Dental Oral Biology and Craniofacial Research

Journal Information
ISSN / EISSN : 2613-4950 / 2613-4950
Published by: Science Repository OU (10.31487)
Total articles ≅ 62
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Gustavo Moncada, Gabriela Díaz Mujica, Constanza Valdés
Dental Oral Biology and Craniofacial Research, Volume 2022, pp 1-10; https://doi.org/10.31487/j.dobcr.2022.03.01

Abstract:
Objective: Evaluate the evidence of the clinical correlation between vitamin D and symptomatic degenerative joint disease. Methods: A systematic search and meta-analysis was conducted of randomized controlled studies (RCTs) published in between January 1st, 2010, and March 30th, 2020 on five different databases. The study population consisted of adult patients with symptomatic knee osteoarthritis; the intervention was vitamin D; the comparison was placebo, and the outcomes included the Western Ontario and McMaster Universities Arthritis Index (WOMAC) (pain, function, stiffness), tibial cartilage volume, synovial tissue volume (STV), subchondral bone marrow lesion (BML) volume, effusion-synovitis, serum vitamin D3 levels, serological inflammatory and metabolic biomarkers levels and adverse events. Results: Nine RCTs involving 2,168 patients were included in this study. Pooled estimates suggested that vitamin D supplementation was associated with reduction in WOMAC pain (Std. Mean=1.08(0.90, 1.25); I2=99%; p=0.00001), function (Mean=1.1(0.92, 1.27); I2=99%; p=0.00001), stiffness (Std. mean= 0.72(0.54, 0.90); I2=98%; p=0.00001) and synovial effusion in the suprapatellar pouch numbers. There was no significant difference in tibial cartilage volume incidence (Std. Mean=0.26(0.44, 0.80); I2=99%; p=0.00001), STV, BML volume, inflammatory biomarkers and adverse events between the vitamin D and the placebo groups. Conclusion: Vitamin D supplementation was effective in improving WOMAC pain and function in patients with knee OA and also improved serological vitamin D levels. However, it had no beneficial effect on structural cartilage change or inflammatory biomarker reduction. Therefore, there is currently a lack of evidence on vitamin D regimen dosage and length to obtain benefits in preventing knee disease progression.
Shrishtee Goyal, Narayan B. Kulakrni
Dental Oral Biology and Craniofacial Research, Volume 2022, pp 1-8; https://doi.org/10.31487/j.dobcr.2022.02.01

Abstract:
Introduction: Introduction of digital technology in orthodontics has improved the overall experience for the patient as well as the clinician. This study aimed to assess knowledge, attitude and practice of digital orthodontics among orthodontists and orthodontic residents in Gujarat through a questionnaire. Materials and Methods: The questionnaire comprised of two parts, the first part which consisted of sociodemographic details (5 questions) and the second part consisted of questions to assess the knowledge (2 questions), attitude (9 questions) and practice (3 questions) of digital orthodontics. The final developed questionnaire after content validity was sent to Orthodontists and Orthodontic residents as Google Form link to Gujrat Orthodontic Study Group over WhatsApp and the received responses were recorded. Results: Kolmogorov- Smirnov test was employed to test the normality of data. Chi Square test was performed for the quantitative variables. Results showed that majority of the participants knew about availability of digital orthodontics. Revealed a positive incline in incorporating digital orthodontics in their routine practice. However, a lack was observed in practicing digital orthodontics among Orthodontists and Orthodontic Residents of Gujarat Statistically significant difference was present regarding the awareness about digital orthodontics between males and females (p value = 0.042). Conclusion: Orthodontists and orthodontic residents of Gujarat displayed adequate knowledge, positive attitude and lack of practice about digital orthodontics. Male population is more aware about digital technologies as compared to female population.
Alexander Faigen, J James, M Stevens, S Looney, A Jenzer, T Johnson
Dental Oral Biology and Craniofacial Research, Volume 2022, pp 1-13; https://doi.org/10.31487/j.dobcr.2022.01.02

Abstract:
Introduction: The purpose of this study was to evaluate the factors which had the greatest impact on implant cervical bone health. A retrospective review was completed, and various factors were examined. The investigators hypothesized that there is no difference in implant success based on location, brand, or length of the implant. Methods: A retrospective electronic chart review of patients from the Dental College of Georgia (DCG) was done, looking at a study population composed of all patients who had an implant placed between January 1, 2009, and January 1, 2010. This included any type of dental implant placed at this academic institution, within any of the multiple departments who place implants. Patients were excluded as study subjects if they had the implant placed by another practitioner outside of the DCG. Information including location, brand, timing, age, sex, and complications was examined. Results: The sample was composed of data extracted from the dental records of 67 eligible study participants. Of these, 63 (94%) had data on bone loss and all results in this paper are based on these 63 patients. The majority of the participants were female (42/63, 67%), and age ranged from 41 to 88 (mean 68.6, SD 12.3, median 70). Significantly more bone loss was found in maxillary implants than in mandibular. This was true for mesial (p = 0.013, Table 1), distal (p = 0.012, Table 2), and average bone loss (p = 0.006, Table 3). Conclusion: The results of this study suggest a relation between implant length and positioning and bone loss. Future studies will focus on the development of more clinical markers and assessment tools for failure.
Camille Philip-Alliez, Michel Le Gall, Adele Brotons, Oceane Monachini, Bruno Foti, Floriane Remy
Dental Oral Biology and Craniofacial Research, Volume 2022, pp 1-5; https://doi.org/10.31487/j.dobcr.2022.01.01

