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Brijesh K, Nesari Tanuja, Mallya Suma V, Kamath Madhusoodan
International Journal of Pharmacognosy and Life Science, Volume 1, pp 18-23; https://doi.org/10.33545/27072827.2020.v1.i2a.13

Abstract:
Materials and Methods: Inflorescences of test drug separated from their colourful bracts shade dried for a day and cut in to small piece. For HPTLC n-hexane extract of this sample was applied on a precoated aluminium plates using Benzene as mobile phase. Developed plates were visualized in UV 254, 366, under white light and then derivatised with vanillin sulphuric acid and scanned under UV 254 and 366 nm. Methylated volatile oil of test sample was introduced into a stream of helium, for Gas Chromatography study. The results were tabulated as per the retention time. Results: HPTLC photo documentation of n-hexane extract of drug has shown 5 peaks at 254nm, whereas 6 peaks at 366nm. After post derivatisation at 620nm drug has shown 9 peaks. GC-MS analysis of volatile oil of test drug showed presence of totally 39 compounds among which 32 were identified by their Mass spectra with MS-Library.
Hamida AL Barasi, Samia Elzwi
International Journal of Pharmacognosy and Life Science, Volume 1, pp 14-17; https://doi.org/10.33545/27072827.2020.v1.i2a.12

Abstract:
Cinnamon is a small evergreen tree 10-15 meters tall, belongs to the family Lauracae. The leaves are ovate-oblong in shape, 7-18 Cm long, the flowers which are arranged in panicles, have greenish color and distinct odor. The fruit is a purple one centiberry containing a single seed. Cinnamon are widely used as spice and flavoring agent and can be clinically used in treatment of certain diseases such as type 2 diabetes mellitus. Cinnamon extract has blood glucose lowering effect in patients with type 2 diabetes. This study tested the effect of cinnamon extract on D- glucose induced hyperglycemias which showed significant reduction in plasma glucose level. Chronic hyperglycemia model induced by a single intraperitoneal injection of streptozotocin, the extract showed marked decrease in blood glucose level.
Fatema Shorna, Shifat Sehrin Khan Upoma, Timothy Singh, Pritesh Ranjan Dash
International Journal of Pharmacognosy and Life Science, Volume 2, pp 01-10; https://doi.org/10.33545/27072827.2021.v2.i1a.21

Abstract:
The sudden and unexpected outbreak of SARS-Covid-2 also known as Severe Acute Respiratory Syndrome- Corona virus disease-2 has nearly killed 2.86M people worldwide and approximately affected 132M lives, thus for humans the situation has become catastrophic. The situation now has become more serious and severe considering the SARS-COV spread in 2003 from camels. A cure or a vaccine still look distant but scientists are working to better understand this virus. Four new studies about the coronavirus have come to light. Thailand has reported the first case of covid-19 transmission from a dead patient to a health worker. The medical examiner died after catching the infection from a dead body. This raises the concern over the risk faced by both working in morgues and funeral rooms. It is still not known how long the virus survives in a dead body. Heat does not kill or deactivate the corona virus. A Chinese study has found that the direction of air conditioning is a key factor for droplet transmission. Governments from many parts of the world are extending restrictions. How long will this last? Turns out one-time lockdown might not be enough to clamp down on the coronavirus. In fact, the scientists said that the Harvard University say that repeated periods of social distancing might be required till 2022. In comparison to all the articles and journals published on this emerging topic, our journal focuses on the history of COVID-19, its pathogenesis, its available treatment regimens, the different ways the virus was found to spread and its future prospects. We have summarized the findings in this paper. The main objective of our paper was to portray all the updated information on this emerging topic to inform and aware people of the future which is yet to come because of this sudden pandemic.
Nema Ram, Gk Singh, Pk Desai, Ashwin Singh Chouhan
International Journal of Pharmacognosy and Life Science, Volume 2, pp 57-60; https://doi.org/10.33545/27072827.2021.v2.i1a.28

