Open Journal of Obstetrics and Gynecology

Journal Information
ISSN / EISSN : 2160-8792 / 2160-8806
Published by: Scientific Research Publishing, Inc. (10.4236)
Total articles ≅ 1,366
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Amjaad Althaqafi, Renad Hashem Ateeq, Douaa Mohammed Al-Bukhar, Daniyah Hassan Danish, Raghad Alamoudi, Hassan S. O. Abduljabbar
Open Journal of Obstetrics and Gynecology, Volume 11, pp 12-19; doi:10.4236/ojog.2021.111002

Abstract:
Background: Meconium stained amniotic fluid (MSAF), especially observed before term, is considered a sign of fetal jeopardy. Although many studies characterized this condition and associated it with delivery mode, data is lacking in this area, Saudi Arabia. Thus, we attempted to study it. Methods: All data were retrieved from pregnant patients with MSAF who delivered at King Abdul, Saudi Arabia, from January 2015 to December 2018. Results: 758 showed MSAF, of which 83% had vaginal delivery, whereas remaining 17% had an emergency caesarean section. Of them, 32 (4.2%) infants developed meconium aspiration syndrome, and 7 (21.8%) were admitted to the NICU. Conclusion: It was reconfirmed that MSAF is associated with a newborn risk, especially meconium aspiration syndrome. Patients had a higher rate for emergent caesarean section and baby admission to NICU. These data may be useful to make health/reproductive-health poly-making in this area.
Suzan Samir Elsharkawy, Mohamed Abd Elrheem, Samia Abd Elrheem
Open Journal of Obstetrics and Gynecology, Volume 11, pp 146-161; doi:10.4236/ojog.2021.112017

Abstract:
Tumor infiltrating lymphocytes (TILs) are used in evaluating the prognosis and determining treatment of different types of cancer with variable degrees of success. The usage of checkpoint inhibitor immunotherapy as a treatment variety for cancer and Adoptive cell therapy is associated with many complications, severe side effects and high expenses. Recently, in a limited number of metastatic GIT and breast cancers, the identification of T-cell specific against so-called tumor neo-antigens and Adoptive transfer of those lymphocytes resulted in some improvement. In 2020, Detection of a T cell receptor (TCR) in a T cell clone that recognized and killed most human cancer cell lines in vitro via the monomorphic MHC class I-related protein MR1, offers an opportunity for pan-cancer therapy Twenty three years earlier, Moist Heat was used successfully to activate a whole different and new immune response that was able to detect genetic mutation in the affected cancer cells and cured many cases of squamous and basal cell carcinomas. In this commentary review, we aimed to revise the literature for updates of TILs usage in cancer prognosis and treatment.
Jaime Salvador-Moysén, Blanca Edith Cobián-López, Yolanda Martínez-López, Edgar Felipe Lares-Bayona, María Del Socorro Páez-Güereca
Open Journal of Obstetrics and Gynecology, Volume 11, pp 102-116; doi:10.4236/ojog.2021.112012

Abstract:
Objective: To present the results of a pilot study that evaluated the psycho-emotional well-being, and the perinatal results of a group of 44 women who attended a prenatal program that incorporates playful and educational activities, in a Child Development Center in Durango. Mexico. Methods: A group of 44 women with informed consent participated for 28 weeks in the prenatal program. The condition of psycho-emotional well-being during the first and third trimesters and the perinatal results were analyzed with validated instruments. Physiological stress was also assessed with salivary cortisol in the same trimesters. Results: More than 90% of the women evaluated their psycho-emotional condition as satisfactory and very satisfactory. The evaluation of anxiety in its Trait/State modalities placed the participants in the category of mild and moderate. Salivary cortisol showed values within a normal range. Perinatal results showed that 98% of deliveries were at term, 93% of newborns weighed more than 2500 grams, and 98% of newborns had an APGAR score of 9 at 5 minutes. Conclusion: The results suggest that the incorporation of playful and educational actions to prenatal surveillance positively influenced the biopsychosocial condition of the pregnant woman and favorable perinatal outcomes.
Sara Marzook
Open Journal of Obstetrics and Gynecology, Volume 11, pp 183-188; doi:10.4236/ojog.2021.112019

