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(searched for: doi:10.5155/eurjchem.4.3.207-210.780)
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, V. Madhusudhan Rao
Published: 1 August 2020
Chemical Data Collections, Volume 28; doi:10.1016/j.cdc.2020.100423

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Bathélémy Ngameni, , Victor Kuete, Erdin Dalkılıç, Bonaventure T Ngadjui, Arif Daştan
Journal of Chemical Research, Volume 45, pp 159-165; doi:10.1177/1747519820932789

Abstract:
A series of novel 4- O-alkyltriazolylphenolic derivatives is first synthesized with good to excellent yields via the click reaction of 3-methoxy-4- O-propargylbenzaldehyde or 3-allyl-4- O-propargylacetophenone and aromatic azide derivatives. Next, the chalcones are prepared via the Claisen-Schmidt method from 4- O-alkylphenylketone derivatives in the presence of the corresponding (hetero)aromatic aldehydes as electrophiles. The structures of the newly synthesized compounds are confirmed from their infrared, nuclear magnetic resonance spectral data, and by elemental analysis. The main advantages of this procedure are the simplicity of the reaction conditions, easily available starting materials, and simple work-up. The antioxidant activity of several of the products is determined using the DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate) radical scavenging assay. 4- O-propargylvanillin (IC50 = 14.54 µg/mL) had moderate antioxidant activity.
, Lav Kumar, Anjali Jha, Gattu Sridhar
Published: 1 August 2019
Chemical Data Collections, Volume 22; doi:10.1016/j.cdc.2019.100236

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, Vangala Santhosh Reddy, Karnewar Santosh, G. Bharath Kumar, Anver Basha Shaik, Rasala Mahesh, Sumit. S. Chourasiya, Ibrahim Bin Sayeed, Srigiridhar Kotamraju
Published: 1 January 2014
MedChemComm, Volume 5, pp 1718-1723; doi:10.1039/c4md00228h

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