Abstract:
This ethno-botanical study describes the traditional knowledge related to the use of Dipcadi erythraeum used by the tribes and communities residue in the Great Indian Desert or Indian Thar Desert. Dipcadi erythraeum (synonym- Dipcadi unicolor, Ornithogalum erythraeum, Uropetalon erythraeum, Uropetalon unicolor, Uropetalum unicolor) also known for Jangli Dungri is recently belonging to the subfamily Scilloideae of the family Asparagaceae and mainly found in rocky and gravelly habitats having greater medicinal values such as leaves are laxatives, used as an ointment for wounds, while whole plant is used for cough, biliousness, diabetes, urinary and discharge. This paper also deals with the focus on conservation of Dipcadi erythraeum because Due to soil erosion, over exploitation of rocks and hills, over grazing, habitat loss Dipcadi erythraeum is recently categorized as rare, endangered and threatened plant by IUCN (International Union for Conservation of Nature) and WCMC (World Conservation Monitoring System).
Okorie Ndidiamaka Hannah, Ali Ibeabuchi Jude
International Journal of Pharmacognosy and Life Science, Volume 2, pp 67-71; https://doi.org/10.33545/27072827.2021.v2.i1a.30

Abstract:
Triclisia marcrophylla is a climbing plant used in Nsukka in the treatment of gastrointestinal disorder. This research was designed to study the phytochemical constituents and antibacterial activity of T. macrophylla ethanol leaf extract. Cold maceration method was used to get the ethanol extract. Standard qualitative and quantitative phytochemical analysis methods were used for the phytochemical estimation. The antibacterial activity was determined using agar well diffusion method. The result of the phytochemical screening showed the presence of alkaloids, flavonoids, tannins, cardiac glycosides, steroids, terpenoids, reducing sugar and saponins. The percentage yield of the estimated phytoconstituents gives 6% alkaloids, 1.2% flavonoids, 0.48% cardiac glycosides and 2% saponins respectively. The ethanol extract showed zone of inhibition ranging from 2 mm to 15.7 mm against Escherichia coli, Bacillus subtilis, Klebsiella pneumonia, Enterococcus faecalis while staphylococcus and Pseudomonas aeruginosa where not inhibited at any concentration. The extract demonstrated highest activity against Klebsiella pneumonia and Enterococcus faecalis. Conversely, the extract showed promising antibacterial activity and might be useful alternative in controlling disease caused by pathogenic organisms. The finding validated the folkloric claims of the plant use in treating infectious diseases.
Rajapaksha Gedara Weranga Dhanushka Bandara Rajapaksha1, Athige Rajith Neloshan Silva, Wanigasekara Daya Ratnasooriya, Bulathwelage Anton Rohan Fernando, Thennakoon Mudiyanselage Aravinda Bandara Thennakoon, Sanjeewa Singhabahu
International Journal of Pharmacognosy and Life Science, Volume 1, pp 42-50; https://doi.org/10.33545/27072827.2020.v1.i1a.9

Abstract:
This study evaluated in vitro antibacterial activity and phytochemical profile of four plants
Charu Bansal, Rachna Jain, Umesh Shukla, Smita Paul
International Journal of Pharmacognosy and Life Science, Volume 1, pp 01-05; https://doi.org/10.33545/27072827.2020.v1.i2a.10

Abstract:
Diabetes mellitus is a fastest growing serious global health problem. In 2000, India with 31.7 million diabetic population topped the world followed by China (20.8 million) respectively. Poor glycaemic control has been observed in the Indian diabetic population which in long term lead to various micro and macro vascular complications. Diabetes is one of four priority non-communicable diseases (NCDs) targeted by all health agencies for the Prevention and Control of NCDs. Turmeric (Curcuma longa) and Indian Gooseberry (Emblica officinalis) powder in combination called as Nisha Amalaki Churna showed significant hypoglycemic, antioxidant and hyperlipidemia effect in many experimental and human research. Ayurveda strongly recommended its significant effect in the management of diabetes (Prameha). The present write up is an effort to discuss the opportunities of an effective herbal combination Nishamalaki Churna as preventive and health promotive dimensions in Type 2 Diabetes Mellitus.
Gaurava Srivastav, Dakshina Gupta
International Journal of Pharmacognosy and Life Science, Volume 2, pp 44-48; https://doi.org/10.33545/27072827.2021.v2.i1a.26

