Journal of Dr. Behcet Uz Children s Hospital

Journal Information
ISSN / EISSN : 2146-2372 / 1309-9566
Total articles ≅ 436
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Latest articles in this journal

Mehmet Coşkun, Şeyma Akkuş, Şükran Keskin Gözmen, Malik Ergin, Erkin Serdaroğlu, Nida Dinçel
Journal of Dr. Behcet Uz Children s Hospital, Volume 11, pp 23-28;

Objective: The aim of this study was to determine the relationship between number of passes and complications in pediatric native kidney biopsies performed under ultrasonography guidance. Methods: Forty-nine children who underwent native kidney biopsies using a 16 Gauge semi-automatic needle between 03/2019-03/2020 were included in the study. All patients were evaluated with ultrasonography before and after biopsy procedure to detect complication(s). Two or more passes were performed in most cases where electron microscopy was required. Requirement for transfusion or intervention was considered as a major complication. The technical success was calculated considering number of glomeruli harvested. Number of passes were compared with complication rates and number of glomeruli sampled. In statistical analysis, chi-square, t-test, and ANOVA tests were used. Results: Minor, major complications and technical success rates were 36.7%, 0% and 100%, respectively. Number of passes were 1 in 4, 2 in 30, 3 in 11 and 4 in 4 cases. Increasing number of passes were related with higher complication rates (p=0.002). The complication rates were 23.5%, and 66.7% when ≤2, and ≥3 passes were used. Complication rate was higher when ≥3 passes were used (p=0.009), without any increase in the number of glomeruli sampled (p=0.839). Conclusion: Pediatric native kidney biopsy was a safe procedure using 16 Gauge needle under ultrasonography guidance. Three of more passes caused an increase in minor complication rates without any increase in the number of glomeruli sampled.
Inanç Karakoyun, Mustafa Onur Öztan
Journal of Dr. Behcet Uz Children s Hospital, Volume 11, pp 87-93;

Objective: The objective of this research was to evaluate the diagnostic value of mean platelet volume/platelet count (MPV/PC) ratio in pediatric acute appendicitis. Methods: This retrospective study included a total of 310 patients, 176 in the uncomplicated appendicitis group, 80 in the complicated appendicitis group, and 54 in the nonspecific abdominal pain (NSAP) group. C-reactive protein (CRP) level, white blood cell (WBC) count, absolute neutrophil count (ANC), MPV, PC, and MPV/PC ratio were compared between the groups. Results: WBC and ANC levels differed significantly between the groups (P<0.001 in all pairwise comparisons). CRP levels in the complicated appendicitis group were higher than in the NSAP and uncomplicated appendicitis groups (P<0.001 for both comparisons). There was a negative correlation between MPV and PC (r= -0.434, P<0.001). Both PC and MPV/PC ratio were able to distinguish cases of complicated appendicitis from NSAP (P=0.047 and P=0.045, respectively) and from cases of uncomplicated appendicitis (P=0.010 and P=0.045, respectively). Areas under the ROC curve for CRP, WBC, ANC, MPV, PC, and MPV/PC ratio were 0.640, 0.690, 0.727, 0.553, 0.541, and 0.546, respectively. Conclusion: According to the results of our study, MPV/PC ratio can be used in addition to the conventional markers to discriminate cases of complicated appendicitis.
Selcen Kundak, Ayşe Kutlu
Journal of Dr. Behcet Uz Children s Hospital, Volume 11, pp 101-107;

