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Published: 16 October 2021
by MDPI
Biomolecules, Volume 11; https://doi.org/10.3390/biom11101527

Abstract:
Genome technologies have revolutionized biomedicine, but the complexity of biological systems cannot be explained by genomics alone
Published: 16 October 2021
by MDPI
Abstract:
In the current study, a variety of sulfonated polyethersulfone (SPES)-based ion-exchange membranes were prepared and utilized as efficient and selective solid adsorbents for the detection of Co(II) ions in aquatic solutions. SPES membranes were treated with a variety of cations at a 2:1 ratio overnight. The produced materials were assessed via XRD, FT-IR, SEM, and TGA analyses. The structure of these materials was confirmed by FT-IR and XRD, which also confirmed the inclusion of Na+, NH4+, and amberlite on the SPES surface successfully. TGA analysis showed that the thermal stabilities of these materials were enhanced, and the order of stability was NH4-SPES > SPES > Na-SPES > A-SPES. Furthermore, the efficiency of these modified membranes for the determination and adsorption of a variety of metal ions was also examined by the ICP-OES analytical technique. A-SPES expressed a powerful efficiency of adsorption, and it showed an efficient as well as quantitative adsorption at pH = 6. Moreover, A-SPES displayed the highest adsorption capacity of 90.13 mg/g for Co(II) through the Langmuir adsorption isotherm.
Published: 16 October 2021
by MDPI
Energies, Volume 14; https://doi.org/10.3390/en14206735

Abstract:
The article presents a proposal to reduce energy consumption in a hydraulic system with a single pump and multiple receivers. The proposed Load-Sensing Basic (LSB) solution consists of expanding a typical hydraulic system by using additional logic valves and a dedicated differential valve. The modification is aimed at decrease in operating pressure and, thus, reduction in energy consumption. The LSB system is compact as all components are built on a single ISO plate. A detailed mathematical model of the system was formulated, then a simulation model was built and numerical tests were carried out in the Matlab/Simulink environment. The obtained results indicate that the use of the proposed LSB system for the implementation of typical working cycles with three actuators may reduce energy consumption by 4–30%, and under certain conditions even up to 70%.
Published: 16 October 2021
by MDPI
Nanomaterials, Volume 11; https://doi.org/10.3390/nano11102737

Abstract:
MXenes are a new class of two-dimensional (2D) materials with promising applications in many fields because of their layered structure and unique performance. In particular, the physical barrier properties of two-dimensional nanosheets make them suitable as barriers against hydrogen. Herein, MXene coatings were prepared on pipe steel by a simple spin-coating process with a colloidal suspension. The hydrogen resistance was evaluated by electrochemical hydrogen permeation tests and slow strain rate tests, and the corrosion resistance was assessed by potentiodynamic polarization. The results reveal that MXene coatings offer excellent hydrogen resistance and corrosion protection by forming a barrier against diffusion. Experimentally, the hydrogen permeability of the MXene coating is one third of the substrate, and the diffusion coefficient decreases as well. The mechanistic study indicates that the hydrogen resistance of the MXene coatings is affected by the number of spin-coated layers, while the concentration of the d-MXene colloidal suspension determines the thickness of a single coating. However, damage to the sample surface caused by the colloidal suspension that contains H+ and F may limit the improvement of the hydrogen resistance. This paper reveals a new application of 2D MXene materials as a novel efficient barrier against hydrogen permeation and the subsequent alleviation of hydrogen embrittlement in the steel substrate.
Published: 16 October 2021
by MDPI
Abstract:
The individualization of information processes based on artificial intelligence (AI), especially in the context of industrial tasks, requires new, hybrid approaches to process modeling that take into account the novel methods and technologies both in the field of semantic representation of knowledge and machine learning. The combination of both AI techniques imposes several requirements and restrictions on the types of data and object properties and the structure of ontologies for data and knowledge representation about processes. The conceptual reference model for effective individualization of information processes (IIP CRM) proposed in this work considers these requirements and restrictions. This model is based on such well-known standard upper ontologies as BFO, GFO and MASON. Evaluation of the proposed model is done on a practical use case in the field of precise agriculture where IoT-enabled processes are widely used. It is shown that IIP CRM allows the construction of a knowledge graph about processes that are surrounded by unstructured data in soft and heterogeneous domains. CRM also provides the ability to answer specific questions in the domain using queries written with the CRM vocabulary, which makes it easier to develop applications based on knowledge graphs.
World Journal of Clinical Cases, Volume 9, pp 8773-8781; https://doi.org/10.12998/wjcc.v9.i29.8773

