International Journal of Medical and Pharmaceutical Case Reports

Journal Information
ISSN / EISSN : 2394-109X / 2394-109X
Published by: Sciencedomain International (10.9734)
Total articles ≅ 279
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SHERPA/ROMEO
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, Uma Datta Gupta, Adeel Anwar, SaraL Desai
International Journal of Medical and Pharmaceutical Case Reports pp 25-28; https://doi.org/10.9734/ijmpcr/2021/v14i330136

Abstract:
Risperidone is the first line of treatment for bipolar disorder, atypical depression, and Schizophrenia. We present a 55-year-old male with a history of schizoaffective disorder with bipolar type I presented with aggressive behavior and suicidal ideation. Our patient was treated with low-dose Risperidone; after that, he gradually developed leg pain and edema. His leg pain hampers his ambulation, which is clinically improved after a week of medication discontinuation; however, his leg edema did not resolve completely. In addition, we evaluated our patient's compliance with an empathic verbal interview that shows edema and leg pain hampers his quality of life. We have found that not informing edema as one of the possible side effects increases medication non-compliance in our case. There are several case reports about the side effect of Risperidone (such as leg edema) in combination with other medications, but there is no recommendation about patient counseling of forthcoming leg edema and mobility issues.
, Laresh Mistry, Ashwin Jawdekar
International Journal of Medical and Pharmaceutical Case Reports pp 15-24; https://doi.org/10.9734/ijmpcr/2021/v14i330135

Abstract:
In teeth with pulpal and periapical infection, various group of microorganisms are present. Inhibition of the growth of these microorganisms and suppression of their antimicrobial activity play a crucial role in the success of the endodontic management. Triple antibiotic paste has been reported to have an excellent antimicrobial efficacy and it can be useful in management of teeth with severe infection. A 12-year-old female child reported with pain and swelling in relation with a lower left first permanent molar. Clinical examination of the tooth revealed deep occlusal caries and dentoalveolar abscess. Radiographically, the carious lesion was seen involving the pulp with periodontal ligament widening and inter-radicular bone loss was observed (endo-perio lesion). Considering the position of the tooth and its strategic importance, a conservative approach to salvage the tooth using Triple Antibiotic Paste (TAP) as a medicament was employed with complete radiographic healing by 12 weeks. Subsequent obturation using lateral condensation with gutta percha followed by composite restoration and preformed stainless steel crown was performed. This case report focuses on the endodontic management of perforated first permanent molar with compromised periodontal support and significant bone loss TAP as medicament and Mineral Trioxide Aggregate (MTA) as perforation repair material. Based on the results it can be concluded that Triple Anitibiotic Paste (TAP) can be effective in the disinfection and sterilization of the root canals and repair of complex lesions.
Farheen Tafti, Ashwin Jawdekar
International Journal of Medical and Pharmaceutical Case Reports pp 6-14; https://doi.org/10.9734/ijmpcr/2021/v14i330134

Abstract:
Developmental anomalies may affect the number and morphodifferentiation of teeth. Development of two teeth from one tooth bud gives rise to gemination. Geminated teeth with caries may lead to pulpal pathologies for which extraction may be a preferred treatment. We report a case of geminated maxillary carious primary incisor treated with pulpectomy in a five year-old child.
, Tutul Chowdhury
International Journal of Medical and Pharmaceutical Case Reports pp 1-5; https://doi.org/10.9734/ijmpcr/2021/v14i330133

Abstract:
Friedrich's ataxia is a progressive neurodegenerative disease that affects the posterior cord of the spinal tract. We present a case of an 83-year-old male with resting tremor and rigidity that had gradually worsened over the past few years. The patient has been diagnosed with Friedrich's ataxia. Unlike typical Friedrich ataxia, this patient does not have a shortened life expectancy. There is a small percentage of atypical patients demonstrate late-onset of disease, isolated spastic paraparesis without ataxia, and retained or exacerbated deep tendon reflex. Although there is no association between Parkinson's disease and Friedrich's ataxia; in our case, treatment of tremor and rigidity improves the patient's quality of life.
M. Sow, M. A. Ndour, A. M. Gaye, A. Faye, M. Dieng, N. Diagne, A. C. Ndao, B. S. Kane, B. Djiba, A. Pouye
International Journal of Medical and Pharmaceutical Case Reports pp 20-23; https://doi.org/10.9734/ijmpcr/2021/v14i230132

