Laryngo-Rhino-Otologie

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ISSN / EISSN : 0935-8943 / 1438-8685
Published by: Georg Thieme Verlag KG (10.1055)
Total articles ≅ 25,724
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, Constanze Pohlmeier, Orlando Guntinas-Lichius, Thomas Bitter
Published: 25 January 2022
Laryngo-Rhino-Otologie; https://doi.org/10.1055/a-1730-5653

Abstract:
Zusammenfassung: Einleitung Kardiale Riechreizfolgereaktionen könnten die Palette objektivierender Testmethoden zur Überprüfung des Riechvermögens erweitern. In einer Pilotstudie wurde untersucht, ob und wie durch angenehme und unangenehme Gerüche die Herzfrequenz (HR) und deren Variabilität verändert werden. Methodik 32 Gesunde mit normalem Riechvermögen atmeten nasal 7 Minuten den Duft von 4 Sniffin’ Sticks (Banane, Fisch, Knoblauch und Rose) im Wechsel mit Leer-Reizen ein. Gleichzeitig wurden das EKG registriert und offline die NN-Intervalle (Abstand der R-Zacken) und 6 Parameter der Herzfrequenzvariabilität bestimmt und mit den Werten einer Leer-Reizung mittels generalisierter Schätzgleichungen (GEE) verglichen. Zusätzlich wurden die Werte der subjektiven Einschätzung von Intensität und hedonischer Valenz der 4 Gerüche mit der Herzfrequenz korreliert. Ergebnisse Der unangenehme Fischgeruch steigerte in der ersten Reiz-Minute gering, aber signifikant die Herzfrequenz (HR). Außerdem vergrößerte er während des Dauerreizes lediglich einen Variabilitätsparameter (LF/HF) und zeigte in der ersten Reiz-Minute eine signifikante moderate Korrelation zwischen der HR und der Skalierung von Intensität bzw. der Hedonik. Die angenehmen Gerüche und der Knoblauchgeruch hatten keinen Einfluss auf die analysierten kardialen Parameter. Schlussfolgerungen Olfaktorisch ausgelöste HR-kardiale Riechreizfolgereaktionen sind es wert, als Indikator für die Intaktheit des Riechvermögens weiter untersucht zu werden. Am erfolgversprechendsten und zeit- und kostengünstigsten ist dabei wahrscheinlich eine 1-minütige Reizung mit dem unangenehmen Fischgeruch aus dem Identifikationsset der Sniffin’ Sticks bei gleichzeitiger EKG-Ableitung.
Ferhat Tek, , Thomas Verse
Published: 24 January 2022
Laryngo-Rhino-Otologie; https://doi.org/10.1055/a-1730-5789

Abstract:
Received: 02 August 2021 Accepted after revision: 30 December 2021 Publication Date: 24 January 2022 (online) © 2022. Thieme. All rights reserved. Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany
, Barbara Bastiaansen, Milan Richir, W.L. Hazen, Jurriaan Tuynman, Sjoerd G. Elias, R W.M. Schrauwen, Frank P. Vleggaar, , Philip Bos, et al.
Published: 24 January 2022
Abstract:
Risk for lymph node metastasis associated with deep submucosal invasion should be balanced against mortality and morbidity of total mesorectal excision (TME). Dissection through the submucosa (ESD), hinders radical deep resection margins, and full thickness resection (TEM/TAMIS) may influence the outcome of completion TME. Endoscopic intermuscular dissection (EID) in between the circular and longitudinal part of the muscularis propria could potentially provide an R0 resection while leaving the rectal wall intact. In this prospective cohort study, data of patients treated with EID for suspect deep submucosal invasive rectal cancer between 2018-2020 were analysed. Study outcomes were the percentages of technical success, R0 resections, curative resections, and adverse events. In total 67 cases (age 67 yrs; 73% male) were included. Median lesion size was 25 mm (IQR 20-33). Overall technical success, R0 resection, and curative resection rates were (96%; 95%CI 90-100%), 81% (95%CI 72-90%) and 45% (95%CI 33-57%). Only minor adverse events occurred in 8 patients (12%). EID for deep invasive T1 rectal cancer appears to be feasible and safe, and the high R0 resection rate creates a rectal preserving potential in 45% of patients.
Eric Tsz-Chun Poon, Grant Tomkinson, Wendy Yajun Huang, Stephen H.S. Wong
International Journal of Sports Medicine; https://doi.org/10.1055/a-1738-2072

