Journal of Medical and Health Studies

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EISSN : 2710-1452
Total articles ≅ 42
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, Rian Adi Pamungkas, Yudianto Budi Saroyo
Journal of Medical and Health Studies, Volume 3, pp 01-06; https://doi.org/10.32996/jmhs.2022.3.3.1

Abstract:
Imperforated hymen is a rare presentation in peripubertal girls. Imperforate hymen is the most common obstructive congenital abnormality of the female genital tract. Despite being the most common malformation in the female genital system, imperforate hymen is uncommon. It often emerges at puberty; however, prenatal, infant and adolescent cases have been reported. This study aims to report a case of 12 years girl present with cyclical abdominal pain, backache, and primary amenorrhoea with a huge mass per abdomen. This study implemented a qualitative method with a case report approach. The results of the study show imperforate hymen patients need to be treated by surgical hymenotomy.
Fasihah Irfani Fitri, Netty Delvrita Lubis, , Aida Fithrie
Journal of Medical and Health Studies, Volume 3, pp 14-20; https://doi.org/10.32996/jmhs.2022.3.2.3

Abstract:
Response assessment in neuro-oncology (RANO) criteria was established to improve the assessment of tumor response and provide guidance on the assessment of response and endpoints in neuro-oncology clinical trials. Neurologic assessment in neuro-oncology (NANO) scale is an instrument used for assessing neurological function objectively and practical in intracranial tumor patients. This study aimed to determine the association between RANO criteria with clinical outcome measured by NANO scale in intracranial tumors patients. There were 36 intracranial tumor patients that were studied in Haji Adam Malik General Hospital Medan. The RANO criteria were obtained by comparing the size of the enhanced lesion using Computed Tomography (CT) scan within an interval of a minimum of four weeks of treatment. NANO scale is a quantifiable evaluation of nine relevant neurologic domains based on examination. The NANO scale included gait, strength, ataxia, sensation, visual fields, facial strength, language, level of consciousness, and behavior as assessed domains from the medical record. We analyzed the correlation between the RANO criteria and NANO scale score using the Spearman correlation test. There were 19 males and 17 females. The mean age was 45.22±9.68 years. There were 20 patients (55.6%) with meningioma, 11 patients (30.6%) with glioma, 3 patients (8.3%) with brain metastase, and 2 patients (5.6%) with craniopharyngioma. The mean NANO scale scores for stable and progressive RANO criteria were 4.29±2.02 and 7.88±2.99, respectively. There was a significant correlation between RANO criteria and NANO scale score in patients with intracranial tumor (r = 0.468; p = 0.004). Patients with stable RANO had lower NANO scale scores indicating better response to treatment and clinical outcome.
, I Ketut Alit Utamayasa, Mahrus A. Rahman, Teddy Ontoseno
Journal of Medical and Health Studies, Volume 3, pp 21-25; https://doi.org/10.32996/jmhs.2022.3.2.4

Abstract:
Coronary artery aneurysms (CAA) are common in children with Kawasaki disease (KD) who have delayed diagnosis. This can increase the high cardiovascular burden and cause acquired heart defects in adulthood. This study aims to investigate the risk factors for CAA in children with KD. An observational retrospective case-control study was carried out in Surabaya Tertiary Hospital. We collected the medical records in the child care installation, Pediatrics ward, from 2016 to 2019. The research participants were pediatric patients who were treated with KD. The exclusion criteria were incomplete medical record data regarding the risk factors studied. The risk factors studied included age, sex, duration of fever, haemoglobin, leukocytes levels, platelets levels, C-reactive protein (CRP), and albumin levels. Twenty-eight medical records of children with KD were collected in this study; only 17 eligible patients were observed. The confirmed CAA was found in 8 patients, while 9 patients were non-CAA aged ranging from 3-124 months. Almost 60% of patients had fever duration > 7 days, and 47.1% of patients had hemoglobin <10 g/dL. Platelets were the only risk factor that had a significant correlation for developing CAA in children with KD, with a p-value of 0.015 at a 95% confidence interval (CI), odds ratio (OR) of 24 (1.785 – 336.227). Almost half of KD patients in this study were at risk for developing CAA; platelet value was a risk factor that we could consider in the administration of aspirin and IVIG therapy, providing the follow-up results and evaluating aneurysm progression or regression after IVIG administration is needed to prevent poor long-term outcomes.
, Che-Marie Lee Kin, Lutchman Kevin
Journal of Medical and Health Studies, Volume 3, pp 26-36; https://doi.org/10.32996/jmhs.2022.3.2.5

