Journal of Biomedical Research & Environmental Sciences

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EISSN : 2766-2276
Published by: SciRes Literature LLC (10.37871)
Total articles ≅ 311
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Evamaria Brigitta Kaiser, Mariya Ivancheva
Journal of Biomedical Research & Environmental Sciences, Volume 3, pp 227-235; https://doi.org/10.37871/jbres1427

Abstract:
Factors that influence learning are vitally discussed in language learning circles but are rather underexplored in the field of technology-enhanced language learning (hereafter TELL). Considering these factors shall assist with responding to the research question of how technology can enhance language learning by taking into consideration the socio-economic contexts of learners. Through a review of literature across academic fields and seven qualitative interviews with key practitioners in this area from across Europe, we address the issue of the digital divide. We discuss arising challenges for self-expression, self-determination, and autonomy in the social space of language learning due to unequal initial positions of language learners, which co-determine success. Implications for practice and policy include the awareness about these multilayered factors that influence TELL to strive for equality with regards to access to knowledge, learning materials and spaces for learners from different backgrounds.
Pawel Stefanczyk, Anna Polewczyk, Dorota Nowosielecka, Lukasz Tulecki, Maria Miszczak-Knecht, Wojciech Jachec, Andrzej Kleinrok, Katarzyna Bieganowska, Andrzej Kutarski
Journal of Biomedical Research & Environmental Sciences, Volume 3, pp 221-226; https://doi.org/10.37871/jbres1426

Abstract:
Children require often replacement of leads even several times. Repeated extraction in this group nay be challenging. We report the case of a 22-year-old man with the first pacemaker implanted in the first year of life, after Transvenous Lead Extraction procedure (TLE) and implantation of a dual-chamber pacemaker in the age of 12 years, who was admitted to the reference center for repeated TLE and to replace the entire pacing system. The presence of complete venous occlusion, lead strain and strong lead-to-lead adherence with calcified connecting tissue scar effected TLE complicity and needed utility of numerous tools and atypical technique and tricks among of them simultaneous extraction of strongly connected each one leads together via one tool showed to be crucial.
Mohammadreza Shahidipak
Journal of Biomedical Research & Environmental Sciences, Volume 3, pp 307-310; https://doi.org/10.37871/jbres1438

Abstract:
Mediterranean is the birthplace of civilizational changes in world. There is special school of medicine in east of Islamic world which was formed by transferring Iranian medical heritage from ancient university of Jondishapur and medical sciences of India, Alexandria, Greece and Egypt. Therefore, Baghdad has arisen as a combined medical school. There is same school of medicine was established in west of Islamic world by evolutionary processes of Islamic medicine during its Mediterranean life and produced independent medical schools. Medical experience schools of ancient Cairo, Tunisia, Cordoba and Sicily transferred in Qairwan. This shows that medical development in Mediterranean world of Islamic period has been an increasing development, and Islamic medicine in the Mediterranean. Despite having Iranian roots and its origin go back to Avicenna, the founder of Islamic medicine and philosophy had a higher position than each other. It has acquired its oriental type. The medical school in the Mediterranean took place with the transfer of medicine from the first house of wisdom in the Islamic world to the second house of wisdom, which was built in Qairwan by Aghlabids state. The reality of Mediterranean period of Islamic medicine and its physical role in history of world medicine played by House of Wisdom (Beit al-Hakmeh ) Qairwan in the last stages of its development has prepared the collection of Islamic medical knowledge produced in Beit al-Hikma in Baghdad for final development by combining Latin teachings. By Transfer of Roman and Byzantine; medical knowledge from the Latin world to the Islamic world, which was a major milestone in the history of world medicine in southern Europe was made in Andalusia on the Iberian Peninsula, setting the stage for the latest evolution of medicine. A vast body of medical knowledge was transferred from North Africa and Andalusia to Europe (Salerno Italy) at the beginning of the European Renaissance.
Komal Anjum, Ye Xuewei
Journal of Biomedical Research & Environmental Sciences, Volume 3, pp 246-263; https://doi.org/10.37871/jbres1430