Objective: Alopecia areata (AA); is a sudden onset, non-scaring hair loss. Twenty percent of cases are children.Although it is thought to be related to genetic predisposition, inflammation, immunological processes or psychological triggers, its pathophysiology is still not fully understood. This study was planned to investigate the levels of serum 25-hydroxy vitamin D, vitamin B12, thyroid-stimulating hormone (TSH) and free T4 FT4) in children with AA and compare the results with age-matched healthy individuals. Methods: A retrospective medical record review was carried out in an outpatient dermatology clinic in a tertiary medical center between January 1,2013 and December 31, 2017. The study included 520 patients (ages 0-18 years) who received a clinical diagnosis of AA.106 patients with AA met the inclusion criteria.Patients in the control group (n=106) were selected among children aged 0-18 years without any medical and/or psychiatric diagnosis. Both past medical and family medical history were also noted. Results of laboratory tests including vitamin D, vitamin B12, TSH, FT4, and thyroid auto-antibodies were noted. Results: There was no significant difference between the patient and control groups in terms of mean age.Mean age of onset was 8.0 years. The number of boys and girls in both the patient and control groups were 55 and 51. Serum levels of FT4 and TSH in patients with AA were significantly higher than the control group. Both vitamin D and vitamin B12 levels of the patients with AA were significantly lower than the control group. Conclusion: Although its role in etiopathogenesis is not understood, the importance of monitoring both vitamins and thyroid functions in childhood AA cases is obvious.
Osman Hasan Tahsin Kılıç, Murat Anıl, Merziye Gökçe Göksu, Umut Varol, Güven Güvendi, Bahadır Haytabey, Istemihan Çoban, Berna Dirim Mete
Journal of Dr. Behcet Uz Children s Hospital, Volume 11, pp 57-65;

Objective: The aim of this study is to evaluate the attitudes, behaviors, and beliefs of medical faculty students about the covid-19 pandemic. Methods: Between 29/03/2020 and 04/13/2020 a total of 1,332 students had been questioned in three Turkish speaking countries (Turkey, Azerbaijan, Turkish Republic of Northern Cyprus). Results: The average age of the students were 20.1 ± 1.6. Among all 895 (67.7%) of them were female and 427 (32.3%) were male. 1020 (77.2%) of the studens were in Turkey, 195 (14.8%) were in Azerbaijan and 107 (8.1%) were in the TRNC. 104 of the students (7.9%) had a chronic disease. It was found that number of alcohol and cigarette users decreased significantly during the pandemic. (p <0.001, p <0.001). Anxiety levels of those who quit or reduced smoking were found to be higher than those who increased or did not change their amount of smoking (p=0.034). It was found that the most benefited sources were “their faculty lecturers” (n=453, 34.3%), “Worldometer ® website” (n= 449, 34%) and “Youtube videos” (n=396, 30%). Conclusion: Longitudinal studies are needed on the effects of pandemic on alcohol and tobacco use. It is important to educate future physicians in social media literacy, interpretation and responsibilities for social media posts. In this way, perhaps we can contribute to minimize the public’s erroneous beliefs and maladaptive behaviors regarding the pandemic and reduce stigmatizing attitudes towards physicians, elders and Asians
Müge Ayanoğlu, Hale Tuhan, Ayça Kömüroğlu, Ayşe Tosun
Journal of Dr. Behcet Uz Children s Hospital, Volume 11, pp 73-79;

Objective: Primary headaches are common and benign discomforts both in children and adolescents. However, they have a negative influence on the quality of life. This retrospective study aimed to determine the relationship between vitamin B12 results and primary headaches in Turkish children. Methods: Demographical features, headache types, laboratory results, including vitamin B12, were assessed retrospectively. Headache types were categorized as tension-type headache, migraine, and unclassified headache according to the International Classification of Headache Disorders-beta version (ICD-3 beta). Patients with seconder headaches, anemia, and macrocytosis were excluded. Results: The study group consisted of 133 (86 female, 47 male) patients with headache and a control group of 103 (57 female, 46 male) healthy children. There was no significant difference in terms of age and gender between groups (p>0.05). Vitamin B₁₂ levels in tension-type headache, migraine, and unclassified headache groups were significantly lower (p<0.0001) than in the control group. Logistic regression has identified lower vitamin B12 levels than 400 pg/ml as an independent risk factor for headache (OR: 3.212, 95% CI: 1.850-5.576). Conclusion: We conclude that lower vitamin B12 levels than 400 pg/mL may be associated with tension-type headache, migraine, and unclassified headache.
Birsen Şentürk Pilan, Serpil Erermiş, Tuğçe Özcan, Reyhan Çalışan, Ilayda Barankoğlu, Ahsen Kaya, Ender Şenol, Hülya Güler, Ahmet Acarer, Tezan Bildik
Journal of Dr. Behcet Uz Children s Hospital, Volume 11, pp 123-132;