Abstract:
Civil age estimation is part of the process of individual identification for judicial purpose. It must be applicable for dead bodies as well as for living persons. Age can be estimated through the analysis of the permanent teeth eruption process. In the present study, this process was analysed based on the Bengston’s revisited stages illustrated by AlQhatani et al. in 2010. They were used to build a linear regression model for age estimation of children. This model was built on a sample composed of 191 orthopantomographs of children aged from 9 to 19.9 years old. The created model allowed the elaboration of a formula for civil age estimation based on the most relevant teeth groups associated to their eruption stages. The estimated age showed a good correlation with civil age (R2: 0.74), and a good accuracy rate (57% at +/- 12 months and 75% at +/- 18 months). Despite what was expected, sex was not correlated with age and was discarded from the analysis.
David Cawthorpe
Dental Oral Biology and Craniofacial Research, Volume 2021, pp 1-6; https://doi.org/10.31487/j.dobcr.2021.03.05

Abstract:
Objective: The study objective was to examine the relationship between dental caries diagnosed before the age of four and ICD diseases over a 16-year period. Methods: The sample of approximately 33,531 (48% female) individuals having a total of 2,864,790 physician diagnoses over 16 years comprised a the cohort two groups, one with (2.7% of the sample) and one without dental caries (dependent variable) that were under the age of four years in the first two years of the sample data. Categories of dental caries and associated gingivitis and periodontal disease were based on the International Classification of Disease (ICD Version 9) diagnostic codes 521-523. The sample was described. Odds ratios comparing those with and without dental caries and the main ICD classes were calculated. Additionally, the ratio of each ICD diagnosis frequency comparing the cohort groups were calculated and represented the diagnoses assigned over the first 15 physician visits. Results: Males had proportionally more dental caries diagnosed. Diagnoses were made predominantly by general practitioners. Within the dental caries cohort group, associated ICD diagnoses were over-represented in both odds ratios and within individual ICD diagnoses on the first diagnosis and over the first 15 diagnoses in time. Conclusion: Dental caries diagnosed in very young children before the age of four are associated with multi-morbidity over subsequent years. Sex differences and patterns of associated morbidity may contribute to a better understanding of early life vulnerability to dental caries and their sequelae.
Andrew Jenzer, Macarius Abdelsayed, Jeffrey James, Kyle B Frazier, Brian Sellers, Rafik Abdelsayed
Dental Oral Biology and Craniofacial Research, Volume 2021, pp 1-3; https://doi.org/10.31487/j.dobcr.2021.04.01

Abstract:
The surgical ciliated cyst is an iatrogenic lesion occurring after surgeries in which the Schneiderian membrane has been exposed, such as in orthognathic surgery or maxillary sinus procedures. This lesion has been infrequently documented in western countries. In this case series, we present three cases of surgical ciliated cysts of the maxilla.
Gurel H.G., Z Novruzov, M Behruzoglu
Dental Oral Biology and Craniofacial Research, Volume 2021, pp 1-6; https://doi.org/10.31487/j.dobcr.2021.03.03

Abstract:
Purpose: The purpose of this study was to compare the outcomes of the treatment with the twin block and modified twin block appliances in growing patients with Class 2 malocclusion. Materials and Methods: A cephalometric analysis was performed in 51 patients. The twin block sample consisted of 23 patients, 10-girls and 13-boys (mean age 10.46±0.71 years at the start of treatment, T1, and 12.84±0.78 years at the end of active treatment, T2). The modified twin block sample consisted of 28 patients, 18 girls and 15 boys (mean age 11.78±0.91 years at T1, and 13.32±0.56 years at T2). The twin block activators were used during the day, except for eating time, and the modified ones were used only at night. Duration of the treatment was 16-20 months. The changes from T2 to T1 and the differences between the groups were compared with the analysis of variance. Results: SNB angle in the twin block group showed 1.25±1.39 degrees change and in the modified twin block group, it exhibited 3.69±1.01 degrees change. Overjet in the group with twin block decreased 4.58±1.59 mm, and in the group with modified twin block it decreased 4.43±1.41 mm. In the modified twin block group, there was more retrusion of upper incisors in comparison with the twin block group. Accordingly, under the effect of modified twin block, retrusion of the upper lip was observed. Conclusion: Through modifying the twin block appliance, it is possible to ensure the comfort of the patients by reducing the daily usage, to reposition the mandibula forward and to correct overjet and sagittal dento-skeletal relationships without increasing facial height and to improve positions of upper incisors and lips.
Lara Pepita De Souza Oliveira, Moises Aleli Gomes, Jefter Haad Ruiz da Silva, Cláudia Cândida Silva, Danielson Guedes Pontes, Diego Ferreira Regalado
Dental Oral Biology and Craniofacial Research, Volume 2021, pp 1-6; https://doi.org/10.31487/j.dobcr.2021.03.04