Abstract:
Objective: To report a case of Endometriosis associated with Pleural effusion. Design: Case report. Setting: Tertiary care center. Patient(s): A 30-year old woman presented with a right pleural effusion complicated with pneumothorax-mimicking TB. Intervention(s): Thoracentesis, pleural biopsy by a video-assisted thoracic surgery, pleurodesis, thoracic wedge resection, CT chest, CT Abdomen, and diagnostic Laparoscopy. Main Outcome Measure(s): After taking a GnRH analog, there was no recurrence of pleural effusion nor ascites. Result(s): Thoracentesis and wedge resection of lung ruled out malignancy. An omental mass biopsy obtained from diagnostic laparoscopy after the patient returned with drug-induced hepatitis, and ascites revealed endometriosis. Conclusion(s): Thoracic endometriosis is rare; however, it should be considered in the differential diagnosis by unknown causes of pleural effusion in reproductive age timeframe in women.
Mahamadou Diassana, Ballan Macalou, Sitapha Dembele, A. Sidibe, A. Hamido, D. Konate, Soumana Oumar Traore, Mamadou Sima, Cheickna Sylla, Amadou Bocoum, et al.
Open Journal of Obstetrics and Gynecology, Volume 11, pp 578-590; doi:10.4236/ojog.2021.115054

Abstract:
Objective: The purpose of this study was to assess the risk factors associated with seat presentation and to determine the maternal-fetal prognosis of delivery in the presentation of the seat. Materials and methods: This was a descriptive, cross-sectional and analytical case-control study with prospective data collection, from January 1, 2018 to December 31, 2019, a 12-month period at Kayes Hospital, Mali. Results: During our study period we recorded 3820 deliveries, including 120 breos; a frequency of 3.14% of all deliveries. The 20 - 35 age group was the most represented in cases 61.7%. Of the cases 66.7% (n-80) were out of school, we note 75.8% (n-182) of out-of-school controls. Primiparaes were the majority among cases 39.2% (n-47), as were 39.1% of the controls (n-118). The cases had a history of caesarean section at 15% (n-18); 13, 3% (n-32). The most common mode of presentation was the 70% decomplete seat. It was mainly the anterior left sacro iliac variety (85.8%). The low pathway was preferred during these deliveries to 70% against 30% of caesarean section of which 28.3% of cases were carried out in an emergency. Several factors such as delivery pathway, mode of presentation, length of expulsion and obstetric manoeuvres used influenced fetal prognosis. Fetal complications were dominated by acute fetal suffering (15.8%), followed by dislocation of the shoulder (0.8%). The most common morbid maternal complications were soft part tears (15 cases or 12.5%) and parietal suppuration (1 case or 0.8%). We did not record any maternal deaths. Conclusion: Our results confirm that childbirth is a risky delivery, and must require careful selection of eligible cases and rigorous management of labour with trained teams. In these circumstances, it seems totally abusive to advocate as a single mode of delivery caesarean section in all presentations of the chair in the primigestes.
Desmawati, Waraporn Kongsuwan, Warangkana Chatchawet
Open Journal of Obstetrics and Gynecology, Volume 11, pp 27-39; doi:10.4236/ojog.2021.111004

Abstract:
Background: Many factors influence the expressions of pain in primiparous women aside from contractions of the uterus. Objective: This study aimed to describe the level labor pain, level of labor pain behaviors based on cultural pain behaviors at 3 - 4 cm of cervical dilation or the beginning of the active phase of labor among primiparous Muslim women in Indonesia. Methods: This was a study with 42 primiparous Muslim women who gave birth in the labor room at Bhinneka Bhakti Husada Hospital and Community Health Center Pamulang, Indonesia from June until January 2017. The women were asked to describe on a 100 mm Visual Analogue Scale the intensity of level of labor pain in their abdomen during the last contractions at 3 - 4 cm of cervical dilation, and Pain Behaviors Observation Scale to observe pain behaviors. Descriptive statistics were used to analyze the data. Results: The findings showed that the mean score of level of labor pain at 3 - 4 cm of cervical dilation was 86.38 (SD = 4.47) and most participants experienced high level of labor pain (97.6%). The expression of cultural labor pain behaviors including saying praises to Allah, Asma’aul husna, reciting the Qur’an, sholawat.
A. Ouattara, Y. A. Sawagogo, S. Kiemtoré, I. Ouédraogo, F. D. Traoré/millogo, C. M. R. Ouédraogo, B. Thieba/bonané
Open Journal of Obstetrics and Gynecology, Volume 11, pp 53-62; doi:10.4236/ojog.2021.111007