Abstract:
The goal of this article is to use scholarly search engines like PubMed and Scifinder to find scholarly articles and reports on Cinnamon, its novel implications, preparation, analysis, and use in the management and cure of serious illnesses like diabetes, cardiovascular disease, Alzheimer's disease, and cancer. Cinnamon has long been used in food preparations and as a herbal medication to treat a wide range of diseases and symptoms. Cinnamon has antioxidant, antibacterial, anti-inflammatory, and other medicinal effects. New research not only demonstrates the value of cinnamon as a flavor, but also suggests that it could be used as a natural treatment for significant ailments like type 2 diabetes, chronic digestive issues, cardiovascular disease, cancer, and Alzheimer's disease. This article examines the botanical, chemical, and pharmacological properties of cinnamon in depth.
Rani Dinesh Gupta, Samiksha A Mahant, Pratik R Wankhade, Atul T Hemke, Kamlesh J Wadher, Milind J Umekar
International Journal of Pharmacognosy and Life Science, Volume 2, pp 49-56; https://doi.org/10.33545/27072827.2021.v2.i1a.27

Abstract:
Gallic acid, also known as 3, 4, 5-trihydroxybenzoic acid, is a naturally occurring secondary metabolite that can help biological cells, tissues, and organs resist oxidative stress. It has significant antioxidant and free radical scavenging characteristics and may be extracted from a range of fruits, plants, and nuts. GA is a phenolic substance present in a variety of fruits and medicinal plants. In a number of plants, it can be present in phytoconstituents like free acids, esters, catechin derivatives, and hydrolysable tannins GA has been reviewed by evaluating information on the Internet (using Google Scholar, CAB Abstracts, Elsevier, Cambridge University Press, JSTOR, Nature Publishing and Science online) and in libraries. Traditional medicinal uses of were recorded in the Ayurveda and Chinese pharmacopeia. The present review study covered chemical constituents and pharmacological properties. This has included GA therapeutic effects of the whole plants and its extracts, fractions and isolated compounds are Antioxidant, Antimicrobial, Anticancer, Antidiabetic Analgesic and Anti-inflammatory, Wound Healing, Hepatoprotective, Cardiovascular, Gastrointestinal, Metabolic, Neuropsychological, Allergic skin disease, Antidepressant, Diuretic, Antifungal, Anthelmintic, Antianxiety activities have all been described and GA's safety and therapeutic efficacy in humans must be further defined through future research.
Chetna M Sangode, Pranjal C Tidke, Milind J Umekar
International Journal of Pharmacognosy and Life Science, Volume 2, pp 11-17; https://doi.org/10.33545/27072827.2021.v2.i1a.22

Abstract:
Ehretia laevis is a rare Indian medicinal plant used from ancient times. The plant is used for a variety of purposes, including ornaments, pot herbs, wood and stone dye, medicines, wines, and cosmetics. The inner bark of Ehretia laevis Roxb is used in the treatment of ulcers and headaches. Also useful in treatment for schizophrenia, absorption of calcium, muscle protein, post-surgery recovery, sports injuries, production of hormones, enzymes, antibodies. The plant has many uses that that many uses for different medicinal purposes. The fresh root is used in the treatment of syphilis, and the root is also used to treat diphtheria. Leaf powder mixed with sugar is divided into 10 equal doses. Each dose is taken daily along with goat milk curd to healing dysuria. The review focusing on the pharmacognostic parameters of E. Laevis and pharmacological uses.
Rasika J Patil, Samiksha M Nikam, Priya S Milmile, Nishant B Awandekar, Milind J Umekar
International Journal of Pharmacognosy and Life Science, Volume 2, pp 61-66; https://doi.org/10.33545/27072827.2021.v2.i1a.29

Abstract:
Migraine is a debilitating neurovascular disorder with a number of targeted, tolerant and effective treatments. The formulation made in plant-based plants, holds great promise in the identification of new therapeutic goals for migraine. Therefore, safety and performance tests are essential. We are reviewing some of the phytomedicines that may be useful in the treatment of migraine-feverfew (Tanacetum Parthenium), butterbur (Petasites hybridus), menthol (Mentha piperita), coriander (C. sativum), Ginkgobiloba (Gingko macrophylla K. Koch), Ginger (Zingiber officinale Rosc.), Matricaria chamomilla (Matricaria recutita), Curcumin (Curcuma longa), Lavender (Lavandula spica) in terms of their mechanisms and evidence of migraine treatment. The results of this systematic review suggest that many herbal remedies, through their many physiological influences, emerge as options for improving migraine treatment. However, other high-level studies are important to evaluate their effectiveness and safety as a treatment for migraine.
Ashaq Hussain Bhat, Samiea Hussein
International Journal of Pharmacognosy and Life Science, Volume 1, pp 55-58; https://doi.org/10.33545/27072827.2020.v1.i1a.31

