Geriatric Care

Journal Information
ISSN / EISSN : 2465-1109 / 2465-1397
Published by: PAGEPress Publications (10.4081)
Total articles ≅ 142
Current Coverage
DOAJ
Archived in
SHERPA/ROMEO
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Latest articles in this journal

, Tasleem Akhtar, Muhammad Asif Faheem, Zari Salahuddin, Nasir Muhammad
Published: 18 March 2022
Geriatric Care, Volume 8; https://doi.org/10.4081/gc.2022.10150

Abstract:
Asthma is a chronic inflammatory disease of the lower airways, characterize by wheezing cough, chest tightness along with inflammation of airway and shortness of breath. Allergens like environmental substance are predispose asthmatics patients to allergy. Mast cells produced interleukin (IL)- 4 which either activate signal transducer and activator of transcription 6 (STAT-6) pathway that involved in differentiation of na ve T-cells to TH2 or activation of TH2 cells indirectly. The aim of the current context is to present role of IL-4 in asthma and effect as antagonist. IL-4 results in increased mucus production and involve in IgE synthesis from B cells. IL4 facilitate chemotaxis and aid in displaying of VCAM-1 which attract eosinophil basophils monocytes T-lymphocytes to blood vessel. IL4 inhibit apoptosis either by preventing decrease in BCL-2 level or binding of FasL to Fas (cd32) receptor which result in acute allergic response. Elevated level of IL-4 has greatly adverse impact on asthmatic patients so by decreasing the level of IL-4 will greatly reduce asthma phenotype.
Andrea Fabbo, , Elisabetta Genovese, Patrizia Mecocci, Alberto Cella, Carlo Custodero, Vittorio Ferrero, Francesco Saverio Ragusa, Alberto Pilotto
Published: 18 March 2022
Geriatric Care, Volume 8; https://doi.org/10.4081/gc.2022.10455

Abstract:
Hearing loss is a common condition in older people. Increasing research has shown that this condition is associated with a higher risk of several health problems. The aim of this survey made among the members of the Societa' Italiana Geriatria Ospedale e Territorio (SIGOT) is to explore how far hearing loss is known in the Italian geriatric community and how to develop a collaboration with other services. A short survey (taking approximately 5 min to complete) was freely available on the SIGOT website and disseminated using social channels. The questionnaire was available during the whole year of 2021. The questionnaire specifically addressed general characteristics/ demographics, general attention to hearing loss problem in older people and relationships with the National Health System, and personal opinions regarding hearing loss. A total of 122 participants (mainly females and aging between 61-70 years) from all Italian Regions were included. The SIGOT members answered that they consider hearing loss as clinically relevant is always important (55.7%). Unfortunately, many members had not audiological centers or specialists available. Moreover, 38.5% of SIGOT members reported that the possibility of correction of hearing loss with prostheses or cochlear implants in older people is very good for older patients and that in 87.7% a significant improvement in quality of life was observed. The interest in hearing loss problems in older people perceived by the SIGOT members is elevated, but some barriers, particularly in the availability of other specialists and in the services given by National Health System are still very limited.
Alberto Pilotto, Stefania Maggi, Alberto Ferrari, Giuseppe Rengo, Vincenzo Solfrizzi, Sabrina Zora, Ovidio Brignoli, Pierangelo Lora Aprile, Giuseppe Fascella, Ligia J. Dominguez, et al.
Published: 18 March 2022
Geriatric Care, Volume 8; https://doi.org/10.4081/gc.2022.10388

