ISSN / EISSN : 2413-1032 / 2414-6404
Published by: RS Global Sp. z O.O. (10.31435)
Total articles ≅ 721
Latest articles in this journal
World Science; doi:10.31435/rsglobal_ws/30062021/7616
Bone damage in fractures is never isolated and is always accompanied by soft tissue damage, microcirculation and neurotrophic processes. The severity of these disorders depends on a number of factors: the mechanism of injury, type and location of the fracture, the magnitude of the displacement of the fragments, the size of the hematoma in the fracture area.One analyzed the rehabilitation treatment after closed osteosynthesis of the tibia in 53 patients with fractures and their consequences (nonhealing fractures, pseudoarthrosis) that were operated with the use of blocking intramedullary metal polymeric fixation devices BIMPF – 3M and BIMPF – 8. No infectious complication was noted, one patient was characterized by a delayed consolidation of fragments in case of closed BIMPO. The average terms of fragments consolidation with a complete restoration of an operated extremity ranged from 10 to 12 weeks in case of dynamic version of BIMPO and 13 – 15 weeks with a static one.
World Science; doi:10.31435/rsglobal_ws/30052021/7590
Мета: виявити рівень фізичного розвитку і загальної фізичної підготовленості важкоатлетів 10-12 років. Матеріали і методи: У даному дослідженні брали участь юнаки 10-12 років які займаються в секціях важкою атлетикою в ДЮСШ ХТЗ, а також в спортивному інтернаті №2 міста Харкова. До експерименту було залучено 25 юнаків які займаються важкою атлетикою. Результати: встановлено, що юні важкоатлети які були задіяні протягом 2-х етапів педагогічного експерименту 1 етап (10 - 11 років), 2 етап (11 - 12 років) - дані. Виявлені відмінності в інтенсивності приросту показників фізичного розвитку за дворічний період спостережень відбивають нерівномірність і гетерохронность дозрівання організму дітей. Навіть за такий відносно короткий проміжок часу (два роки) відзначається помітна різниця в інтенсивності приросту більшості досліджуваних показників фізичного розвитку. Висновки: встановлено, що абсолютні значеня спеціальної фізичної працездатності випробуваних, підвищується на протязі всього дворічного періоду. Однак величина відносної інтенсивності приросту абсолютних значень спеціальної фізичної працездатності на етапах спостережень різна: перший рік - 10,48%, другий - 0,86% (р <0,01). Іншими словами, за перший рік спостережень (вік 10-11 років) показники спеціальної фізичної працездатності значно зростають, а за другий рік (вік 11-12 років) практично не змінюються.
World Science; doi:10.31435/rsglobal_ws/30052021/7589
According to statistics, every fifth married couple has problems with pregnancy. It is known that among all the factors of infertility, the first place is occupied by the tubal-peritoneal factor, and the most common cause of non-pregnancy is a violation of the receptive ability of the endometrium. In the study of the endometrium in patients with unsuccessful attempts at assisted reproductive technologies and severe endometrial insufficiency, there are changes in receptivity, impaired development of foaming, decreased expression of implantation molecules. The development of new methods for correcting the receptive function of the endometrium remains an important step. It should be noted that currently there are no standardized approaches to pre-pregnancy preparation of endometrial receptivity with pronounced signs of lag. Also today, special attention is paid to the impact of carbohydrate metabolism disorders on women's reproductive health. Based on the analysis of literature data and the results of their own retrospective observations, the team of authors identified the role of disorders of carbohydrate metabolism and autoimmunization with food allergens in the violation of endometrial receptivity. It is noted that severe endometrial insufficiency is significantly correlated with an increase in the number of women with disorders of carbohydrate metabolism. The initial algorithm of preliminary preparation of the endometrium of normal immune systems and carbohydrate conversion of heirs in accordance with the mode of processing and analysis is developed and offered. Created, adherence to the elimination diet increases the receptivity of the endometrium with a collection of women according to standard schemes. The proposed training algorithm also improves the overall health of patients, reduces metabolic manifestations.The results of the studies indicate the need for a differentiated approach to the correction of endometrial receptivity and pre-pregnancy preparation of the endometrium before subsequent cycles of ART.