Abstract:
IgG4-related sclerosing cholangitis (IgG4-RSC) is an uncommon benign disease, and its rarer, isolated and mass-forming subtype poses a significant challenge to differential diagnosis from cholangiocarcinoma of the extrahepatic bile duct. We herein report a case of isolated IgG4-RSC with an obstructing bile duct mass, for which extrahepatic bile duct resection was performed under the impression of proximal common bile duct (CBD) cancer. A 79-year-old male was admitted for jaundice that had developed 1 mo prior. There was no family history for autoimmune diseases or biliary cancer. Computed tomography (CT) and magnetic resonance cholangiopancreaticography revealed a short segmental concentric wall thickening of the proximal CBD with diffuse dilatation of the bile duct to the periphery. The endoscopic biopsy specimen showed no malignant cells. Positron emission tomography-CT showed a focal hypermetabolic lesion (SUVmax 4.2) in and around the proximal CBD area. With the impression of proximal CBD cancer, we performed segmental resection of the extrahepatic bile duct. Histopathology demonstrated marked sclerosis with diffuse lymphoplasmacytic infiltration and some eosinophils. Immunohistochemical staining for IgG4 showed increased positivity in some areas (up to 30/high-power field) and IgG4+/IgG+ cell ratio as 30%-50%. Pathologists’ impression was IgG4-related sclerosing disease. Follow-up serum IgG4 levels were continuously elevated; however, no evidence of relapse or other organ involvement related to IgG4-RSC presented. Isolated and mass-forming IgG4-RSC displays striking similarity with cholangiocarcinoma. To avoid unnecessary major surgery, high index of suspicion is needed.
Eun Hyo Jin, Ji Hyun Song, Jooyoung Lee, Jung Ho Bae, Su Jin Chung
World Journal of Clinical Cases, Volume 9, pp 8763-8772; https://doi.org/10.12998/wjcc.v9.i29.8763

Abstract:
Midazolam is commonly used for sedation during gastrointestinal procedures. However, some patients experience paradoxical reactions characterized by excessive movement or excitement. To investigate the rate of recurrence of paradoxical reactions to midazolam during an upper endoscopy. We retrospectively reviewed 122152 sedative endoscopies among a total of 58553 patients at the Seoul National University Hospital, Healthcare System Gangnam Center, from July 2013 to December 2018. Among them, 361 patients with a history of paradoxical reaction during sedative upper endoscopy were enrolled. The characteristics of patients in the recurrent and non-recurrent groups were compared via multivariable analysis using logistic regression. Paradoxical reactions occurred in 0.86% (1054/122152) of endoscopies, and in 1.51% (888/58553) of patients. Among the 361 subjects with previous paradoxical reactions in sedative endoscopies, 111 (30.7%) experienced further paradoxical reactions. Univariable analysis revealed that the total midazolam dose used was higher in the recurrent group (6.74 ± 2.58 mg) than in the non-recurrent group (5.49 ± 2.04 mg; P < 0.0001). Patients were administered a lower dose of midazolam than previous doses: 1 mg less in the recurrent group and 2 mg less in the non-recurrent group. Multivariable analysis showed that the midazolam dose difference was an independent risk factor for recurrent paradoxical reaction (odds ratio: 1.213, 95%CI: 1.099-1.338, P = 0.0001). The rate of recurrence of paradoxical reactions is significantly associated with midazolam dosage. The dose of midazolam administered to patients with previous paradoxical reactions should be less than that previously used.
Michael Wolffsohn
Published: 16 October 2021
Whose Holy Land? pp 47-51; https://doi.org/10.1007/978-3-030-74286-7_8

The publisher has not yet granted permission to display this abstract.
Rüdiger von Nitzsch
Published: 16 October 2021
Entscheidungslehre pp 49-78; https://doi.org/10.1007/978-3-658-34520-4_3

The publisher has not yet granted permission to display this abstract.
Goran Petrović-Lotina
Published: 16 October 2021
Choreographing Agonism pp 107-117; https://doi.org/10.1007/978-3-030-79446-0_7

The publisher has not yet granted permission to display this abstract.
Mohamed-Amine Baazizi, Dario Colazzo, Giorgio Ghelli, Carlo Sartiani,
Emerging Technologies for Education pp 102-112; https://doi.org/10.1007/978-3-030-89022-3_9

