Indonesian Journal of Obstetrics and Gynecology

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ISSN / EISSN : 23386401 / 23387335
Total articles ≅ 313
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Yuli Trisetiyono, Noor Pramono, Syarief T. Hidayat, Widjiati Widjiati
Indonesian Journal of Obstetrics and Gynecology pp 28-33; doi:10.32771/inajog.v8i1.1070

Abstract:
Background: The pathogenesis of endometriosis remains unclear, and involves multifactorial etiologies. The increase in oxidative stress is known to be associated with this disease. Oxidative stress increases angiogenesis and supports the proliferation of endometriosis tissue in the peritoneal cavity. Kebar grass, a medicinal plant, is expected to increase antioxidant defense resulting in decreased oxidative stress, inflammation, angiogenesis, and reduced endometrial tissue implants. Objective: To investigate the effects of Kebar grass extract administration to MDA serum levels, TNF-a and VEGF expression, and the extension of the endometriotic lesions in mice model. Methods: This study was experimentally designed. It was conducted in the Department of Obstetrics Gynecology, Faculty of Medicine Diponegoro, University and Faculty of Veterinary Medicine, Airlangga University. Twenty-one mice were divided into three groups: the first group is control of 7 untreated endometriosis mice model, the second group consisted of 7 mice injected with leuprolide acetate 1mg/kgBB single dose, and the last group consisted of 7 mice fed with Kebar grass extract 3mg/day for 14 days. MDA serum level was measured by spectrophotometry, TNF-a and VEGF expression by IHC using Rammele Scale Index (ImmunoReactive Score), whereas the extension of the endometriotic lesions was measured using computerize tracing. Results: Both Kebar grass extract and leuprolide acetate administration significantly decrease MDA serum levels in endometriosis mice model, compare with the control group, (0.09±0.02 nmol, 0.11±0.07 nmol, and 0.30±0.06 nmol, respectively; p=0.001). TNF-α expression of the group treated with Kebar grass extract was lower than leuprolide acetate and control group (2.43±1.521 %, 4.86±0.458 %, and 7.26±2.898 %, respectively; p=0.002). However, there was no significant difference in VEGF expression among study groups (4.34±2.40 %, 5.11±1.95 %, and 7.40±3.49 % respectively; p=0.116). Finally, the extension of the endometriotic lesions of the mouse models administered with Kebar grass extract and leuprolide acetate was smaller than the control group (0 mm2, 4.54±7.75 mm2, and 34.80±13.09 mm2 respectively; p=0.005). Conclusion: Kebar grass extract has the effect of decreasing MDA serum levels and reducing TNF-α expression, resulted in smaller endometriotic lesions in mice, even though it does not affect VEGF expression. Keywords: malondialdehyde, tumour necrosis factor alpha, vascular endothelial growth factor, endometriotic lesion, kebar grass extract, endometriosis mouse
Risanto Siswosudarmo, Nungky Nugroho, Chandra Kurniawan, Yunita Erlina, Dianisa Ikarumi
Indonesian Journal of Obstetrics and Gynecology pp 14-18; doi:10.32771/inajog.v8i1.1259

