International Journal of Ophthalmic Research

Journal Information
ISSN : 2409-5680
Current Publisher: ACT Publishing Group (10.17554)
Total articles ≅ 65
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Omer Karti, Ali Osman Saatci
International Journal of Ophthalmic Research, Volume 5, pp 302-307; doi:10.17554/j.issn.2409-5680.2019.05.86

Abstract:
Intravitreal Dexamethasone Implant (IDI) (Ozurdex®, Allergan, Inc. Irvine, CA) is the sustained-release corticosteroid device approved by the US Food and Drug Administration for the treatment of macular edema resulting from diabetes mellitus, non-infectious uveitis and retinal vein occlusion. Along with its anti-inflammatory effects, the most common associated side-effects are cataract formation and intraocular pressure (IOP) elevation. Although the exact pathophysiological mechanism remains unclear, increased aqueous outflow resistance resulted from the biochemical and structural changes in the trabecular meshwork is deemed responsible for the already well-known IOP elevation. This mini-review evaluated the major clinical trials on IOP changes following the 0.7 mg IDI administration and summarized their main results on IOP changes and its management.
Pragati Garg, Smriti Mishra, Ritika Mullick
International Journal of Ophthalmic Research, Volume 5, pp 308-313; doi:10.17554/j.issn.2409-5680.2019.05.87

Abstract:
AIM: The present study was carried out with an aim to study the concordance and correlation of microalbuminuria, dyslipidemia with the severity of Diabetic Retinopathy in type II diabetes mellitus patient and to provide a possible basis for explanation of mechanisms governing this relationship.MATERIAL AND METHOD: The study was conducted in a tertiary care hospital in North India.The patients underwent thorough history and ocular evaluation.The patients included in the study were advised to undergo biochemical investigations for Blood sugar, Urinary albumin to creatinine ratio in a random spot collection of urine and Lipid profile. Patients with acute or chronic renal failure, Opaque/hazy ocular media preventing fundus visualization, Co-existing ocular disorders likely to mask the findings of diabetic retinopathy, Patients with presence of any of the confounding factors, like fever, active systemic infections, exercise, high protein intake, accelerated hypertension, congestive heart failure, patients not willing to participate in the study were excluded from the study.RESULTS: 444 subjects of either gender were included in our study, out of which 236 patients were females and the rest were males. Majority of the patients lied in the age group of 41-60 years (54.73%) followed by 61-80 years (29.28%) and 20-40 years (15.09%), while only 4(0.90%) patients were aged >80 years. A statistically significant association with severity of retinopathy and the age of the patients was observed. Proportion of Group I (No retinopathy) was higher in younger patients i.e. 20- 40 (74.6%) and 41-60 (54.3%) as compared to elderly cases i.e. 61-80 (46.2%) and this difference was found to be statistically significant (p
Cagri Ilhan
International Journal of Ophthalmic Research, Volume 5, pp 299-301; doi:10.17554/j.issn.2409-5680.2019.05.77

The publisher has not yet granted permission to display this abstract.
Almamoun Abdelkader
International Journal of Ophthalmic Research, Volume 5, pp 317-320; doi:10.17554/j.issn.2409-5680.2019.05.89

Abstract:
Purpose: To evaluate and compare in a masked fashion the influence of using two different concentrations of carbachol drops on the outcome of presbyopia treatment. Methods: A prospective, double-masked, randomized study. 57 emmetropic and presbyopic subjects aged between 44 and 60 years with an uncorrected distance visual acuity of at least 20/20 in both eyes without additional ocular pathology were eligible for inclusion. Subjects were divided into 2 groups. Group 1 (n=32 eyes) received single dose of 2.25% carbachol plus 0.2% brimonidine eye drops. Group 2 (n=25) received single dose of 3% carbachol plus 0.2% brimonidine eye drops. The subjects’ pupil size and both near and distance visual acuities were evaluated before and after treatment at 1, 2, 4, 8 and 12 hr, by a masked examiner at the same room illumination. Results: Statistically significant improvement in mean near visual acuity (NVA) was achieved in all subjects who received both concentrations of carbachol plus brimonidine drops (P < 0.0001). Significant and sustained improvement in mean NVA was reported in higher concentrations of carbachol drops than in lower concentrations (P < 0.0001). No serious adverse ocular effects were observed in any of the subjects of both groups. Conclusion: Based on the data, higher concentration of carbachol was found to be safe and provided greater efficacy in improving near visual acuity than lower concentration with prolonged duration of action.
Patrick W. Commiskey, Curtis J. Heisel, Yannis M. Paulus
International Journal of Ophthalmic Research, Volume 5, pp 321-335; doi:10.17554/j.issn.2409-5680.2019.05.90

