Jurnal Kesehatan Andalas

Journal Information
ISSN / EISSN : 2301-7406 / 2615-1138
Published by: Universitas Andalas (10.25077)
Total articles ≅ 1,298
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Amar Makruf, Fanny Septiani Farhan
Published: 19 June 2021
Jurnal Kesehatan Andalas, Volume 10, pp 39-44; https://doi.org/10.25077/jka.v10i1.1674

Abstract:
Novel Coronavirus (2019-nCoV) is a virus that causes respiratory disease COVID-19 (Coronavirus Disease-2019). COVID-19 can be transmitted through droplets when someone coughs or sneezes. Clean and healthy behavior is one way that can be done to prevent transmission of COVID-19. Objectives: To determined changes in clean and healthy behavior before and during the COVID-19 pandemic in 135 medical students of Muhammadiyah Jakarta University class of 2020. Methods: Data was collected by online questionnaire. The sampling technique was total sampling. Statistical tests were performed by using paired sample t-test. Results: There were changes in clean and healthy behavior before and during the COVID-19 pandemic. Conclusion: Clean and healthy behavior was better during the COVID-19 pandemic among respondents.Keywords: COVID-19, clean and healthy behavior, questionnaire
Annelin Kurniati, Ahmad Fandi, Mardhatillah Sariyanti, Ety Febrianti, Debie Rizqoh
Published: 19 June 2021
Jurnal Kesehatan Andalas, Volume 10, pp 49-57; https://doi.org/10.25077/jka.v10i1.1615

Abstract:
Secondary infection with the dengue virus causes mild to severe manifestations. The distribution of dengue virus serotypes varies in various areas and can change over time. There are four dengue serotypes, namely DENV-1, DENV-2, DENV-3 and DENV-4. Objectives: To knew the distribution of virus serotypes in an area and determined the pathogenesis of the disease, which can cause severe manifestations in patients with secondary infections. Methods: The data taken is the severity of secondary infections and dengue serotypes. The literature search was performed on PMC and Cochrane. Search criteria were performed using keywords (secondary infection * OR secondary dengue infection *) AND (Dengue Virus * OR Dengue Infection * OR Dengue * OR DENV) AND (Serotype * OR Serogroup) AND (severe dengue * OR severity * OR severity of illness indexs * OR dengue fever * OR dengue haemorrhage fever * OR dengue shock syndrome * OR DF * OR DHF * OR DSS *) AND (Indonesia *). Results: Literature study search found 387 literature with five studies conducted the analysis. From the results of the analysis, it was found that secondary infections were more common in patients with recurrent dengue infection with serotype 2 (DENV-2), serotype 3 (DENV-3) and serotype 4 (DENV-4). Conclusion: Secondary infection of dengue virus serotype 2 (DENV-2) and serotype 3 (DENV-3) can cause severe dengue infection.Keywords: Dengue Virus, Indonesia, Secondary Infection, Serotype, Severity
Dinda Risma Putri Anjarsari, Abdul Hanan, Esti Widiani
Published: 19 June 2021
Jurnal Kesehatan Andalas, Volume 10, pp 8-15; https://doi.org/10.25077/jka.v10i1.1601

Abstract:
One of the non-pharmacological treatments that can be done to lower blood pressure is to increase the patient's physical activity, such as Isometric Exercise and Yoga breathing exercises. Objectives: To determined isometric exercise and yoga breathing on reducing blood pressure in hypertension. Methods: This study used a pre-experimental design with a one-group pretest-postest design. The sampling technique was purposive sampling. The number of samples in this study was 25 people. Results: The paired t-test statistical test results were a decrease in blood pressure after being given the intervention of isometric exercise and yoga breathing exercises with a p-value of 0.000 (p<0.05). Conclusion: Isometric exercise and yoga breathing exercises can be an alternative non-pharmacological therapy to reduce blood pressure in hypertension.Keywords: Isometric Exercise, Yoga Breathing Exercise, Hypertension
Genta Pradana, Drajad Priyono
Published: 19 June 2021
Jurnal Kesehatan Andalas, Volume 10, pp 65-69; https://doi.org/10.25077/jka.v10i1.1689

Abstract:
The incidence of alcoholic liquor poisoning (alcoholic liquor) in Indonesia shows a high number. One of the causes of alcohol poisoning is methanol. Methanol poisoning in Indonesia usually occurs as a result of drinking mixed alcohol liquor. It has been reported a male 23 years old with decreased consciousness after drinking oplosan alcohol suspected to contain methanol. The examination reveals that patients has metabolic acidosis, toxic optic neuropathy (TON) and erosive gastritis. Treatment was acidosis correction, prevent formation of metabolites, hemodialysis with supportive and symptomatic teraphy .Keywords: methanol, poisoning, alcohol mixed liquor
Fauzar Fauzar, Roza Kurniati, Farhan Abdullah, Alexander Kam
Published: 19 June 2021
Jurnal Kesehatan Andalas, Volume 10, pp 45-48; https://doi.org/10.25077/jka.v10i1.1684

