International Journal of Scientific Reports

Journal Information
ISSN / EISSN : 2454-2156 / 2454-2164
Published by: Medip Academy (10.18203)
Total articles ≅ 567
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Sushanta K. Das, Varshini R. Ganta, Suvarna A., Sushma P. Kakarlamudi, Pranav S.
International Journal of Scientific Reports; https://doi.org/10.18203/issn.2454-2156.intjscirep20222071

Abstract:
Background: The aim of the work was a prospective study of utilization review for multiple antibiotics prescribed in the specialty department in a tertiary care teaching hospital. Methods: A prospective study was conducted for 6 months in specialty department in a tertiary care teaching hospital. Results: In the 6 months duration of the study, a total number of 96 prescriptions were analyzed. The 77 prescriptions were prescribed with Beta-lactam antibiotics. and remaining prescriptions were prescribed with 2, 3 and 4-5 different classes of antibiotics. Conclusions: The result obtained from our study is for judgment use of antibiotics will reduce the burden of multi-drug resistance and thereby enable better patient management and limit patient morbidity and mortality.
Kirthanashri S. Vasanthan, Deborah Sybil, Priyanshu Kumar Shrivastava, Tanveer Ahmad
International Journal of Scientific Reports; https://doi.org/10.18203/issn.2454-2156.intjscirep20222063

Abstract:
Gelatin methacrylate (GelMA) due to its good biocompatibility, modifiable physical properties, and promotion of cellular adhesion, proliferation, and differentiation, serves as excellent scaffolds in tissue engineering and regeneration. These properties of GelMA make it a suitable choice for engineering of tooth and its supporting tissues. The complex spatial arrangement of the tooth along with the anisotropic nature of different tissues associated with it, make its regeneration challenging. Bioprinted GelMA scaffolds offer a great potential in mimicking the tooth architecture. In this study, GelMA scaffold was constructed by one pot method. The Fourier Transfer Infra red spectroscopy of GelMA confirmed the presence of amide bond at 1650 cm-1 (C=O stretching), 1550-1 (C-N stretching) and 1450-1. As evident from previous studies, the application of GelMA in whole tooth regeneration has not been studied exhaustively. However, GelMA has produced effective results in the regeneration of individual tooth components as well as the tooth germ. Therefore, this scaffold is proposed to be used in the whole tooth regeneration process because of its cytocompatiblity, cellular adhesion and tuneable mechanical properties.
Girum T. Assefa, Tihut Z. Asfaw
International Journal of Scientific Reports, Volume 8, pp 231-235; https://doi.org/10.18203/issn.2454-2156.intjscirep20221837

Abstract:
Ethiopia is one of the countries with high burden of pulmonary tuberculosis and the number of cases of extra pulmonary is increasing. However, diagnostic evidence to initiate anti-tuberculosis treatment among extra pulmonary tuberculosis (EPTB) cases is not well known. We presented here a case of isolated tuberculosis epididymitis with scrotal sinus after developing nonspecific testicular symptoms for more than 2 months and review the literature. Tuberculous epididymitis is a form of urogenital tuberculosis that is particularly rare and has the same clinical manifestation that mimics other more common infectious causes of epididymitis, leading to delay in diagnosis. So, one should maintain a high-index of suspicion to accurately diagnose tuberculous epididymitis in individuals presenting with suggestive signs and symptoms.
Saeed Pourmoghaddam, Atefeh Shadman, Afrouz Mardi
International Journal of Scientific Reports, Volume 8, pp 215-220; https://doi.org/10.18203/issn.2454-2156.intjscirep20221836

