MedNEXT Journal of Medical and Health Sciences

Journal Information
EISSN : 2763-5678
Published by: Zotarelli-Filho Scientific Works (10.54448)
Total articles ≅ 140
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Júlio Leal Villela Garcia, Vanessa Rodrigues Do Prado Garcia, Sandro Marcelo de Moraes Valente
MedNEXT Journal of Medical and Health Sciences, Volume 3; https://doi.org/10.54448/mdnt22301

Abstract:
Introduction: In the context of liposculpture, cervicofacial liposuction involves the application of negative pressure through a hollow cannula in the subcutaneous plane to gently avulse fat cells and accurately sculpt unwanted fat deposits on the face and neck. Furthermore, lipo contouring provides a versatile tool in the facial surgeon's arsenal to achieve the desired facial profile. In 2020, approximately 15.5 million cosmetic procedures were performed in the United States alone. Objective: A systematic review was carried out on the main clinical results, presenting studies on the risk of bias, and the advances in facial and cervical liposculpture as an important aesthetic tool for the dental surgeon. Methods: The rules of the Systematic Review-PRISMA Platform were followed. The search was carried out from November 2021 to February 2022 in Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. Results: 64 articles were found involving liposculpture. A total of 32 articles were fully evaluated and 14 were included and developed in the present study. Considering the Cochrane tool for risk of bias, the overall assessment did not result in significant risk of bias studies. The Funnel Plot showed symmetrical behavior. Twenty-five studies did not meet the GRADE. Most patients who were involved in the studies showed improvements in facial augmentation and contouring. In patients with loss of facial volume, high-density fat transfer with the facial injection of SVF-gel resulted in significantly higher improvement scores and better patient satisfaction. Conclusion: According to the main clinical studies selected in the present study, cervicofacial liposculpture proved to be safe and effective. In patients with loss of facial volume, high-density fat transfer with a facial injection of SVF-gel resulted in significantly higher improvement scores and better patient satisfaction. Still, the results of the studies showed that the level of self-confidence and mental health-related quality of life can be significantly improved after facial lipofilling treatment.
Yasmin Gomes Lourencini, Mariana Perassa de Siqueira, Maisa Fugita Maekawa, Lívia Buqui Mazzoni, Arthur Marcelino Vilches de Almeida, Pedro Custódio D’Amico, Lucas Henrique Sartori Pereira, Talitha Tonini de Oliveira
MedNEXT Journal of Medical and Health Sciences, Volume 3; https://doi.org/10.54448/mdnt22302

Abstract:
Introduction: Leishmaniasis is a contagious disease endemic in Brazil, transmitted by a vector, and its installation and form of presentation depend on the immunological status, location, and type of transmitted protozoan. Objective: A case report of a patient with localized American tegumentary leishmaniasis. Method: Reviews of medical records, analysis of photographic records of diagnostic tests and the evolution of the treatment to which the patient was submitted and literature review were carried out. Case Report: An 85-year-old woman, with a history of a single lesion on the 4 cm right forearm, with raised borders, ulcerated and clean bottom, subcutaneous edema, local pain and heat, pruritus, bloody secretion in small amounts, and no systemic symptoms. The same did not show improvement with the use of ointments (dexamethasone, neomycin, ketoconazole) and lasted for 2 months. The diagnosis of leishmaniasis was confirmed and treatment with intralesional meglumine antimoniate was carried out, with the application of 3 injections with an interval of 15 days. Final considerations: The case reported and the studies surveyed reveal the importance of the new treatment route and show that, although the approach requires specific conditions, such as being a single lesion, it courses with fewer adverse effects, lower cost, and greater safety.
Juliana Da Silva Tauchert, Ana Carolina De Souza Francez, Joyce Bianca dos Santos Rodrigues, Patrícia Garani Fernandes
MedNEXT Journal of Medical and Health Sciences, Volume 3; https://doi.org/10.54448/mdnt22s305