Abstract:
Objective: To compare the safety and effectiveness of CuT 380A IUD use inserted by R-inserter compared with those inserted by ring forceps during the postpartum period.Methods: The study was conducted in three puskesmas (community health centre) as affiliated of Sardjito Hospital. Subjects meeting the inclusion and exclusion criteria were recruited to get a 10% proportion expulsion rate difference, type one error 0.05 and type two error 0.20. Insertion using R-inserter was treated while using ring forceps belonged to the control groups. Follow up was carried out one week after the insertion, one month and then monthly for 12months. Rate of the following events i.e.infection, expulsion, pain, bleeding, removal and continuation of use were primary outcomes of interest.Results: A total of 208 eligible subjects were recruited, consisting of 104 subjects using R-inserter and 104 subjects using ring forceps. Cumulative event rates during 12 months follow up were 1%, 4.3%, 3.4%, 10.1% and 4.8% each for infection, expulsion, bleeding, pain, and removal respectively. There was no difference in the rate of infection between the two groups, i.e. 1,0% for each group. There was one pregnancy over 208 subjects giving the overall failure rate of 0.5%. The overall results showed that there were no differences among those events rates (pain, bleeding, removal and continuation) between R-inserter and ring forceps groups. Continuations rate were 93.7%, 93.2%, 90.8%, and 90.8% each for three, six, nine and 12 months follow up respectively.Conclusions: There were no differences in terms of event rates between the use of CuT 380A IUD inserted by R-inserter and ring forceps.Keywords: continuation rate, expulsion, infection, postpartum IUD, R-inserter AbstrakTujuan: Membandingkan keamanan dan keefektifan pemakaian IUD CuT 380A pascasalin yang dipasang dengan R-inserter vs klem cincin.Metode: Penelitian dilakukan di 3 puskesmas di provinsi DIY. Pasien yang memenuhi kriteria kelayakan dimasukkan dalam penelitian ini untuk memenuhi beda proporsi ekspulsi 10%, kesalahan tipe satu 0,05 dan kesalahan tipe dua 0,20. Kelompok uji adalah mereka yang dipasang IUD dengan R-inserter dan kelompok control adalah mereka yang dipasang dengan klem cincin.Follow up dikerjakan setelah satu minggu, satu bulan dan setiap bulan sampai 12 bulan. Infeksi, ekspulsi, nyeri, perdarahan, pelepasan dan kelangsungan pemakaian adalah hasil utama yang diteliti.Hasil: Sebanyak 208 subyek penelitian memenuhi kriteria kelayakan, terdiri atas 104 subyek dipasang dengan R-inserter dan 104 subyek dengan klem cincin. Kejadian kumulatif pada seluruh kasus selama 12 bulan follow up adalah 1%, 4,3%,3,4%, 10,1%, 4,8% masing-masing untuk infeksi, ekspulsi, perdarahan, nyeri, dan pelepasan. Angka infeksi masing-masing sebesar 1% pada kedua kelompok. Terdapat satu kehamilan (0,5%) dari seluruh kasus. Angka kejadian yang lain (nyeri, perdarahan, pelepasan dan kelangsungan pemakaian) tidak menunjukkan perbedaan yang bermakna. Angka kelangsungan pemakaian kumulatif adalah 93,7%, 93,2% 90,8%, dan 90,8% masing-masing pada follow up tiga, enam, Sembilan dan 12 bulan pascapasang.Kesimpulan: Tidak ada perbedaan dalam hal kejadian efek samping antara pemakaian IUD CuT 380A yang dipasang pada masa pascasalin denganR-inserter dan klem cincin.Kata kunci: Angka kelangsungan, ekspulsi, infeksi, IUD pascasalin, pelepasan, R-inserter.
Laila Nuranna, Renny Surya Wardany, Gatot Purwoto, Tofan W. Utami, Lex Peters
Indonesian Journal of Obstetrics and Gynecology pp 61-65; doi:10.32771/inajog.v8i1.1219

Abstract:
Objective: To find out the suitability of Documentation of Visual Inspection with Acetic Acid (DoVIA) result compare to colposcopy result as a method of cervical cancer screening. Method: This is a descriptive study using cross sectional design that took place from April 2017 until March 2019. One hundred eighty two sampels of documentation photographs taken by the researcher were included. The photographs were reviewed by the 3 selected reviewers: oncology and gynecology consultant, obstetry and gynecology resident, and general practitioner that were trained about DoVIA and colposcopy. The review was based on kappa test which assessed the sharpness, squamo-columnar junction and white epitel visualization on the cervix. Results: Kappa score on DoVIA versus colposcopy was 0,717 (good). Inter-rater test was performed to assess consistency and the result was 0,764 (good) between consultant and resident, 0,703 (good) between consultant and general practitioner. Conclusion: Kappa test of IVA documentation ”DoVIA” gives a good kappa value, so that it is expected to be an alternative screening for precancerous lesions. Keyword: cervical cancer screening, VIA, DoVIA, colposcopy, mini colposcopy Abstrak Tujuan: Untuk menemukan kesesuaian antara dokumentasi hasil inspeksi visual dengan asam asetat (DoVIA) dibanding dengan hasil kolposkopi sebagai metode skrining kanker serviks. Metode Penelitian deskripsi ini menggunakan desain cross sectional yang telah dilakukan sejak April 2017 hingga Maret 2019. Seratus delapan puluh dua sampel dokumentasi telah diambil oleh peneliti telah dimasukkan menjadi sampel. Hasil dokumentasi telah dinilai oleh 3 penilai yang terdiri dari konsultan onkologi dan ginekologi, residen obstetri dan ginekologi, dan dokter umum yang telah dilatih untuk DoVIA dan kolposkopi. Hasil penilaian dilakukan berdasarkan kappa untuk menilai ketajaman, sambungan skuamos kolumner dan visualisasi lesi putih di serviks Hasil Skor kappa pada DoVIA dibanding kolposkopi adalah 0,717 (baik). Hasil prbandingan penilaian antar penilai yang ditunjukkan untuk menilai konsistensi dan hasil adalah 0,764 (baik) antara konsultan dan residen, 0,703 (baik) antara konsultan dan dokter umum. Kesimpulan Tes kappa pada dokumentasi IVA (DoVIA) memberikan hasil kappa baik, sehingga DoVIA diharapkan dapat menjadi alternatif skrining untuk lesi prakanker. Kata kunci : skrining kanker serviks, IVA, DoVIA, kolposkopi, minikolposkopi
Tyas Priyatini, Finish Fernando, Lucky S. Widyakusuma, Shirley T. Anggraeni, Kukuh W. Kustarto
Indonesian Journal of Obstetrics and Gynecology pp 52-60; doi:10.32771/inajog.v8i1.1006

