International Journal of Advanced Research in Medicine

Journal Information
ISSN / EISSN : 2706-9567 / 2706-9575
Current Publisher: AkiNik Publications (10.22271)
Total articles ≅ 152
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Shirish D Chavan, Vijay S Patil
International Journal of Advanced Research in Medicine, Volume 3, pp 72-74; doi:10.22271/27069567.2021.v3.i1b.104

Abstract:
Background: Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. The present study was conducted to assess serum levels of C-reactive proteins as an indicator of disease activity in pulmonary tuberculosis. Materials and Methods: This cross-sectional study was conducted with 60 new sputum-positive pulmonary tuberculosis cases and 60 healthy subjects in 2020. Baseline serum C-reactive proteins (CRP) levels were measured and the values were correlated to clinical and radiological findings. Results: The mean CRP level (mg/dl) in patients with fever was 66.5 mg/dl and it was 28.2 mg/dl among those without fever. Mean level off CRP in haemoptysis was 50.3 mg/dl and 54.2 mg/dl in those without haemoptysis. Mean levels of CRP were 76.2 mg/dl and 26.5 mg/dl among those with and without tachycardia respectively. Mean level was 78.4 mg/dl with tachypnoea and 27.1 mg/dl among those with no tachypnoea. The mean CRP level in patients with minimal disease was 24.2 mg/dl, and with moderate disease it was 41.8 mg/dl and with advanced disease it was 90.5 mg/dl (P
Shirish D Chavan, Vijay S Patil, Basanagouda K Patil
International Journal of Advanced Research in Medicine, Volume 3, pp 75-77; doi:10.22271/27069567.2021.v3.i1b.105

Abstract:
Background: Chronic obstructive pulmonary disease (COPD), is a heterogeneous collection of diseases with differing causes and pathogenic mechanisms. The present study was conducted to compare thoracic dimensions between normal and COPD subjects. Materials & Methods: 70 patients with COPD and 70 healthy subjects were included in 2 groups. Group I were COPD patients and group II were healthy subjects. Average transverse rib cage diameter, HDI and pulmonary function tests were compared. Results: The mean AP diameter in group I was 10.9mm and in group II was 9.1 mm, transverse diameter was 22.7 mm in group I and 21.0 mm in group II and HDI was 23.7 mm in group I and 20.1 mm in group II. The mean FEV1 in group I was 54.1% and in group II was 89.2, FVC was 47.4 in group I and 91.5 in group II and FEV 1/FVC was 42.6 in group I and 97.2% in group II. The difference was statistically significant (P< 0.05). Conclusion: Thoracic dimensions were increased in COPD patients as compared to healthy subjects.
Faseeh Kak Mohiddina, Midhila Gopinath, Shivakumar Bangalore Raja, Mohammed Hafeez, Emad Mir Abbas, Pavan Raj Nagaraj
International Journal of Advanced Research in Medicine, Volume 3, pp 87-89; doi:10.22271/27069567.2021.v3.i1b.108

Abstract:
Introduction: Varicose veins are tortuous, elongated, dilated veins present subcutaneously characterised by the presence of reflux. Occupations which demand prolonged working hours makes the individual vulnerable for developing varicose veins. Objective: This study was conducted to assess the risk factors involved in the development of varicose veins among Traffic Police Personnel, Bengaluru, Karnataka. Method: A cross sectional study was conducted among 50 participants, where data was collected using a preformed questionnaire prepared by the experts and diagnosis confirmation was established by clinical examination. Results: out of the 50 participants involved in the study, 60% were found to have long work hours >6 hours predisposing them to the development of varicose veins. A similar association was evident with prolonged years of such occupational exposure. Conclusion: Traffic Police Personnel are at high risk of developing varicose veins which can ultimately hamper their quality of life if not timely intervened and followed up.
Gnanendra Dm, Kiran S, Prabhdeep Singh, Pp Bose, Parvesh Kumar Jain
International Journal of Advanced Research in Medicine, Volume 3, pp 01-04; doi:10.22271/27069567.2021.v3.i1a.85