Abstract:
Direct restorations in composite resin require superficial rugosity appropriate to guarantee a surface free of biofilm buildup, which interferes with the durability of the restoration, its properties and the aesthetic aspect. Thus, it is relevant to know the behaviour of the finishing and polishing systems. The in vitro study aimed to compare the polishing efficiency of three different polishing systems in promoting the surface smoothness of a nanocomposite resin. Sixty specimens of the nanocomposite resin Filtek Z350 XT (3M) were made, randomly divided into three groups (n=20), according to the tested polishing systems: Enhance (Dentsply), DFL Polishers, and Sof-Lex Spiral (3M). The surface rugosity of the samples was measured by means of the rugosimeter equipment. The data were analysed through statistical tests: ANOVA two-way and post-hoc Tukey. The results indicated Sof-Lex (3M) polishing discs as the ones with the lowest average surface rugosity (0.13µm), presenting statistically significant results (p<0.05); followed by the abrasive rubbers of the DFL system (0.17 µm) and the Enhance system (Dentsply), which showed greater average surface rugosity (0.30 µm). The lowest surface rugosity of the composite resin evaluated in this study (Z350 XT- 3M) was obtained after polishing with the multi-step system (Sof-Lex), from the same manufacturer.
Juan Fernando Buestan Zambrano, Maria de Lourdes Rodriguez Coyago
Dental Oral Biology and Craniofacial Research, Volume 2021, pp 1-10; https://doi.org/10.31487/j.dobcr.2021.03.01

Abstract:
Introduction: Ameloblastoma is a benign odontogenic tumor that is aggressive and localised in nature, listed as the first or second most prevalent odontogenic tumor and rarely tends to metastasis, but when it does, it receives the definition adopted by the WHO in 2017 of metastasizing ameloblastoma. Materials and Methods: This systematic review of clinical case reports of metastasizing ameloblastoma from the last 10 years, collected from PubMed, ScienceDirect and Cochrane digital databases, aims to search for association between clinical/pathological and/or molecular parameters of ameloblastoma and its metastatic potential. Results: The targeted search yielded 14 publications with a total of 18 clinical cases, which showed a mean age for diagnosis of metastasizing ameloblastoma of 46 years, with no gender predilection and a high probability of occurrence in the yellow Asian race, favouring a pattern of distant dissemination. The highest frequency of metastasis was associated with mandibular primary lesions diagnosed in young patients, and the most frequently found variant was the multicystic solid type, follicular subtype; distant metastasis was the predominant form of presentation, with the lungs being the main target. Conclusion: At the moment, there is nothing that can predict metastatic potential in ameloblastoma. More standardised studies exploring the molecular terrain are needed, as this is a key and understudied factor.
Mansi Mathur, Nillima Sharma, Mamta Parashar, S K Rasania, S Dwivedi, Mitasha Singh, Sneha Gupta
Dental Oral Biology and Craniofacial Research, Volume 2021, pp 1-7; https://doi.org/10.31487/j.dobcr.2021.02.06

Abstract:
Background: Periodontitis is an extension of inflammation to the supporting tissue of the tooth. Prevalence varies worldwide with a higher prevalence in Asian countries and in India as reported. Literature reports that the sub-gingival microflora and the continuous latent endotoxemia originating from the periodontal pockets is a risk factor for the damage to vascular endothelial integrity, platelet function and blood coagulation leading to periodontal disease playing a role in etiopathogenesis of coronary artery disease and cerebrovascular disease. Aim: To study periodontitis and other risk factor that correlates with CAD among the adult urban population. Settings & Design: Clinic based case control study carried out in medicine and dental outpatient departments (OPD) of Hamdard Institute of Medical Sciences & Research and associated HAH Centenary Hospital, New Delhi. Minimum sample size was calculated to be 140. A 1:3 case to control ratio was taken. Methods & Materials: Periodontal Index (Russell Index) was utilized in our study to grade periodontal health status. Statistical Analysis: The data was analysed using SPSS 21.0 version. Categorical variables were tested for significance using Chi square test and multiple logistic regression was used for predicting the probability of cases with cardiac problems having periodontitis. Results: 30 (21.4%) participants were recruited as cases and 110 (78.6%) as controls. Among the cases the Mean Russell score for case was 3.98 ± 0.70 and control group was 3.11 ± 0.68, respectively. Among the total subjects 76.4% showed a RI score of ≥3 indicative of established destructive and terminal periodontal disease and 23.5% constituted the beginning of destructive periodontal disease. Conclusion: Severity of periodontitis was noted in cases as compared to controls. Findings suggest the relationship between CAD and periodontal disease.
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