Abstract:
Background: As lasers have become an increasingly important component of commercial, industrial, military, and medical applications, reported incidents of non-therapeutic laser eye injuries have increased. The retina is particularly vulnerable due to the focusing power and optical transparency of the eye. Continued innovations in laser technology will likely mean that lasers will play an increasingly important and ubiquitous role throughout the world. Critical evaluation should thus be paid to ensure that non-therapeutic injuries are minimized, recognized, and treated appropriately.Methods: A comprehensive literature review on the PubMed database was conducted to present case reports and case series representative of the variety of laser eye injuries in different injury circumstances, tissue types, and biological damage mechanisms.Results: A general summary of non-therapeutic laser retina injuries is presented, including information about growth of the industry, increasingly accessible online markets, inconsistent international regulation, laser classifications, laser wavelengths, and laser power, mechanisms of tissue injury, and a demonstration of the variety of settings in which injury may occur. Finally, 68 cases found in the literature are summarized to illustrate the presentations and outcomes of these patients.Conclusions: As non-therapeutic laser eye injuries increase in frequency, there is a greater need for public health, policy, diagnosis, and treatment of these types of injuries.
Almamoun Abdelkader
International Journal of Ophthalmic Research, Volume 5, pp 314-316; doi:10.17554/j.issn.2409-5680.2019.05.88

Abstract:
Objective: To evaluate and compare the efficacy of using conjunctival autograft and non-bare sclera mitomycin C (MMC) techniques as two treatment options for primary pterygium. Patients and Methods: Retrospective comparative study included 55 eyes in 55 patients with primary pterygium. 30 eyes of 30 patients (group 1) underwent pterygium excision followed by conjunctival autograft. 25 eyes of 25 patients (group 2) underwent pterygium removal followed by intraoperative application of 0.02% MMC for 2 minutes with conjunctival preservation (non-bare sclera technique). Both groups were compared in terms of surgery time, pterygium size, cosmetic effect, pterygium recurrence and complications. Results: Mean pterygium size was (3.1 ± 0.64 mm and 2.6 ± 0.94 mm) in group 1 and 2, respectively (p =0.1). Mean surgery time was significantly shorter in MMC group (26.4 ± 6.39 min) as compared to conjunctival autograft group (47.9 ± 11.7 min) (P < 0.0001). Pterygium recurrence was not seen in any of the patients. Mean follow up time was (14.8 ± 6 and 17.2 ± 9.6 months) in group 1 and 2, respectively (p = 0.4). Conclusion: Both conjunctival graft and non-bare sclera MMC techniques are comparable as regard of pterygium recurrence. MMC technique has significantly shorter surgery time, better cosmoses and lower incidence of complications. Preserving the conjunctiva should be considered when the patient has a history of glaucoma or there is insufficient conjunctiva.
Carolina Arruabarrena, Daniele Ferrari
International Journal of Ophthalmic Research, Volume 4, pp 287-290; doi:10.17554/j.issn.2409-5680.2018.04.83

The publisher has not yet granted permission to display this abstract.
Burak Simsek, Hakan Yildirim, Hamdi Tasli
International Journal of Ophthalmic Research, Volume 4, pp 265-267; doi:10.17554/j.issn.2409-5680.2018.04.73

The publisher has not yet granted permission to display this abstract.
Pragati Garg , Smriti Misra, Swati Yadav, Luxmi Singh
International Journal of Ophthalmic Research, Volume 4, pp 282-286; doi:10.17554/j.issn.2409-5680.2018.04.79

The publisher has not yet granted permission to display this abstract.
Raffaella Morreale Bubella, Cillino S
International Journal of Ophthalmic Research, Volume 4, pp 268-271; doi:10.17554/j.issn.2409-5680.2018.04.76

Abstract:
AIM: To evaluate the lipid profile and the evolution of the damage of the visual field in 2 groups of patients with POAG, one group of patients with type A Behaviour and the other with type B Behaviour.METHODS: The study involved 45 patients, 26 women and 19 men, affected by POAG, without significant differences in disease duration. 25 patients presented characteristics of type A behaviour and 20 characteristics of type B behaviour. They are submitted to an complete bio-microscopic examination, tonometry and daily tonometric curve, examination of the visual field through computerized “Octopus 1-2-3” perimeter and determination of the lipid profile (total cholesterol, HDL Cholesterol; LDL Cholesterol, Triglycerides) at time 0 and after 3 years.RESULTS: In patients with type A behaviour the values relating to the single components of the lipid profile both at time 0 and after 3 years proved to be constantly higher in a statistically significant way than those found in patients with type B behaviour and the impairment of the visual field is more serious and that its evolution in time is more marked.CONCLUSION: The more rapid progression of the damage of the visual field in patients with type A behavior could recognize in the altered profile lipid one of pathogenetic causes.
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