Archives of Ophthalmology

Journal Information
ISSN / EISSN : 00039950 / 15383601
Current Publisher: American Medical Association (AMA) (10.1001)
Total articles ≅ 29,561
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Ingrid U. Scott, Paul C. VanVeldhuisen, Neal L. Oden, Michael S. Ip, Amitha Domalpally, Bernard H. Doft, Michael J. Elman, Barbara A. Blodi, SCORE Study Investigator Group
Archives of Ophthalmology, Volume 130, pp 1517-24; doi:10.1001/archophthalmol.2012.2728

Abstract:To compare baseline characteristics and treatment response of participants with hemiretinal vein occlusion (HRVO) with those of participants with branch retinal vein occlusion (BRVO) or central retinal vein occlusion (CRVO) in the Standard Care vs COrticosteroid for REtinal Vein Occlusion (SCORE) Study. Eyes were randomized to standard care, 1 mg intravitreal triamcinolone acetonide, or 4 mg intravitreal triamcinolone acetonide. Standard care was observation in the SCORE-CRVO trial and grid photocoagulation in the SCORE-BRVO trial. The HRVO eyes were enrolled in the SCORE-BRVO trial. Baseline characteristics, changes in visual acuity and center point thickness, safety outcomes, and number of treatments were compared among HRVO, BRVO, and CRVO participants. At baseline, HRVO eyes were intermediate between BRVO and CRVO eyes in area of retinal thickening, area of fluorescein leakage, visual acuity, and center point thickness. No differences in visual acuity change from baseline to 1 year were noted between standard care groups for HRVO and BRVO. Within triamcinolone-treated eyes, HRVO eyes did not differ from BRVO eyes in visual acuity change, but HRVO eyes fared better than CRVO eyes. There were no differences in center point thickness change between standard care groups for HRVO and BRVO, nor were there differences across the 3 disease entities for triamcinolone-treated eyes. There were no differences in frequency of protocol treatments and adverse events. The HRVO participants were similar to BRVO and CRVO participants regarding most demographic characteristics, with fundus findings intermediate between BRVO and CRVO. In the SCORE Study, HRVO was treated as BRVO; HRVO eyes responded to treatment similarly to BRVO eyes, and there was no difference among the 3 disease entities in frequency of protocol treatments and adverse events. clinicaltrials.gov Identifier: NCT00105027.
David K Wallace, Don L Bremer, William V Good, Rae Fellows, C Gail Summers, Betty Tung, Robert J Hardy
Archives of Ophthalmology, Volume 130; doi:10.1001/archopht.130.12.1510

The publisher has not yet granted permission to display this abstract.
Carlos Gustavo De Moraes, Shaban Demirel, Stuart K Gardiner, Jeffrey M Liebmann, George A Cioffi, Robert Ritch, Mae O Gordon, Michael A Kass
Archives of Ophthalmology, Volume 130; doi:10.1001/jamaophthalmol.2013.1137

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Kaweh Mansouri, Felipe A Medeiros, Ali Tafreshi, Robert N Weinreb
Archives of Ophthalmology, Volume 130, pp 1559-1559; doi:10.1001/jamaophthalmol.2013.1350

Abstract:To examine the safety, tolerability, and reproducibility of intraocular pressure (IOP) patterns during repeated continuous 24-hour IOP monitoring with a contact lens sensor.
David K. Wallace, Don L. Bremer, William V. Good, Rae Fellows, C. Gail Summers, Betty Tung, Robert J. Hardy
Archives of Ophthalmology, Volume 130; doi:10.1001/archophthalmol.2012.2118

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Susan Lewallen, Claudia Perez-Straziota, Van Lansingh, Hans Limburg, Juan Carlos Silva
Archives of Ophthalmology, Volume 130; doi:10.1001/archophthalmol.2012.2147

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Alfred Sommer
Archives of Ophthalmology, Volume 130, pp 1599-1600; doi:10.1001/archophthalmol.2012.2152

Kaweh Mansouri, Felipe A. Medeiros, Ali Tafreshi, Robert N. Weinreb
Archives of Ophthalmology, Volume 130, pp 1534-9; doi:10.1001/archophthalmol.2012.2280

Abstract:OBJECTIVE To examine the safety, tolerability, and reproducibility of intraocular pressure (IOP) patterns during repeated continuous 24-hour IOP monitoring with a contact lens sensor. METHODS Forty patients suspected of having glaucoma (n = 21) or with established glaucoma (n = 19) were studied. Patients participated in two 24-hour IOP monitoring sessions (S1 and S2) at a 1-week interval (SENSIMED Triggerfish CLS; Sensimed AG). Patients pursued daily activities, and sleep behavior was not controlled. Incidence of adverse events and tolerability (visual analog scale score) were assessed. Reproducibility of signal patterns was assessed using Pearson correlations. RESULTS The mean (SD) age of the patients was 55.5 (15.7) years, and 60% were male. Main adverse events were blurred vision (82%), conjunctival hyperemia (80%), and superficial punctate keratitis (15%). The mean (SD) visual analog scale score was 27.2 (18.5) mm in S1 and 23.8 (18.7) mm in S2 (P = .22). Overall correlation between the 2 sessions was 0.59 (0.51 for no glaucoma medication and 0.63 for glaucoma medication) (P = .12). Mean (SD) positive linear slopes of the sensor signal from wake to 2 hours into sleep were detected in both sessions for the no glaucoma medication group (S1: 0.40 [0.34], P < .001; S2: 0.33 [0.30], P < .01) but not for the glaucoma medication group (S1: 0.24 [0.60], P = .06; S2: 0.40 [0.40], P < .001). CONCLUSIONS Repeated use of the contact lens sensor demonstrated good safety and tolerability. The recorded IOP patterns showed fair to good reproducibility, suggesting that data from continuous 24-hour IOP monitoring may be useful in the management of patients with glaucoma. TRIAL REGISTRATION clinicaltrials.gov Identifier: NCT01319617.
Carlos Gustavo De Moraes, Shaban Demirel, Stuart K. Gardiner, Jeffrey M. Liebmann, George A. Cioffi, Robert Ritch, Mae O. Gordon, Michael A. Kass, for the Ocular Hypertension Treatment Study Group
Archives of Ophthalmology, Volume 130; doi:10.1001/archophthalmol.2012.2324

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Sri Krishna Mukkamala, Rogério A. Costa, Adrian Fung, David Sarraf, Roberto Gallego-Pinazo, K. Bailey Freund
Archives of Ophthalmology, Volume 130; doi:10.1001/archophthalmol.2012.2491

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