Periodontal disease affects patient's health worsening people's quality of life. This clinical case reports the treatment of a 45 years old patient with periodontitis including open flap debridement in first and fourth quadrant and laser treatment on second quadrant

Peripheral nerve surgery involves suturing an injured nerve to itself or to another nerve end-to-end or side-to-end to promote regeneration of the damaged nerve. Nerve surgeries include repair, grafting, transfer, and decompression

Etinal degenerative diseases, such as Stargardt’s Disease (SD), glaucoma, Retinitis Pigmentosa (RP), Age-Related Macular Degeneration (AMD) or Diabetic Retinopathy (DR), represent the main causes of a decreased quality of vision and blindness worldwide. The progression and management of these conditions have always represented a challenge, but promising new evidences about the efficacy of Mesenchymal Stem Cells (MSCs) as therapy for these diseases has been shown

The impact of inflammatory environments on the impaired features of MSCs, such as loss of homeostasis and stem cell senescence, still remains unclear. In the paper titled “MIT-001 Restores Human Placenta-Derived Mesenchymal Stem Cells by Enhancing Mitochondrial Quiescence and Cytoskeletal Organization”, Yu et al., investigated the phenotypes of MSCs exposed to pro-inflammatory cytokines TNF-α and IFN-γ. They further tested whether the exposed MSCs are protected from senescence by MIT-001, a novel necrosis inhibitor and an anti-inflammatory molecule

Equine multipotent mesenchymal stem cells (hrs-MSC) can be isolated from various tissues including Adipose Tissue (AT) and Umbilical Cord Blood (UCB). We have analyzed the effect of different oxygen tension on hrs-AT-MSC and hrs-UCB-MSC cultured and assessed proliferation, morphology, viability and immunophenotype and plasticity. Both type of equine MSC were cultured separately in normoxic (21% O2) and hypoxic (5% O2) environment

Microgravity and the space environment have significant impact on the physiology of organisms. Understanding the responses elicited in the Central Nervous System (CNS) such as alteration in the visual function process and the regulation of biological pathways leading to changes of the CNS function, is critical to design contra measures aiming to mitigate the impact on astronaut’s health

The purpose of this clinical case report is to describe a full-arch rehabilitation with one to one endosseous implant restoration. Although the proposed treatment may not be within the financial means of most patients, the aesthetical result is higher because of the close similarity between the final restorations and the natural dentition.

Alzheimer’s disease is the most prevalent neurodegenerative disorder in the elderly population. The patients suffer cerebral atrophyas a consequence of extensive neuronal loss, especially in areas that play a role in memory and cognition. Cell therapies approaches have emerged as promising treatments to regenerate the brain tissue of the patients

Sensorineural Hearing Loss (SNHL) continues to be a significant public health problem with over 270 million affected people worldwide and an incidence that increases with age [1,2]. Some cases of SNHL have a genetic cause, but the majority of SHNL is the result of ototoxic insult [3]

Osteoarthritis (OA) is Degenerative Joint Disease (DJD) associated with pain, inflammation and cartilage degradation resulting in lameness. This state is irreversible and actual conventional therapies are not able to provide regeneration of damaged tissue. Current therapies, mainly NSAIDs, have many adverse effects and are not able to stop degenerative process