International Journal of Analytical Mass Spectrometry and Chromatography

Journal Information
ISSN / EISSN : 23321768 / 23321776
Current Publisher: Scientific Research Publishing, Inc, (10.4236)
Total articles ≅ 53
Archived in
SHERPA/ROMEO
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Latest articles in this journal

Belén Gastaca, Hernán Rubén Sánchez, Fiorella Menestrina, Maricel Caputo, María De Las Mercedes Schiavoni, Jorge Javier Pedro Furlong
International Journal of Analytical Mass Spectrometry and Chromatography, Volume 7, pp 19-34; doi:10.4236/ijamsc.2019.72003

Yutaka Okada, Masako Tsuchida
International Journal of Analytical Mass Spectrometry and Chromatography, Volume 7, pp 1-8; doi:10.4236/ijamsc.2019.71001

Abdlazim Mohamed Ali, Hana Jumma Ali Jumma
International Journal of Analytical Mass Spectrometry and Chromatography, Volume 7, pp 9-17; doi:10.4236/ijamsc.2019.71002

Ilia Brondz
International Journal of Analytical Mass Spectrometry and Chromatography, Volume 7, pp 35-36; doi:10.4236/ijamsc.2019.73004

Abstract:Chemistry is one of the eldest and basic sciences. The technological progress is depending on progress in chemistry. Without evaluation of nature and preparation of a pure substance, it is not imaginable existence of modern biology, medicine, metallurgy and physics. All kind of existing technologies needs distinct in nature and pure in quality substances for existence and further progress. RG aims to bring together leading academic scientists, researchers and research scholars to exchange and share their experiences and research results on all aspects of chemistry and related fields. It also provides an interdisciplinary platform for researchers, practitioners and educators to present and discuss the most recent innovations, trends, and concerns as well as practical challenges encountered, and solutions adopted in the fields of chemistry. One of the nearly developed concepts in liquid chromatography is described in [1], which is a new type of liquid chromatography, the new technology as the Colloidal High-Performance Liquid Chromatography (CHPLC). This type of new technological approach in high-performance liquid chromatography is a simple time- and labor-saving one-step procedure suitable for analytical-, semipreparative-, and preparative-scale preparation of bacteriocins and other cationic antibacterial peptides as well as other cationic small molecular weight species. It allows to suspensions of bacterial cells, other colloidal and fast-particle materials, and dissolved anionic molecules passed through the column; however, cationic bacteriocins, small cationic peptides, organic cationic molecules and metal cations were separated by chromatography. The purity of the target substance generally at more than 95% was achieved by the judgment of spectral, chromatographic, and antimicrobial activity. In [1] was described the preparation, purification and chromatography of bacteriocin, bacitracin and lysozyme. It is my pleasure to invite all the great scientists, academicians, young researchers, students and everyone who is interested in Science, especially in chemistry from all over the world to attend the RG. All who are interested in theoretical and applicational aspects in Chemistry, New Materials Research and Nanotechnology will find them in RG. The topics as: Organic Chemistry and Advances in Organic Chemistry, Analytical Chemistry, Medicinal Chemistry, Clinical Chemistry, Forensic Chemistry, Industrial Chemistry and Occupational Chemistry, Food Chemistry, Green Chemistry and Chemical Renewable Resources, Agricultural and Food Chemistry, Physical and Theoretical Chemistry, Biological Chemistry, Marine Chemistry, Inorganic Chemistry, Environmental Chemistry, Nanoscience and Technology, Polymer Chemistry, Material Chemistry, Natural Resources Chemistry and Natural Products Chemistry, Electrochemistry, Geochemistry, Radio and Nuclear chemistry, Physical Chemistry, Theoretical Chemistry, Space (Interplanetary) Chemistry and many more are...
Ilia Brondz
International Journal of Analytical Mass Spectrometry and Chromatography, Volume 6, pp 37-39; doi:10.4236/ijamsc.2018.62003

Abstract:This short communication is an overview and revision of previous published papers about the relative and absolute stereochemistry of hyperforin and discovery of a new isomer of hyperforin that has been named perforatrin.
Wei-Hsi Chen, Yu-Chieh Hsiao, Ming-Hsin Li, Mu-Chen Tsai, Chun-Fang Feng, Han-Chih Chang, Hung-Wen Yu, Chyng-Yann Shiue
International Journal of Analytical Mass Spectrometry and Chromatography, Volume 6, pp 1-19; doi:10.4236/ijamsc.2018.61001

Ilia Brondz
International Journal of Analytical Mass Spectrometry and Chromatography, Volume 6, pp 41-49; doi:10.4236/ijamsc.2018.63004

Abstract:A simple time- and labor-saving one-step procedure suitable for analytical-, semipreparative-, and preparative-scale preparation of bacteriocins and other cationic antibacterial peptides (for example as lysozyme) has been developed. Suspensions of bacterial cells, other colloidal- and fast-particle materials, and dissolved anionic molecules passed through the column; however, cationic bacteriocins were separated by chromatography. The purity of the target substance at more than 97% was achieved by the judgment of spectral, chromatographic, and antimicrobial activity. A many-fold concentration increase was achieved for bacteriocins, lysozyme, and bacitracin (a commercial antibiotic) in comparison with the starting solutions (see the text below). In the experiments, homemade cation-exchange columns have been used. The columns have been prepared by the grafting of glass fibers with a diameter of 0.2 μm. In this paper, applications of a new type of liquid chromatography―colloidal high-performance liquid chromatography (CHPLC)―were demonstrated.
Dev Kant Shandilya, Peter Edward Joseph, Anoop Kumar, Manoj Pillai
International Journal of Analytical Mass Spectrometry and Chromatography, Volume 5, pp 57-69; doi:10.4236/ijamsc.2017.53004

Abstract:The study focused on the application of high-resolution mass spectrometry for the identification of impurities in pharmaceutical small molecules. A high-performance liquid chromatography (HPLC) coupled high resolution mass spectrometer (HRMS) was used for identification of oxidative degradation impurities (DIs) of lansoprazole. The utilization of HRMS facilitates to determine the accurate mass of impurities and their fragment/product ions. A fast mass spectrometer (MS) compatible reverse phase chromatography method was used to investigate the oxidative stressed impurities. HPLC column; C18 (50 × 4.6 mm, 3.5 μm) was used with gradient elution. Spectral data acquired using information dependent acquisition (IDA) with real time dynamic background subtraction algorithm (DBS). Three oxidative impurities: DI-I (m/z 386.0781), DI-II (m/z 402.0734) and DI-III (m/z 386.0785), was observed during this study; interpretation of high resolution spectral data of all three impurities was carried out; elemental composition and molecular structure was proposed for major fragments. In this study mass error was found ≤7.7 parts per million (ppm).