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Journal Clinica Chimica Acta

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36,537 articles
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Yuling Bin, Yong Ding, Weisheng Xiao, Sciprofile linkAijun Liao
Published: 23 January 2020
Clinica Chimica Acta; doi:10.1016/j.cca.2020.01.014

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Sciprofile linkSeiji Kobayashi, Hoichi Amano, Hiroyuki Terawaki, Yoshindo Kawaguchi, Takashi Yokoo
Published: 1 January 2020
Clinica Chimica Acta, Volume 500, pp 1-9; doi:10.1016/j.cca.2019.09.012

Abstract:Presepsin is a useful biomarker to diagnose sepsis. However, the correlation between plasma presepsin concentrations and kidney function in the elderly with chronic kidney disease (CKD) remains to be elucidated. We determined whether plasma presepsin concentrations were influenced by kidney function decline in the elderly. One hundred seventy outpatients with CKD aged ≥65 y were enrolled. Plasma presepsin concentrations were measured using immunoassay analysis. The relationship between plasma presepsin concentration and kidney function was assessed. The median age of patients of this cohort was 778 (72–85) y and the mean estimated glomerular filtration rate was 51.8 ± 28.1 ml/min/1.73 m2. Plasma presepsin concentrations in those with CKD G4-G5 (362 pg/ml [273–553]) were significantly higher than in those with CKD G1-G2 (111 pg/ml [91–113]) and CKD G3 (145 pg/ml [124–205]) (p < 0.001, p < 0.001, respectively). A high correlation between plasma presepsin concentrations and kidney function was observed (R2 = 0.733, p < 0.001). Even after adjusting for confounders, plasma presepsin concentrations were independently associated with kidney function. Increases in plasma presepsin concentrations were exponentially correlated to kidney function decline in the elderly with CKD.
Fiammetta Piersigilli, Sciprofile linkVineet Bhandari
Published: 1 January 2020
Clinica Chimica Acta, Volume 500, pp 109-114; doi:10.1016/j.cca.2019.09.025

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Carmen Peña-Bautista, Lidia Flor, Marina López-Nogueroles, Lorena García, Inés Ferrer, Miguel Baquero, Máximo Vento, Sciprofile linkConsuelo Cháfer-Pericás
Published: 1 January 2020
Clinica Chimica Acta, Volume 500, pp 233-240; doi:10.1016/j.cca.2019.10.023

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Stefania Moz, Mariagrazia Lorenzin, Roberta Ramonda, Vittorio Aneloni, Massimo La Raja, Sciprofile linkMario Plebani, Sciprofile linkDaniela Basso
Published: 1 January 2020
Clinica Chimica Acta, Volume 500, pp 180-188; doi:10.1016/j.cca.2019.10.013

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Kerstin Wimmer, Monika Sachet, Sciprofile linkRudolf Oehler
Published: 1 January 2020
Clinica Chimica Acta, Volume 500, pp 87-97; doi:10.1016/j.cca.2019.10.003

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María José Ariza, Carmen Pérez-López, Fátima Almagro, Ana María Sánchez-Tévar, Ovidio Muñiz-Grijalvo, Luis Antonio Álvarez-Sala Walter, José Rioja, Miguel Ángel Sánchez-Chaparro, Sciprofile linkPedro Valdivielso
Published: 1 January 2020
Clinica Chimica Acta, Volume 500, pp 163-171; doi:10.1016/j.cca.2019.10.011

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Na Li, Yuming Qiu, Yunpeng Wu, Mo Zhang, Zhizhen Lai, Qing Wang, Yuying Du, Lei Guo, Shuai Liu, Sciprofile linkZhili Li
Published: 1 January 2020
Clinica Chimica Acta, Volume 500, pp 59-68; doi:10.1016/j.cca.2019.09.018

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Yuhuan Shen, Li Zhao, Sciprofile linkShiming Lu
Published: 1 January 2020
Clinica Chimica Acta, Volume 500, pp 42-46; doi:10.1016/j.cca.2019.10.002

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