Abstract:
The multidimensional prognostic index (MPI) is a comprehensive geriatric assessment (CGA) tool exploring the multiple domains of older subject. The knowledge and the diffusion of self-assessment tools for identifying frailty in general medicine is still limited. The aim of our study is to determine the prevalence of frailty using a multidimensional frailty screening tool (SELFY-MPI) in a cohort of older adults, belonging to the general practitioner’s (GPs) experience. In the frame of a national educational program organized by the Italian Geriatric Hospital and Community Society (SIGOT), expert geriatricians carried-out local courses addressed to GPs, focused on multidimensional approach in primary care. A cross-sectional study of the SELFY-MPI, based on eight different domains, in the general practitioners’ outpatient clinic was performed among 50 GPs. SELFY-MPI risk score was used for dividing the participants in robust, pre-frail, or frail. A total of 526 participants (mean age: 77.7 years; females=55.3%) fulfilled the SELFY-MPI. The participants were, on average, independent in the activities of daily living, had a good mobility, but they reported some cognitive difficulties, and they can be considered at risk of malnutrition. A high prevalence of comorbidities and polypharmacotherapy was also present. The 20.2% of the sample lived alone, suggesting a potential social frailty. The mean SELFY-MPI score was 0.26 0.17: therefore, 21.67% of the participants were categorized as pre-frail, and 3.99% as frail. Pre-frailty and frailty are common in GPs experience. SELFY-MPI is a feasible screening tool for multidimensional frailty in the GPs clinical practice.
Johanna Marietta Christiansen, Anna Maria Meyer, Lena Pickert, Roman Pfister, Maria Cristina Polidori
Published: 18 March 2022
Geriatric Care, Volume 8; https://doi.org/10.4081/gc.2022.10384

Abstract:
Research on geriatric conditions and atypical disease presentation in poorly studied patients’ groups is becoming increasingly important. Aim of the present investigation was addressing prevalence and prognostic significance of aortic valve stenosis (AVS) in older residents of long-term care facilities (LTCF). For the planned recruitment of 500 LTCF guests of a German metropolitan area, study investigators were trained and in the performance of a cardiologic examination and of the comprehensive geriatric assessment- based multidimensional prognostic index (MPI). After five attempts to obtain permission to conduct the study in 30 institutions, patients’ recruitment was stopped with 22 participants included from one institution. AVS was suspected in two patients, in agreement with the reported prevalence data. The MPI value correlated with social support (P=0.002) and geriatric syndromes (P=0.004). This structured attempt at investigating presence and prognostic signature of AVS in older LTCF guests was challenged by logistic obstacles strongly hindering diagnosis of potentially treatable conditions which, if undisclosed, negatively impact on survival and quality of life.
, Dawn Chingtung Au, Albert Wingnang Leung, Chuanshan Xu
Published: 18 March 2022
Geriatric Care, Volume 8; https://doi.org/10.4081/gc.2022.10435

Abstract:
Elderly people have sleeping disorder problems which can be occurred frequently. This is a significant public health issue because sleeping disorder leads to cause depression, diabetes, cardiovascular, Alzheimer’s disease. Currently, music therapy might be a good choice instead of western medicines for the treatment of a sleeping disorder. This short communication describes the background of sleeping disorder, music therapy, and its research progress as well as the future development. A simple systematic search of publications in PubMed, Embase, Cochrane Library, and google search without language restriction is performed. Because of the little finding on the music therapy for sleep disorders in present literature, therefore, there is a short communication written by some literature reviews before starting a novel study of sleeping disorders for elderly people.
, Samuel Mwangi, George Owino
Published: 31 December 2021
Geriatric Care, Volume 7; https://doi.org/10.4081/gc.2021.10293

Abstract:
Research on the social well-being (SWB) of older persons in relation to social support provided and received has generated considerable amount of scholarly debate. Social support received or provided has been found in literature to produce mixed effects (positive and negative) on SWB, necessitating further research. The current study provides Kenyan evidence to a corpus of research mostly focused on European and American studies, contributing to the current discussion on SWB. Thus, the aim of the present study is to investigate how closeness to close network members (CNM) influences older persons’ satisfaction with social support provided and received. The study adopted a descriptive cross-sectional study design and mixed methods approach. Chi-square analyses were conducted, and the results revealed that there was a significant relationship between closeness and satisfaction with providing social support with exact P value of 0.002. In addition, there was a significant relationship between closeness and satisfaction with received social support with exact P value of 0.000 (P<0.05). The research highlights that closeness to CNM enhances SWB when older persons provide or receive social support.
Published: 31 December 2021
Geriatric Care, Volume 7; https://doi.org/10.4081/gc.2021.9891

