Clinical Studies and Medical Case Reports

Journal Information
EISSN : 2378-8801
Published by: Herald Scholarly Open Access (10.24966)
Total articles ≅ 106
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Saccomanni Bernardino, Bari Viale Regina Margherita
Clinical Studies and Medical Case Reports, Volume 8, pp 1-2; https://doi.org/10.24966/csmc-8801/1000122

Abstract:
Mesenchymal Hamartoma is a rare, benign osseous tumor that typically involves the rib cage and presents during the first year of life. There is a case of this tumor originating in the cervical spine, described in literature. I document a brief literature review. In this review, there are not figures and outcomes.
, Unidade Local De Saúde Do Baixo Alentejo
Clinical Studies and Medical Case Reports, Volume 8, pp 1-2; https://doi.org/10.24966/csmc-8801/1000123

Abstract:
Neonatal mastitis is an inflammatory process of the mammary gland, presenting as erythema, edema, hypersensitivity, induration, sometimes with purulent exudate or abscess. It occurs more frequently in female infants, in the 3rd week of life and is usually unilateral. In most cases, the agent involved is Staphylococcus aureus and the clinical evolution is favorable.
, Tzaneio General Hospital Of Piraeus
Clinical Studies and Medical Case Reports, Volume 8, pp 1-3; https://doi.org/10.24966/csmc-8801/100116

Abstract:
We report a case of celiac crisis in a previously healthy 51-year-old female presenting with a month’s history of diarrhea, cachexia and an abnormal metabolic panel.The patient’s diarrhea resolved after initiation of a gluten free diet and she gained 4 kilograms during hospitalization. Celiac crisis is a very rare presentation of celiac disease in adults but nonetheless should be considered in patients with marked metabolic derangements in the setting of osmotic diarrhea.
, University Of Cape Coast
Clinical Studies and Medical Case Reports, Volume 8, pp 1-4; https://doi.org/10.24966/csmc-8801/1000125

Abstract:
Introduction: Abdominal pregnancy is a rare form of ectopic pregnancy with very high feto-maternal morbidity and mortality. Diagnosis and management can pose difficulties in low-resource centres. High index of suspicion is vital in making a prompt diagnosis. Case Presentation: A 23year old, gravida 2, para 1, who presented with a two-day history of severe abdominal pain was referred from a satellite clinic. Abdominal ultrasound scan revealed a live 18week 5day intra-abdominal pregnancy. Emergency laparotomy showed an intact gestational sac at the superior aspect of the uterus with massive hemoperitoneum. The placenta was attached to the right ovary, omentum, and fimbriae of the right fallopian tube. Conclusion: Abdominal pregnancy is a rare occurrence and requires a high index of suspicion for prompt diagnosis. Massive hemoperitoneum can be life threatening and prompt surgical intervention is key in saving the life of the mother.
, University Of California San Diego
Clinical Studies and Medical Case Reports, Volume 8, pp 1-4; https://doi.org/10.24966/csmc-8801/1000119

Abstract:
A 14-year-old female presented for congestive heart failure with biventricular hypertrophy and severely depressed LVEF. Cardiac MRI findings of extensive LGE but sparing the mid septum, genetic tests reporting a LAMP2 missense mutation and LAMP2 protein staining in the minority of cardiac myocytesat immunohistochemistry suggested a Danon Disease diagnosis.
Igor Smirnov, Global Quantech Sia
Clinical Studies and Medical Case Reports, Volume 7, pp 1-9; https://doi.org/10.24966/csmc-8801/100087