Abstract:
Low physical fitness in adolescence is linked with increased cardiometabolic risk and early all-cause mortality. This study aimed to estimate temporal trends in the physical fitness of Hong Kong adolescents aged 12–17 years between 1998 and 2015. Physical fitness (9-min run/walk, sit-ups, push-ups, and sit-and-reach) and body size data in a total of 28,059 adolescents tested across five population-representative surveys of Hong Kong secondary school pupils, were reported. Temporal trends in means were estimated at the gender-age level by best-fitting sample-weighted linear regression, with national trends estimated by a post-stratified population-weighting procedure. Overall, there were small declines in 9-min run/walk (effect size (ES) = 0.29 (95%CI: 0.32, 0.26)) and sit-ups performance (ES = 0.24 (95%CI: 0.27, 0.21)), with negligible changes in push-ups and sit-and-reach performance. There were small concurrent increases in both mean height and body mass, with a negligible increase in sum of skinfolds. Trends in mean physical fitness and body size/ were not always uniform across the population distribution. The small declines in mean 9-min run/walk and sit-ups performance for Hong Kong adolescents are suggestive of corresponding declines in cardiorespiratory fitness and abdominal/core endurance, respectively. Increased national health promotion strategies are required to improve existing fitness trends.
Baohong Yang, Lingjian Kong, Ullah Saif, Lixia Zhao, Dan Liu, De-Liang Li, Xuezhong Shi, Xiaocan Jia, Dalal Paras, Bingrong Liu
International Journal of Sports Medicine; https://doi.org/10.1055/a-1737-6381

Abstract:
Background and study aims: To assess the efficacy and clinical outcomes of endoscopic retrograde appendicitis therapy (ERAT) versus laparoscopic appendectomy (LA) for patients with uncomplicated acute appendicitis (AA). Patients and methods: We adopted propensity score matching (1:1) to compare ERAT and LA patients with uncomplicated AA from April 2017 to March 2020. We reviewed a total of 2880 patients with suspected acute appendicitis, of whom 422 patients with uncomplicated AA met the matching criteria (ERAT, 79; LA, 343), yielding 78 pairs of patients. Results: The rate of curative treatment within one year after ERAT was 92.1%; 95% CI, [83.8% - 96.3%]. The percentage of Visual Analog Scale (VAS) ≤ 3 at six hours after treatment was 94.7%; 95% CI [87.2% - 97.9%] in the ERAT group, and significantly higher than that in the LA group 83.3%; 95% CI [73.5% - 90.0%]. Median operative/procedure time and median hospital length of stay in the ERAT group were significantly lower compared to the LA group. At one year, the median recurrence time was 50 days (IQRs, 25-127) in the ERAT group. The overall adverse event rate was 24.3%; 95% CI [14.8% - 33.9%] in the LA group and 18.4%; 95% CI [9.7% - 27.1%] in the ERAT group, with no significant difference between the two groups. Conclusions: ERAT is a technically feasible method to treat uncomplicated AA compared to LA.
, Gerlind Schneider, Randolf Riemann, Luisa Symeou, Christopher Bohr, Burkard Lippert
International Journal of Sports Medicine; https://doi.org/10.1055/a-1722-3252

Abstract:
Received: 07 January 2021 Accepted after revision: 08 December 2021 Publication Date: 12 January 2022 (online) © 2022. Thieme. All rights reserved. Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany
José-Antonio Salas-Montoro, , Cristóbal Sánchez-Muñoz, Mikel Zabala
International Journal of Sports Medicine; https://doi.org/10.1055/a-1738-0252

Abstract:
The use of near-infrared spectroscopy could be an interesting alternative to other invasive or expensive methods to estimate the second lactate threshold. Our objective was to compare the intensities of the muscle oxygen saturation breakpoint obtained with the Humon Hex and the second lactate threshold in elite cyclists. Ninety cyclists performed a maximal graded exercise test. Blood capillary lactate was obtained at the end of steps and muscle oxygenation was continuously monitored. There were no differences (p>0.05) between muscle oxygen oxygenation breakpoint and second lactate threshold neither in power nor in heart rate, nor when these values were relativized as a percentage of maximal aerobic power or maximum heart rate. There were also no differences when men and women were studied separately. Both methods showed a highly correlation in power (r=0.914), percentage of maximal aerobic power (r=0.752), heart rate (r=0.955), and percentage of maximum heart rate (r=0.903). Bland-Altman resulted in a mean difference of 0.05±0.27 W·kg–1, 0.91±4.93%, 0.63±3.25 bpm, and 0.32±1.69% for power, percentage of maximal aerobic power, heart rate and percentage of maximum heart rate respectively. These findings suggest that Humon may be a non-invasive and low-cost alternative to estimate the second lactate threshold intensity in elite cyclists.
, Ursula Deitmerg, Sophia Gantner
International Journal of Sports Medicine; https://doi.org/10.1055/a-1727-6012