Abstract:
Objective: To study the place of simulation in the learning of newborn resuscitation among seventh year medical students at the University Hospital of Bogodogo in Ouagadougou, Burkina Faso. Material and Method: Our study took place in the obstetrical gynaecology department of the University Hospital Centre of Bogodogo (UTH-B) from 15 December 2018 to 15 March 2019. We randomly selected two groups of students, with no stimulation. We recorded a theoretical questionnaire to all students at the beginning and then carried out two stimulation sessions at 1 month intervals in the competence laboratory of the National School of Public Health. Then we evaluated the theoretical and practical progress of the students over time. We analyzed our data through the Epi info software in version 3.5.1. Results: The two simulation sessions positively influenced the theoretical knowledge of neonatal intensive care for 7th year students (p = 0.0391). Neonatal resuscitation management by students is better from one simulation session to another with a statistically significant difference (p = 0.0001). Conclusion: Our study of 7th grade students showed the importance of this tool in their practical training at the University Hospital of Bogodogo. Advocacy must be organized for its acquisition in the university hospitals of Burkina Faso.
Hanne De Mulder, Kieran Dempster-Rivett
Open Journal of Obstetrics and Gynecology, Volume 11, pp 303-308; doi:10.4236/ojog.2021.113030

Abstract:
Pregnant women sometimes have thyroid disease, and thus goiter; however, it does not become so large to the extent that the goiter obstructs the air way, causing respiratory symptoms. Here, we report such a case. A 27-year-old woman with large goiter presented with life threatening stridor at 37 weeks. After a multidisciplinary-team discussion, we performed caesarean section plus thyroidectomy, which resulted in good outcomes. Histological examination revealed hyperplasia and not malignancy. The postoperative course was uneventful. The mother and infant were healthy.
Adel E. El-Gegawy, Hashem A. Lotfy, Shereef L. Elshwaikh
Open Journal of Obstetrics and Gynecology, Volume 11, pp 327-337; doi:10.4236/ojog.2021.114033

Abstract:
Aim: To evaluate the safety and efficacy of intralipid infusion in addition to other lines of treatment in reduction of complications caused by antiphospholipid antibody syndrome. Methods: This study was held in the period from June 1, 2016, to December 1, 2019. This study was conducted in the Department of Obstetrics and Gynecology, Tanta University on patients attending the antenatal care clinic and also on patients attending the researcher’s private clinics for antenatal care, 105 patients were enrolled after application of strict inclusion and exclusion criteria. They were randomized into 2 groups. In group A (study group 1) the patients received in addition to the conventional basic treatment of APS, intralipid 20% (Frezenius, Clayton, NC, USA) in a dose of 4 ml diluted in 250 ml 0.9% regular saline IV and to be repeated every 2 weeks. In group B (control group 2) the patients received the conventional basic treatment of APS. The outcome measures were the incidence of pregnancy complications of APS namely fetal loss, premature delivery, IUGR and preeclampsia. Results: 49 patients were enrolled in the study group, and 48 patients were enrolled in the control group, after exclusion of the skipped cases. The demographic data and the gestational age at the beginning of the study show insignificant differences. There were insignificant differences as regard the gestational age at which the pregnancy was terminated and fetal birth weight in patients with positive ACL test, positive LA test and positive B2 however the mean gestational age at which pregnancy was terminated was higher in study group. Also, there was insignificant difference as regards no of patients who complicated with abortion or who completed to full term. But had significant decrease number of case who complicated with preeclampsia (8, 21 patients in study and control group respectively). Conclusion: Intralipid infusion is a promising treatment option for control and prevention of problems caused by antiphospholipid antibody syndrome.
Conway Xu, Shannon M. Osborne, Jonia Alshiek, S. Abbas Shobeiri, Rachel K. Casey
Open Journal of Obstetrics and Gynecology, Volume 11, pp 355-359; doi:10.4236/ojog.2021.114035

Abstract:
Background: Obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome is a rare congenital condition of the female urogenital tract, presenting intraoperative challenges. We demonstrate the utility of three dimensional intraoperative ultrasound to better delineate anatomy and aid in optimal resection of the vaginal septum. Case: A 12-year-old female was referred to pediatric and adolescent gynecology for irregular periods and evaluation of her gynecologic organs. Imaging studies confirmed OHVIRA syndrome. She underwent uncomplicated vaginal septum resection, guided by three dimensional intraoperative ultrasound. Summary and Conclusion: Intraoperative ultrasound can better delineate challenging anatomy. We show that three dimensional intraoperative ultrasound offers significant advantages over traditional two dimensional ultrasound and is a supplement to MRI, which may be helpful in complex anatomical cases like OHVIRA syndrome.
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