Abstract:
Objective: To know sensitivity, specificity and accuracy of Pelvic Organ Prolapse Quantification (POP-Q) to measure cervical length for cervical elongation diagnose in Pelvic Organ Prolapse (POP) patients with gold standard was the anatomical cervical length from hysterectomy result. Methods: Diagnosis research, cross-sectional, consecutive sampling. POP-Q was taken before the operation and the anatomical cervical length was from hysterectomy result Results: Sixty six subject, 1.5% 2nd stage POP, 45.5% 3rd stage POP, and 53.0 % 4th stage POP. Mean (± sd) age and body mass index consecutively59.88 years (± 9.347) and 24.41 (± 3.67) kg/m2. Median (min-max) cervical length POP-Q and anatomy consecutively 4 cm (1-12) and 5 cm (3-10). Sensitivity, Specificity dan Accuracy POP-Q consecutively 79%, 58% dan 68% Conclusion: POP-Q has good specificity (79%) but with less sensitivity (58%) with accuracy 68% to diagnose cervical elongation in POP Keywords: accuracy, cervical elongation, cervical length, pelvic organ prolapse, pelvic organ prolapse quantification (POP-Q), sensitivity, specificity. Abstrak Tujuan: Untuk mengetahui nilai sensitivitas, spesifisitas dan akurasi Pelvic Organ Prolapse Quantification (POP-Q) untuk menilai panjang serviks sebagai diagnosis elongasio serviks pada pasien POP dengan baku emas pengukuran anatomi serviks dari hasil histerektomi. Metode: Uji diagnosis, potong lintang, consecutive sampling. Data diambil dari pemeriksaan POP-Q dan pengukuran anatomi serviks dari hasil histerektomi. Hasil : Enam puluh enam subjek, 1,5% POP derajat 2, 45,5% POP derajat 3 dan 53,0 % POP derajat 4. Rerata(± sb)usia dan Indeks Massa Tubuh (IMT) berturut – turut 59,88 tahun (± 9,347) dan 24,41 (± 3,67) kg/m2. Median (min-maks) panjang serviks POP-Q dan anatomi berturut – turut 4 cm (1-12) dan 5 cm (3-10). Sensitivitas, spesifisitas, dan akurasi POP-Q berturut – turut 79%, 58% dan 68% Kesimpulan : Pemeriksaan POP-Q memiliki spesifitas yang baik (79%) tetapi dengan sensitivitas yang kurang baik (58%) dan akurasi 68% untuk diagnosis elongasio serviks pada prolaps organ panggul. Kata kunci: akurasi, elongasio serviks, panjang serviks, prolaps organ panggul, pelvic organ prolapse quantification (POP-Q), sensitivitas, spesifisitas
Eka R. Gunardi, Jimmy T. Sitorus
Indonesian Journal of Obstetrics and Gynecology pp 19-27; doi:10.32771/inajog.v8i1.1004

