The Lancet

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ISSN / EISSN : 01406736 / 1474547X
Current Publisher: Elsevier BV (10.1016)
Total articles ≅ 462,750
Google Scholar h5-index: 278
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Sharmila Devi
Published: 12 October 2019
The Lancet, Volume 394, pp 1311-1312; doi:10.1016/s0140-6736(19)32306-2

Selina Lo
Published: 12 October 2019
The Lancet, Volume 394, pp 1313-1314; doi:10.1016/s0140-6736(19)32269-x

Richard M Bergenstal, Mary L Johnson, Eran Bashan, Israel Hodish
Published: 12 October 2019
The Lancet, Volume 394; doi:10.1016/s0140-6736(19)31895-1

The publisher has not yet granted permission to display this abstract.
David Miller
Published: 12 October 2019
The Lancet, Volume 394; doi:10.1016/s0140-6736(19)31248-6

Abstract:The clinical outcomes of the HABSelect trial1Miller D Pavitt S Sharma V et al.Physiological, hyaluronan-selected intracytoplasmic sperm injection for infertility treatment (HABSelect): a parallel, two-group, randomised trial.Lancet. 2019; 393: 416-422Summary Full Text Full Text PDF PubMed Scopus (1) Google Scholar indicated that physiological intracytoplasmic sperm injection (ICSI), a form of hyaluronan sperm-selection, could not be recommended for general use. Lodovico Parmegiani, not unreasonably, asks that in view of several reports2Worrilow KC Eid S Woodhouse D et al.Use of hyaluronan in the selection of sperm for intracytoplasmic sperm injection (ICSI): significant improvement in clinical outcomes--multicenter, double-blinded and randomized controlled trial.Hum Reprod. 2012; 28: 306-314Crossref Scopus (57) Google Scholar, 3Majumdar G Majumdar A A prospective randomized study to evaluate the effect of hyaluronic acid sperm selection on the intracytoplasmic sperm injection outcome of patients with unexplained infertility having normal semen parameters.J Assist Reprod Genet. 2013; 30: 1471-1475Crossref PubMed Scopus (12) Google Scholar, 4Mokanszki A Tothne EV Bodnar B et al.Is sperm hyaluronic acid binding ability predictive for clinical success of intracytoplasmic sperm injection: PICSI vs. ICSI?.Syst Biol Reprod Med. 2014; 60: 348-354Crossref PubMed Scopus (12) Google Scholar of a significant decrease in miscarriage in cohorts in which hyaluronan-selected sperm were used, why should it only be considered as an add-on to treatment? The answer lies in the primary question the HABSelect trial1Miller D Pavitt S Sharma V et al.Physiological, hyaluronan-selected intracytoplasmic sperm injection for infertility treatment (HABSelect): a parallel, two-group, randomised trial.Lancet. 2019; 393: 416-422Summary Full Text Full Text PDF PubMed Scopus (1) Google Scholar was designed to answer, which was: can physiological ICSI improve livebirth rates compared with standard ICSI? All other outcomes were a secondary consideration. Our trial was powered on that basis, and we reported a small (2·2%) but not significant increase in livebirths in the physiological ICSI cohort. Admittedly, this improvement was most likely driven by the corresponding reduction in miscarriage, and our data provide further evidence that physiological ICSI reduces miscarriages. However, as indicated in the accompanying Comment,5Repping S Evidence-based medicine and infertility treatment.Lancet. 2019; 393: 380-382Summary Full Text Full Text PDF PubMed Scopus (0) Google Scholar when making decisions regarding a potentially important change to clinical practice, we need to be very mindful of the quality of evidence overall. Therefore, we have been cautious in our interpretation of the results of a secondary analysis.
Suzanne Koven
Published: 12 October 2019
The Lancet, Volume 394, pp 1316-1317; doi:10.1016/s0140-6736(19)32272-x

Patience A Afulani, Cheryl A Moyer
Published: 8 October 2019
The Lancet; doi:10.1016/s0140-6736(19)32258-5

Abstract:Worldwide, maternal health efforts are shifting from an emphasis on boosting service utilisation to improving quality of care. This change has been accompanied by a growing body of work on how women are treated during facility-based childbirth, which was first brought to global attention in 2010 by Bowser and Hill's landscape analysis.1Bowser D Hill K Exploring evidence for disrespect and abuse in facility-based childbirth: report of a landscape analysis. USAID-Traction Project.https://cdn2.sph.harvard.edu/wp-content/uploads/sites/32/2014/05/Exploring-Evidence-RMC_Bowser_rep_2010.pdfDate: 2010Date accessed: September 15, 2019Google Scholar Several studies have documented the ubiquitous nature of disrespectful care and its adverse effects on care-seeking behaviour,2Bohren MA Vogel JP Hunter EC et al.The mistreatment of women during childbirth in health facilities globally: a mixed-methods systematic review.PLoS Med. 2015; 12e1001847Crossref PubMed Scopus (272) Google Scholar and calls to action on quality of maternal health care have prioritised women's experiences.3Miller S Abalos E Chamillard M et al.Beyond too little, too late and too much, too soon: a pathway towards evidence-based, respectful maternity care worldwide.Lancet. 2016; 388: 2176-2192Summary Full Text Full Text PDF PubMed Scopus (169) Google Scholar
Andrew Green
Published: 5 October 2019
The Lancet, Volume 394; doi:10.1016/s0140-6736(19)32228-7

The publisher has not yet granted permission to display this abstract.
Aarathi Prasad
Published: 5 October 2019
The Lancet, Volume 394, pp 1219-1220; doi:10.1016/s0140-6736(19)32225-1

Stéphanie Tchiombiano, Jean-François Delfraissy, François Dabis
Published: 5 October 2019
The Lancet, Volume 394, pp 1214-1215; doi:10.1016/s0140-6736(19)32261-5

Qi Zhou, Nan Yang, Kehu Yang, Janne Estill, Yaolong Chen
Published: 5 October 2019
The Lancet, Volume 394; doi:10.1016/s0140-6736(19)31409-6

The publisher has not yet granted permission to display this abstract.