The publisher has not yet granted permission to display this abstract.
Muataz Abotabik,
Published: 16 October 2021
by MDPI
Energies, Volume 14; https://doi.org/10.3390/en14206736

Abstract:
This work investigates the fuel energy and emission reductions possible with the hybridization of a Class 8 tractor-trailer. The truck tractor has two drive axles: one powered by an internal-combustion-engine-based powertrain (CP) and the other powered by an electric powertrain (EP) consisting of an electric drive system supplied by a battery pack, resulting in a through-the-road hybrid. The EP has two modes of operation depending on the direction of power flow: motoring/battery discharging and generating/battery recharging. Switched optimal control is used to select between the two modes of EP operation, and a recently developed distributed switched optimal control is applied. The control is distributed between the CP, the EP, and the vehicle motion operation components. Control-oriented, component-specific power flow models are set forth to describe the dynamics and algebraic relationships. Four different tractor-trailers are simulated: the original CP and three hybrids with engine sizes of 15 L, 11 L, and 7 L. Simulations are performed over a short test cycle and two regulatory driving cycles to compare the fuel use, total energy, and emissions. Results show that the hybrids have reduced fuel use, total energy, and emissions compared to the original CP; the reductions and reference velocity tracking error increases as the engine size is decreased. Particularly, fuel use is reduced by at least 4.1% under a charge sustaining operation and by 9.8% when the battery energy can be restored with an off-board charger at the end of the cycle.
Published: 16 October 2021
by MDPI
Nutrients, Volume 13; https://doi.org/10.3390/nu13103624

Abstract:
We previously reported the potential anti-obesity effects of the water extract of Hydrangea serrata (Thunb.) Ser. leaves (WHS) in high-fat diet-induced obese mice. As an extension of our previous study, we investigated the anti-adipogenic and anti-obesity effects of WHS and its underlying molecular mechanisms in 3T3-L1 preadipocytes and genetically obese db/db mice. WHS attenuated the gene expression of adipogenic transcription factors, CCAAT/enhancer binding protein (C/EBP)α, peroxisome proliferator-activated receptor (PPAR)γ, and sterol regulatory element binding protein (SREBP)-1. Moreover, WHS inhibited the mitotic clonal expansion of preadipocytes by inducing G1 cell cycle arrest. Oral administration of WHS alleviated body weight gain and body fat accumulation in vivo. In addition, adipocyte hypertrophy and liver steatosis were ameliorated by WHS treatment. WHS reduced C/EBPα, PPARγ, and SREBP-1 expression and activated AMPKα phosphorylation in both white adipose tissue (WAT) and liver tissue. WHS also mildly upregulated the expression of thermogenic proteins, including uncoupling protein-1, PPARs, PPARγ coactivator-1α, and sirtuin-1, in brown adipose tissue (BAT). Furthermore, WHS altered the gut microbiota composition to resemble that of wild-type mice. Taken together, our findings suggest that WHS could alleviate adiposity by inhibiting adipogenesis in WAT and the liver and modulating the gut microbiota.
Michael Wolffsohn
Published: 16 October 2021
Whose Holy Land? pp 53-93; https://doi.org/10.1007/978-3-030-74286-7_9

The publisher has not yet granted permission to display this abstract.
Published: 16 October 2021
by MDPI
Sustainability, Volume 13; https://doi.org/10.3390/su132011436

Abstract:
The aim of this study was to analyze the influence of values and social environmental factors on the pro-environmental attitudes of students. A representative survey of 1161 Lithuanian schoolchildren was conducted between October and November 2020. Health was the most important value for students, and for girls, while healthcare was more important for boys. Among the ecological values, unpolluted food, clean air, and fresh water were the most important. For Lithuanian students, school does not play a decisive role in outdoor behavior compared to family, which plays a more important role in outdoor behavior, and friends are the most important influencers of outdoor behavior. Students in Lithuania have a pro-ecological outlook, which is shaped by their interest in and practice of ecology. Students of ECO schools are more responsible than students of regular schools, although they have less pro-environmental attitudes compared to students of regular schools.
Emmanuel Saffa Abdulai
Freedom of Information Law and Good Governance pp 27-35; https://doi.org/10.1007/978-3-030-83658-0_2

The publisher has not yet granted permission to display this abstract.
Published: 16 October 2021
by MDPI
Journal of Fungi, Volume 7; https://doi.org/10.3390/jof7100869