Objective: The aim of this study was to examine the sociodemographic characteristics, psychiatric diagnoses and factors associated with psychiatric diagnoses of children and adolescents who are victims of sexual abuse. Method: The files of 92 children and adolescents aged between 0-18 who were referred to University Hospital Child and Adolescent Psychiatry Forensic Policlinic between January 2017 and December 2019 due to sexual abuse were evaluated retrospectively. Psychiatric diagnoses of the cases were made according to DSM 5 diagnostic criteria. Intellectual capacity of the cases was evaluated according to the latest verison of Wechsler Intelligence Scale for Children. Results: In our study, 78 (84.8%) cases were female and 14 (15.2%) were male. Mean age of the cases was 14.1±3.88 years. The most common type of sexual abuse was touching (52.2%, n=48). There was a psychiatric diagnose in 50 (54.3%) of them. The most common psychiatric diagnoses were posttraumatic stress disorder (n=29, 31.5%) and major depressive disorder (n=25, 27.2%). The rate of psychiatric diagnosis was significantly higher in cases exposed to coercion and violence (p=0.032). In 32 cases (34.8%), it was determined that the abuser was within the family. Conclusion: Sexual abuse has an effect on child’s development throughout life.In our study, the rate of psychiatric diagnosis was high. It is very important to provide the necessary psychiatric support to the victims of sexual abuse. With the studies to be done in this area, awareness can be increased and necessary precautions can be taken.
Pınar Ayvat
Journal of Dr. Behcet Uz Children s Hospital, Volume 11, pp 159-166;

Objective: Bibliometric analysis can be used to assess the contributions of scholars, institutions, countries by examining the materials published in a certain discipline. The objective of this study is to make a bibliometric analysis in the field of pediatric anesthesia and to examine Turkey’s contribution to research in this field. Methods: I used the search engine of the Web of Science (WoS), and included all types of contributions (original articles, reviews, letters, editorials, etc.) in the bibliometric analysis. I scanned Science Citation Index Expanded (SCIE) and Emerging Sources Citation Index (ESCI) as they were the most relevant indexes for my study. Statistical analyses were performed by using SPSS 22. I used a binomial test to make a comparison between Turkey and other countries in terms of research output, and academic performance. Results: Pediatric Anesthesia is the only journal that positions itself in WoS categories of both “pediatrics” and “anesthesia”. A total of 5,791 citations were found in this particular journal of which 227 were from Turkey. In addition to this journal, 2,096 published materials were found in 433 different sources. Turkish authors have made only 61 contributions to these journals. Hacettepe University, Istanbul University, and Baskent University are the predominant institutions from Turkey accounting for a total of 80 published materials. Conclusion: The findings of this bibliometric analysis not only showed the contribution of Turkish authors to the field of pediatric anesthesia but also revealed the areas of improvement for their future research. The study also showed a list of journals that publish articles in the area of pediatric anesthesia.
Birsen Şentürk Pilan, Serpil Erermiş, Reyhan Çalışan, Begüm Yuluğ, Sibel Helin Tokmak, Sezen Köse, Burcu Özbaran, Tezan Bildik
Journal of Dr. Behcet Uz Children s Hospital, Volume 11, pp 167-173;