Abstract:
The rapid increase in the number of Coronavirus Disease 2019 (COVID-19) cases, including in Padang, has led the government to designate several hospitals as referrals for COVID-19 patients. The profile of COVID-19 patients is needed to describe the pattern of this disease in Padang. Objectives: To revealed the profile of COVID-19 patients in SPH, Indonesia. Methods: This was a retrospective study. This study was conducted and collected data of COVID-19 patients from March to June 2020. Results: There are 54 patients with mean age of 50.93 (14.6) years old, 43% male and 57% female. The clinical manifestations are cough (74%), fever (37%), sore throat (22%), and fatigue (35%). There are 82% of patients admitted that they have contacted with other COVID-19 patients or have activities in COVID-19 cluster area, and only 7% have traveled to other cities. The mean length of stay is 31.91 (14.87) days. The mean laboratory data: Hemoglobin 13.7 (1.39) gr/dl, WBC 8,037.04 (2,846.27) /mm3, platelet 274,389 (75,053.80) /mm3, and NLR 3.16 (3.37). Chest radiograph results are bronchopneumonia (22.22%), cardiomegaly (7.41%), and normal (70.37%). Conclusion: The profile of COVID-19 patients in SPH is more in female patients, cough is the most clinical manifestation that appeared, the mean laboratory data (hemoglobin, WBC, and platelet) are normal, and normal chest radiography is the most chest radiograph results in these patients.Kata kunci: COVID-19, Padang, profile
Saskia Arientika Wahyuningrum, Meiskha Bahar, Andri Pramesyanti Pramono
Published: 19 June 2021
Jurnal Kesehatan Andalas, Volume 10, pp 16-22; https://doi.org/10.25077/jka.v10i1.1595

Abstract:
Pneumonia is a lung parenchymal infection caused by Pseudomonas aeruginosa.It is Gram negative bacteria that have developed antibiotic resistance. Actinomycetes are Gram-positive bacteria that produce secondary metabolites which have the ability as antimicrobial. Objectives: To identified the ability of Actinomycetes isolates to inhibit the growth of the bacterium Pseudomonas aeruginosa ATCC 27853. The samples in this experiment were from Kebun Raya Bogor that had been rejuvenated on Starch Casein Agar (SCA). Methods: Six dilution series 10-1; 10-2; 10-3; 10-4; 10-5; 10-6 Actinomycetes isolates were used to observe the inhibition zone of P.aeruginosa growth on Mueller Hinton Agar (MHA) media by diffusion method. Results: The effective incubation time occurred at 24 hours, and then it resulted in the average clear zone diameter of 14.70 mm, 10.57 mm, 8.53 mm, 8.47 mm, 6.97 mm, and 5.30 mm. The results of the One – Way Anova test with p-value = 0.000 (p < 0.005) showed some differences at each concentration to inhibit the growth of P.aeruginosa ATCC 27853 at 24 hours incubation period. Conclusion: The most effective concentration of Actinomycetes isolates that can potentially be antibacterial was the concentration of 10-1 with potential solid inhibitory power.Keywords: Actinomycetes, antibacterial, Pseudomonas aeruginosa
Muhammad Rayhan Braja Gitawama, Netti Suharti, Nora Harminarti
Published: 19 June 2021
Jurnal Kesehatan Andalas, Volume 10, pp 23-28; https://doi.org/10.25077/jka.v10i1.1507

Abstract:
The National Food and Drug Agency has controlled the refill drinking water in drinking water depots and also controlled food at school canteens ranging from elementary, junior high, to high school, but the National Food and Drug Agency never do food quality controlling in canteens at universities. Objectives: To identified the contamination by coliform and E. coli bacteria in drinking water at Andalas University canteen. Methods: This research was descriptive to identify coliform bacteria on 15 drinking water at the Andalas University faculty canteens. Samples were taken directly using a sterile bottle, while data analysis using Most Probable Number (MPN) tables 5-1-1 and the presence of E. coli bacteria colonies from drinking water samples. Results: 9 of 15 water samples were contaminated by coliform bacteria with the highest MPN index of 240/100 ml that was found in 2 samples. From 9 samples containing coliform bacteria, all of them were found to contain E. coli bacteria. Conclusion: Most of the samples were contaminated by coliform and E. coli bacteria. Drinking water served using a kettle was more contaminated than drinking water served using gallons.Keywords: Coliform, Escherichia coli, MPN
Shantika Aqilla Kurnia, Komang Ardi Wahyuningsih
Published: 19 June 2021
Jurnal Kesehatan Andalas, Volume 10, pp 1-7; https://doi.org/10.25077/jka.v10i1.1464