Abstract:
In this work we analyzed the relationship among native arbuscular mycorrhizal fungi (AMF) and vine roots affected by esca, a serious grapevine trunk disease. The AMF symbiosis was analyzed on the roots of neighboring plants (symptomatic and asymptomatic to esca) in 14 sites of three vineyards in Marche region (central–eastern Italy). The AMF colonization intensity, identified by non-vital staining, showed higher value in all esca symptomatic plants (ranging from 24.6% to 61.3%) than neighboring asymptomatic plants (from 17.4% to 57.6%). The same trend of Glomeromycota phylum abundance was detected by analyzing fungal operational taxonomic units (OTUs) linked to the AMF community, obtained by amplicon high throughput analysis of ITS 1 region. Overall, the highest amount of OTUs was detected on roots from symptomatic plants (0.42%), compared to asymptomatic roots (0.29%). Specific primer pairs for native Rhizophagus irregularis and Funneliformis mosseae AMF species, were designed in 28S rRNA and large subunit (LSU) ribosomal RNA, respectively, and droplet digital PCR protocol for absolute quantification was set up. A higher number of DNA copies of both fungal species were detected more frequently in symptomatic than asymptomatic vines. Our study suggests a relationship between esca and native AMF in grapevine. These results underline the importance of native rhizosphere microbial communities for a better knowledge of grapevine esca disease.
Published: 16 October 2021
by MDPI
International Journal of Molecular Sciences, Volume 22; https://doi.org/10.3390/ijms222011165

Abstract:
One of the most favored trends in modern agriculture is biological control. However, many reports show that survival of biocontrol bacteria is poor in host plants. Providing biocontrol agents with protection by encapsulation within external coatings has therefore become a popular idea. Various techniques, including extrusion, spray drying, and emulsion, have been introduced for encapsulation of biocontrol bacteria. One commonly used biopolymer for this type of microencapsulation is alginate, a biopolymer extracted from seaweed. Recent progress has resulted in the production of alginate-based microcapsules that meet key bacterial encapsulation requirements, including biocompatibility, biodegradability, and support of long-term survival and function. However, more studies are needed regarding the effect of encapsulation on protective bacteria and their targeted release in organic crop production systems. Most importantly, the efficacy of alginate use for the encapsulation of biocontrol bacteria in pest and disease management requires further verification. Achieving a new formulation based on biodegradable polymers can have significant effects on increasing the quantity and quality of agricultural products.
Published: 16 October 2021
Integralrechnung leicht gemacht! pp 135-176; https://doi.org/10.1007/978-3-662-63586-5_5

The publisher has not yet granted permission to display this abstract.
Fabian Bickel
Published: 16 October 2021
Customs Unions in the WTO pp 261-271; https://doi.org/10.1007/978-3-030-86312-8_7

The publisher has not yet granted permission to display this abstract.
Published: 16 October 2021
by MDPI
Abstract:
Persistent pain following treatment for breast cancer is common and often imprecisely labeled as post-mastectomy pain syndrome (PMPS). PMPS is a disorder with multiple potential underlying causes including intercostobrachial nerve injury, intercostal neuromas, phantom breast pain, and pectoralis minor syndrome. Adding further complexity to the issue are various musculoskeletal pain syndromes including cervical radiculopathy, shoulder impingement syndrome, frozen shoulder, and myofascial pain that may occur concurrently and at times overlap with PMPS. These overlapping pain syndromes may be difficult to separate from one another, but precise diagnosis is essential, as treatment for each pain generator may be distinct. The purpose of this review is to clearly outline different pain sources based on anatomic location that commonly occur following treatment for breast cancer, and to provide tailored and evidence-based recommendations for the evaluation and treatment of each disorder.
Published: 16 October 2021
by MDPI
Sensors, Volume 21; https://doi.org/10.3390/s21206867

