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Results in Journal Italian Journal of Pediatrics: 1,827

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, Lida Bulbul, Umut Zubarioglu, Evrim Kıray Bas, Duygu Acar, Sinan Uslu,
Published: 17 October 2017
Italian Journal of Pediatrics, Volume 43; https://doi.org/10.1186/s13052-017-0415-3

The publisher has not yet granted permission to display this abstract.
Hokyoung Ryu, Garam Han, Jaeran Choi, Hyun-Kyung Park, Mi Jung Kim, Dong-Hyun Ahn, Hyun Ju Lee
Published: 2 October 2017
Italian Journal of Pediatrics, Volume 43; https://doi.org/10.1186/s13052-017-0408-2

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Published: 16 September 2017
Italian Journal of Pediatrics, Volume 43, pp 80-80; https://doi.org/10.1186/s13052-017-0401-9

Abstract:
This review reports main progresses in various pediatric issues published in Italian Journal of Pediatrics and in international journals in 2016. New insights in clinical features or complications of several disorders may be useful for our better understanding. They comprise severe asthma, changing features of lupus erythematosus from birth to adolescence, celiac disease, functional gastrointestinal disorders, Moebius syndrome, recurrent pneumonia. Risk factors for congenital heart defects, Kawasaki disease have been widely investigated. New diagnostic tools are available for ascertaining brucellosis, celiac disease and viral infections. The usefulness of aCGH as first-tier test is confirmed in patients with neurodevelopmental disorders. Novel information have been provided on the safety of milk for infants. Recent advances in the treatment of common disorders, including neonatal respiratory distress syndrome, hypo-glycemia in newborns, atopic dermatitis, constipation, cyclic vomiting syndrome, nephrotic syndrome, diabetes mellitus, regurgitation, short stature, secretions in children with cerebral palsy have been reported. Antipyretics treatment has been updated by national guidelines and studies have excluded side effects (e.g. asthma risk during acetaminophen therapy). Vaccinations are a painful event and several options are reported to prevent this pain. Adverse effects due to metabolic abnormalities are reported for second generation antipsychotic drugs.
, Federico De Luca, Alphonse K. Simbi, Matteo Parotto, Pietro Guerrini, Gianluca Straface
Published: 4 August 2017
Italian Journal of Pediatrics, Volume 43, pp 1-5; https://doi.org/10.1186/s13052-017-0382-8

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, Valentina Bortolotti, Michela Capogna, Margherita Guarnieri, Francesca Lucca, Rossella Gaudino, Stefano Marzini, Claudia Banzato,
Italian Journal of Pediatrics, Volume 43; https://doi.org/10.1186/s13052-017-0381-9

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Italian Journal of Pediatrics, Volume 43; https://doi.org/10.1186/s13052-017-0377-5

Abstract:
The aim of our study is to evaluate if in children with highly positive serology and HLA-DQ2/DQ8 (triple test, TT) and only extra-intestinal symptoms, it is possible to omit performing an intestinal biopsy for celiac disease (CD) diagnosis, as suggested by the new European Society for Pediatric Gastroenterology, Hepatology and Nutrition ESPGHAN guidelines. In this retrospective study a total of 105 patients, suspected of having CD because of extra-intestinal symptoms and showing serum tissue transglutaminase antibody (anti-tTG) and anti-endomysial antibody (EMA) measurements and HLA genotyping, were considered for the final analysis (33 boys and 72 girls; age range 1.5–17.6 years). Histological findings confirmed diagnosis of CD in 97 (92.4%) patients. Forty-one patients (39%) showed anti-tTG >10 times normal values, positive EMA and positive HLA-DQ2/DQ8 (positive TT). All of them had a diagnosis of CD, therefore there were no false positive cases. Sixty-four patients were negative for the TT. In eight cases, CD was ruled out and these were considered true negative cases. In the remaining 56 negative TT patients, intestinal biopsy confirmed CD diagnosis and they were considered false negatives. Based on these results, specificity for the TT was 100% and sensitivity was 42.3%. On the basis of the present study, diagnosis of CD can be reliably performed without a duodenal biopsy in children with only extra-intestinal symptoms.
, Gaia Pecorelli, Marina Bianchi, Massimo Cartabia, Gianluigi Casadei, Ada Pluda, Cristina Quecchia, Valeria Gretter,
Italian Journal of Pediatrics, Volume 43; https://doi.org/10.1186/s13052-017-0374-8

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