Abstract:
Natural product search is an enduring revitalization upon the exploration of a huge already exotic potential for Secondary Metabolite (SM) production obscure in microbial genomes. Filamentous fungi genomes have an immense number of “orphan” SM gene clusters. Current evaluation indicates that only 5% of extant fungal species have been explored, thus the apparent for the disclosure of novel metabolites in fungi is extensive. In this situation, fungi burgeoning in severe environments are of special interest since they are distinguished producers of astonishing chemical structures. Genome mining strategies, more specifically epigenetic strategies are playing an important role in natural product discovery. This review has been organized and written to focus on available epigenetic approaches, targeting on DNA methyltransferase and histone deacetylase inhibitors along with reported novel secondary metabolites. To the best of our knowledge, this review article is the first attempt to incorporate the facts regarding DNA methyltransferase inhibitors and histone deacetylase inhibitors along with reported novel secondary metabolites with their recorded bioactivities.
Orefejo Bola, Avuwa Joseph Oteri, Samuel Bawa, Loveday Nkwogu, John Wagai, Adejoke Oladele, Sarah Kariya, Akinkunmi Akinbajo, Samuel Yenyi, Boubacar Dieng, et al.
Journal of Biomedical Research & Environmental Sciences, Volume 3, pp 268-276; https://doi.org/10.37871/jbres1432

Abstract:
Background: Schools based vaccination provide opportunity for the delivery of routine vaccines, using the school as the venue of delivery. During the 2017/2018 measles vaccination campaign, the school system stakeholders were systematically engaged for buy-in to vaccinate 9-59 months old children in Lagos State, Nigeria. This paper is a report of how the Lagos state school authority were engaged for the 2018 measles vaccination campaign. It also highlights the contribution of the engagement in the overall performance of the state looking at the vaccination coverage data and comparing that with the previous campaign. Method: We reported on the role of engaging the school health system in improving coverage using a descriptive mixed-method study design. The stakeholders cutting across the government, education sector, public and private schools were identified and engaged through coordination meetings, dialogues, lobby and sensitization to support vaccination in schools. We summarized the outcome of the engagement activities, analyzed the administrative, post-campaign coverage data and compared it with the 2016 measles supplemental activities coverage. Results: A total of 12,903 schools were used as venues (vaccination posts), while 22 sensitization meetings were held with school associations. About 80% of all eligible children vaccinated in the Local Government Areas (LGAs) during the 2018 Measles Vaccination Campain (MVC), received the vaccine at schools. The lowest proportion of children vaccinated at school was 45.0% in Oshodi LGA. Surulere LGA had the highest proportion of children vaccinated in schools (95.0%). Overall, Lagos state had a weighted average coverage of 93.8% for the post-campaign coverage survey. Conclusion: The implementation of the school engagement process for supplemental immunization activities contributed to achieving high vaccination coverage as most of the children aged 9-59 months were vaccinated in schools.
Khaled Ali Abu Ali
Journal of Biomedical Research & Environmental Sciences, Volume 3, pp 316-319; https://doi.org/10.37871/jbres1440

Abstract:
Background: Hepatitis B is a vaccine-preventable liver infection caused by the Hepatitis B Virus (HBV). Hepatitis B (HB) is spread when blood, semen, or other body fluids from a person infected with the virus enters the body of someone who is not infected. Aim of the study: To identify the efficacy of hepatitis B immunoglobulin with hepatitis B vaccine versus hepatitis B vaccine alone to prevent the HB vertical infection. Method: An quasi-experimental clinical trial was used, 114 new born were included in the control group and 114 newborn were included in the intervention group, both groups were given HB vaccine but the control group HB vaccine combined with hepatitis B immunoglobulin, all of the subjects were born to mother positive HBV and negative HBeAg indicating inactive HBV cases. Results: Revealed that the used regimens were effective to interrupt mother to child transmission of HBV, the geometric mean titration was higher (207.64 IU/L) among the infants were included in the control group versus (180.87 IU/L) to the infants were included in the intervention group, non-protective rate was 6.6%, relative risk 2.63. Conclusion: Hepatitis B vaccine alone is not inferior to HB vaccine combined with HBIG to prevent the infection and both regimens were effective.
Suprapto Suprapto, Yatim Lailun Nimah
Journal of Biomedical Research & Environmental Sciences, Volume 3, pp 277-282; https://doi.org/10.37871/jbres1433

Abstract:
Classification is supervised machine learning applicable to predict chemicals based on their properties. The chemical properties are derived from its structural and functional groups. Many molecular descriptors have been developed, one of which, was pharmacophore. Pharmacophore is a quantitative measure of molecules in their application as a pharmaceutical ingredient. The training datasets were 59 molecules categorized on their adsorption properties. The classification was carried out to divide the training set into their adsorption class using their pharmacophores. The prediction of enolic curcumin and its degradation product was used to verify the trueness of classification methods based on their pharmacophores. Curcumin and its degradation product were used because there were many studies carried out about curcumin and its pharmaceutical effect.
Shanti Lal Choubisa
Journal of Biomedical Research & Environmental Sciences, Volume 3, pp 264-267; https://doi.org/10.37871/jbres1431