Abstract:
By injecting the colloidal carbon particles, the mononuclear phagocyte system in Schizothorax niger was studied in vivo. As per results the major organs of carbon particle localization in Schizothorax niger after studying histology of organs from 2 hours to day 8 were kidney, spleen, thymus and heart. Spleen was seen with highest density of carbon particles followed by the kidney. The medulla of the thymus was seen first with antigen trapping ability followed by the cortex after day 4. The ventricular endocardial cells of heart were seen as Immunocompetent. Uptake of carbon particles by the monocytes was seen upto day 2.
Lissette H Degla, Pascal A Olounlade, Sabbas Attindehou, Mawule S Hounzangbe-Adote, Latifou Lagnika
International Journal of Pharmacognosy and Life Science, Volume 2, pp 01-05; https://doi.org/10.33545/27072827.2021.v2.i2a.32

Abstract:
The essential oils from Ocimum gratissimum, Hyptis suaveolens (Lamiceae) and Psidium guajava (Myrtaceae) have biological properties. The aim of this work is to compare the effect of essential oils of these three medicinal plants on weight growth, hematological and biochemical parameters of treated rats through the procedure of acute toxicity evaluation on Wistar rats. The doses applied are 100, 250 and 500mg/Kg bw for each of the essential oils From the results obtained, the effects of essential oils of Ocimum gratissimum, Hyptis suaveolens and Psidium guajava leaves on biochemical, hematological parameters and weight growth of rats are dose dependent. At the dose of 500mg/Kg bw, they significantly increased the rate of white blood cells, urea, creatinemia, transaminases and reduced the weight growth of rats by more than 10% (p
Heh Perera, Rs Maddumage, Rsp Fernando, Wd Ratnasooriya, Rn Pathirana, Arn Silva
International Journal of Pharmacognosy and Life Science, Volume 1, pp 24-28; https://doi.org/10.33545/27072827.2020.v1.i2a.14

Abstract:
In vitro antibacterial potential of aqueous extracts of Heteropogon contortus (whole plant, leaves, flowers, stem and roots) were examined against gram negative and positive pathogen; Escherichia coli (ATCC 25922) and Staphylococcus aureus (ATCC 25923) respectively. Concentrations tested were 100 and 200 mg/mL, using agar well diffusion bioassay technique. Gentamicin (1µg/mL) was used as the positive control and distilled water as the negative control. The results revealed that different parts of the plant exhibit different degrees of antibacterial activity. The ranking of the potency of antibacterial activity against Escherichia coli was whole plant > leaves > flowers > root > stem, while whole plant > flowers > roots > leaves > stem for Staphylococcus aureus. Phytochemical analysis revealed the presence of alkaloids, flavonoids, diterpenes and glycosides in certain parts of the plant while phenols, proteins and amino acids were found in all parts. The antibacterial activity is likely to be mediated by synergistic action via multiple mechanisms. A strong possibility exists to develop a safe and potent antibacterial agent from Heteropogon contortus.
Vishal Bharat Babar, Prajwala Rajkumar Khapale, Sudarshan Narayan Nagarale
International Journal of Pharmacognosy and Life Science, Volume 1, pp 51-54; https://doi.org/10.33545/27072827.2020.v1.i1a.18

Abstract:
Cancer cause sickness and consequently can be viably overwhelmed by a multi-constituently remedial strategy. Herbal extracts shows the example of such stratagem. However, less research have been carried out till date that portray the effect of different extraction techniques on the phyto compounds profile of plant extracts and its effect on anticancer activity. Momordica charantia is a member of the Cucurbitaceae. It is a popular vegetable harvest in Indian customary medicine since olden times. It has potential lipid lowering and antioxidant activity and antidiabetic. In the present study, we have evaluated the anticancer prospective of methanolic and acetone extracts of Momordica charantia (MCME) and (MCAE). Reported results show that (MCME) is rich in bioactive compounds shown anticancer activity with Cell lines of (IC50) with MCF 715.6 ± 1.3 and HeLa 28.2 ± 1. This study based on the presence of cytotoxic from the Momordica charantia, which have been further used in herbal formulations study as an anticancer activity. Our conclusion support additional indepth study of this pharmacologic activity as a malignant tumour agent.
Vishal Bharat Babar, Shivaraj Sopan Dhage, Amit Vilas Pondkule, Sudarshan Nagarale
International Journal of Pharmacognosy and Life Science, Volume 1, pp 44-46; https://doi.org/10.33545/27072827.2020.v1.i2a.19