Abstract:
Dementia is a syndrome of acquired intellectual deficit resulting in significant impairment of social or occupational functioning. Vascular dementia (VaD) is the second most common causes of dementia after Alzheimer’s disease, causing around 15% of cases. However, unlike Alzheimer’s disease an involvement of the cerebral cholinergic system in the pathophysiology of VaD has been hypothesized and there is no standard treatment. In the Vascular Dementia Italian Sulodexide Study (VA.D.I.S.S.) the positive results obtained with the sulodexide are worthy of note. In this study 40 elderly subjects with recent onset (less than 9 month) slight to moderate mental deterioration due to vascular origin were observed for nine months during oral treatment with sulodexide and choline alphoscerate with the aim of analyzing whether therapeutic effects can be enhanced. These preliminary results suggest that the additional therapy of choline alphoscerate with sulodexide represents a way to increase the beneficial effects of cholinergic therapies in the VaD and improve all the different examinate score: mini mental state evaluation (MMSE), basic activities of daily living (ADL), instrumental activities of daily living (IADL).
Anil Bhandari, Surya Pratap Singh Tiwari, Monika Rathore, , Smita Jain
Published: 31 December 2021
Geriatric Care, Volume 7; https://doi.org/10.4081/gc.2021.9908

Abstract:
India launched its coronavirus disease 2019 (COVID-19) vaccination drive starting with healthcare workers. The aim of the study was to evaluate adverse events following immunization (AEFI) amongst the Geriatric population associated with two doses of ChAdOx1 nCoV-19 vaccine. We also evaluated association of AEFI according to gender and elderly age groups. An observational study, conducted among 437 individuals vaccinated at multiple community healthcare centers in Jaipur, of AEFIs associated with both doses of ChAdOx1 nCoV-19 vaccine, via telephonic interviews on the day of vaccination-Day 0, Day 7 and Day 15 from vaccination. 463 vaccinated individuals who responded for first dose AEFIs, and 437 (94.3% 437/463) responded to the telephone interview regarding the second dose. Of these, 5.5% (24/437) reported AEFIs for the second dose. Among 60 respondents who reported AEFI (both doses) fever (26) and fatigue (22) were the most reported systemic AEFI. Local AEFIs were injection site soreness (23). The AEFIs (both systemic and local) in respondents mostly lasted for 1-2 days. AEFI reported by respondents in the age group 60- 70 years was higher than those above 70 years. Female respondents were associated with higher AEFI than the males. The AEFIs of both the doses were observed in the first 2 days predominantly. Symptoms were minor, short lived and selflimiting. No serious adverse events attributable to vaccines were reported in our study. Adverse event following immunization is independent of gender and age distribution for both the doses.
Luca Pellizzari, Camilla Ferronato, Andrea Variola, Martina Setti,
Published: 31 December 2021
Geriatric Care, Volume 7; https://doi.org/10.4081/gc.2021.10280

Abstract:
Syncope is a common reason for emergency room visits and hospital admission and, in about one patient out of six it can be a manifestation of pulmonary embolism (PE). The prognosis of this condition is largely dependent on the timing of diagnosis and treatment since early anticoagulation may modify the clinical consequences of PE and further loss of consciousness. In this article, we describe the case of a woman presenting with syncope, who showed at the admission a cardiac ultrasound highly specific cluster of signs of pulmonary embolism. This rapid non-invasive evaluation permitted to identify causal diagnosis and to speed up the clinical process.
Published: 21 September 2021
Geriatric Care, Volume 7; https://doi.org/10.4081/gc.2021.10036

Abstract:
Growing life expectancy is challenging the quality of health care for elderly. Information regarding health related quality of life (QOL) may help policy makers to design need based health programs for this population. The objectives of this study were to estimate health related QOL of the geriatric population living in rural areas of West Tripura district and to compare it between ethnic and non-ethnic populations in respect to important domains. This community based cross-sectional study was conducted during 1st February 2019 to 31st March 2020 among 225 geriatric subjects of rural West Tripura district chosen by multistage sampling. World Health Organization’s QOL-BREF scale was used for data collection. Among the study population 46.2% had overall good health related QOL. About 52.9% had good QOL in environment and 37.3% had good QOL in social relationship domains. Marginally higher proportion of the subjects from ethnic origin had better QOL than the non-ethnic but it was not significant. Higher proportion of the Muslim subjects had better QOL than the rest, but it was also not significant. Bivariate analysis showed significant associations of QOL with age, sex, literacy, financial condition, socioeconomic status and type of family. Multivariate analysis identified male sex, younger age and living with spouse as significant predictors of good QOL. Overall health related QOL of the geriatric people living in rural areas of West Tripura district is poor but younger male subjects, of ethnic origin and living with spouse may enjoy relatively better QOL.
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