Abstract:
Treatment of patients with RAP is aimed at the specific aetiology. In general, cholecystectomy is carried out in cases of microlithiasis along with clearance of common bile duct. Endoscopic sphincterotomy is advised if there is strong suspicion of SOD. Minor papilla sphincterotomy should be carried out in those with PD but with limited expectations. The study was conducted at Peerless Hospital & B.K. Roy Research Centre, Kolkata, a 300 bedded multi-speciality tertiary care Hospital. It was a prospective, observational study conducted during October 2014-August 2016. All patients with two or more distinct attacks of AP willing to give written informed consent irrespective of their age group without any evidence of CP were included in the study. In the present study EUS was performed on total 70 patients and found 11 to have CP out of 80 patients which was not detected by routine investigations. EUS and MRCP combined, diagnosed 14 patients to have GB & CBD Microliths/Sludge. EUS diagnosed more number of cases as compared to MRCP.
Ramakant Rawat, Amit Varshney
International Journal of Advanced Research in Medicine, Volume 3, pp 33-35; doi:10.22271/27069567.2021.v3.i1a.100

Abstract:
Background: Diabetes mellitus is a disease with a rapidly increasing prevalence. The present study was conducted to assess the serum levels of nitric oxide (NO) among diabetic patients and its correlation with lipid profile as well as oxidative stress. Materials and Methods: 150 cases of type II diabetes were divided into three groups: Group I was type 2 diabetics with dyslipidemia and hyperuricaemia, group II was type 2 diabetics with dyslipidemia and normouricaemia and group III was type 2 diabetics with normolipidemia and normouricaemia. Patient was subjected to estimation of lipid profile. Nitric oxide level was determined. Results: Group I had 35 males and 15 females, group II had 20 males and 30 females and group III had 25 males and 25 females. The mean nitric oxide level (µmol/L) in patients with increased triglyceride level in group I was 46.2, 72.0 in group II and 74.2 in group III and in patients with increased cholesterol level was 34.2 in group I, 54.6 in group II and 72.4 in group III, in patients with increased HDL level was 45.2 in group I, 58.4 in group II and 76.0 in group III and in patients with increased LDL level was 42.0 in group I, 60.4 in group II and 72.1 in group III. There was poor correlation of antioxidants with NO in all groups. Conclusion: Oxidative stress parameters had poor correlation with NO level in all the groups.
Shailendra Singh Rajpoot
International Journal of Advanced Research in Medicine, Volume 3, pp 192-196; doi:10.22271/27069567.2021.v3.i1d.135

Sheik K Zaheer Ahamed, Adrama
International Journal of Advanced Research in Medicine, Volume 3, pp 137-139; doi:10.22271/27069567.2021.v3.i1c.115

Abstract:
Several studies undertaken have been unable to link ABO blood groups to the incidence of malaria and related clinical outcome. There is a paucity of hospital based, comparative studies to investigate the relationship between blood groups types and severity of malarial infections. Several studies undertaken have been unable to link ABO blood groups to the incidence of malaria and related clinical outcome. There is a paucity of hospital based, comparative studies to investigate the relationship between blood groups types and severity of malarial infections.
Sunil Kumar Gulati
International Journal of Advanced Research in Medicine, Volume 3, pp 187-191; doi:10.22271/27069567.2021.v3.i1d.134