Abstract:
Objective: To finding out the change of weight and body mass index (BMI) of single rodlevonorgestrel implant acceptor (Monoplant®).Methods: A cross-sectional descriptive study was conductedusing data changes of weight and BMI obtained from series of measurement which is recorded in patients’ medical record in three years of Monoplant® placement in Raden Saleh Clinic, Jakarta. This method is the part of a research of a bigger phase two in clinical test.Results: From 21 subjects of this research, the average weight and BMI before and after 3 years of Monoplant® placement is gained, i.e. 53.1 (SD 11,0) kg and 22.4 (SD 4.5) kg/m2, and 54.8 (SD 9.4) kg and 23.1 (SD 3.9) kg/m2. Despite the tendency of increasing, statistically the increasing of weight and BMI, however, is meaningless (p=0.09) and (p=0.08). There is a difference of weight in series of measurement, particularly after the 12th month (Repeated test ANOVA p=0.024). Even though there is no difference in BMI average, there is a difference in subject's proportion based on BMI categories before and after Monoplant® placement (Marginal homogeneity test p=0.046). The increasing of levonorgestrel level occurs in the 6th month and subsequently followed by the increase of BMI in the 12th month.Conclusions: There is a tendency of increasing weight and BMI in Monoplant® users, specifically after one year despite statistically insignificant.Keywords: levonorgestrel, monoplant®, weight, body mass index. AbstrakTujuan: Untuk mengetahui perubahan berat badan dan indeks massa tubuh pada akseptor implan levonorgestrel satu batang (Monoplant®).Metode: Studi deskriptif dengan desain potong lintang mengambil data perubahan BB dan IMT diperoleh dari pengukuran serial yang tercatat dalam rekam medis pasien selama tiga tahun pemasangan Monoplant® di Klinik Raden Saleh, Jakarta. Penelitian ini merupakan bagian dari suatu penelitian uji klinis fase 2 yang lebih besar.Hasil: Dari 21 subjek penelitian ini, didapatkan rerata BB dan IMT sebelum dan setelah 3 tahun pemasangan Monoplant®yakni 53,1 (SB 11,0) kg dan 22,4 (SB 4,5) kg/m2, serta 54,8 (SB 9,4) kg dan 23,1 (SB 3,9) kg/m2. Meskipun ada kecenderungan naik, tetapi secara statistik kenaikan BB dan IMT tersebut tidak bermakna (p=0,09) dan (p=0,08). Terdapat perbedaan berat badan dalam pengukuran serial, terutama setelah bulan ke-12 (Uji repeated ANOVA p=0,024). Walaupun tidak terdapat perbedaan rerata IMT, terdapat perbedaan proporsi subjek berdasarkan kategori IMT sebelum dan setelah pemasangan Monoplant® (Uji Marginal homogeinity p=0,046). Peningkatan kadar levonorgestrel terjadi pada bulan ke-6 yang kemudian diikuti oleh kenaikan IMT pada bulan ke-12.Kesimpulan: Terdapat kecenderungan peningkatan BB dan IMT pengguna Monoplant®, khususnya setelah satu tahunmeskipun secara statistik tidak bermakna.Kata kunci: berat badan, indeks massa tubuh, levonorgestrel, monoplant®.
Gita Pratama
Indonesian Journal of Obstetrics and Gynecology pp 3-4; doi:10.32771/inajog.v8i1.1295

Fuad Saddam, Putu A. A. Purbawa
Indonesian Journal of Obstetrics and Gynecology pp 10-13; doi:10.32771/inajog.v8i1.674

Abstract:
Objective: To find out the profile of cesarean section in dr. Zainoel Abidin Hospital since the BPJS era.Methods: This study was a descriptive-observational with retrospective design. The data were obtained in March-April 2017. We collected 3656 data from medical record period January 1st, 2014 - December 31st, 2016.Results: The finding showed there were 1,669 vaginal deliveries (45.65%) and 1,987 cesarean sections (54.35%). The most frequent causes to cesarean sections were induction failure (49.77%), cephalopelvic disproportion (14.33%), pregnancy-induced hypertension (11.21%), malpresentation (8.91), and antepartum haemorrhage (4.33%).Conclusions: The incidence of cesarean sections in dr. Zainoel Abidin Hospital since the BPJS era was 54.35%, increased by 13.29% than the year of 2011-2013 (41.06%) with the most frequent cause is induction failure (49.77%).Keywords: antepartum haemorrhage, BPJS, cesarean section, induction failure, pregnancy-induced hypertension, tertiary referral hospital. Abstrak Tujuan: Mengetahui profil persalinan seksio sesarea di RSUD dr. Zainoel Abidin Banda Aceh pada era BPJS.Metode: Penelitian deskriptif-observasional dengan desain studi retrospektif. Pengambilan data dimulai dari bulan Maret-April 2017. Sebanyak 3656 data dikumpulkan dari rekam medik periode 1 Januari 2014 - 31 Desember 2016.Hasil: Terdapat 1.669 kasus persalinan pervaginam (45,65%) dan 1.987 kasus seksio sesarea (54,35%). Indikasi terbanyak yang menyertai seksio sesarea adalah gagal induksi (49,77%), cephalopelvic disproportion (14,33%), hipertensi dalam kehamilan (11,21%), malpresentasi (8,91%), dan perdarahan antepartum (4,33%).Kesimpulan: Angka seksio sesarea di RSUD dr. Zainoel Abidin meningkat 13,29% sejak berlakunya BPJS (1 Januari 2014-31 Desember 2016) mencapai 54,35% dibandingkan tahun 2011-2013 (41,07%) dengan indikasi terbanyak gagal induksi (49,77%).Kata kunci: BPJS, gagal Induksi, hipertensi dalam kehamilan, perdarahan antepartum, RS rujukan tersier, seksio sesarea.
Joko P. Purwanto, Yusuf Effendi, Heriyadi Manan, Theodorus
Indonesian Journal of Obstetrics and Gynecology pp 44-51; doi:10.32771/inajog.v8i1.1110