Abstract:
This study highlighted that periodontal diseases in pregnant women can be one of the determinants of low birth weight. Studies were carried out to verify the existence of an association between maternal periodontal disease and low birth weight. Gestational period, where the occurrence of periodontal diseases (PD) is more likely, due to its hormonal and physiological changes. Therefore, pregnant women must be alert and take proper care, have prenatal care with their dentist, in addition to their oral care, they must be alert to the risks of low birth weight and premature births. Infections in regions of the genitourinary tract, such as PD, may be associated with the occurrence of low birth weight newborns through the same mechanisms as other maternal and preterm birth infections. The contraction of the uterus and cervical dilation, acting as a trigger for premature birth, can be caused by inflammatory stimuli, which can induce hyperirritability of the uterine smooth muscles. The infection and the resulting inflammatory process can cause damage to the placenta, thereby restricting fetal development. Throughout life, a woman goes through several phases of hormonal fluctuations that, in addition to interfering with the reproductive system, exert influence on other organs and systems, such as the periodontium, particularly in the presence of preexisting gingival inflammation induced by plaque. During pregnancy, a woman is exposed to several significant hormonal changes, as the placenta produces high amounts of estrogen and progesterone, which in turn affect the oral tissues. It was concluded that black women aged over 40 years old are more likely to have PD, having a higher risk of low development to the fetus.
Andréa Engracia Ruiz Corrêa, Maurício Onofre Gonçalves Corrêa, Lucas Ruiz Corrêa, Carolina Ruiz Corrêa, João Pedro Lopes de Oliveira, Ana Beatris Brussi, Elias Naim Kassis
MedNEXT Journal of Medical and Health Sciences, Volume 3; https://doi.org/10.54448/mdnt22s301

Abstract:
Introduction: the immediate loading implant (ILI) is considered to offer many advantages for the patient and the clinician, maintaining the height of the soft tissues and increasing the peri-implant bone density. Also, ILI is associated with reductions in patient pain, time, and material, with success rates of 95 to 100% being reported. Objective: Therefore, the objective of the present systematic review study was to analyze the clinical success of the immediate loading technique, to present the indication criteria and the follow-up of the procedures. Methods: The rules of the Systematic Review-PRISMA Platform. The research was carried out in July 2019 to August 2021, with articles published in the last ten years, and developed based on Scopus, PubMed, Science Direct, Scielo, and Google Scholar. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 114 articles were found involving the Immediate loading and single dental implants. A total of 94 articles were evaluated in full and 35 were included and evaluated in the present study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 30 studies with a high risk of bias, and 29 studies that did not meet the GRADE. The present systematic review study showed that the success rates with the ILI technique are compatible with those of the late load, as long as certain guidelines are followed that were divided into factors related to the patient, the surgical technique, the implant, the prosthesis, and to aesthetics. The high success rate is a consequence of the correct surgical and prosthetic planning, harmony between the implant system, patient, and dental surgeon. As for the region, currently, it can be said that ILI in total jaw rehabilitation is a procedure with high success rates that should and can be applied in all cases where the technique is efficient to provide adequate primary stability to the implants. Therefore, the technical improvement of the dentist becomes the main condition for this philosophy to be applied.
Lara Heléia Pulicci de Faveri, Isabella Crusciol Braga, Daíza Barbosa de Paiva, Elias Naim Kassis
MedNEXT Journal of Medical and Health Sciences, Volume 3; https://doi.org/10.54448/mdnt22s306

