Gulustan-Black Sea Scientific Journal of Academic Research

Journal Information
ISSN / EISSN : 1987-6521 / 2346-7541
Published by: IRETC (UK, London) (10.36962)
Total articles ≅ 33
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Aynur Badalova
Gulustan-Black Sea Scientific Journal of Academic Research, Volume 57, pp 9-12; https://doi.org/10.36962/gbssjar5706202009

Abstract:
If psychologism artistic method has reached to the high level of development in Azerbaijani literature from the second half of the twentieth century, the development of psychologism in world literature dates back to the beginning of the previous century. Thus, the development of psychologism in Azerbaijani prose associates its roots to world literature. There are many artists in the world literature who write with psychologism method. Many of them can be named. But I would like to focus on the great classic writer Leo Tolstoy. He had influenced to readers' spirit and heart with his works, had an irresistible influence on the development of their personalities by cultivating in them the best human qualities, aroused love to the motherland, people, language, nature and the world. I think that Tolstoy, used the most unique methods of psychologism, also had an impact on Azerbaijani literature. It is more correct to evaluate the manifestation features of psychologism in Azerbaijani prose by conducting comparative analysis. And in this article research has been conducted on the subject of psychologism in L.N. Tolstoy and in the Azerbaijani prose of 1960-1980 within the comparative typological aspect. It had been considered legitimate here identification of not only similarities, but also inconsistencies during the interpretation of the analysis. In the article, in both Azerbaijani prose and Tolstoy's creativity the heroes' spiritual world have been characterized through expression possibilities of psychologism: internal monologues, dialogues, actions and behaviors, dreams and fantasy, writer's prose, etc., and the heroes' appearance have also been shown as part of the image, to create a fuller imagination. As a result, in both Azerbaijani prose and Tolstoy's creativity, different and similar features in the expression methods of psychologism have been extensively analyzed. Keywords: hero, psychologism, character, trait, spiritual world.
Mzia Tsiklauri, Paata Gudushauri, Iamze Taboridze
Gulustan-Black Sea Scientific Journal of Academic Research, Volume 57, pp 04-08; https://doi.org/10.36962/gbssjar5706202004

Abstract:
Objective: The one of the most important issues in traumatology is prevention and treatment of purulent-septic complications of traumatic diseases. The aim of our study was to establish correlations between osteomyelitis caused by bacterial flora and immunological factors. Methods: On the basis of a comprehensive study of bacteriological and immunological data in 100 patients with various etiologies osteomyelitis, using correlation analysis was determined: that the types of microbial complications following trauma and the date of the body's immune system depends on etiological factors. The frequency of microbes is different and depends on the localization of the injury and the surgical intervention. Results: frequency of the etiological factors in the contingent we studied, was distributed as follows: S. aureus-36,9%, S.Epidermidis-52,4, Ps. aeruginosa 27,4%, E. coli- 13,1%, Proteus- 27,4%. Associated infection (or co-infection e.g. S. aureus+S. Epidermidis, or St.Epidermidisis+Ps. Aeruginosa and etc) occurred in 22.6% of cases. A significantly high correlation coefficient was observed in patients who came to the clinics spontaneously or with delay, as well as with the early onset of the infectious process (up to two weeks) and surgical treatment. It also correlates positively with a decrease of following immunological parameters: NK, CD4+, CD8+ and CD 19+, the leucocytes phagocytic index is reduced and the blast transformation reaction of lymphocytes rate was increased. There is a significant correlation with benign outcome of treatment, which indicates that, the patient was sent for outpatient treatment (R=0, 79). Keywords: Trauma, Osteomyelitis, Microorganism, Etiological factor, Immune system data.
Vusale Hajiyeva
Gulustan-Black Sea Scientific Journal of Academic Research, Volume 57, pp 13-17; https://doi.org/10.36962/gbssjar5706202013

Abstract:
This article is devoted to the ways and means of establishing interdisciplinary communication between biology and natural sciences. The main purpose of the research is to explore ways to properly establish interdisciplinary communication in the learning process, as well as in the teaching of biology. In the field of integration in education, it is impossible to achieve success in teaching different subjects, especially without the use of interdisciplinary communication. Integration has become one of the main principles of training in modern period, as well as the basis of the educational process. Teaching subjects at a coherent pace will increase the effectiveness of the perceptual process, as well as accelerate the formation of motivation in the learning process. Teaching biology in conjunction with other natural sciences will help students to form a correct worldview, as well as create a complete and holistic view of the world. However, special attention should be paid to the establishment of interdisciplinary communication in accordance with the age and individual characteristics of students. For this, the right forms and methods must be used. The article provides information about these forms and methods, the mechanisms of their use. It is especially important to establish interdisciplinary links, as well as the form in which they are organized to increase the effectiveness of training. Form means the outward expression of the organized activity. Forms of work organized individually, in groups, in groups and in pairs are used during active learning. Depending on the level of difficulty of the topic and the interdisciplinary relationship created, as well as the age and perceptual characteristics of students, the forms of work should be chosen by the teacher at the stage of lesson planning. In addition, the use of teaching methods in establishing interdisciplinary links is of particular importance. The use of these teaching methods will be of particular importance in the formation of logical, creative, critical thinking in students. Teaching methods include both traditionally used oral, visual, and practical methods, as well as active learning methods used in modern education. Also, the organization of out of class, out of lesson activities and nature excursions is one of the main ways to establish interdisciplinary communication. It is known that it is impossible to fully establish the connection between biology and other natural sciences in the teaching process. The best way to deal with this problem is to turn to out of lesson, out of class activities. Significance Application: Can be used to properly organize interdisciplinary communication in biology classes in secondary schools. Keywords: Integration, training, biology, interdisciplinary communication, method
Maia Matoshvili, Davit Tophuria, Inga Kakhniashvili
Gulustan-Black Sea Scientific Journal of Academic Research, Volume 56, pp 37-40; https://doi.org/10.36962/5605202038