Abstract:
Aim: We aimed to present a rare case of pseudotumoral tuberculosis of the cervix. Introduction: Tuberculosis has many localizations. Urogenital and particularly cervical involvement is rare. Case Presentation: Our observation concerned a case of pseudotumoral tuberculosis of the uterine cervix simulating a cancer. The clinical signs were pelvic pain and metrorrhagia, which were non-specific. The ulcerative-bourgeons appearance of the cervix was suggestive of cancer. Histology allowed the diagnosis to be made by showing an inflammatory granuloma and the absence of malignant cells. Despite the absence of bacteriological evidence, the clinical, biological, and histological presumptive arguments and the good therapeutic response made it possible to correct the diagnosis. The prognosis of our patient was mainly functional due to the risk of infertility. Conclusion: The interest of this observation lay in the rarity of this tuberculosis localization, especially in an immunocompetent subject, and the predominant place of histology.
Gautam Panduranga, Bavu Akhil Kumar, Mandhala Sai Krishna, Akhil Aakunuri, Nikitha Godishala
International Journal of Medical and Pharmaceutical Case Reports pp 14-19; https://doi.org/10.9734/ijmpcr/2021/v14i230131

Abstract:
Rhino cerebral orbital mucormycosis is an aggressively spreading fungal infection caused by filamentous fungi of the Mucoraceae family and is found to be more prone in patients with comorbidities that include: uncontrolled diabetes mellitus, immune-suppressed patients, iron and aluminum overload, chronic steroid therapy, severe trauma, and protein-energy malnutrition. A 51year old male patient was admitted to the hospital with a complaint of headache and intermittent fever. The patient had no history of diabetes or denovo hypertension. Based on the analysis of histopathological and radiological investigations, the patient was diagnosed with mucormycosis. The patient furthermore underwent an endoscopic surgical debridement followed by standard treatment including antifungal antibiotic(amphotericin-B) and azole antifungals (posaconazole) along with symptomatic treatment. Though the patient was given all possible therapy available, no improvement was seen in the patient's condition (poor prognosis).
Gueye Khadidiatou, Seye Modou, S. Y. Sidy Lamine, Ismael Ibouroi Moina-Hanifa, Gaye Cheikh, B. A. Amadou Baro, Dioum Momar, Diop Ibrahima Bara
International Journal of Medical and Pharmaceutical Case Reports pp 5-9; https://doi.org/10.9734/ijmpcr/2021/v14i230129

Abstract:
Introduction: Coronavirus disease 2019 (COVID 19) is an emerging viral infection caused by the strain of coronavirus SARS-CoV-2, primarily affecting the respiratory system. However, it can be responsible for heart damage. The aim of this work was to report a case of symptomatic myocarditis in a 53-year-old patient. Patient and Observation: We report the case of a 53-year-old patient with no particular history or cardiovascular risk factor found who had consulted in June 2020 in a hospital for dyspnea, dizziness and palpitations in whom the electrocardiogram had demonstrated ventricular tachycardia. The echocardiography was normal and coronary artery disease was ruled out on coronary angiography and antiarrhythmic treatment allowed it to regress. Two months later, after a break in therapy, this tachycardia recurred despite several electrical and chemical cardioversions. Subsequently, myocarditis was suspected. This motivated the realization of a cardiac magnetic resonance imaging (MRI) which came back in favor of myocarditis. As part of the etiological research, RT-PCR and COVID 19 serology were requested and the serology returned positive for IgG. Conclusion: COVID 19 disease is known for its respiratory manifestations. However, several cases of cardiac involvement, in particular myocardial damage, have been described and among these, a considerable proportion of arrhythmias. They can be multifactorial in origin, due to the virus itself, or the prolongation of the QT interval from various drug therapies. These arrhythmias are the source of sudden death, hence the interest of RT-PCR and COVID 19 serology, but also the need for early and appropriate management, as well as long-term monitoring of patients. cured patients.
Anthony A. Iwuafor, Bode Akashie Abraka, Patrick Ntui Mbu, Christian Ide, Princewill Chinedu Erengwa,
International Journal of Medical and Pharmaceutical Case Reports pp 1-4; https://doi.org/10.9734/ijmpcr/2021/v14i230125