Abstract:
Introduction: In the last decades, the number of dental implant procedures has increased in the world, with about 1.0 million dental implants per year. When a tooth is lost in the posterior region of the maxilla, there is a natural resorption of the alveolar process. There are several surgical techniques that can be used to reconstruct the atrophic alveolar ridge. Objective: A systematic review was carried out to present the key considerations of bone regeneration and bone, cellular and molecular grafts for adequate bone formation for successful dental implants. Methods: The present study followed a systematic review model, following the rules of systematic review – PRISMA. The search strategy was performed in the PubMed, Cochrane Library, Web of Science and Scopus, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: The total of 132 articles were found. A total of 74 articles were fully evaluated and 31 were included in this study. Normal bone formation and tissue repair involve coordinated interaction between bone-forming cells and biological signals. TNF-α stimulates bone and cartilage resorption and inhibits collagen and proteoglycan synthesis. IL-1 induces the expression of a wide variety of cytokines. LIF and IL-6 are two such molecules that are known to stimulate the differentiation of mesenchymal progenitor cells into the osteoblastic lineage. The bioactivation of the dental implant surface with FRP has been described and discussed by the scientific community as a surface treatment for the stimulation and acceleration of the osseointegration process, as well as to achieve greater primary stability to the implant. The combination of FRP and Bio-Oss® has been studied with good clinical results, reducing healing time from 180 days to approximately 106 days. The use of bone grafts significantly improves the residual alveolar ridge regardless of the membrane used. Furthermore, implants placed in fresh extraction sockets with and without elevation of the mucoperiosteal flap can be successfully performed with augmentation procedures.
Maria Eduarda Lina da Silva, Mariana de Lima Cruz Marrubio, Vitor Hugo Berger Martins da Silva, Elias Naim Kassis
MedNEXT Journal of Medical and Health Sciences, Volume 3; https://doi.org/10.54448/mdnt22s307

Abstract:
Introduction: In the scenario of maxillary sinus surgery, when there is a loss of a dental element in the posterior region of the maxilla, there is natural resorption of the alveolar process and at the same time there will be pneumatization of the maxillary sinus. For this reason, the maxillary sinus floor elevation procedure should be performed. When grafting procedures are needed, our focus is often on the types of biomaterials and their bio stimulating properties, as well as on other types of bio stimulators to be used. Objective: It was to analyze the main clinical findings of maxillary sinus surgery and the use of bio stimulators through a systematic review. Methods: The present study followed a systematic review model, following the rules of systematic review – PRISMA. The search strategy was performed in the PubMed, Cochrane Library, Web of Science and Scopus, and Google Scholar databases. The present study was carried out from January to March 2022. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: After analyzing the main clinical findings on maxillary sinus surgery and the use of bio stimulators, it was concluded that bone regeneration processes using biomaterials and the main molecular and cellular constituents such as mesenchymal stem cells, cytokines, platelet-rich plasma, fibrin-rich plasma, exosomes, microRNAs, TNF-α, IL-1, LIF and IL-6 and prostaglandin E2 (PGE2) are strategic for the solution to large bone defects, leading to tissue or bone regeneration. The main filler biomaterials can be fibrin-rich plasma (FRP), Bio-Oss®. However, it is necessary to understand the chemical, physical and biological processes of both the biological material and the biological niche of the host for successful neovascularization and bone filling.
Débora Stefanini de Oliveira, Giulia Viana Alvarenga, Carla Roberta Pamplona Bossa, Ana Paula Bernardes Rosa Maluf, Leandro Moreira Tempest, Carlos Alberto Costa Neves Buchala
MedNEXT Journal of Medical and Health Sciences, Volume 3; https://doi.org/10.54448/mdnt22s302

Abstract:
Introduction: A successful placement of an intraradicular post needs a good endodontic treatment. Consideration should also be given to the possibility of its future removal. Authors have shown that approximately 10% of cases of teeth indicated for endodontic retreatment require removal of intraradicular posts. Objective: To carry out a concise systematic review to analyze the reasons for replacing intraradicular posts, the most effective and used techniques for removing the metallic post, the manufacture of the fiberglass post, and the difference between the two types of posts. Methods: The present study followed a systematic review model, following the rules of systematic review – PRISMA. The search strategy was performed in the PubMed, Cochrane Library, Web of Science and Scopus, and Google Scholar databases. Results and Conclusion: A total of 112 articles were found. A total of 56 articles were fully evaluated and 18 were included in this study. Based on the objective and results found in the present study, the review demonstrated the main advantages and disadvantages of the clinical performance of cast metal posts and fiberglass posts, as well as the reason for switching from metal to fiberglass posts. Despite the wear caused by endodontic treatment, it is important to check the remaining dentin to choose the best retainer, observing the amount of this remaining structure, as it directly influences the selection of the post. Regarding the removal of the metallic pin, wear, ultrasound, and seizure/removal with some traction device are used. The replacement of the metallic post can opt for fiberglass posts because they have a greater advantage compared to the metallic post, mainly for aesthetics, the manufacturing technique is more agile, they do not generate risks of root fracture and if, for any eventuality, it needs to be removed. to portray the channel, the technique is smooth and easy.
Sandey Bernardes da Silva Carvalho, Fábio Armstrong Nunes, Régis Manzini
MedNEXT Journal of Medical and Health Sciences, Volume 3; https://doi.org/10.54448/mdnt22s312