Abstract:
Maintaining healthy skin is important for a healthy body. Many people may develop skin diseases that affect the skin, including cancer, herpes and cellulitis. Some wild plants and their parts are frequently used to treat these diseases. It is also suitable raw material for production of new synthetic agents. A review of some plants for the treatment of skin diseases is provided that summarizes the recent technical advancements. The common medications for topical use include[7]: Antibacterials: These medicines, like bactroban or cleocin, are often used to treat or prevent infection, Anthralin (drithocreme, micanol and others): Although not often used, these help to reduce inflammation and can help treat psoriasis, Antifungal agents: Lamisil, lotrimin and nizoral are few examples of common topical antifungal drugs used to treat skin conditions such as ringworm and athlete's foot Benzoyl peroxide: Creams and other products containing benzoyl peroxide are used to treat acne Coal tar: This topical treatment is available with and without a prescription, in strengths ranging from 0.5% to 5%. Coal tar is used to treat conditions including seborrheic dermatitis (usually in shampoos) or psoriasis. Currently, coal tar is seldom used because it can be slow acting and can cause severe staining of personal clothing and bedding Corticosteroids: These are used to treat skin conditions including eczema and come in many forms including foams, lotions, ointments and creams Retinoids: These medications (such as retin-A and tazorac) are gels or creams derived from vitamin A and are used to treat conditions including acne Salicylic acid: This medication is available in the form of lotions, gels, soaps, shampoos and patches. It should be used sparingly as putting too much on one's body at once can cause toxicity. Salicylic acid is the active ingredient in many skin care products for the treatment of acne and warts.
Aytakin Hasanova
Gulustan-Black Sea Scientific Journal of Academic Research, Volume 55, pp 67-68; https://doi.org/10.36962/gbssjar

Abstract:
Reciprocal translocations are the most common structural chromosomal abnormalities in humans. In this study, the results of cytogenetic analysis performed on a couple with a reproductive history of three abortions and one intrauterine death referred to our laboratory are presented. Normal karyotype (46, XY) in male and reciprocal translocation 46XX t (6; 8) (q25-27; q23) in female were determined. In about 4% of couples with recurrent miscarriages, one of the parents is either a balanced reciprocal translocation or a robertsonian translocation carrier. Therefore, cytogenetic analysis should be recommended to couples with recurrent miscarriages. Keywords: Recurrent Abortions, Fetal Wastage, Reciprocal Translocation
Gazanfar Suleymanov, Sadaqat Ibrahimova, EmilyA Shakhverenova
Gulustan-Black Sea Scientific Journal of Academic Research, Volume 54, pp 32-37; https://doi.org/10.36962/gbssjar5403202032

Abstract:
If should be noted that means gained as a result of development of oil industry have to be directed to develop non-oil industry due to the market requirements. Additionally we can emphasize that new economic models have been worked out to develop more effeciently industrial enterprises in the market relations. In connection with it strategical road map on the economic perspectives “State Program on the development of Azerbaijan Republic industry for 2015-2020-s” accepted on 6 December 2018, has been considered to speed industrializing process. Measurements plan is carried out. Due to the industrializing policy developing cosmic, defence, alternative energy, ship-building and other new fields have been created. Besides new industrial and refining enterprises began to be operated successfully.
Aytakin Hasanova
Gulustan-Black Sea Scientific Journal of Academic Research, Volume 53, pp 08-11; https://doi.org/10.36962/gbssjar5302202008

Abstract:
Heterochromatin of centromeric chromosome regions contains late replicating, largely repetitive DNA. It is suggested that heterochromatin participates in chromosome pairing, crossing-over and in chromosome disjunction control (1,3). Centromeric heterochromatin, a variety of heterochromatin, is a tightly packed form of DNA.Centromeric heterochromatin is a constituent in the formation ofactive centromeres in most higher-order organisms; the domain exists on both mitotic and interphase chromosomes. (4,5,6,8) Centromeric heterochromatin is usually formed on alpha satellite DNA in humans; however, there have been cases where centric heterochromatin and centromeres have formed on originally euchromatin domains lacking alpha satellite DNA; this usually happens as a result of a chromosome breakage event and the formed centromere is called a neocentromere.
Maia Matoshvili, Davit Tophuria Tophuria
Gulustan-Black Sea Scientific Journal of Academic Research, Volume 52, pp 4-7; https://doi.org/10.36962/gbssjar5302202004