Abstract:
We found the significant protective properties of MRET water confirmed by substantial decrease of Staphylococcus aureus CFU (colony forming units) in homogenate of kidneys of mice on MRET water compared to control group of mice on regular water following the intra-peritoneal staphylococcal infection. Another study relates to a detailed observation of the effect of MRET activated water with the modified molecular structure, physical and electrodynamic characteristics on metabolic activity and growth of conditionally pathogenic microbiological culture Escherichia coli K-12 (E.coli) and on metabolic activity of microbial associations (similar to microbial associations in the intestine). Activated (MRET) water produced significant changes of E.coli morphology: different shape, color and size of cells, disturbance of process of cellular division. We also observed positive results of MRET water complimentary treatment for HIV patients during the clinical trial. There are recent research data which allows pointing to a similar mode of action for the two viral proteins, suggesting that anti-viral strategy that targets the viral-induced membrane fusion step can be adapted from HIV-1 to SARS-CoV. The stability of virus spike protein structure is based on the overall interactions of van der Walls weak electrodynamic forces and hydrogen bonding. It is obvious, that all biochemical formations of proteins require presence of water molecules in biological systems. The overall observed research data suggest that modification of water - based medium electrodynamic parameters of the human tissues (that are favourable for the homeostasis of the body in the range of physiological “window”) can lead to significant change of van der Walls interactions and hydrogen bonding that result in the inhibition and interruption of virus spike proteins formation. Such scenario obviously disables virus life sequence of attachment and fusion with human cell membranes. The same type of mechanism can be adopted for the inhibition of other lines of pathogenic microorganisms. The studies conducted at AltheaDx Technology, USA confirm that MRET activated water based medium did not affect the morphology of normal PBMC cells on genetic level; it affected the morphology of normal PBMC cells in a positive way increasing their viability. MRET Activated Water is produced with the help of patented in the USA Molecular Resonance Effect Technology (MRET, US Patent # 6022479). We suggest that MRET water consumption by human subjects can lead to physiologically favorable modification of dielectric permittivity and hydrogen bonding of water –based medium in the human body tissues. It can provide the initial human body natural defence against intervention and spread of pathogenic microorganisms
, Barzilai University Medical Center
Clinical Studies and Medical Case Reports, Volume 7, pp 1-6; https://doi.org/10.24966/csmc-8801/100091

Abstract:
Background: Imaging techniques used in the last decades, and reported changes in various disease prevalence, may have dramatically influenced causes of Fever of Unknown Origin (FUO) Objectives: Our study’s objectives were to identify changes in prevalence and etiologies of FUO, since our previous study two decades ago, to clarify the most beneficial diagnostic strategies, and to investigate the long-term outcomes of undiagnosed and diagnosed patients Methods: Medical files with “fever” as a cause for admission and at least one-week hospitalization were evaluated. Patients were screened based on Petersdorf’s classic criteria. An interview was performed three months to twelve years after hospitalization Results: 3691 patients fit our primary selection criteria in 2004-2016; 141 patients fit Petersdorf’s criteria for FUO. The most common cause of FUO was infectious disease (39%), mainly bacterial (29%), though decreased from our previous study (39% vs 55%). There were dramatic increases in the incidence of malignancy (19% vs 7.9%) and inflammatory (20% vs 2%) etiologies and less undiagnosed cases (22% vs 32.7%). Weakness and weight loss were the most common co-complaints (80% all coexisted). Elevated ESR (97%), elevated CRP (95%) and anemia (80%), were the most common pathologic laboratory examinations found. Abdominal CT, blood cultures and serology proved to be the most valuable diagnostic tests. Long-term follow up interviews revealed that a final diagnosis was often reached during the patients’ next admission (20% out of 70%). 2% of patients died during the feverish episode and 34% died three months to twelve years after the episode Conclusions: Infections (mainly bacterial) remain the most common cause for FUO in southern Israel in the 21th century; although there is a remarkable increase in the rate of vasculitis and malignancy. When PET is not available, a thorough clinical examination including appropriate laboratory and imagine examination, as well as precise history taking are essential. Blood cultures and abdominal CT are the most useful diagnostic tests. Most undiagnosed cases resolved within days of discharge or are diagnosed in a following admission
Clinical Studies and Medical Case Reports, Volume 8, pp 1-5; https://doi.org/10.24966/csmc-8801/1000113

Abstract:
Introduction: The aetiology of conversion disorder is unknown, though association with emotional stress and with organic brain disorder has been described. Paraplegia as a conversion reaction has been reported infrequently. Combination of motor and sensory disturbance, other than paraplegia, may occur as a manifestation of a conversion reaction, and may suggest Spinal Cord Injury (SCI). Case Report: A 35-year-old Italian woman who had a history of post traumatic SCI which affected her lower limb when she was 29 years old. Patient was unable to empty his bladder completely.The aim of this paper is to describe the correlation between diagnosis of conversion disease and SCI. Clinical Rehabilitation Impact: Chronic conversion disorder can be resistant to rehabilitation treatment. Neurophysiological diagnostic procedures adopted in our study discern the degree of central and peripheral nervous system damage and confirmed the integrity of spinal cord in conversion disorder. Conclusion: Our case report describes the association between conversion disease, SCI, and neurophysiological tests and suggests to apply the neurophysiological tests to validate conversion disorder diagnosis in SCI.
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