Abstract:
Background: Health literacy is a multidimensional concept to promote and maintain of health in the community. Students of the medical sciences are considered as a promoter of health in the society and the evidence regarding health literacy in these students is limited, so the purpose of this study was to determine and compare the students' health literacy in two faculties of Ardabil university of medical sciences in Iran. Methods: This is a descriptive cross-sectional study. A total of 280 students of the Pardis and health schools were randomly sampled and examined. Data collection tool was a native standard questionnaire (HELIA). Data analysis was performed using descriptive statistics. The data was examined using statistical software (SPSS version 20). Results: The results of this study showed that the level of health literacy in Pardis students was significantly higher than students of the health faculty (p=0.000). There was a significant increase in the level of students' health literacy with the increase of academic years in the fields of medicine, dentistry and pharmacy (p=0.009). There was no significant relationship between health literacy levels with field of study, gender, marital status and family income in both groups. Conclusions: The findings of this study indicate that the Pardis students (in medicine, dentistry and pharmacy fields) had sufficient health literacy and had a higher average than health students. In contrast, the health literacy of health students was assessed as insufficient. Given that medical students are the providers of future health care, it is recommended that the authorities do more to promote their health literacy.
Sandeep Shrestha, Shova Maharjan, Anup Dhungana
International Journal of Scientific Reports, Volume 8, pp 246-248; https://doi.org/10.18203/issn.2454-2156.intjscirep20221841

Abstract:
Ossification of laryngeal cartilages usually begins at the age of 20 years in males and at the age of 22 years in females. Ossification in the cricoid cartilage begins from behind to forward. Oesophagus is one of the most common sites for the foreign body. The most common cause of impaction in adults is a meat bolus. A case of 37 years female presented with feeling of pricking sensation in the throat after eating chicken meat which was associated with difficulty in deglutition. X-ray of the neck in antero-posterior view and lateral view was done which showed radio-opaque shadow in front of C6 vertebrae. Rigid oesophagoscopy under general anesthesia was done based on clinical and radiological findings. On rigid oesophagoscopy, foreign body was not seen except minimal injury on the mucosal wall which was 15 cm from the upper incisors. What we can conclude from our case is that, it is always better to confirm a diagnosis of suspected foreign oesophagus with a CT-Scan or Upper GI endoscopy if available to avoid an unnecessary interventions and suffering of patients.
Ghanshyam Rakhecha, Raju Ram Parihar, Aksa Grace Shajan
International Journal of Scientific Reports, Volume 8, pp 243-245; https://doi.org/10.18203/issn.2454-2156.intjscirep20221840

Abstract:
Guillain-Barré syndrome (GBS) is an acute polyneuropathy characterised by varying degrees of weakness that peaks in 4 weeks. We were presenting a case of men of 35 year of age, who had tingling sensation in lover limb (right>left), which was gradually extended, imbalance walking, unable to stand from squatting position and respiratory weakness. The patient took treatment at local hospitals and refer to KEM hospital, where he was diagnosed with GBS syndrome by diagnostic test. He was administered with medication and intravenous immunoglobulin.
Mosopefoluwa A. John, Evans C. Oleka
International Journal of Scientific Reports, Volume 8, pp 221-230; https://doi.org/10.18203/issn.2454-2156.intjscirep20221842

Abstract:
Throughout history, natural products have been utilized to treat a variety of diseases; cinchona tree containing quinine to treat malaria, penicillin for the treatment of infectious diseases, and a wide variety of others. Since the discovery of penicillin by Fleming in 1929, a large number of antibacterial agents have been developed and have had a huge impact on human health. However, due to widespread excessive dispensing of antibiotics, certain bacterial pathogens have developed resistant strains via various mutations in their genomic setup. One of such pathogens is Mycobacterium tuberculosis, hence the study. This study aims at describing the epidemiology of resistant strains of Mycobacterium tuberculosis, its risk factors and potential control strategies in Sub-Saharan Africa. PubMed, BMC and other reliable databases were searched for English research articles published from January 2015 to December 2020 reporting on the molecular epidemiology of Mycobacterium tuberculosis. Due to lack of credible data from all Sub-Saharan African countries and first-line drugs, the study was streamlined to the most populous countries in Sub-Saharan Africa, 17 of which were considered in this study, and the two most common first-line drugs (i.e., Rifampicin and Isoniazid). A total of 54 research articles were thoroughly reviewed for the final analysis. Isoniazid had higher monoresistance (8.5%) than Rifampicin (3.6%). Tuberculosis (TB) Monoresistance was highest in Morocco (54%) and lowest in Mali (4.2%), while multidrug resistance highest in Senegal (58.1%), and lowest in Cameroon (1.1%).
Anwar Rahali, Rahal Mssrouri, Hamid Mohamed, Jalil Mdaghri, Khalid Lahlou, Said Benamr, Abdellatif Settaf
International Journal of Scientific Reports, Volume 8, pp 236-239; https://doi.org/10.18203/issn.2454-2156.intjscirep20221838