Abstract:
Chronic fluoride intoxication in the form of fluorosis is a worldwide health problem and endemic at least in 25 countries. The principal cause of fluorosis in humans is the prolonged exposure of fluoride through drinking of fluoridated water. However, industrial fluoride emission and fluoride containing foods are also potential sources of fluoride exposures for the genesis of fluorosis. As per guidelines of the World Health Organization (WHO) fluoride content in the drinking water should not be higher than 1.5 mg/L (ppm). Above this limit of fluoride in drinking water, it becomes toxic and injurious for human health and causes diverse deformities in teeth and bones. In humans, basically three forms of fluorosis namely dental, skeletal and non-skeletal fluorosis have been recognised. The diagnosis of fluoride intoxication (fluorosis) in humans is made on the basis of history, clinical or pathognomonic signs and testing of biological samples. The current status of endemic fluorosis could be assessed by estimation of fluoride in the blood serum and urine. The presence of dental mottling and calcification of interosseous membrane on a forearm radiograph may be helpful in the diagnosis of dental and skeletal fluorosis, respectively. For the prevention of fluorosis, fluoride free drinking water and food items, diet having ample amount of nutrients, general awakening in people and collective efforts are important and highly needed. This editorial will be useful for researchers and health workers in the diagnosis and prevention of fluorosis in humans, respectively.
Rasa Uspalyte Vitkuniene
Journal of Biomedical Research & Environmental Sciences, Volume 3, pp 311-315; https://doi.org/10.37871/jbres1439

Abstract:
New engineering solutions have been developed with the aim to help the driver over the past few decades. 94 ± 2.2% of accidents are caused by a human choice or error, where the critical reason, in the crash causal chain, was assigned to the driver. Autonomous Vehicles (AV) have great potential for improving road safety. This paper provides overview of the autonomic car background, the need for infrastructure for competitive entry of autonomous cars into the urban transport market. The description of the potential of autonomous cars covers the two main most promising areas: the application of AV to public transport and AV in car sharing service.
Liviu Popa Simil
Journal of Biomedical Research & Environmental Sciences, Volume 3, pp 294-301; https://doi.org/10.37871/jbres1436

Abstract:
Planet Earth is a little one, and on one side it hosts the continents and on the opposite side is the Pacific Ocean, where the dry land represents 29%, from which 30% are deserts and 20% are mountains, while 50% is used for human activities. An integrated environment includes Earth and humans [1], as part of the Earth’s fauna, and any living creature from few nanometers up the very large ones, having in common pursue of life. The recent planetary SARS-Cov-2 pandemic [2] placed a special stress on the planet, and placed in the lime-light the dominant characteristics and moral values of humans, their incapability to identify a real threat, adapt and prevail. Due to coarse incompatibility of moral values of various nations, with real life values, many nations ended up politicizing the pandemic and having inappropriate preparedness and response, and as a consequence they recorded high losses in human lives and standard of lives. Earth registers a record high of death, of about 7 Million from which USA worth only 4% of Earth’s population contributed with an exceptionally tragic milestone of 1 Million deaths [3]. Due to inappropriate measures to stop the pandemic, the planet slipped into economic troubles as inflation and supply cycles disruption, that set a supplementary pressure to climate challenge, and for some with terrible moral values for which truth is their enemy, needed an escape goat to distract from the real economic and cultural problem and badly needed a new war, in an exacerbation of xenophobia, hypocrisy and misinformation [4]. This new calamity, has good chances of transforming into a nuclear war, where about 10,000 strikes of about 100 Mt-TNT might be applied to northern hemisphere [5]. In the present conditions COVID is embedded in the environment [6], with new variants due to pandemic as delta, O’micron and BA2, and few more, and from environment is given back to humans, and a new surge appeared in Europe with a delay of about 2 mo. from the elimination of all restrictions. This means that by April- May US will be infected again, with a new version escaping previously made vaccines. In the eventuality of a Nuclear War, ignoring the directly affected areas, the presence of heat and then cold, radioactive pollution, will trigger the gain of function of many passive, or dormant viruses, which will find a new ground of reproduction on the hoards affected by the exposure to nuclear warfare, and having handicapped immunity systems [7]. The survivors from the nuclear war will find difficult to survive to the pandemic with radiation enhanced novel viruses and functional structures.
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