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Results in Journal Circulation Journal: 8,432

(searched for: journal_id:(47217))
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Ayako Sekine, Takatomo Watanabe, Genki Naruse, Ayae Takada, Shingo Fujimoto, Noriko Ozawa, Koichi Shinoda, Yuzuru Nohisa, Hiroyuki Okura
Published: 19 November 2020
Circulation Journal; doi:10.1253/circj.cj-20-0779

Mai Iwataki, Yong-Jin Kim, Seung Woo Park, Lieng Hsi Ling, Cheuk-Man Yu, Hiroyuki Okura, Jong-Won Ha, Takeshi Hozumi, Hidekazu Tanaka, Chisato Izumi, et al.
Published: 19 November 2020
Circulation Journal; doi:10.1253/circj.cj-20-0412

Abstract:
Background:The aortic valve area index (AVAI) in aortic stenosis (AS) is measured by echocardiography with a continuity equation using the stroke volume index by Doppler (SVIDoppler) or biplane Simpson (SVIBiplane) method. AVAIDopplerand AVAIBiplaneoften show discrepancy due to differences between SVIDopplerand SVIBiplane. The degree of discrepancy and utility of combined AVAIs have not been investigated in a large population of AS patients, and the characteristics of subjects with larger discrepancies are unknown. Methods and Results:We studied 820 patients with significant AS (AVADoppler
Huihui Liu, Sifan Qian, Chongke Zhong, Aili Wang, Yanbo Peng, Hao Peng, Tan Xu, Xiaoqing Bu, Deqin Geng, Yonghong Zhang
Published: 19 November 2020
Circulation Journal; doi:10.1253/circj.cj-20-0771

Abstract:
Background:This study explored the value of cystatin C (CysC) in predicting stroke recurrence in patients with acute ischemic stroke. Methods and Results:This was a post hoc analysis of the China Antihypertensive Trial in Acute Ischemic Stroke (CATIS) on 3,474 acute ischemic stroke patients with documented serum CysC and high-sensitivity C-reactive protein (hsCRP) concentrations. Study outcomes included stroke recurrence and combined vascular events within 2 years after stroke. In stroke patients with higher (i.e., ≥4.8ng/mL), but not lower, hsCRP concentrations, a higher CysC concentration (i.e., ≥0.78 mg/L) was associated with a 2.48-fold increase in the risk of recurrent stroke (95% confidence interval [CI] 1.37–4.51; P=0.003) and a 2.04-fold increase in the risk of vascular events (95% CI 1.27–3.28; P=0.003). Serum hsCRP concentrations significantly modified the association of serum CysC with recurrent stroke (Pinteraction=0.001) and vascular events (Pinteraction=0.007). Moreover, CysC may improve reclassification of stroke recurrence (net reclassification improvement [NRI] 42.9%, P=0.001; integrated discrimination improvement [IDI] 1.2%, P=0.001) and vascular events (NRI 35.8%, P=0.001; IDI 1.1%, P=0.004). Conclusions:In ischemic stroke patients with high hsCRP concentrations, higher CysC concentrations increased the risk of stroke recurrence and vascular events. This indicates that the predictive value of CysC on stroke recurrence may depend on the inflammation status of patients.
Xiaoyang Song, Naritatsu Saito, Takeshi Morimoto, Tomohiko Taniguchi, Hiroki Shiomi, Kenji Ando, Kazuya Nagao, Norio Kanamori, Koichiro Murata, Takeshi Kitai, et al.
Published: 18 November 2020
Circulation Journal; doi:10.1253/circj.cj-20-0681

Abstract:
Background:Although diabetes mellitus (DM) is a common comorbidity of aortic stenosis (AS), clinical evidence about the long-term effect of DM on patients with AS is insufficient. Methods and Results:Data were acquired from CURRENT AS, a large Japanese multicenter registry that enrolled 3,815 patients with severe AS. Patients without initial valve replacement were defined as the conservative group; among them, 621 (23.4%) had DM, whereas 1997 did not. The DM group was further divided into 2 groups according to insulin treatment (insulin-treated DM, n=130; non-insulin treated DM, n=491). The primary outcome was a composite of aortic valve (AV)-related death and heart failure (HF) hospitalization. Secondary outcomes were AV-related death, HF hospitalization, all-cause death, cardiovascular death, sudden death, and surgical or transcatheter AV replacement during follow up. As a result, DM was associated with higher risk for the primary outcome (52.8% vs. 42.9%, P
Hiroto Kokubun, Yasushi Miyauchi, Shin Inada, Wataru Shimizu
Published: 17 November 2020
Circulation Journal; doi:10.1253/circj.cj-20-0979

Miki Tsujiuchi, Mio Ebato, Hideyuki Maezawa, Naoko Ikeda, Takuya Mizukami, Sakura Nagumo, Yoshitaka Iso, Takenori Yamauchi, Hiroshi Suzuki
Published: 14 November 2020
Circulation Journal; doi:10.1253/circj.cj-20-0617

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Shigeru Saito, Kentaro Hayashida, Morimasa Takayama, Tsuyoshi Goto, Leo Ihlberg, Yoshiki Sawa
Published: 14 November 2020
Circulation Journal; doi:10.1253/circj.cj-20-0064

The publisher has not yet granted permission to display this abstract.
Jiaqi Li, Hironori Imano, Kazumasa Yamagishi, Renzhe Cui, Isao Muraki, Mitsumasa Umesawa, Mina Hayama-Terada, Tetsuya Ohira, Masahiko Kiyama, Takeo Okada, et al.
Published: 13 November 2020
Circulation Journal; doi:10.1253/circj.cj-20-0384

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Naruya Ishizue, Shinichi Niwano, Hidehira Fukaya, Jun Oikawa, Jun Kishihara, Junya Ako
Published: 13 November 2020
Circulation Journal; doi:10.1253/circj.cj-20-0142

The publisher has not yet granted permission to display this abstract.
Ken Kozuma, Yoshihisa Kinoshita, Hirofumi Hioki, Mamoru Nanasato, Yoshiaki Ito, Junichi Yamaguchi, Nobuo Shiode, Kiyoshi Hibi, Kengo Tanabe, Junya Ako, et al.
Published: 13 November 2020
Circulation Journal; doi:10.1253/circj.cj-20-0644

The publisher has not yet granted permission to display this abstract.
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