Abstract:
Burns increase tissue damage by free radicals, thus hindering the healing process. Platelet Rich Fibrin (PRF) and Advanced Platelet Rich Fibrin (A-PRF) are autologous fibrin matrices that contain growth factors and have been proven to increase tissue formation and regeneration. Objectives: To determined the effect of applying PRF and A-PRF on deep second-degree burns. Methods: This study was experimental research on twenty male Sprague Dawley rats were randomly divided into four groups. Group A and B as control groups received NaCl 0,9% and silver sulfadiazine ointment, respectively. Group C was given PRF and group D was given A-PRF. Burns are photographed and the area was calculated using the ImageJ application. After 14 days of therapy, the burn areas were excised and made into histological slides. Microscopic study of angiogenesis was observed using a microscope at 400x magnification. Results: Changes in wound surface area in PRF and A-PRF groups were 3,106 cm and 2,333 cm. The number of angiogenesis in PRF and A-PRF groups were 3.88 and 5.88. The data was analyzed using One-Way Anova and the results showed that there were no significant differences between the changes in the wound area and angiogenesis of PRF and A-PRF groups. Conclusion: This study showed that there are no significant differences in changes in wound surface area and angiogenesis of burn injury after topical application of PRF and A-PRF.Keywords: angiogenesis, burn injury, changes in wound surface area, A-PRF, PRF
Vaulinne Basyir, Prima Nanda Fauziah, Akhmad Yogi Pramatirta, Yanwirasti Yanwirasti, Johanes C. Mose, Fadil Oenzil
Published: 24 February 2021
Jurnal Kesehatan Andalas, Volume 9, pp 426-432; https://doi.org/10.25077/jka.v9i4.1513

Abstract:
Preeklamsi merupakan penyebab utama morbiditas dan mortalitas baik maternal maupun perinatal. Tujuan: Menganalisis pengaruh pemberian likopen terhadap kadar sFlt-1 secara in vitro pada sel trofoblas model preeklamsi. Metode: Penelitian ini dilakukan secara eksperimental di Laboratorium Genetika Molekuler dan Kultur Sel Fakultas Kedokteran Universitas Padjadjaran selama periode 2017-2018. Sampel serum diperoleh dari RS. Dr. Hasan Sadikin Bandung, sesuai kriteria inklusi dan eksklusi. Kriteria inklusi adalah pasien yang telah didiagnosis preeklamsi berdasarkan pemeriksaan tekanan darah dan protein urin, dan kriteria eksklusi adalag pasien yang tidak datang kontrol atau tidak bisa dihubungi. Penelitian ini terdiri dari dua tahap, pertama ditentukan nilai LD50 likopen terhadap sel trofoblas kemudian dijadikan dasar nilai konsentrasi yang akan digunakan, selanjutnya dilakukan pemeriksaan sFlt-1 menggunakan metode Elisa pada kultur sel trofoblas kondisi normal dan preeklamsi dengan analisa data menggunakan analisis varians (Anova) dan uji Duncan untuk mengetahui perbedaan antar variabel. Hasil: Nilai LD50 adalah 250 ug/ml dan serial konsentrasi yang digunakan mulai dari 1,953 sampai dengan 125 ug/ml. Didapatkan kadar sFlt-1 menurun secara signifikan (p0,05) dari 39,5445 menjadi 31,1342 pg/ml pada sel trofoblas yang diinduksi dengan serum preeklamsi setelah pemberian konsentrasi likopen sebesar 15,625-31,25 ug/ml yang nilainya mendekati keadaan pada sel trofoblas yang diinduksi serum kehamilan normal. Pemberian likopen dapat menurunkan kadar sFlt-1 pada sel trofoblas preeklamsi. Simpulan: Likopen dapat merubah kadar sFlt-1 dan perubahannya dipengaruhi oleh konsentrasi dan jenis serum.Kata kunci: likopen, preeklampsi, sFlt-1
Jonathan Loody Lukas, Hebert Adrianto, Arief Gunawan Darmanto
Published: 24 February 2021
Jurnal Kesehatan Andalas, Volume 9, pp 387-391; https://doi.org/10.25077/jka.v9i4.1564

Abstract:
Demam Berdarah Dengue (DBD) masih menjadi masalah utama di Indonesia sampai sekarang. Pemanfaatan ikan kepala timah (Aplocheilus panchax / A. panchax) sebagai pengendali vektor secara biologis bertujuan untuk memutus rantai penularan. Tujuan: Menentukan kemampuan predasi dan keefektifan ikan A. panchax jantan dan betina terhadap larva nyamuk Aedes aegypti. Metode: Penelitian ini menggunakan metode post-test only design. Pengamatan dilakukan dengan menghitung jumlah larva yang dipredasi setiap lima menit hingga 20 larva habis termakan kemudian dianalisis dengan independent sample t-test untuk mengetahui rerata kemampuan predasi kedua kelompok ikan. Hasil: (1) ikan betina memakan rerata 9.20 larva per lima menit sedangkan ikan jantan 7.40 larva per lima menit. (2) ikan betina paling cepat menghabiskan 20 larva nyamuk dalam waktu 6 menit 44 detik sedangkan ikan jantan 9 menit 8 detik. Simpulan: Ikan A. panchax betina lebih efektif dari yang jantan sehingga berpotensi untuk dimanfaatkan sebagai pengendalian vektor DBD.Kata kunci: aplocheilus panchax, aedes aegypti, DBD, pengendalian vektor
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