Endocrine

Journal Information
ISSN / EISSN : 0969-711X / 0969-711X
Published by: Springer Nature (10.1007)
Total articles ≅ 5,272
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Giulia Puliani, Franz Sesti, Emanuela Anastasi, Monica Verrico, Maria Grazia Tarsitano, Tiziana Feola, Federica Campolo, Cira Rosaria Tiziana Di Gioia, Mary Anna Venneri, Antonio Angeloni, et al.
Published: 28 January 2022
The publisher has not yet granted permission to display this abstract.
, Dominik M. Marciniak, Karolina Sutkowska, , ,
Published: 24 January 2022
Abstract:
Purpose: The aim the study was to assess the impact of the lockdown due to COVID-19 on diabetes control. Methods: The HbA1c value from a pre-lockdown visit (V1) from patients with diabetes was compared to the lockdown visit one (V2) after 3–5 months of its duration. Additional information on how the HbA1c changed and which variables can modify HbA1c during lockdown was also studied. Results: Records from 65 patients (type 2 diabetes −96,9%) were eligible and revealed that: HbA1c was at the target in 60% of the patients at V2 compared to 40% at V1; HbA1c decreased and normalized in 19, but worsened in 4 participants during the lockdown. No impact on HbA1c of: sex, age, diabetes duration, therapy type and modification before the pandemic, abandonment of the treatment, previous problems with glycemic control, or change in body weight and physical activity during the lockdown, was found. The previous macrovascular complications were the only variable that affected the increase in HbA1c (p = 0.0072), OR = 5.33. Conclusions: The COVID-19 pandemic has not revealed worsened glycemic control in patients with type 2 diabetes, in general. The patients with macrovascular complications turned out to be at risk of the harmful impact of the restrictions on the HbA1c.
Lingqian Zhao, Fan Wu, Tianhan Zhou, Kaining Lu, Kecheng Jiang, Yu Zhang,
Published: 24 January 2022
The publisher has not yet granted permission to display this abstract.
M. C. Guijt, A. H. Zamanipoor Najafabadi, I. C. Notting, A. M. Pereira, M. J. T. Verstegen, N. R. Biermasz, W. R. van Furth,
Published: 24 January 2022
Abstract:
Purpose: The condition of pituitary apoplexia contains the clinical spectre from life-threatening emergency to asymptomatic self-limiting course, which partly determines diagnostic delay and management. Outcome evaluation of course and management of pituitary apoplexia is hampered by the diverse presentation of this condition and requires appraisal. This study aimed to describe the patient journey, clinical presentation, and management of various types of pituitary apoplexy in a new classification to facilitate future outcome evaluation and identify unmet needs in the care process. Methods: A single-center retrospective patient chart study was conducted between 2005–2021 (N = 98). Outcome measures were clinical symptoms at first presentation in hospital, being headache, consciousness, visual acuity, visual field defects (VFD), ophthalmoplegia, nausea, vomiting, fever, and hypopituitarism and care process characteristics. Results: Mean age was 47.6 ± 16.6 years (51.0% male). We describe their patient journey and identified three different types, differing in clinical presentation, in-hospital route, and final treatment, e.g., Acute (type A, 52%), Subacute (type B, 22.5%), and Non-acute (type C, 25.5%). Type A generally presents with acute onset headaches, VFD, or ophthalmoplegia emergency setting, with lowest mean visual acuity of both eyes and frequent hypocortisolism. Conclusions: Pituitary apoplexy can be approached as a spectrum of disease with 3 main subtypes, with a different initial presentation, different in-hospital route resulting in different management. Acknowledging subtypes with particular needs for (emergency) referrals to Pituitary Tumors Center of Excellence (PTCOE) will serve patient care improvements, outcome evaluations and address areas for improvement.
Min Chen, Qianhui Zhang, Yanhong Wei, Qianqian Wan, Min Xu,
Published: 24 January 2022
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Jingzhen Li, Jingyi Lu, Igbe Tobore, Yuhang Liu, Abhishek Kandwal, Lei Wang, Xiaojing Ma, Wei Lu, Yuqian Bao, , et al.
Published: 23 January 2022
The publisher has not yet granted permission to display this abstract.
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