World Science; doi:10.31435/rsglobal_ws/30052021/7588
Disorders in the system of neurohumoral regulation, gastrointestinal peptide hormones, such as cholecystokinin-pancreozymin (CCK-PZ), which also acts as a neurotransmitter, are of great importance in the development of the biliary tract pathology. The influence of CCK-PZ on the gallbladder function in patients with chronic acalculous cholecystitis in combination with non-alcoholic fatty liver disease (NAFLD) and Stable ischemic heart disease (SIHD) remains unexplored.We have examined 60 patients with chronic acalculous cholecystitis, among which patients with concomitant NAFLD and SIHD or without comorbidity were distinguished. The lipid spectrum of the blood was determined for all patients, the level of CCK-PZ in the blood serum was determined by the enzyme immunoassay using reagents made by Peninsula Laboratories Inc (USA). A polypositional ultrasound examination of the gallbladder was performed, as well as a fractional multiple moment duodenal intubation. It was found that the combination of chronic acalculous cholecystitis with NAFLD and SIHD is manifested by a significant violation of lipid metabolism, dyslipidemia, an increase in cholesterol of proatherogenic lipoprotein fractions and a deficiency of high density lipoproteins. A decrease in the level of cholecystokinin-pancreosimin in patients with chronic acalculous cholecystitis leads to a decrease in the contractility of the gallbladder and an increase in the tone of the sphincter of Oddi. An increase in the level of triacylglycerols and total cholesterol leads to an increase in the flow of lipids into the wall of the gallbladder, which is manifested by its thickening and hypotension of the gallbladder.
World Science; doi:10.31435/rsglobal_ws/30052021/7586
В роботі запропоновано, на основі методу прецедентів, концептуальну модель прецедентного формування портфеля постачальників логістичних послуг в проектах формування і реалізації стратегії логістичного аутсорсингу, яка розглядається як стратегія, яка розвивається. Дана модель може бути покладена в основу розроблення методологічних аспектів управління змістом зазначених проектів.
World Science; doi:10.31435/rsglobal_ws/30052021/7587
Aim of study: to determine the pathogenetic factors that have an impact on the development of diabetic myopathy in children with DM1, to investigate the structure of the factors. The observation group included 136 children 14.3 ± 0.3 years old who have been suffering from DM1 for 1 to 10 years. Diagnosed diabetic myopathy in 45 (33.1%) patients (19 (24.4%) boys and 25 (44.8%) girls). By factor analysis, 5 factors were identified that are of leading importance in the pathogenesis of the development of diabetic myopathy in children with DM1. These factors accounted for 73.33% of the total dispersion. The first rank place was represented by the group factor (nitrotyrosine and homocysteine), which accounted for 19.54% of the total dispersion; interpreted as a factor of "oxidative stress". The second rank place was represented by the content of triglyceride in the blood serum and the level of the triglyceride-glucose complex, which amounted to 16.69% of the total dispersion; interpreted as "insulin resistance factor". The third rank place was interpreted as "the state of peripheral blood supply", which accounted for 13.93% of the total variance, and included the indicators of the ankle-brachial index before and after exercise stress. The fourth rank place was interpreted as an "anamnestic factor", which accounted for 12.04% of the total dispersion, and included three risk factors: age, sex of the patient, and duration of DM1. The fifth factor ("inflammation factor") included the indicators of glycosylated hemoglobin and interleukin-6, and demonstrates the development of chronic low-level inflammation against the background of hyperglycemia. Thus, using factor analysis, we determined that oxidative stress, insulin resistance, impaired peripheral circulation, duration of diabetes mellitus, female sex, chronic hyperglycemia, increased activity of proinflammatory cytokines had a priority effect on the pathogenesis of diabetic myopathy. We have formed a factorial model that will optimize the diagnosis of diabetic myopathy, improve approaches to its therapy and prevention, identifying among children with DM1 the risk group for the development and progression of this complication.
