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(searched for: Complex Odontoma: A Case Report)
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A S Demiralp, E Erdem, A Oztürk
Published: 1 September 1988
Ankara Üniversitesi Diş Hekimliği Fakültesi Dergisi, Volume 15, pp 117-9

R Bertolai, , R Sacco, T Agostini
Published: 20 December 2007
Minerva Dental and Oral Science, Volume 56

Abstract:
The clinical presentation of Ludwig's angina consists in a severe expanding cellulitis causing swelling of the floor of the mouth, tongue and submandibular region, thus resulting in a possible obstruction of the airway and in a rapid progress in deep neck soft tissue infection and mediastinitis with potentially fatal consequences. Frequently, submandibular cellulitis develops from an acute infection spreading from the lower molar teeth. Mandibular fractures, traumatic laceration of the floor of the mouth, and peritonsillar abscesses are other concomitant clinical features. A case of Ludwig's angina associated with a large erupted odontoma and with a deeply impacted third molar displaced to the border of the mandible is described. The patient was affected by enlargement of submandibular space, marked face swelling causing an evident face deformity, tenderness and redness of the neck and limited movement of the neck and mouth. In the past, Ludwig's angina was frequently fatal, however aggressive surgical and medical therapy have significantly reduced the mortality rate. The reported case can be considered as important, not only because of the rarity of the odontoma eruption in the oral cavity, but mainly for the extent of the clinical manifestation of a lesion usually described in literature as asymptomatic.
S. Peters, N. Bhalla, T. Kunkle, J. Costandi, B. Ferguson, A. Yoon, E. Philipone
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 124; https://doi.org/10.1016/j.oooo.2017.06.032

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Daniel Vlcek, Peter A Reichart, Dieter D Bosshardt, Roberto Sleiter,
Schweizer Monatsschrift fur Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia, Volume 122

Abstract:
Odontomas are the most common odontogenic tumours. They are considered as hamartomas - a local tissue malformation without autonomous growth potential - and are non-neoplastic. Clinically and histopathologically, compound and complex odontomas can be differentiated. Compound odontomas consist of a varying number of tooth-like structures and histology show dental tissues in an orderly pattern. Most often compound odontomas are diagnosed in young patients in the anterior maxilla. Patients are rarely complaining of symptoms and they are usually diagnosed during routine radiographic examinations or due to late eruption of permanent or persistence of deciduous teeth. The following case report presents a disturbed eruption of a lateral right incisor of the maxilla in a 8-year old female patient. Clinical, radiological and histopathological characteristics of this lesion will be discussed as well as therapy and follow-up.
, Winarno Priyanto, Kiki A. Rizki, Andri Hardianto
Published: 1 December 2017
Journal of Dentomaxillofacial Science, Volume 2; https://doi.org/10.15562/jdmfs.v2i3.518

Abstract:
Objective:Odontomas are the most common form of odontogenic tumors of the jaw, represent a benign hamartoma rather than a true neoplasm. They constitute 22% of all odontogenic tumors. Odontomas are consist of two types, compound and complex. The compound odontomas contain recognizable enalmel, dentin and sometimes cementum, shaped in toothlike structures; whereas complex odontomas are composed of irregular masses of dentin and enamel and have no anatomic resemblance to a tooth. Methods: A17-year-old female patient came to Department of Oral and Maxillofacial Surgery with a slow growing and asymptomatic swelling in her left mandible. The panoramic radiograph showed a radioopacity and radiolucent lesion, with well-corticated limits. The radioopaque area was amorphous, circumscribed by a thin and irregular radiolucent halo. An inscisional biopsy confirmed the lesion as a complex odontoma. The surgery performed was hemimandibulectomy followed by a reconstruction using a plate under general anaesthesia. Results:Complex odontomas are most likely to be found in the posterior region of the maxilla or the mandible and can be treated with a simple enucleation and curettage. In this case report the hemimandibulectomy was performed due to the extensiveness of the mass. Conclusion:Surgical removal of large complex odontoma with hemimandibulectomy is a rare clinical scenario. The extensiveness of the lesion contributed to its removal technique.
Madhusudhan Reddy, A Jacob Prakash Rao, Vijaya Lakshmi Mahanthi, K Venkata Chalapathi
Published: 1 January 2019
Journal of cancer research and therapeutics, Volume 15, pp 715-718; https://doi.org/10.4103/jcrt.jcrt_215_17