Abstract:
Objective: Comparing therapeutic effectiveness, safety profile, and adherence between Dienogest and postoperative Leuprolide Acetate in women with endometriosis who underwent laparoscopy. Methods: This study was a randomized clinical trial comparing the open label study to compare the effectiveness of therapy, safety profile, and obedience between postoperative dienogest and leuprolide acetate in women with endometriosis who underwent laparoscopy. Result: From the statistical test it was found that there was effectiveness of dienogest after 4 weeks of therapy (p = 0.004), after 8 weeks of therapy (p = 0.004) and after 12 weeks of therapy (p = 0.004). In the leuprolide acetate group it was also found that there was effectiveness of administration after 4 weeks of therapy (p = 0.004), after 8 weeks of therapy (p = 0.004) and after 12 weeks of therapy (p = 0.003). There was no difference in systolic blood pressure (p = 0.481), diastolic blood pressure (p = 1,000) and pulse frequency (p = 0.125) breath frequency (p = 1,000) and temperature (p = 0.236) between patients who received dienogest and leuprolide acetate. From the statistical analysis it was found that there were no differences in side effects in patients who received dienogest and leuprolide acetate (p = 0.238). Conclusion: There was no difference in therapeutic effectiveness, and the safety profile assessed by side effects as well as obedience of postoperative Dienogest and Leuprolide Acetate in endometriosis women undergoing Laparoscopy because in both groups there was a decrease in VAS scores from week to week. Key Word: Dienogest, Leuprolide Acetate, Endometriosis, Post-Laparoscopy, Therapy Abstrak Tujuan: Membandingkan efektivitas terapi, profil keamanan, dan kepatuhan antara Dienogest dengan Leuprolid Asetat pascaoperatif pada wanita endometriosis yang menjalani Lapararoskopi. Metode: Penelitian ini merupakan uji klinik acak berpembanding dengan open label study untuk membandingkan efektivitas terapi, profil keamanan, dan kepatuhan antara dienogest dan leuprolid asetat pascaoperatif pada wanita endometriosis yang menjalani lapararoskopi. Hasil: Dari uji statistik didapatkan hasil terdapat efektivitas pemberian dienogest setelah 4 minggu terapi (p = 0,004), setelah 8 minggu terapi (p = 0,004) dan setelah 12 minggu terapi (p = 0,004). Pada kelompok leuprolid asetat juga didapatkan hasil terdapat efektivitas pemberian setelah 4 minggu terapi (p = 0,004), setelah 8 minggu terapi (p = 0,004) dan setelah 12 minggu terapi (p = 0,003). Tidak terdapat perbedaan tekanan darah sistolik (p = 0,481), tekanan darah diastolik (p = 1,000) dan frekuensi nadi (p = 0,125) frekuensi napas (p = 1,000) dan suhu (p = 0,236) antara pasien yang mendapatkan dienogest dan leuprolid asetat. Dari analisa statistik didapatkan hasil tidak terdapat perbedaan efek samping pada pasien yang mendapatkan dienogest dan leuprolid asetat (p = 0,238). Kesimpulan: Tidak terdapat perbedaan efektivitas terapi, dan profil keamanan yang dinilai dari efek samping serta kepatuhan Dienogest dan Leuprolid Asetat pascaoperatif pada wanita endometriosis yang menjalani Lapararoskopi karena pada kedua kelompok terdapat penurunan VAS skor dari minggu ke minggu.
Mohd. Andalas, Cut R. Maharani, Raudhatul Jannah, Siti Harisah, Muhammad Haekal, Ichsan
Indonesian Journal of Obstetrics and Gynecology pp 5-9; doi:10.32771/inajog.v8i1.1028