Abstract:
Autonomous Driver Assistance Systems (ADAS) are of increasing importance to warn vehicle drivers of potential dangerous situations. In this paper, we propose one system to warn drivers of the presence of pedestrians crossing the road. The considered ADAS adopts a CNN-based pedestrian detector (PD) using the images captured from a local camera and to generate alarms. Warning messages are then forwarded to vehicle drivers approaching the crossroad by means of a communication infrastructure using public radio networks and/or local area wireless technologies. Three possible communication architectures for ADAS are presented and analyzed in this paper. One format for the alert message is also presented. Performance of the PDs are analyzed in terms of accuracy, precision, and recall. Results show that the accuracy of the PD varies from 70% to 100% depending on the resolution of the videos. The effectiveness of each of the considered communication solutions for ADAS is evaluated in terms of the time required to forward the alert message to drivers. The overall latency including the PD processing and the alert communication time is then used to define the vehicle braking curve, which is required to avoid collision with the pedestrian at the crossroad.
Published: 16 October 2021
by MDPI
Abstract:
Multi-axis Laser Engraving Machine Tools (LEMT) are widely used in precision processing of parts with complex surface. The accuracy of kinematic model and parameter measurement are the key factors determining the processing quality of LEMT. In this paper, a kinematic model of multi-axis LEMT was established based on Homogeneous Transformation Matrix (HTM). Two types of unknown parameters, linkage parameters and positioning parameters, were measured in the presented model. Taking advantage of the characteristics of laser processing, this paper proposed a rapid measurement method of linkage parameters by combining the machine tool motion with the laser marking action. For positioning parameters, this study proposed a non-contact measurement method based on structured light scanner, which can obtain the translation values and the rotation values from the Workpiece Coordinate System (WCS) to the Basic Coordinate System (BCS) simultaneously. After the measurement of two kinds of parameters of a multi-axis LEMT was completed, the processing of a spatial curve was performed and the average contour error was controlled at 15.1 µm, which is sufficient to meet the project requirements.
Published: 16 October 2021
by MDPI
Abstract:
Actinium-225 (225Ac) is a promising radionuclide used in targeted alpha therapy (TAT). Although 225Ac labeling of bifunctional chelating ligands is effective, previous in vivo studies reported that free 225Ac can be released from the drugs and that such free 225Ac is predominantly accumulated in the liver and could cause unexpected toxicity. To accelerate the clinical development of 225Ac TAT with a variety of drugs, preparing methods to deal with any unexpected toxicity would be valuable. The aim of this study was to evaluate the feasibility of various chelators for reducing and excreting free 225Ac and compare their chemical structures. Nine candidate chelators (D-penicillamine, dimercaprol, Ca-DTPA, Ca-EDTA, CyDTA, GEDTA TTHA, Ca-TTHA, and DO3A) were evaluated in vitro and in vivo. The biodistribution and dosimetry of free 225Ac were examined in mice before an in vivo chelating study. The liver exhibited pronounced 225Ac uptake, with an estimated human absorbed dose of 4.76 SvRBE5/MBq. Aminopolycarboxylate chelators with five and six carboxylic groups, Ca-DTPA and Ca-TTHA, significantly reduced 225Ac retention in the liver (22% and 30%, respectively). Significant 225Ac reductions were observed in the heart and remainder of the body with both Ca-DTPA and Ca-TTHA, and in the lung, kidney, and spleen with Ca-TTHA. In vitro interaction analysis supported the in vivo reduction ability of Ca-DTPA and Ca-TTHA. In conclusion, aminopolycarboxylate chelators with five and six carboxylic groups, Ca-DTPA and Ca-TTHA, were effective for whole-body clearance of free 225Ac. This feasibility study provides useful information for reducing undesirable radiation exposure from free 225Ac.
Mukhammad Fakhrizal Baihaqi
Published: 16 October 2021
Abstract:
Permasalahan sampah sudah sangat umum dimata masyarakat khususnya di daerah pinggiran kota atau di daerah perdesaan. Dari sampah tersebut menimbulakan masalah salah satunya banjir yang merebak menjadi penyakit dimana menimpa masyarakat. Mulai dari gatal-gatal, diare, dbd, dll. Sebaiknya kita sebagai warga negara Indonesia yang berbudi luhur seharusnya tidak membuang sampah disungai ataupun di pinggiran sungai agar disaat musim penghujan tidak terjadi banjir yang dapat menimbulkan penyakit. Solusi yang tepat untuk permasalahan sampah sendiri juga harus diperhatikan agar tepat dan masyarakat mendapat dampak baik dari solusi tersebut.
Hiroki Otsuka, Atsushi Kobayashi, Masaki Yoshida, Masako Kato
Dalton Transactions; https://doi.org/10.1039/d1dt02824c