Abstract:
Ameloblastic fibro-odontoma (AFO) is a benign, epithelial odontogenic tumor with odontogenic mesenchyme having the histologic characteristics of both ameloblastic fibroma and complex odontoma. This report describes the case of a 14-year-old girl with AFO on the right posterior mandibular region that mimics complex odontoma on incisional biopsy due to the presence of atypical dentin- and cementum-like areas. On histological examination, sections of excisional biopsy showed odontogenic epithelial islands with embryonic connective tissue and decalcified sections showed atypical dentin with dentinal tubules and islands of cementum. These features led to the diagnosis of AFO.
L. Chandra Shekar, A. Steffina Lydia Jascinth, G. Sathees Chandra Mouli, A. Feroz Khan
British Journal of Medicine and Medical Research, Volume 17, pp 1-5; https://doi.org/10.9734/bjmmr/2016/27815

Abstract:
Odontomas are the most common type of benign odontogenic tumours; they are asymptomatic and are often discovered during routine radiographs of the jaws. Odontomes can be used as stem cell reservoirs and generally eruption of an odontome into the oral cavity and occurrence of a complex odontome in the anterior maxilla is rare. We report two cases of odontomes one a rare case of erupting complex odontome in the anterior maxilla and the other rare case of partially erupted odontome.
, A. Mohamed, A. Singh, C. E. E. Noffke
Published: 4 February 2011
Journal of Maxillofacial and Oral Surgery, Volume 12, pp 480-484; https://doi.org/10.1007/s12663-010-0148-y

Abstract:
Odontomas are the most common benign tumours of odontogenic origin. Due to their hamartomatous nature, they are usually asymptomatic but can cause impaction of one or more teeth. They consist microscopically of all the tissue types found in a developed tooth. We present a case of a large sequestrating complex odontoma resulting in facial asymmetry, cellulitis, pain and partial loss of function. This case has significance, as odontomas of this large size have rarely been reported.
A S Nogueira, E S Gonçales, A G B Gonçales, V Thiegui-Neto, C B P Nogueira, R Medeiros
Published: 1 September 2013
Minerva Dental and Oral Science, Volume 62

Abstract:
Odontomas represent the most prevalent odontogenic tumors in the jaw. The treatment of choice is surgical removal, usually performed by conventional techniques involving ostectomies to expose the tumor. In this paper, the authors describe, through the report of a case of complex odontoma located in the mandibular angle, a more conservative surgical technique called corticotomy, in which the bone removed for access to the tumor (buccal cortical) is repositioned and fixed by titanium plates of 1.5 mm.
Santosh R Patil, Krishna A Rao,
International Journal of Human and Health Sciences (IJHHS), Volume 1, pp 45-47; https://doi.org/10.31344/ijhhs.v1i1.8

Abstract:
Odontomas are the most common odontogenic tumors of the jaw bones which are benign, slow growing and asymptomatic. They are usually diagnosed on routine radiological examination during second decade of life. We report a rare case of bilateral compound odontomas in a geriatric patient.International Journal of Human and Health Sciences Vol. 01 No. 01 January’17. Page : 45-47
M O Ogunlewe, , A L Ladeinde, B O Bamgbose, O F Ajayi
Published: 1 December 2005
Nigerian Postgraduate Medical Journal, Volume 12, pp 312-5

Abstract:
Large complex odontomas of the jaws are rare. A report of a large complex odontoma of the mandibular angle-ramus region enucleated through intra-oral buccal approach is presented. A review of the literature on different modalities of treatment is also undertaken. A large expansile complex odontoma of the angle-ramus region of the mandible was excised through an intraoral buccal approach under general anaesthesia. Recovery and immediate post-operative period were uneventful. There was no altered sensation in the distribution of the inferior alveolar nerve and lingual nerve; and wound healing was satisfactory. Post-operative radiograph 2 years after the operation showed satisfactory bone regeneration. Intraoral buccal approach to large complex odontomas of the angle-ramus region of the mandible is a relatively safe procedure with minimal complication.
Published: 1 February 2015
Saudi medical journal, Volume 36, pp 228-232; https://doi.org/10.15537/smj.2015.2.9385