Abstract:
In the present study was undertaken to evaluate the mucilage obtained from the calyx of flower of Hibiscus rosasinensis Linn as a suspending agent. A suspension of CaCO3 was prepared using 2 % w/v of hibiscus mucilage as suspending agent and it is evaluated for its stability using the parameters like, sedimentation volume, viscosity, redispersibility and pH. The suspending effect of hibiscus mucilage was compared with CaCO3 suspensions prepared using 2 % w/v of suspending agents such as acacia and tragacanth. The results obtained indicated that the hibiscus mucilage could be used as a suspending agent. It has low rate of sedimentation, high viscosity, slightly basic pH and is easily redispersible. These effects were comparable with that of the standard suspending agents like acacia and tragacanth. The mucilage isolated from the calyx of flower of Hibiscus rosasinensis can be used as a pharmaceutical adjuvant.
Ahmed Ali Mustafa, Reham Mohamed Basher, Nouf Faisal Ibrahim, Afaf R Taher, Haifa Abbas Awad
International Journal of Pharmacognosy and Life Science, Volume 1, pp 47-49; https://doi.org/10.33545/27072827.2020.v1.i2a.20

Abstract:
Phytochemical screening of the medicinal plants reveals, very important and vital phytochemicals like tanins, saponin, flavonoids, Terpenoids and/or Stroids, alkaloids and anthraquinones, at a very appreciable quantity. In this study aims to assess the phytochemicals screening for ethanolic extracts of Boscia senegalensis, Cymbopogom schoenanthus, Hydnora abysinica and Rhynchosia minima., from the Sudan. The results showed the phytochemical screening revealed the presence of tannins, saponins, flavonoids, terpenoids and/or stroids, alkaloids and anthraquinones, in all plants, expect tannins (Boscia senegalensis), saponins (Hydnora abysinica), flavonoids (Cymbopogom schoenanthus), terpenoids and/or Stroids (Boscia senegalensis and Rhynchosia minima.,) and alkaloids (Cymbopogom schoenanthus). However, we can see a phytochemical screening harvested in all plants ethanolic extracts highlighted in this study could justify the traditional uses of this plant in the treatment of several pathologies.
Yogesh T Sonawane, Sushil S Pmipare, Chetan A Chaudhari, Naveenkumar P Jain, Sc Pal, Chhaya H Gadgoli, Vinod A Bairagi, Sunita A Govilkar, Aher Bhaskar
International Journal of Pharmacognosy and Life Science, Volume 1, pp 06-13; https://doi.org/10.33545/27072827.2020.v1.i2a.11

Abstract:
Aim: Woodfordia fruticosa (Lythraceae) commonly called as ‘Dhatakipuspha’ in India. In Ayurveda, The fresh flower of W. fruticosa has been reported to stop bleeding in emergency cuts, while the dried flower powder to heal wounds more efficiently. Traditionally Woodfordia fruticosa Kurz is used in wound healing by tribes of Chhattisgarh, India. There was no scientific evidence justifying the use of Woodfordia fruticosa for treating wounds, therefore the present study was aimed at evaluation of wound healing activity of the plant. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Materials and Methods: In the present study the flowers of Woodfordia fruticosa were studied for wound healing activity by incorporating the methanolic and total aqueous extract in simple ointment base B.P. in concentrations of 1% (w/w) and 2% (w/w). Ointments were also prepared using yashad bhasma (1.25% w/w) (equivalent zinc concentration 0.95% w/w) and yashad bhasma (0.625% w/w) (equivalent zinc concentration 0.45% w/w and 0.56% w/w) in combination with methanolic and total aqueous extract (1% w/w) in simple ointment base B.P. Wound healing activity was studied in the wound models in rats viz. excision and incision. In case of the excision wound model, wound contraction, period of epithelization and hydroxyproline content in the scab were studied, while incision wound model was evaluated by determining tensile strength of the newly formed skin. Results: Treatment of wound with ointment containing 2% (w/w) the methanolic and total aqueous and yashad bhasma (0.625% w/w) in combination with the methanolic and total aqueous extract (1% w/w) exhibited significant (P
Deepanshi Tiwari, Mamta Tiwari
International Journal of Pharmacognosy and Life Science, Volume 1, pp 38-43; https://doi.org/10.33545/27072827.2020.v1.i2a.17