Abstract:
The Skin has the natural ability to heal and replace damaged and dead cells regulated by a network of complex immune processes. This ability is conferred by the population of resident immune cells that act in coordination with other players to provide a homeostatic environment under constant challenge. In this article we conclude that near future discoveries using such innovative strategies will not only help us achieve better therapeutic products for skin-related immune disorders but will also foster ideas toward novel cosmetic formulations and topical applications for improving skin’s regenerative potential.
Irine Ioramashvili, Rusudan Sujashvili, Marika Gamkrelidze, Sofia Tsitsilashvili
Gulustan-Black Sea Scientific Journal of Academic Research, Volume 52, pp 34-34; https://doi.org/10.36962/gbssjar5302202034

Abstract:
Gastrointestinal cancers (GI) are one of the most abundant types of cancers among the world population, though statistical data indicate that in eastern Asia these types of cancer occur 4 times more often than in Western Europe. Absence of treatment of bacterial infections, obesity, and lack of vegetable food in a diet can be the case of GI cancer. All pathologies are inevitably connected to the changes in cell cycle, abnormal protein amount and their dysfunction. Serum proteins are widely used as an additional source of information about body condition, also changes in protein composition can point out the mechanism of disease development and effectiveness of treatment. In the presented work we studied protein composition of GI cancer patients in different stages of cancer development, after and before chemotherapy and compared these data to protein composition of healthy control group of voluntaries. Treatment of patients was performed according the guidelines appropriate for the GI cancer. Association of the effectiveness of treatment at the different stages of chemotherapeutic courses and changes of protein composition of blood serum has been assessed. Proteins composition was studies by SDS-PAGE electrophoresis and densitometry analysis. Experimentally gained molecular and statistical information exposed the most vulnerable groups of proteins affected by chemotherapeutic agents indicating targets for searching new biomarkers for treatment effectiveness. Research involving human patients performed in accordance with the requirements of the Council of Europe Convention on Human Rights and Biomedicine, Biomedical Research, as well as the UNESCO Declaration of Bioethics and Human Rights.
Melano Shavgulidze, Eka Chkhartishvili, Mariam Babilodze, Nino Rogava, Nargiz Nachkebia
Gulustan-Black Sea Scientific Journal of Academic Research, Volume 52, pp 35-36; https://doi.org/10.36962/gbssjar5201202035

Abstract:
INTRODUCTION Changes in some forms of motivational-emotional behavior, learning and memory are thought to be characteristic for major depressive disease. However, results existing until today about the character of changes in motivational-emotional and exploratory behavior as well as character of disorders in declarative memory, accompanying major depressive disease, are not unambiguous. Therefore, studying them in animal models of depression is very topical and important. METHODS Experiments were conducted on adult white wild rats (with 250-300 g weight). “Depressive” and “non- depressive” rats were selected according to the level of immobility in forced swim test. Rats with low level of immobility, “non-depressive” rats, constituted control group and rats with high level of immobility, “depressive” rats, constituted the experimental group (10 rats in each). Changes of motivational-emotional and exploratory behavior were studied in open field test. The changes of learning and memory were studied in the fear motivated one trial passive avoidance test considered as the declarative memory test. Experiments were carried out on “non-depressive”, control and “depressive”, experimental groups (10 rats in each). Obtained results were processed statistically by Student’s t-test. RESULTS Sharp decrease in locomotion was found in rats with high level of immobility. It was manifested in a significant decrease of the number of crossed squares. The quantitative indices of vertical activity, vertical standings, head risings, were also sharply decreased. Fear reaction was considerably increased in “depressive” rats, manifested in the significant decrease of the number of entering in the center of open field and grooming and sharp increase in defecation rate. Investigation of the changes of learning and memory in the passive avoidance test has shown that the latency of entering from the light into dark section of passive avoidance camera, in the learning session, was sharply increased in “depressive” rats. They revealed an impaired ability to evaluate the level of danger coming from the brightly illuminated open area and therefore they do not hurry to escape from the dangerous section. The difference between “depressive” and “non-depressive” rats was maintained even after 24 hours from receiving a painful stimulation. In particular, the animals of control group remember that they have received a painful stimulation in dark section during learning session and do not enter there during testing session, whereas the experimental animals with considerable delay but still enter in the dark section during testing session, therefore, they show significant impairment of declarative memory in passive avoidance task. CONCLUSIONS Locomotor and exploratory behavior are impaired and fear motivation is increased in the open field in “depressive” rats with high immobility and low level of monoamines content in the brain. Learning and memory in one of the tests of declarative memory, so called passive avoidance task, is disturbed.
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