Abstract:
Odontomas are odontogenic tumors formed of various dental tissues. They are classified into: central odontomas that are common, eruption odontomas that are rare with only 23 cases reported to date, and peripheral odontomas that are also rare. We present a case of a large complex eruption odontome in a 24-year-old Saudi male. Saudi Med J 2015; Vol. 36 (2): 228-232http://doi.dx.org/10.15537/smj.2015.2.9385
, Sunita A. Managutti, Sangeeta P. Wanjari, Rajkumar N. Parwani
Published: 1 January 2011
Contemporary clinical dentistry, Volume 2, pp 215-7; https://doi.org/10.4103/0976-237X.86465

Abstract:
Odontomas are considered to be hamartomatous malformations rather than true neoplasms. This most common odontogenic lesion results from the growth of completely differentiated epithelial and mesenchymal cells that give rise to ameloblasts and odontoblasts. Dentigerous cyst is an epithelium-lined sac enclosing the crown of an unerupted tooth. Apparently, the dentigerous cyst arises by the accumulation of fluid between reduced enamel epithelium and the tooth crown. Occasionally it is associated with supernumerary tooth or odontoma. We report a case of dentigerous cyst associated with complex composite odontoma and an impacted lateral incisor in a 30-year-old male patient.
Piyali Adhikari, Rudra Prasad Chatterjee, Swagata Gayen, Mousumi Paul, Mehebuba Sultana, Sk. A. Mahmud, Sanjeet Kumar Das
European Journal of Dental and Oral Health, Volume 2, pp 1-4; https://doi.org/10.24018/ejdent.2021.2.2.43

Abstract:
Odontoma, a mixed odontogenic tumor, is considered to be a hamartoma rather than a true neoplasm. Fully developed odontomas chiefly consist of enamel, dentin, pulp and occasionally cementum. They are subdivided into compound and complex types. The compound odontoma is composed of multiple, small tooth like structures, whereas the complex type consists of a conglomerated mass of enamel and dentin, having no anatomical resemblance to a tooth. They are usually asymptomatic, slow growing but cause bony expansion, which is often discovered during routine radiography. Here, we report a case of a complex odontoma in the posterior left mandibular region in an eight year old female child.
, A. Jay, P. Ayliffe
Published: 11 March 2016
Journal: Oral Surgery
Oral Surgery, Volume 10, pp 40-42; https://doi.org/10.1111/ors.12210

The publisher has not yet granted permission to display this abstract.
R C Curreri, E J Messer, A L Abramson
Journal of oral surgery (American Dental Association : 1965), Volume 33, pp 45-8

Abstract:
During a screening examination for orthodontic evaluation and for possible partial anodontia, a large radiopaque mass was found in the right maxillary sinus of a 12-year-old boy. Further radiographic views were used to locate and establish a working diagnosis. The mass was removed with use of a standard Caldwell-Luc approach. It was diagnosed histologically as a complex odontoma.
Luis A Litonjua, , Lucia S Valderrama, Mirdza E Neiders
Published: 23 June 2004
General dentistry, Volume 52

Abstract:
A case involving a 17-year-old girl with a large erupted odontoma associated with a deeply impacted mandibular molar is reported. The molar, which previously had been displaced to the border of the mandible, erupted successfully three years after surgical removal of the odontoma. A review of the literature presents guidelines for treating similar cases.
C Gervasoni, A Tronchet, S Spotti, S Valsecchi, V Palazzolo, S Riccio, A D Aiuto, L Azzi, A Di Francesco
Journal of Biological Regulators and Homeostatic Agents, Volume 31, pp 119-125

Abstract:
Odontomas are one of the most common Odontogenic Tumors of the jaw. The exact etiology of odontomas is unknown. Histologically they are composed of various formations of dental tissue (enamel, dentin, cementum and sometimes pulp). In the WHO classification, they are divided into complex odontoma and compound odontoma. Clinically, odontomas are generally asymptomatic and only in rare cases cause swelling, pain, suppuration or bony expansion. Radiologically, the tumor is initially lucent, but with time, it develops small calcifications, which eventually coalesce to form a radiodense lesion with a lucent rim. Surgical resection is the treatment of choice and there is no recurrence. The aim of this paper is to define the principal characteristics and the treatment of these lesions, based on literature and personal experience.
L. A. N. Santos, L. J. Lopes, , V. F. Oliveira,
Published: 17 May 2016
Case Reports in Dentistry, Volume 2016, pp 1-6; https://doi.org/10.1155/2016/3584751