Abstract:
Vincristine is a chemotherapeutic agent that is a component of many combination regimens for a variety of malignancies, including several common pediatric tumors.78% of patients with advanced malignant disease were treated with vincristine, an alkaloid derived from vinca rosea Linn, 59% of these survived from the beginning of treatment and could be evaluated. Favourable responses were seen in patients with Hodking’s disease, reticulum cell sarcoma, lymphosarcoma, carcinoma of the breast, acute leukemia and choriocarcinoma. Toxic include a high incidence of alopecia and neurologic complications. Vincristine treatment is limited by a progressive sensorimotor peripheral neuropathy. Vincristine-induced peripheral neuropathy (VIPN) is particularly challenging to detect and monitor in pediatric patients, in whom the side effect can diminish long term quality of life. Further research is needed to predict, prevent, and treat disease to maximize therapeutic benefit and avoid unnecessary toxicity from vincristine treatment.
Olubunmi J Sharaibi, Rakesh Kumar Joshi, Olubunmi S, Omoteso K Oluwa
International Journal of Pharmacognosy and Life Science, Volume 1, pp 33-37; https://doi.org/10.33545/27072827.2020.v1.i2a.16

Abstract:
Curculigo pilosa (Schum. & Thonn) Engl. is a tropical African flowering plant belonging to the family Hypoxidaceae. It is a highly valued medicinal plant used in traditional medicine to treat constipation, impotence, limb limpness, arthritis, knee joints, and watery diarrhea. It is also used as a potent immunomodulator and aphrodisiac. The aim of this study is to evaluate the phytochemical constituents and free radical scavenging activity of the fresh and dried samples of C. pilosa. Fresh plant samples were purchased from herbal market at Iyana-Iba market in Ojo local government area. Some of the samples were oven dried at 30 oC to get the dried sample. Phytochemical analysis was carried out using standard laboratory procedures while ferric reducing power, nitric oxide and DPPH scavenging assays were used to evaluate the antioxidant activity of the samples. Both dried and fresh samples contained phenols, flavonoids, saponins, alkaloids and cardiac glycosides. Tannins was present in the extracts except the aqueous extract of the dried sample while terpenoids was present only in the acetone extract of the fresh and dried sample but absent in the aqueous extract of both samples. Fresh sample contained the highest amount of phytochemicals in both extracts. The amount of phenols in aqueous and acetone extracts of the fresh sample was 68.51 mg g-1 and 80.94 mg g-1 respectively. Fresh samples exhibited higher scavenging activity than the dried sample. Fresh sample of C. pilosa contained more phytochemicals and exhibited higher free radical scavenging activity than the dried sample.
Pankaj Singh, Mamta Tiwari
International Journal of Pharmacognosy and Life Science, Volume 2, pp 28-33; https://doi.org/10.33545/27072827.2021.v2.i1a.24

Abstract:
Neem has become important in the global context today because it offers answers to the major concerns facing mankind. Azadirachta indica is a fast growing evergreen popular tree found commonly in India, Africa and America. This review gives a bird’s eye view mainly on the biological activity and its preventive-promotive medicinal uses and applications over all this review also tell you that how the “neem is the one solution of thousand problems”, like Antiallergenic, antidermatic, antifeedent, antifungal, anti- inflammatory, antipyretic, antiscabic, cardiac, diuretic, insecticidal, parricidal, nematicidal, spermicidal and other biological activities.
Pratik R Wankhade, Rani D Gupta, Renuka J Das, Nishant B Awandekar, Milind J Umekar
International Journal of Pharmacognosy and Life Science, Volume 2, pp 34-43; https://doi.org/10.33545/27072827.2021.v2.i1a.25

