Journal of Hypertension

Journal Information
ISSN / EISSN : 0263-6352 / 1473-5598
Current Publisher: Ovid Technologies (Wolters Kluwer Health) (10.1097)
Former Publisher:
Total articles ≅ 31,251
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, Pavel Goldstein, Keren Doenyas, Hadas Okon-Singer
Journal of Hypertension; doi:10.1097/hjh.0000000000002892

Abstract:
Background: Essential hypertension is an important risk factor for cerebrovascular diseases and a major cause of premature death in industrialized societies. A predisposing factor for essential hypertension is prehypertension: blood pressure (BP) values at rest that are at the higher end of the normal range. Abnormally enhanced cardiovascular responses to motor and emotional tasks have been found as predictors of essential hypertension. Yet, knowledge regarding the BP reaction to aversive stimuli and motor reaction in prehypertension is limited. Methods: We compared the reaction to aversive and neutral stimuli inducing an emotional response (experiment 1) and to the isometric handgrip exercise (IHE) inducing a motor response (experiment 2), between prehypertensive and normotensive controls. BP reactions were measured and analyzed in a continuous fashion, in contrast to previous studies that averaged BP responses across blocks. We applied a multilevel B-spline model, a continuous analysis that enabled a better understanding of the BP time course and the detection of subtle differences between groups. Results: In both tasks, we found that prehypertensive individuals showed enhanced DBP reactions compared with normotensive controls; prehypertensive individuals exhibited lower BP responses to aversive pictures and higher BP responses to the IHE. These results are in line with previous studies with healthy or hypertensive participants and suggest abnormalities already in the prehypertensive stage. Conclusion: Considering the high frequency and health risks related to prehypertension, understanding the autonomic reactions to emotional and motor stimuli in this population is of clinical and theoretical importance and could serve as a behavioural marker to identify at-risk groups.
Long Zhang, Jianping Li, Nanfang Li, Ningling Sun, Liangdi Xie, Qinghua Han, Yong Li, Xin Zheng Lu, Pengfei Sun, Yuxi Li, et al.
Journal of Hypertension; doi:10.1097/hjh.0000000000002891

Abstract:
Background: Secondary hypertension has emerged as a major public health problem in China. Early diagnosis and treatment can significantly improve the clinical outcomes. However, data on the current cause composition in China are seldom reported. Objective: To describe the trends in cause-related comorbidities in hospitalized patients with secondary hypertension in China from 2013 to 2016. Methods: This was a retrospective analysis based on the national Hospital Quality Monitoring System (HQMS) database, which collects information from the front pages of in-hospital medical records. Hospitalized patients with secondary hypertension from 746 tertiary hospitals that consistently uploaded data to the HQMS from 2013 to 2016 were enrolled. All diagnoses were identified using International Classification of Diseases version 10 (ICD-10) diagnostic codes. Descriptive analyses were used to determine the proportions of secondary hypertension causes and changing trends over 4 years. Result: The study collected data on 402 371 hospitalized patients with secondary hypertension from the HQMS during 2013–2016. Secondary hypertension caused by renal parenchymal disease ranked first and accounted for more than 50%. Obstructive sleep apnea syndrome (OSAS) followed closely with a rate of approximately 25%. Primary aldosteronism presented the highest proportion among all causes of endocrine hypertension. Regarding longitudinal changes over time, the rates of renal hypertension showed a significant downward trend from 2013 to 2016 (P < 0.001). In contrast, OSAS, endocrine hypertension, renal vascular disease, and aorta diseases maintained a significant upward trend from 2013 to 2016 (P < 0.001). The rates of these diseases in women with common secondary hypertension was higher than that of men, except in patients with OSAS (P < 0.001). In addition, renal parenchymal diseases and renal vascular diseases gradually decreased with age, whereas OSAS and aortic diseases gradually increased with age. The proportion of endocrine hypertension in the middle-aged group was higher than the other two age groups. Conclusion: The study provides important information on the changing trends of cause rate of secondary hypertension modified by age and sex in China during 2013–2016. Renal parenchymal disease is still the most common cause of secondary hypertension with a decreasing trend, followed by OSAS with an increasing trend.
, Analise Doney, Michael E. Bowen, Christopher Menzies, William T. Gheen, Deepa Bhat, Jason Fish, Sarah E. Barlow, Celette S. Skinner, Christoph U. Lehmann
Journal of Hypertension; doi:10.1097/hjh.0000000000002869

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Wei-Guo Fan, Wen-Ying Wang, Ya-Xing Meng, James E. Sharman, Gianfranco Parati, Norm R.C. Campbell, Hai Su
Journal of Hypertension; doi:10.1097/hjh.0000000000002810

The publisher has not yet granted permission to display this abstract.
, Priyanka Raju, Sumaiya Islam, Joel James, Pooja Polamarasetti
Journal of Hypertension, Volume 39, pp 1044-1045; doi:10.1097/hjh.0000000000002780

, Giorgio Soardo, Cristiana Catena
Journal of Hypertension, Volume 39, pp 864-866; doi:10.1097/hjh.0000000000002750

Valérie Tikhonoff,
Journal of Hypertension, Volume 39, pp 861-863; doi:10.1097/hjh.0000000000002782

, Pierre Boutouyrie
Journal of Hypertension, Volume 39, pp 1046-1047; doi:10.1097/hjh.0000000000002789

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