World Science; doi:10.31435/rsglobal_ws/30052021/7585
The article presents the prospects for the production and application of carbon-containing nanomaterials used in nanotechnology. These materials include graphene, carbon nanoparticles, and fullerenes. They can be, used, as dielectric, semiconducting, conductive, including superconducting materials. The article also expressed an opinion on the method of obtaining fullerene.
World Science; doi:10.31435/rsglobal_ws/30042021/7538
The rate of infertility in married couples of reproductive age in this country makes up from 10 to 15%, in some regions this value is close to 20% - acritical level that has a negative impact on demographic figures. The rate of pregnancy depends directly on the women’s age and decreases by 3.3times starting from the age of 19 and by the age of 48. The decrease in the ability to conceive is accounted for by subtle mechanisms related to thedeterioration of the quality of oocytes. The patients who are prepared for an extracorporeal fertilization program (ECF) and do not respond tocontrolled ovarian hyperstimulation protocols are considered to be poor respondents. Many studies focused on the development of an optimaltreatment method. However, none of the approaches seems to be effective enough to guarantee a successful use. Platelet-rich plasma is a new andpromising method that is successfully used in the reproductive science to solve a number of medical problems. All the patients whose commonfeatures were low oocyte output and poor embryo quality as well as failed ECF attempts were offered a treatment method of autologous PRP therapyafter their written consent. Three months later, one obtained astonishing results, which by the markers of biochemical infertility alone could beclassified as a complete biological phenomenon and are also characterized by improved embryo quality. The results of hormonal homeostasis show adecrease in the level of the follicle-stimulating hormone by 67.33% while the level of the anti-muellerian hormone is 75.18% higher.Thus, the use of the PRP therapy in poor respondents helps them to overcome their problematic reproductive barrier.
World Science; doi:10.31435/rsglobal_ws/30042021/7542
Tourism has a range of impacts on mountain ecosystems, communities and economies. Many of these impacts are negative, but tourism may also generate positive impacts. They can become supportive force for maintaining peace, fostering pride and cultural traditions, creating local jobs, increasing visitor awareness of natural, cultural and historical values and assets. Local communities and businesses support the long-termsustainability of a tourism destination. A decrease in cultural diversity or authenticity and loss of local customs and traditions may bring the destination to the loss of the attractiveness to visitors seeking a unique cultural experience and attractiveness. In one of the mountain regions of Georgia – Svaneti - the economic benefits of tourism are channeled into the local economy of the region i.e. local community benefit from tourism activities and local businesses (accommodation, transport, food and beverages outlets, souvenirs and crafts etc.) contribute to the authentic nature of the particular mountain destination. Cross-cultural awareness, communication between visitors and local people raises the quality of visitor experience and the level of community understanding in support of tourism.
World Science; doi:10.31435/rsglobal_ws/30042021/7540
Malocclusions that have not been eliminated in time can cause complications such as periodontal diseases, TMJ and muscle dysfunctions.An objective indicator of functional disorders is the change of bioelectrical activity of masticatory muscles. The aim of our study was to estimate thefunctional state of maxillodental system in order to develop the individualized treatment and achievement of high functional and aestheticoptimum in patients with associated occlusal abnormalities who need complex treatment. All examined patients had deviations of the averageamplitude of bioelectrical activity of muscles, asymmetry in muscle function, bursts of spontaneous bioelectrical activity at rest, chewing cyclefragmentations, changes in rest and activity ratio during chewing. One of the most important criteria for the transition to the next stage of treatment isnormalization of bioelectrical activity of the muscles. Such approach allows to achieve stable and long-lasting functional results of the treatment.