Abstract:
Embelia ribes is a kind of Embelia. Burm. f. is a member of the Myrsinaceae family, which grows in hilly areas of India up to 1500 metres in elevation, from the outer Himalayas to the Western Ghats. Embelia ribes Burm. f. is a rare medicinal plant that has been studied extensively for its diverse medicinal characteristics. The use of medicinal plants in therapeutics is perhaps as old as recorded history. Embelia ribes is one of most significant medicinal plant. Nearly each part of this plant contains varied chemical constituents and is utilized within the treatment of various. Broad inquire about work has been detailed in last few decades on this important plant of Embelia ribes berries contain a few chemical constituents like embelin, volatile oil, fixed oil, resin, tannin, christembine, phenolic acids like caffeic acid, vanillic acid, chrorogenic acid, cinnamic acid, o-cumaric acid 4.33% of the embelin content is observed within the berries of Embelia ribes Burm F. It is a critically endangered medicinal plant known for its digestive, carminative, and laxative effects. Embelia ribes also has the following properties: Antihelminthic, antibacterial, antioxidant, anti-diabetic, anticonvulsant, anti-cancer, and antihyperlipidemic, Antifungal, Antihyperhomocysteinemic, Mollusicidal, Wound healing, Antifertility, Antihyperglycemic, Antitumor and anti-inflammatory, Chemotherapeutic, Contraceptive, Anxiolytic, Antidepressant, Antimitotic, Cardio protective effect, Antiobesity, and Antihyperlipidemic are all treated with it. Embelia ribes was studied for its hepatoprotective and analgesic properties.
Hamida AL Barasi, Samia Elzwi
International Journal of Pharmacognosy and Life Science, Volume 1, pp 29-32; https://doi.org/10.33545/27072827.2020.v1.i2a.15

Abstract:
Cinnamon may be a small evergreen tree 10-15 meters tall, belongs to the family Lauracae. The leaves are ovate-oblong in shape, 7-18 Cm long, the flowers which are arranged in panicles, have greenish color and distinct odor. The fruit may be a purple one centiberry containing one seed. Cinnamon are widely used as spice and flavoring agent and may be clinically utilized in treatment of certain diseases like type 2 DM. Cinnamon extract has blood sugar lowering effect in patients with type 2 diabetes. This study tested the effect of cinnamon extract on D- glucose induced hyperglycemias which showed significant reduction in plasma glucose level. Chronic hyperglycemia model induced by one intraperitoneal injection of streptozotocin, the extract showed marked decrease in blood sugar level.
Yash R Menghani, Dhanshree M Bhattad, Kamala K Chandak, Jayshree R Taksande, Millind J Umekar
International Journal of Pharmacognosy and Life Science, Volume 2, pp 18-27; https://doi.org/10.33545/27072827.2021.v2.i1a.23

Abstract:
Alzheimer’s disease (AD) is a progressive, neurodegenerative disorder and has become a great health problem particularly among the elderly people, generally occurs after the age of 55 years and increase in incidence with advancing age, affecting nearly 25 million people worldwide. Alzheimer’s disease (AD) was first identified by the German psychiatrist, Alois Alzheimer, in 1907. People with this disease may exhibit symptoms of short-term memory loss, diminished motor skills, inefficient coordination and impaired intellectual capabilities. The cause of AD is not exactly known, but is thought to include both genetic and environmental factors (multifactorial). There is no known cure for Alzheimer’s disease, since it is not possible to reverse the death of brain cells but the symptoms can be managed by some pharmacological agents and herbal remedies. The herbal remedies are becoming more popular in the recent years and providing very promising benefits to the patients suffering from AD. Several clinical trials using herbal mixtures are also going on and will hopefully show positive results for treating AD in the future. This paper reviews the Pathophysiology of AD along with the synthetic drugs and herbal medicines which are used for the Management of AD.
Rakesh Kumar Joshi, Rachid Soulimani
International Journal of Pharmacognosy and Life Science, Volume 1, pp 33-37; https://doi.org/10.33545/27072827.2020.v1.i1a.7

Abstract:
Ethano-medicinal and phytochemical potential of Carum carvi Linn. and Cuminum cyminum: A review
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