Abstract:
We newly synthesised oxygen-evolving molecular Ru(II) catalysts with one or two carbazole moieties on the axial pyridyl ligands, namely [Ru(bda)(cbz-py)(py)] and [Ru(bda)(cbz-py)2] [C1 and C2; bdaH2 = 2, 2’-bipyridyl-6, 6’-dicarboxylic acid; py = pyridine, cbz-py = 9-(pyridin-4-yl)-9H-carbazole] to investigate the effect of cbz modification on the photophysical and catalytic properties of the well-known molecular catalyst [Ru(bda)(py)2] (C0). The initial oxygen-evolving catalytic activities of C1 and C2 were higher than that of C0 in both a chemical reaction driven by the strong oxidant (NH4)2[Ce(NO3)6] (CAN = Ceric ammonium nitrate) and a photochemical oxidation using a [Ru(bpy)3]2+ (bpy = 2,2’-bipyridine) photosensitiser with Na2S2O8 as the sacrificial oxidant. The higher activities were ascribed to the electron-withdrawing cbz groups, which promoted the radical coupling reaction to form a RuIV–O–O–RuIV species. A unique oxygen-evolution rate change behaviour was observed for both C1 and C2 in the presence of a large excess of CAN, suggesting competitive oxidation of the cbz moiety during the chemical oxygen evolution reaction. This work suggests that cbz modification of an oxygen evolution molecular catalyst is a promising approach to integrate the hole accumulator near the oxygen evolution catalytic centre.
Levent Çalli, Fatih Çalli, Büşra Alma Çalli
MANAS Sosyal Araştırmalar Dergisi, Volume 10, pp 2355-2372; https://doi.org/10.33206/mjss.894809

Abstract:
Yönetim Bilişim Sistemlerinin etkilendiği branşlar, alanda geliştirilen teoriler ve var olan konu çeşitliliklerinin belirlenmesi bir disiplin olarak tanımlandığı ilk günden bu yana akademik literatürde yoğun olarak tartışılan bir konudur. Bu araştırmada, Türkiye’de hızlı ve dinamik bir gelişim gösteren YBS anabilim dalında 2002-2020 yılları arasında tamamlanan 574 lisansüstü tez özeti metin madenciliği yöntemi olan Gizli Dirichlet Ayrımı algoritmasıyla analiz edilmiştir. Analiz sonucunda tezlerin; e-Ticaret ve Pazarlama, Sistem Geliştirme ve Etkileri, Bilişim Sistemleri’nin Organizasyonlara Etkileri, Veri Madenciliği, İnsan Kaynakları Yönetimi, Organizasyonel Değişim, Alana Özel Çalışmalar I, Alana Özel Çalışmalar II, Güvenlik, Eğitim ve Öğretim, Tahmin ve Karar Destek olmak üzere 11 farklı konu başlığı altında kümelenebileceği öngörülmektedir. Araştırma kapsamında, tahmin sonuçlarının ulusal ve uluslararası literatürle göstermiş olduğu benzerlikler ve farklılıklar tartışılmıştır. Araştırma sonucunda yönetim bilişim sistemleri üzerine çalışma yapmak isteyen araştırmacılara fikir vermek ve yol göstermek hedeflenmiştir. The disciplines that affect the theories developed in the field, and the identification of the existing topic diversity have all been extensively discussed in the academic literature since the Management Information Systems (MIS) was first defined as a discipline. In this study, 574 postgraduates’ theses completed between 2002 and 2020 in the Department of MIS were analyzed using the Hidden Dirichlet Discrimination algorithm, which is a text mining method. As a result of the analysis, it is predicted that postgraduates’ theses can be clustered under 11 topics, are e-Commerce and Marketing (K1), System Development and Effects (K2), Effects of Information Systems on Organizations (K3), Data Mining (K4), Human Resources Management (K5), Organizational Change (K6), Field-Specific Studies I (K7), Field-Specific Studies II (K9), Security (K8), Education and Training (K10), Forecasting and Decision Support (K11). The similarities and differences of the results are discussed in the context of the national and international literature. As a result of the research, it was aimed to give an idea and guide the researchers who want to study on management information systems.
Isabelle Sirois, Maxim Isabelle, Jérôme D. Duquette, Frederic Saab, Etienne Caron
Published: 16 October 2021
Abstract:
Immunopeptidomics is an emerging field that fuels and guides the development of vaccines and immunotherapies. More specifically, it refers to the science of investigating the composition of peptides presented by major histocompatibility complex (MHC) class I and class II molecules using mass spectrometry (MS) technology platforms. Among all the steps in an MS-based immunopeptidomics workflow, sample preparation is critically important for capturing high-quality data of therapeutic relevance. Here, step-by-step instructions are described to isolate MHC class I and II-associated peptides by immunoaffinity purification from quality control samples, from mouse (EL4 and A20), and human (JY) cell lines more specifically. The various reagents and specific antibodies are thoroughly described to isolate MHC-associated peptides from these cell lines, including the steps to verify the beads-binding efficiency of the antibody and the elution efficiency of the MHC-peptide complexes from the beads. The protocol can be used to establish and standardize an immunopeptidomics workflow, as well as to benchmark new protocols. Moreover, the protocol represents a great starting point for any non-experts in addition to foster the intra- and inter-laboratory reproducibility of the sample preparation procedure in immunopeptidomics.
Yuta Yamamoto, Koji Kimura, Artoni Kevin R. Ang, Yasushi Hirose, Kouichi Hayashi
e-Journal of Surface Science and Nanotechnology, Volume 19, pp 99-103; https://doi.org/10.1380/ejssnt.2021.99