Abstract:
Objective: to find out the profile of caesarean section in dr. Zainoel Abidin Hospital since the BPJS era. Methods: This study was a descriptive-observational with retrospective design. The data were obtained in March-April 2017. We collected 3656 data from medical record period January 1st, 2014- December 31st, 2016. Results: The finding showed there were 1669 vaginal deliveries (45,65%) and 1987 caesarean sections (54,35%). The most frequent causes to caesarean sections were induction failure (49,77%), cephalopelvic disproportion (14,33%), pregnancy induced hypertension (11,21%), malpresentation (8,91), and antepartum haemorrhage (4,33%). Conclusion: The incidence of caesarean sections in dr. Zainoel Abidin Hospital since the BPJS era was 54,35%, increased by 13,29% than the year of 2011-2013 (41,06%) with the most frequent cause is induction failure (49,77%). Keywords: Antepartum haemorrhage, BPJS, Caesarean section, Induction failure, Pregnancy induced hypertension, Tertiary referral hospital. Abstrak Tujuan: Mengetahui profil persalinan seksio sesarea di RSUD dr. Zainoel Abidin Banda Aceh pada era BPJS. Metode: Penelitian deskriptif-observasional dengan desain studi retrospektif. Pengambilan data dimulai dari bulan Maret-April 2017. Sebanyak 3656 data dikumpulkan dari rekam medik periode 1 Januari 2014- 31 Desember 2016. Hasil: Terdapat 1669 kasus persalinan pervaginam (45,65%) dan 1987 kasus seksio sesarea (54,35%). Indikasi terbanyak yang menyertai seksio sesarea adalah gagal induksi (49,77%), cephalopelvic disproportion (14,33%), hipertensi dalam kehamilan (11,21%), malpresentasi (8,91%), dan perdarahan antepartum (4,33%). Kesimpulan: Angka seksio sesarea di RSUD dr. Zainoel Abidin meningkat 13,29% sejak berlakunya BPJS (1 Januari 2014-31 Desember 2016) mencapai 54,35% dibandingkan tahun 2011-2013 (41,07%) dengan indikasi terbanyak gagal induksi (49,77%). Kata kunci: Perdarahan Antepartum, BPJS, Seksio sesarea, Gagal Induksi, Hipertensi dalam kehamilan, RS Rujukan Tersier.
Suskhan Djusad, Surahman Hakim, Raymond Surya, Hansens Yansah, Ali Sungkar
Indonesian Journal of Obstetrics and Gynecology pp 66-69; doi:10.32771/inajog.v7i4.768

Abstract:
Objective: To review the outcome of percutaneous mitral balloon commissurotomy (PMBC) both to maternal and neonatal. Methods: The search was conducted on Pubmed®, Cochrane Library®, and Ovid® using MeSH. Critical appraisal determining the validity, importance, and applicability (VIA) was conducted by two independent authors. Results: Several studies showed that performing the PMBC had good outcome for pregnant women functional class based on NYHA. Most of them decreased from NYHA III/IV to I/II. For delivery outcome, all studies concluded that more than 80% pregnant women with mitral stenosis undergoing PMBC delivered at term, and no congenital anomalies found. Conclusion: Percutaneous mitral balloon commissurotomy for pregnant women with severe MS is safe during pregnancy. Keywords: mitral stenosis, outcome, percutaneous mitral balloon commissurotomy, pregnancy, Abstrak Tujuan: Mengulas luaran komisurotomi balon mitral perkutan (KBMP) baik pada maternal maupun neonatus. Metode: Pencarian dilakukan melalui Pubmed®, Cochrane Library®, dan Ovid® menggunakan MeSH. Telaah kristis dilakukan oleh 2 penulis independen berdasarkan validitas, kepentingan, dan aplikabilitas. Hasil: Beberapa studi memperlihatkan KBMP memiliki luaran yang baik di kalangan perempuan hamil berdasarkan kelas fungsional NYHA. Kebanyakan mereka mengalami penurunan NYHA dari III/IV menjadi I/II. Untuk luaran persalinan, seluruh studi menyimpulkan lebih dari 80% perempuan dengan mitral stenosis yang menjalani pembedahan KBMP melahirkan pada usia term dan tidak ditemukan kelainan. Kesimpulan: KBMP aman dilakukan pada perempuan hamil dengan mitral stenosis berat. Kata kunci: kehamilan, komisurotomibalon mitral perkutan, luaran, stenosis mitral
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