Microbiology and Molecular Biology Reviews

Journal Information
ISSN / EISSN : 1092-2172 / 1098-5557
Published by: American Society for Microbiology (10.1128)
Total articles ≅ 920
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Latest articles in this journal

Máté Virágh, Zsolt Merényi, Árpád Csernetics, Csenge Földi, Neha Sahu, Xiao-Bin Liu, ,
Microbiology and Molecular Biology Reviews; https://doi.org/10.1128/mmbr.00019-21

The development of sexual fruiting bodies is one of the most complex morphogenetic processes in fungi. Mycologists have long been fascinated by the morphological and developmental diversity of fruiting bodies; however, evolutionary developmental biology of fungi still lags significantly behind that of animals or plants.
Microbiology and Molecular Biology Reviews; https://doi.org/10.1128/mmbr.00104-21

In his 2001 article, “Translation: in retrospect and prospect,” the late Carl Woese made a prescient observation that “our current view of translation be reformulated to become an all-embracing perspective about which 21st century Biology can develop” (RNA 7:1055–1067, 2001, https://doi:10.1017/s1355838201010615 ). The quest to decipher the origins of life and the road to the genetic code are both inextricably linked with the history of the ribosome. After over 60 years of research, significant progress in our understanding of how ribosomes work has been made.
Sarah Zanders,
Microbiology and Molecular Biology Reviews; https://doi.org/10.1128/mmbr.00016-21

In this review, we examine the fungal spore killers. These are meiotic drive elements that cheat during sexual reproduction to increase their transmission into the next generation.
, Sébastien Causse, Valentin Baverel, Laurence Dubrez, Natalia Borges-Bonan, Oleg Demidov, Carmen Garrido
Microbiology and Molecular Biology Reviews; https://doi.org/10.1128/mmbr.00035-21

Viruses are intracellular parasites that subvert the functions of their host cells to accomplish their infection cycle. The endoplasmic reticulum (ER)-residing chaperone proteins are central for the achievement of different steps of the viral cycle, from entry and replication to assembly and exit. The most abundant ER chaperones are GRP78 (78-kDa glucose-regulated protein), GRP94 (94-kDa glucose-regulated protein), the carbohydrate or lectin-like chaperones calnexin (CNX) and calreticulin (CRT), the protein disulfide isomerases (PDIs) and the DNAJ chaperones.
Erin F. Boulanger, Anice Sabag-Daigle, Pankajavalli Thirugnanasambantham, Venkat Gopalan,
Microbiology and Molecular Biology Reviews; https://doi.org/10.1128/mmbr.00123-21

Accumulation of phosphorylated intermediates during cellular metabolism can have wide-ranging toxic effects on many organisms, including humans and the pathogens that infect them. These toxicities can be induced by feeding an upstream metabolite (a sugar, for instance) while simultaneously blocking the appropriate metabolic pathway with either a mutation or an enzyme inhibitor.
Microbiology and Molecular Biology Reviews; https://doi.org/10.1128/mmbr.00020-21

Sexual development in filamentous fungi is a complex process that relies on the precise control of and interaction between a variety of genetic networks and pathways. The mating-type ( MAT ) genes are the master regulators of this process and typically act as transcription factors, which control the expression of genes involved all stages of the sexual cycle.
Kam Pou Ha,
Microbiology and Molecular Biology Reviews; https://doi.org/10.1128/mmbr.00091-21

Staphylococcus aureus is a common cause of both superficial and invasive infections of humans and animals. Despite a potent host response and apparently appropriate antibiotic therapy, staphylococcal infections frequently become chronic or recurrent, demonstrating a remarkable ability of S. aureus to withstand the hostile host environment.
Microbiology and Molecular Biology Reviews; https://doi.org/10.1128/mmbr.00193-20

Originally, viruses were defined as miniscule infectious agents that passed through filters that retain even the smallest cells. Subsequently, viruses were considered obligate intracellular parasites whose reproduction depends on their cellular hosts for energy supply and molecular building blocks.
Microbiology and Molecular Biology Reviews, Volume 85; https://doi.org/10.1128/mmbr.00176-20

The PhoP/PhoQ two-component system governs virulence, Mg 2+ homeostasis, and resistance to a variety of antimicrobial agents, including acidic pH and cationic antimicrobial peptides, in several Gram-negative bacterial species. Best understood in Salmonella enterica serovar Typhimurium, the PhoP/PhoQ system consists of the sensor PhoQ and the transcriptional regulator PhoP.
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