Abstract:
Aims: The aim of the study to evaluate the impact of dyslipidemia and hyperglycemia among stroke patients. Material and Methods: This was a cross-sectional study conducted in the Department of Medicine, Metro Hospital and Cancer Research Centre, Jabalpur, MP, India from October 2018 to January 2020. During the study period, a total of 140 stroke patients were admitted out of them, 120 patients were participated in this cross-sectional study. Age, gender, and social status, past medical history (hypertension, diabetes, atrial fibrillation, ischemic heart disease, transient ischemic attack, and previous history of stroke), other risk factors (smoking, alcohol use, and obesity/BMI) and family history were obtained from all the patients. Results: The mean age of 65.9 years with 76.67% of them aged above 50 years, and 66.67% of them were males. The co-morbidity, 94 (78.33%) patients had hypertension, 65(54.17%) patients had diabetes mellitus, and 12(10%) patients had transient ischemic attack. 59 patients (49.17%) were smokers, the majority of the smokers were males, and 13(10.83%) patients were obese with a BMI above 30 kg/m2 with a mean of 32.3 kg/m2. 96 (80%) patients had a family history of hypertension, 63 (52.5%) patients had a family history of stroke and 73(60.83%) patients had a family history of diabetes mellitus. Regarding the lipid profile and hyperglycemia, it was found that, 35 patients (29.17%) had LDL greater than 130 mg/ dl, 23 patients (19.17%) had cholesterol equal or greater than 200 mg/dl, 20(16.67%) patients had TAG equal or greater than 200 mg/dl, 73 (60.83%) patients had low HDL. 63 patients (52.5%) had HbA1C levels equal or greater than 6.5% and 66 patients (55%) had FBG equal or greater than 126 mg/dl. The mean level of cholesterol, LDL, HDL and TAG were 162.7, 115.4, 41.7, and 134.1mg/dl respectively. The mean of the HbA1c was 7.1%, while the mean of FBG was 156mg/dl. Conclusion: Most of the patients with stroke had low HDL levels, high levels of FBG and HbA1c. Hypertension, DM, smoking and family history of HTN and DM are significant risk factors for the incidence of stroke.
Vishwanath Vn, Karan Vn
International Journal of Advanced Research in Medicine, Volume 3, pp 223-225; doi:10.22271/27069567.2021.v3.i1d.143

Abstract:
Renal impairment is associated with significant co-morbidity that increases with progressive renal decline. Once an individual reaches end-stage renal disease. (ESRD), cardiovascular disease (CVD) is responsible for approximately half of deaths. A pre-structured proforma was prepared be used to collect demographic data which included age, gender, occupation history of present illness, Past history, family history and personal history including history of smoking, alcohol. General examination and cardiovascular examination was done according to the proforma. All relevant investigations were done for the all the participants. all the samples were sent to the respective laboratory departments. In the present study majority of the cases presented with Dyspnoea ie.75% (75/100), followed by chest pain in 65% cases (65/100), pedal edema was seen in 40% cases (40/100) and palpitation in 35% cases (35/100). In the present study, 48% (48/100) present with history of Smoking and alcohol, 17% (17/100) cases with only smoking, 5% (05/100) cases with only alcohol, 12% (12/100) cases with Tobacco chewing and 8%(08/100) had NSAIDS use, and 10% (10/100) presented with no history of any addiction.
Shreesh Kadur Jm, Shivaraj Bm, Sharvani S
International Journal of Advanced Research in Medicine, Volume 3, pp 318-320; doi:10.22271/27069567.2021.v3.i1f.156

Abstract:
Organophosphorous (OP) compound poisoning is one of the common cases presenting to medical emergency. Erythrocyte cholinesterase (EchE) and pseudocholinesterase (Butyryl cholinesterase – BchE) are markers used for assessing the severity in OP poisoning. However due to the high expense of this marker there is requirement of better and less expensive marker like Creatinine phosphokinase (CPK). Our study was conducted among hundred patients who presented to the hospital over a period of one year. Thorough clinical examination of patients was done at admission along with laboratory values of serum CPK level assessment. Patients were monitored during hospital stay. Out of study population majority were male and in age group of 21-40 years. Thirty four patients had elevated CPK levels at admission which correlated with development of intermediate syndrome. Thus due to ease of availability and being less expensive CPK levels can be used as prognostic marker in op poisoning.
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