Abstract:
Introduction: In the context of oral cancer management, it is a multidisciplinary effort, as each patient presents physicians with a unique set of challenges whose management impacts both survival and quality of life. Oral and maxillofacial surgery remains the mainstay of treatment. Oral cancer (OC) has a high incidence and mortality and is among the 10 (ten) most common pathologies in the world, Brazil today represents alarming public health. OC awareness is low, especially in terms of knowledge of signs and symptoms. Also, self-examination is relatively fast, inexpensive, and simple to perform. The diagnostic accuracy of the oral self-examination needs to be established first before advocating it as a potential screening tool for early detection. Objective: the present study aimed to carry out a systematic review of the main clinical findings on the surgical treatment of oral cancer by dentists. Methods: The rules of the Systematic Review-PRISMA Platform. The research was carried out in December 2021 to February 2022 and developed based on Scopus, PubMed, Science Direct, Scielo, and Google Scholar. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results: A total of 243 articles were found. In total, 104 articles were fully evaluated and 25 were included and evaluated in this study. there was a positive impact of CAD/CAM mandibular reconstruction on mastication and swallowing function after surgery for locally advanced oral cancer for the first time. Therefore, neoadjuvant chemotherapy plays a potential role in mandibular preservation in oral cancers with acceptable toxicities and without compromise in survival. The low prevalence of oral self-examination was more common among the elderly, being more common to oral cancer. Thus, educational actions can influence people's self-perception of their oral condition. In this way, the studies showed that to achieve the success of the surgical treatment of oral cancer, it is necessary for the individuals themselves to expand the self-examination care, linked to the evaluation and early diagnosis of dental surgeons. Conclusion: The studies showed that to achieve the success of the surgical treatment of oral cancer, it is necessary that self-perception of oral health, one of the components of quality of life, refers to a subjective experience of the individual about their functional, social and psychological well-being.
Paolla Simões Pessoa, Brenda Lemes dos Reis, Lucas Andrade Souza, Fábio Pereira Linhares de Castro
MedNEXT Journal of Medical and Health Sciences, Volume 3; https://doi.org/10.54448/mdnt22s310

Abstract:
Introduction: In the context of root canal treatments, nickel-titanium endodontic rotary instruments fracture due to torsional overload or cyclic fatigue. Channels with bends located closer to the channel orifice and channels with double bends (S-shaped channels) have been shown to increase the risk of fatigue failure of rotating instruments. Thus, Yared was the first to report the use and effectiveness of reciprocating motions for rotary files, as he demonstrated that a single reciprocating file was sufficient to replace several files used in continuous rotation. Objective: A concise systematic review was carried out on the main results of clinical studies on the use of reciprocating files, to externalize the scientific evidence of these files to files used in continuous rotations. Methods: The present study followed the model of systematic literature review (PRISMA). The research was carried out from January 2022 to March 2022 and was developed based on Google Scholar, Scopus, PubMed, Scielo, and the Cochrane Library. The quality of scientific evidence of the studies was based on the GRADE instrument. The risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 85 articles were found. After the process of analyzing the quality of scientific evidence, 32 articles were selected. After analyzing the risk of bias, 8 recent clinical studies, from 2019 to 2022, were selected to compose this systematic review. Based on the clinical studies presented in the present study, it was evidenced that there is a significant statistical difference in the number of cycles in and out movement and wear time to failure between reciprocating and continuous rotary files. Furthermore, an endodontic treatment combining a single reciprocating file with a single cone showed similar clinical efficacy to treatment with hand file instrumentation and lateral compaction obturation. However, randomized clinical studies have shown that reciprocating instruments have less resistance to cyclic fatigue when operated in canals with curvatures in the coronal and middle thirds when compared with curvatures in the apical thirds.
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