Abstract:
Retinopathy of Prematurity (ROP) is a disease of immature retinal tissue that is strongly associated with prematurity, low birth weight, and prolonged oxygen exposure. The purpose of this review is to evaluate published literature to determine which factors can be linked to the development of ROP, which factors are protective against ROP, and which factors are still unclear. It also sought to review the major oxygenation trials in premature infants to establish the recommended oxygen saturation targets in premature babies and what criteria are useful in evaluating infants for ROP. Databases (PubMed, Medline, PubMed Central, and Google Scholar) were used to obtain relevant literary articles. Key findings suggested that major risk factors for ROP were prematurity, low birth weight, and prolonged oxygen exposure. Evidence suggests that maternal diabetes, maternal smoking, prolonged rupture of membranes, lack of antenatal steroids, ethnicity, multiple births, low Apgar scores, and sepsis are risk factors for the development of ROP. Evidence suggests that maternal hypertensive disorders, mode of birth, and chorioamionitis are not associated with ROP. Recommendations of oxygen saturations in the neonate include targets of 90-95% and 90-94%. Screening for ROP is dependent on birth weight, gestational age, and risk factors, with recommendations varying according to pediatric societies.
Mohammad Saleh Ali, Mohammad Abd Al-Rahman,
Journal of Medical and Health Studies, Volume 3, pp 07-13; https://doi.org/10.32996/jmhs.2022.3.2.2

Abstract:
The primary goal is to identify the genuine incidence of peri-surgical complications associated with anterior cervical spine surgery in a low-income country. The secondary goal is to identify any risk factors predisposed to these complications; Especially dysphagia, as it is the most common perioperative complication, and to clarify the prognosis of these complications, as well as their proper management. This is a retrospective case-control study, including 109 patients who underwent anterior cervical spine intervention from the right side in Tishreen University Hospital in Lattakia, Syria, during the period between 1-1-2018 and 15-12-2021. Data was collected regarding gender, age, diagnosis (radiculopathy or myelopathy), surgical procedure, number of levels, plate addition, smoking, diabetes mellitus, and peri-surgical complications occurred during surgery proceeding to the next 14 days of follow-up. Male: female ratio was (1.4:1), 30.3% of cases were from a grouping (41-50) years of age. Myelopathy consists 56% of cases, anterior cervical discectomy and fusion (ACDF) consist of 47.7% of procedures. Intervention at one level represented the highest percentage at 52% of cases. The peri-surgical complication rate was 12.8%; divided into dysphagia 6.4%, recurrent laryngeal nerve (RLN) injury, superficial infection 1.8% each, dural tear, compressive hematoma, and neurological deterioration 0.9% each. Plate addition, 3 or more levels of intervention, and (ACDF+P) or (ACCF) surgery are all determined to be risk factors for the development of perioperative dysphagia. The majority of peri-surgical complications of anterior cervical spine surgery are minor and can be managed conservatively with a good prognosis. Early recognition of these complications with appropriate management is of paramount importance for improving the outcomes. Plate addition, 3 or more levels of intervention, and (ACDF+P) or (ACCF) surgery are all determined to be risk factors for the development of perioperative dysphagia.
Mina Guirgis, Akash Perera, Jessica Sciarretta, Sanjeeva Kariyawasam, Matthew Henderson
Journal of Medical and Health Studies, Volume 3, pp 01-06; https://doi.org/10.32996/jmhs.2022.3.2.1

Abstract:
Hiatus hernia repair is a commonly performed gastrointestinal surgeries performed worldwide for the treatment of gastro-oesophageal reflux. In the last two decades, there has been a widespread shift from open to laparoscopic repair and this has been proven to significantly reduce postoperative pain, an earlier discharge and a faster return to work. Importantly, there is an obvious gap in the literature regarding postoperative pain experiences and whether any analgesia adjuncts are utilised and to what effect they have on reducing pain and reducing the need for traditional analgesia such as opioids. One novel adjunct uncommonly utilised clinically but not thus far researched is diaphragmatic crural regional infiltration with long-acting local anaesthesia, aiming to dampen pain signals generated from the abdominal and thoracic dissection performed during hiatus hernia repair. This is a low risk, low effort technique performed intraoperatively by the surgeon under direct vision at the end of surgery targeting the vagal afferent nociceptive nerve fibres found in the crural fibres, a viable target for blockade by local anaesthesia. A cohort comparison study was performed at a single centre assessing the effects of crural infiltration with long-acting local anaesthesia performed routinely by one higher volume upper gastrointestinal surgeon, whose cohort is the intervention group. The primary end points assessed were postoperative pain outcomes and opioid requirements and the intervention cohort’s results were compared against that of another high volume upper gastrointestinal surgeon at the same hospital who does not perform crural infiltration. Consecutive cases were analysed from 2019-2021, comparing the two cohort groups’ primary endpoints. Crural infiltration was found to be opioid-sparing, with patients requiring 2mg less morphine each day compared to the non-interventional group. In addition, the interventional cohort experienced reduced peak pain scores compared to the non-interventional group. Increasing age was protective against postoperative pain whilst patients who had purely para-oesophageal hernias experienced more pain than other hernia types. There appear to be potential positive effects of crural anaesthesia infiltration following hiatus hernia repair, though not statistically significant in this study. As such more research into its effects as it can be an important adjunct in reducing postoperative pain.
Hadeel M. Al Shukri, Abdelaziz Dammak
Journal of Medical and Health Studies, Volume 3, pp 44-69; https://doi.org/10.32996/jmss.2022.3.2.7