Abstract:
Research of oxynitrides is a new trend in developing new functional material. Getting information about the local structure around the cation is crucial because the arrangement of the anions affects the cations and the displacement of cations can be related to their physical properties. To study the effects of mixed anions on the behavior of the cations in oxynitrides, we applied X-ray fluorescence holography on a CaTaO2N thin film. Atomic images reconstructed from Ta Lα holograms clearly showed the atomic positions around Ta. By comparing the intensities of the Ta and Ca atomic images, we found that the fluctuations of the Ta atoms are larger than the Ca atoms.
Deman Tang,
MATLAB Codes for Finite Element Analysis pp 663-715; https://doi.org/10.1007/978-3-030-74236-2_15

The publisher has not yet granted permission to display this abstract.
Idil Aydin, Aysun Bozanta, Mucahit Cevik, Ayse Basar
Published: 16 October 2021
Abstract:
In this research, we aim to forecast the trajectory of the COVID-19 pandemic in terms of the number of exposed, infected, vaccinated, hospitalized, recovered, and dead people, and observe the effects of different vaccination strategies on the spread of the COVID-19. We simulate the ongoing trajectory of the outbreak in three countries, namely, Canada, the UK, and Israel using the susceptible - vaccinated - exposed - infected - critical - recovered - dead (SVEICRD) model. We consider two vaccination strategies and investigate their effects on the number of exposed and death cases. We perform an extensive numerical study to assess the implications of different strategies and spread scenarios. Our findings confirm that the fourth wave has begun in all three countries, and already reached its peak. We observe that starting second dose vaccination as early as possible is the most effective in mitigating the spread of COVID-19, although it does require more vaccination supply than the alternative strategies. Our results show that the SVEICRD model successfully forecasts the changing number of people in each compartment and the vaccination strategy significantly impacts the trajectory of the outbreak.
, Tandong Yao, Yongjian Ding, Jiawen Ren
Published: 16 October 2021
Governance in Transition pp 1-32; https://doi.org/10.1007/978-981-16-6425-0_1

The publisher has not yet granted permission to display this abstract.
Published: 16 October 2021
Abstract:
We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of EF-hand calcium binding domain 4A, encoded by EFCAB4A when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, EFCAB4A expression was correlated with recurrence-free survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. EFCAB4A may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.
Published: 16 October 2021
Abstract:
We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of KIAA1009, encoded by KIAA1009 when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, KIAA1009 expression was correlated with distant metastasis-free survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. KIAA1009 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.
Hibur Wanti
Published: 16 October 2021
Abstract:
AbstrakPernikahan dan keluarga merupakan lembaga yang sudah ditetapkan oleh Allah. Allah sendiri telah memberikan masing-masing tugas dan tanggung jawab bagi pribadi dalam rumah tangga itu. Tujuan pernikahan Kristen untuk mencapai Misi Allah dalam dunia ini. Namun tujuan itu tidak akan tercapai apabila dasar dalam keluarga tidak sesuai dengan kehendak Allah. pasalnya, banyak keluarga kristen yang saat ini tidak lagi berjalan di atas dasar Kristus. Jalan yang ditempuh suami istri untuk menjadikan rumah tangga harmonis sering kali keliru. Akibatnya tidak sedikit yang harus berhenti karena dasar yang tidak di bangun berdasarkan kehendak Allah. apa yang menjadi dasar dalam membangun keluarga Kristen ? bagaimana seharusnya peran suami dan istri menurut kehendak Allah ? oleh karena itu, permasalahan yang muncul dalam penulisan ini adalah bagaimana ‘‘Teologi Paulus dalam konsep pernikahan Kristen berdasarkan Efesus 5:22-33 dan implikasi teologis bagi iman keluarga Kristen’’. Metode penulisan yang digunakan adalah penulisan kualitatif dengan memakai pendekatan literatur yakni kajian gramatikal/historikal. Hasil dari pembahasan ini adalah bahwa dasar dari keluarga Kristen adalah Landasan Kasih antara suami dan istri dalam membagun hubungan yang dikehendaki Tuhan. Istri tunduk kepada suami dan suami mengasihi istri.
Tuğba GÜNGÖR
MANAS Sosyal Araştırmalar Dergisi, Volume 10, pp 2243-2255; https://doi.org/10.33206/mjss.893401