Objective: The aim of the presented study is to evaluate the adaptive process and psychiatric symptoms in the 7-12 age group followed-up with telemedicine interviews during the height of the pandemic. Method: Patients between the ages of 7-12 who were followed up in our outpatient clinic were called by telemedicine service at the appointment date. The questionnaire prepared by the researchers in order to investigate the adaptation process to the pandemic was administered, the answers provided by the patients and their families were recorded in the case data form together with Clinical Global Impression (CGI) Scale score appraised by the interviewing psychiatrist. Medical records pertaining to each patient were also reviewed, their psychiatric diagnoses, according to DSM 5 criteria and CGI scores recorded in their last face-to-face interviews during the pandemic period, were included in the case data form. Results: Fifty patients were included in the study. The mean age of the participants was 9.14±1.61 years. Attention deficit hyperactivity disorder (60%) was the most common psychiatric diagnosis detected in the participants before the pandemic, followed closely by anxiety and related disorders (20%) and specific learning difficulty (16%). The CGI scores of the cases before, and during the pandemic were 2.72±0.75, and 2.92±0.94, respectively. The difference between the mean scores was statistically significant (p=0.024). Conclusion: Our study emphasizes the importance of follow-up by telemental health practices in cases where face-to-face psychiatric interviews are not applicable, i.e., due to the risk of transmission of COVID-19 disease during the current pandemic
Havva Yazıcı, Ebru Canda, Esra Er, Barış Malbora, Burcu Öztürk Hismi, Hüseyin Onay, Serap Aksoylar, Sema Kalkan Uçar, Ferda Özkınay, Mahmut Çöker
Journal of Dr. Behcet Uz Children s Hospital, Volume 11, pp 198-201;

Mucopolysaccharidosis type I (MPS I) is a lysosomal storage disease due to mutations within the gene IDUA encoding the “α-L-iduronidase”. The clinical manifestations concern multisystemic involvement. There are two disease modifying therapies, enzyme replacement therapy and haematopoietic stem cell transplantation (HSCT). Pulmonary haemorrhage (PH) is a rare complication of HSCT and the case was presented with the reason that the related reports were few in MPS I.
Şennur Keleş, Serkan Filiz, Ali Erarslan, Gufat Arslan, Muhammed Furkan Bakkal
Journal of Dr. Behcet Uz Children s Hospital, Volume 11, pp 269-276;

Objective: The prevalence and the risk factors influencing allergic disorders in amateur athletes are still poorly defined. The aim of this study was to evaluate the prevalence and risk factors of the common allergic disorders in school aged athletes compared with the general population in southwest of Turkey. Methods: Using the “International Study of Asthma and Allergy in Childhood (ISAAC) Phase I” questionnaire, 714 athletes aged 7-18 and 325 age-matched healthy controls were examined. Risk factors that would affect the prevalence were evaluated with the questions given in addition to this questionnaire. Results: In the athlete group, the prevalence of existing asthma, allergic rhinitis, and eczema was lower than controls [(3.8%) and (16.3%), respectively, p<0.001], [(18.7%) and (42.1%)], respectively, p <0.001] and [(5.5%) and (10.5%), respectively, p<0.001]. Multivariate logistic regression analysis revealed that in the athlete population, a previously known allergy increased risk of curent wheezing (odds ratio [OR] =5.3; confidence interval, [CI]=1.8-15.4), current allergic rhinitis ([OR]=2.8; [CI]=1.3-6.2), and current eczema [OR]=4.5; [CI]=1.1-17.1). Familial atopy increased risk of current allergic rhinitis (OR=2.2; CI=0.9-4.9), and current eczema ([OR] = 6.6; [CI]=1.7-25.7). Conclusion: This study is the first prevalence study using the ISAAC method in school-age sports children in southwestern Turkey. Unlike adults, the prevalence of asthma, allergic rhinitis and eczema was found to be lower than controls of the same age. It is thought that sports and spending more time outdoors in children reduce allergic inflammation.
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