Abstract:
The nonrecurrent inferior laryngeal nerve (NRILN), a rare variant in the course of the inferior laryngeal nerve, passes transversely into larynx directly arising from the vagus nerve that increases the risk of damage to the nerve during thyroid and parathyroid surgery. We discussed clinical significance of non-recurrent laryngeal nerve during cervicotomy. Its importance was demonstrated in three clinical cases as well as the related literature reviews. All patients underwent bilateral thyroidectomy for a multinodular goiter. Two patients had identification of the NRILN on the right side. The third patient had the NRILN on the left side. The diagnosis of this anatomical variation was made per-operatively on all cases. The NRILN is an exceptional anomaly but overlooking its risk may lead to grave morbidity. This is a supplementary proof in favour of systematic dissection of the recurrent inferior laryngeal nerve (RILN) during all thyroid and parathyroid surgery.
Rufaida Mazahir, Neha Kumari, Shahzad Alam, Rupa Singh
International Journal of Scientific Reports, Volume 8, pp 240-242; https://doi.org/10.18203/issn.2454-2156.intjscirep20221839

Abstract:
Neonatal thrombocytopenia is one of the common haematological problems encountered in neonatal intensive care unit. Severe neonatal thrombocytopenia is defined as a platelet count <50×103/µl and is relatively uncommon. Based on the time-of-onset, neonatal thrombocytopenia can be categorized into early-onset (72 h after birth) thrombocytopenia. Neonatal autoimmune thrombocytopenia should be considered in any neonate who has early-onset thrombocytopenia and a maternal history of either immune thrombocytopenia (ITP) or an autoimmune disease (with or without thrombocytopenia). A term male baby, born to a 23-year-old primi-gravida with ITP was found to be thrombocytopenic at birth (platelets-85×103/µl) without any sign of neonatal sepsis. On serial monitoring, platelet counts kept falling and on day 3, the child developed severe thrombocytopenia (platelets-6.5×103/µl). No obvious signs of bleeding were present and the child was clinically well. Given the history of maternal thrombocytopenia (likely ITP), a possibility of neonatal autoimmune thrombocytopenia was considered. Owing to the risk of massive bleed, the baby was transfused random donor platelets and intravenous immunoglobulin (IVIg) was started on day 3. Thereafter, the platelets showed an increasing trend and child was discharged on day 7 with a platelet count of 170×103/µl. However, on follow-up platelet count was again found to be low (84×103/µl). It normalised subsequently, without any further requirement of IVIg. High index of suspicion, immediate work-up and diagnosis, with close monitoring and prompt management is required to prevent hemorrhagic complications in such children. Counselling for risk of thrombocytopenia in future pregnancies should be provided to parents.
Chuks Luke Anyanwu, Uwaifoh Akpamu, Moses Odion Eromosele, Osakpolor Glad Odia
International Journal of Scientific Reports, Volume 8, pp 208-214; https://doi.org/10.18203/issn.2454-2156.intjscirep20221835

Abstract:
Background: The aim of this study is to evaluate digito-palmer print among diabetic patients visiting Irrua specialist teaching hospital (ISTH), Irrua Edo State, Nigeria. Methods: Using standard procedures of the ink method, the finger prints of both hands were obtained and palm photographed were taken from clinically diagnosed diabetic patients. The data were analyzed using SPSS (version 21) and results presented in tables. Results: The mean age of the patients was 59.64±9.73 years with 64% females. In the right hand the arch finger print was prevalent on the thumb and loop on the little, middle and ring fingers. In the left hand, the arch print was prevalent on the thumb, index and middle fingers. There was no significance between gender on the distribution of the various finger print patterns except in the right middle finger where females were significantly more likely (p<0.05) to present the loop finger print. The 310-palm print was prevalent in the right and left hands of the diabetic patients with 60% chances of symmetric. Female subjects were more likely to present the 310-palm print compare with male in both hands. The 311 point of origin, intercept and cross (PIC) was absent in the right palm of the male and absent on the left palm of the female. Conclusions: It appears that there exists a variation in the dermatoglyphic patterns in diabetic patients. However, there is a need for larger population-based studies to standardize the parameters and translate the findings into clinical and public health practice.
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