Abstract:
Birey her zaman kendini ifade etme arayışı içerisinde olmuş ve iletişim kurma yetisine yönelik birçok yöntem geliştirmiştir. Sanat gibi özel bir alanının keşfiyle gelişen süreçte, eserlerin çıkış kaynağına sanatçının yerel değerlerde gelişen çevresine dair gözlemleri, yaşanmışlıkları ve günlük yaşam dinamikleri referans olabilmektedir. Bir gelenek yapısı ve gıda, giyim, araç ve gereç gibi günlük temel ihtiyaçların karşılanmasında etkinlik alanı olan pazar yerleri sanatçının eserlerinde bir kültürel değer ve kültürler arası diyaloğu sağlayan unsur olarak kendi konumunu alabilmektedir. Çalışmada Çağdaş Türk Resim Sanatında varlığıyla kendini somutlaştıran “pazar yeri” temalı eserler, plastik yaklaşımlar ve kültürel etkileşim noktaları açısından irdelenmiştir. Bu yolla kültürel bir dokuyu ifade eden pazar yeri temasının, eserlerdeki vücut bulma biçemleriyle varlığı sorgulanmıştır. The individual has always been searching for self-expression and has developed many methods for the ability to communicate. In the process that advances with the discovery of a particular field such as art, the artist's observations, experiences and daily life dynamics of the artist's environment that develops in local values can be a reference to the origin of the works. Bazaar, which is a traditional structure and an activity area for meeting daily basic needs such as food, clothing, tools, and equipment, can take their position as a cultural value and intercultural dialogue in the artist's works. In this study, the "bazaar" themed works that embody themselves in Contemporary Turkish Painting Art are examined in terms of plastic approaches and cultural interaction points. The existence of the bazaar theme, which expresses a cultural texture in this way, has been questioned with it styles in the artistic works.
Published: 16 October 2021
by MDPI
Mathematics, Volume 9; https://doi.org/10.3390/math9202606

Abstract:
In this study, we firstly obtain De Moivre-type identities for the second-order Bronze Fibonacci sequences. Next, we construct and define the third-order Bronze Fibonacci, third-order Bronze Lucas and modified third-order Bronze Fibonacci sequences. Then, we define the generalized third-order Bronze Fibonacci sequence and calculate the De Moivre-type identities for these sequences. Moreover, we find the generating functions, Binet’s formulas, Cassini’s identities and matrix representations of these sequences and examine some interesting identities related to the third-order Bronze Fibonacci sequences. Finally, we present an encryption and decryption application that uses our obtained results and we present an illustrative example.
Rüdiger von Nitzsch
Published: 16 October 2021
Entscheidungslehre pp 175-203; https://doi.org/10.1007/978-3-658-34520-4_9

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Goran Petrović-Lotina
Published: 16 October 2021
Choreographing Agonism pp 119-134; https://doi.org/10.1007/978-3-030-79446-0_8

The publisher has not yet granted permission to display this abstract.
Rüdiger von Nitzsch
Published: 16 October 2021
Entscheidungslehre pp 149-173; https://doi.org/10.1007/978-3-658-34520-4_8

The publisher has not yet granted permission to display this abstract.
Goran Petrović-Lotina
Published: 16 October 2021
Choreographing Agonism pp 1-16; https://doi.org/10.1007/978-3-030-79446-0_1

The publisher has not yet granted permission to display this abstract.
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