Abstract:
Explosive Ordnance Risk Education Messages (EORE) is a multi-criteria decision-making problem (MCDM) based on three steps, namely, the identification of distinct evolution criteria, the significance criteria, and the variation of data. Because it makes use of a more sophisticated classification technique, the group decision method (GDM) based on weighted arithmetic mean (AM) to prioritize (EORE) messages is the proper approach. In contrast to GDM, which explicitly weights each criterion, GDM implicitly weights each alternative's criterion values. With the help of the new hybrid method weighting technique, we can overcome this theoretical difficulty by providing explicit weights for criteria generated with zero inconsistencies and combined with the new distance-based weighting method. SFS (spherical fuzzy set) is used in hybrid methods, although it can only be used to solve the ambiguity associated with the theoretical concerns outlined above.
Journal of Medical and Health Studies, Volume 3, pp 49-56; https://doi.org/10.32996/jmhs.2022.4.2.9

Abstract:
Microbiological contamination using biocide glutaraldehyde is one of the applications to maintain the integrity of pipelines and vessels in oil and gas production. PT. X’s data on the recording of occupational illness shows an incident that occurred in 2019 due to chemical mishandling. The incident resulted in an inappropriate selection of chemical gloves and caused seven cases of irritant contact dermatitis in workers who injected biocide containing glutaraldehyde. The purpose of this study is to evaluate permeation breakthrough time on three types of glove materials used in the glutaraldehyde biocide injection process. Data taken from replacement gloves for workers who carry out the glutaraldehyde injection process, technical data on three types of gloves used in production: butyl rubber with Viton® outer layer, 100% butyl rubber, and neoprene. Simulation calculated using NIOSH permeation calculator V.3.0.0. Result from technical data for butyl rubber with Viton®, butyl rubber BT >480 minutes, and ND for Neoprene. BT field used, butyl rubber with Viton®, butyl rubber 240 minutes, and neoprene 45 minutes. Based on simulation, open-loop BDT 4.6 minutes, SBT 4.83 μg/cm2/min, SSPR 661.648 μg/cm2/min, CP 1089.67, 4108.64 and 7369.79 μg/cm2; permeation rate 385.177 µg/(cm²*min). Closed-loop BDT 34.06 minutes, SBT 29.98 μg/cm2/min, SSPR 13.62 μg/cm2/min, CP 0.059, 356.73 and 1219.58 μg/cm2; permeation rate 10.597µg/(cm²*min). The use of gloves made of butyl rubber with Viton® and butyl rubber at PT. X is suitable for protecting workers to >30% glutaraldehyde, while a neoprene glove is not recommended.
Journal of Medical and Health Studies, Volume 3, pp 49-56; https://doi.org/10.32996/jmhs.2022.3.2.9

Abstract:
Microbiological contamination using biocide glutaraldehyde is one of the applications to maintain the integrity of pipelines and vessels in oil and gas production. PT. X’s data on the recording of occupational illness shows an incident that occurred in 2019 due to chemical mishandling. The incident resulted in an inappropriate selection of chemical gloves and caused seven cases of irritant contact dermatitis in workers who injected biocide containing glutaraldehyde. The purpose of this study is to evaluate permeation breakthrough time on three types of glove materials used in the glutaraldehyde biocide injection process. Data taken from replacement gloves for workers who carry out the glutaraldehyde injection process, technical data on three types of gloves used in production: butyl rubber with Viton® outer layer, 100% butyl rubber, and neoprene. Simulation calculated using NIOSH permeation calculator V.3.0.0. Result from technical data for butyl rubber with Viton®, butyl rubber BT >480 minutes, and ND for Neoprene. BT field used, butyl rubber with Viton®, butyl rubber 240 minutes, and neoprene 45 minutes. Based on simulation, open-loop BDT 4.6 minutes, SBT 4.83 μg/cm2/min, SSPR 661.648 μg/cm2/min, CP 1089.67, 4108.64 and 7369.79 μg/cm2; permeation rate 385.177 µg/(cm²*min). Closed-loop BDT 34.06 minutes, SBT 29.98 μg/cm2/min, SSPR 13.62 μg/cm2/min, CP 0.059, 356.73 and 1219.58 μg/cm2; permeation rate 10.597µg/(cm²*min). The use of gloves made of butyl rubber with Viton® and butyl rubber at PT. X is suitable for protecting workers to >30% glutaraldehyde, while a neoprene glove is not recommended.
Journal of Medical and Health Studies, Volume 3, pp 37-43; https://doi.org/10.32996/jmhs.2022.3.2.6

Abstract:
Knee osteoarthritis is one of the diseases that cause degeneration of articular cartilage, subchondral bone, and chronic joint pain and stiffness. While there is no effective treatment for inhibiting the progression of its advancement, there are various interventions for managing symptoms of this condition in its early stages and a few treatments for advanced stages. In patients with severe knee osteoarthritis, the most recommended treatment is surgery. However, this procedure is contraindicated for many patients because of their comorbidities. In this study, a new physical intervention for managing the symptoms of advanced knee osteoarthritis in patients whose surgery is not indicated has been investigated, and its results have been reported. These data demonstrate that this method seems to be effective in Pain and stiffness reduction and improves physical activity and quality of life. More studies are needed to ensure the result of this study in the future.
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