Abstract:
Aim: This report highlights the use of doxycycline therapy other than the more standard regimen that includes an aminoglycoside in the management of enterococcal infection in patients with renal impairment without causing further damages to the kidney due to aminoglycoside therapy. Presentation of Case: A case of enteroccocal septicemia in a 29-year-old woman who was admitted on account of acute kidney injury secondary to pregnancy induced hypertension in the setting of pre-eclampsia. She was referred from another centre where she had emergency caesarean section done on account of severe pre-eclampsia at 36 weeks gestational age. Blood culture yielded Enterococcus species. When other antibiotic regimen failed, she was started on doxycycline. Patient had good clinical response and was discharged 7 days after commencement of doxycycline. Discussion: Enteroccoci have emerged as important agent of human disease largely because of their resistance to antimicrobial agents. They are important nosocomial pathogens capable of causing serious and potentially life-threatening infections, including sepsis. The incidence of enteroccocal infections, mainly hospital-acquired, has increased over the past 2 decades and isolates with novel mechanism of resistance to antimicrobial agents are more and more frequent. Furthermore, they have great capacity for transmitting these resistances to other species and even to other genera. Conclusion: Doxycycline is a safe and effective alternative antibiotic for the treatment of enterococcal sepsis in patients with impaired renal status.
, Mudit Varshney, Sandeep Mangla, Binita Jaiswal, Priyanka H. Chhabra
International Journal of Medical and Pharmaceutical Case Reports pp 20-24; https://doi.org/10.9734/ijmpcr/2021/v14i130124

Abstract:
The virus SARS-CoV2 and the disease spectrum caused by it have led to a widespread impact on the medical and economic status of all nations of the world. This led to an expedited mission to introduce a vaccine which could attempt to neutralize the pandemic to some extent. Many vaccines have been introduced with an acceptable safety profile, producing only mild adverse effects of soreness at injection site, malaise, fever, diarrhoea, myalgia and uncommonly allergic/anaphylactic reactions and possibility of getting infected with SARS-CoV2. Some isolated reports have also emerged of serious thromboembolic phenomena and neurological complications such as Guillain-Barré Syndrome (GBS). A similar incident was noticed at our institute, where a 71 year old male recipient of COVID-19 vaccine at an immunization centre, presented to us with features of GBS. We hereby report this case, not establishing a direct link between the two, but to raise awareness regarding the ongoing mass immunization world-wide.
Selda Ghahramani,
International Journal of Medical and Pharmaceutical Case Reports pp 15-19; https://doi.org/10.9734/ijmpcr/2021/v14i130123

Abstract:
Background: There are only a few treatment approaches for periapical abscess as a prevalent complication and as the most common type of dental abscess. Drainage and/or antibiotic therapy is the first step to treat this infection, depending on its severity and symptoms. Case Presentation: Amoxicillin/clavulanate (TID for 3 days), clindamycin (QID for 3 days), and a single local dose of an Iranian home remedy called metmeto, a mixture of toasted flour and ghee covered with a sterile piece of cotton fabric-, were respectively prescribed, for a 32-year-old male patient with a spreading periapical abscess. The first two antibiotics were not able to mitigate the symptoms (pain, inflammation,infection, etc.), while the abscess disappeared remarkably the morning after using a single dose of metmeto “as a dressing” for 6 hours. To eliminate the possible riskof recurrence, the patient underwent an endodontic retreatment after 2 weeks. Conclusion: Some folk home remedies such as metmeto can be considered for treatment of dental problemsas noninvasive and safe choices. Further studies are necessary to conclude a causal association.
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