Abstract:
Zusammenfassung: Die SARS-CoV-2-Pandemie bedeutet für Berufstätige im Gesundheitswesen eine besondere Belastung in mehreren Bereichen, u.a. durch das Tragen einer Mund-Nasen-Bedeckung und damit veränderter Kommunikation. In einer prospektiven Studie wurde die Belastung des Vokaltrakts und das psychisch-körperliche Wohlbefinden hier am Beispiel von Tätigen in der Altenpflege mittels Fragebogen erfasst. Methoden In 2 Altenpflegeeinrichtungen wurden die standardisierten Fragebogen Symptom-Checkliste 90 in der Kurzversion (Mini-SCL) und die Vocal Tract Discomfort Scale (VTDS) in deutscher Übersetzung eingesetzt, kombiniert mit Fragen zu Alter, Komorbidität, Stimme und bereits erfolgter SARS-CoV-2-Infektion. Ergebnis Bei einer Rückmeldung von 67 von 100 ausgeteilten Fragebogen zeigten sich bei den teilnehmenden Mitarbeitern (56 Frauen und 11 Männer, 45,2 ± 11,5 Jahre alt) erhöhte Werte für beide Fragebogen. Im Mini-SCL wiesen in der Skala Depressivität 23,8% erhöhte Werte auf, in der Skala Ängstlichkeit 49,3%, in der Skala Somatisierung 55,2% und in der Gesamtskala 44,7%. Bei 52% der Teilnehmer ergaben sich erhöhte Werte im VTDS. Zwischen dem VTDS und den Einzelskalen des Mini-SCL sowie zu Stimmbeschwerden bestand jeweils ein signifikanter Zusammenhang. Diskussion In der Altenpflege Tätige leiden während der Pandemie vermehrt unter psychischen und physischen Beschwerden. Es bestehen Zusammenhänge zwischen Missempfindungen im Vokaltrakt und Stimmsymptomen sowie dem emotionalen und körperlichen Wohlbefinden. Stimmhygienische Schulungen können bei den aktuell erhöhten kommunikativen Anforderungen hilfreich sein.
, Anna Rawa-Golebiewska, Audrey H. Calderwood, Lone D. Brix, Louise B. Grode, Edoardo Botteri, Marek Bugajski, Michal F. Kaminski, Wladyslaw Januszewicz, Hjalmar Ødegaard, et al.
International Journal of Sports Medicine; https://doi.org/10.1055/a-1734-7952

Abstract:
Background and study aims: Endoscopic screening with polypectomy reduces colorectal cancer (CRC) incidence. Incomplete polyp removal may attenuate the effect of screening. This randomized trial compared cold snare polypectomy (CSP) with hot snare polypectomy (HSP) regarding complete polyp resection. Patients and methods: We included patients ≥ 40 years at 8 hospitals in 4 countries who had at least one 4-9 mm non-pedunculated polyp detected at colonoscopy. Patients were randomized 1:1 to CSP or HSP. Biopsies from the resection margins were obtained systematically after polypectomy in both groups. We hypothesized that CSP would be non-inferior to HSP with a non-inferiority margin of 5%. Logistic regression models were fitted to identify factors explaining incomplete resection. Results: In total, 425 patients, with 608 polyps were randomized to either CSP or HSP. Of 318 polyps removed by CSP and 283 polyps removed by HSP, 34 (10.7%) and 21 (7.4%) were incompletely resected, respectively, with an adjusted risk difference of 3.2% (95% CI -1.4 – 7.8). There was no difference between the groups in terms of post-polypectomy bleeding, perforation, or abdominal pain. Independent risk factors for incomplete removal were serrated, odds ratio (OR) 3.96, (95% CI 1.63-9.66) and hyperplastic histology, OR 2.52 (95% CI 1.30-4.86)) in adjusted analyses. Conclusion: In this randomized trial, non-inferiority for cold snare polypectomy could not be demonstrated. Polyps with serrated histology are more prone to incomplete resection compared to adenomas. Cold snare polypectomy for small polyps can be used safely in routine colonoscopy practise.
, , Vitor Moreira, Francisco Miranda, Nuno Romano, Fábio Yuzo Nakamura
International Journal of Sports Medicine; https://doi.org/10.1055/a-1678-7340

Abstract:
The aim of the present study was to determine the creatine kinase reference limits for professional soccer players based on their own normal post-match response. The creatine kinase concentration was analyzed in response to official matches in 25 players throughout a 3-year period. Samples were obtained between 36–43 hours following 70 professional soccer matches and corresponded to 19.1±12.1 [range: 6–49] samples per player. Absolute reference limits were calculated as 2.5th and 97.5th percentile of the samples collected. Creatine kinase values were also represented as a percentage change from the individual’s season mean and represented by 90th, 95th and 97.5th percentiles. The absolute reference limits for creatine kinase concentration calculated as 97.5th and 2.5th percentiles were 1480 U.L−1 and 115.8 U.L−1, respectively. The percentage change from the individual’s season mean was 97.45±35.92% and players were in the 90th, 95th and 97.5th percentiles when the percentages of these differences were 50.01, 66.7, and 71.34% higher than player’s season mean response, respectively. The data allowed us to determine whether the creatine kinase response is typical or if it is indicative of a higher than normal creatine kinase elevation and could be used as a practical guide for detection of muscle overload, following professional soccer match-play. Received: 04 August 2020 Accepted: 13 October 2021 Publication Date: 09 January 2022 (online) © 2021. Thieme. All rights reserved. Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany
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