadvertently omitted. Line 7 should read as follows: “for AIDS Research, 5T32 AI007392-30 to Duke University, …” [1]: /lookup/doi/10.1128/JVI.00235-18
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