Abstract:
Odontomas are the most common benign tumors of odontogenic origin. They are normally diagnosed on routine radiographs, due to the absence of symptoms. Histopathologic evaluation confirms the diagnosis especially in cases of complex odontoma, which may be confused during radiographic examination with an osteoma or other highly calcified bone lesions. The micro-CT is a new technology that enables three-dimensional analysis with better spatial resolution compared with cone beam computed tomography. Another great advantage of this technology is that the sample does not need special preparation or destruction in the sectioned area as in histopathologic evaluation. An odontoma with CBCT and microtomography images is presented in a 26-year-old man. It was first observed on panoramic radiographs and then by CBCT. The lesion and the impacted third molar were surgically excised using a modified Neumann approach. After removal, it was evaluated by histopathology and microtomography to confirm the diagnostic hypothesis. According to the results, micro-CT enabled the assessment of the sample similar to histopathology, without destruction of the sample. With further development, micro-CT could be a powerful diagnostic tool in future research.
, Sandra C Barbosa, Marcelo Marcucci, Jefferson X Oliveira, Cesar A Lascala, Rodrigo C Mosca
Published: 1 January 2009
Indian Journal of Dental Research, Volume 20, pp 230-4; https://doi.org/10.4103/0970-9290.52890

Abstract:
Odontoameloblastoma (OA) is a very rare mixed odontogenic neoplasm, characterized by the simultaneous occurrence of an ameloblastoma and a compound or complex odontoma in the same tumor mass. To date, less than 50 cases of OA and/or ameloblastic odontoma have been reported in the English dental literature. This neoplasm was called ameloblastic odontoma. The term OA was included in the 1971 WHO classification. In this study, we present two cases of OA, which we hope will contribute to the awareness and knowledge of surgeons regarding the existence of this odontogenic tumor so that patients having it may be treated and followed-up properly.
, , Bilge Can Meydan
Published: 1 January 2012
Journal: Dentistry
Abstract:
Odontoameloblastoma (OA) is an extremely rare mixed odontogenic tumor with odontogenic mesenchyme displaying the histologic characteristics of ameloblastic fibroma and complex odontoma. OA occurs predominantly in children and young adults. The majority of the tumours are associated with unerupted teeth. OA is generally asymptomatic and occurs in either jaws with slight inclination for mandible. Review of the literature exhibits only four reported cases in the posterior maxilla. This report presents an OA in the posterior region of the maxilla of an 11-yearold female. The lesion was surgically treated, no recurrence has been observed on follow-up.
T. Y. Kobayashi, C. V. Gurgel, , D. Rios, M. A. A. Machado,
Published: 30 April 2013
European Archives of Paediatric Dentistry, Volume 14, pp 185-189; https://doi.org/10.1007/s40368-013-0036-5

Abstract:
Background Odontomas are odontogenic tumours, resulting from epithelial growth and differentiated mesenchymal cells, clinically asymptomatic, and often associated with changes to the eruption of the permanent dentition. In recent years, cone beam computed tomography (CBCT) has been used in the diagnosis and treatment planning of this condition. Case report A 9-year-old male patient, with an unerupted permanent maxillary right central incisor (tooth 11) presented to our clinic. The panoramic radiograph showed impaction of tooth 11 with incomplete root development and the suspicion of an odontome and supernumerary tooth. CBCT was performed and enabled the visualisation of a radiopaque image compatible with an odontome, confirming the presence of an impacted supernumerary tooth on the palatal surface of tooth 11. Treatment Surgical excision of the odontome and the supernumerary tooth was performed. Follow-up Clinical and radiographic evaluations 2 months after the removal of the lesion showed lack of space for the eruption of tooth 11. The patient was referred for orthodontic treatment and a Hyrax appliance was fitted. The patient has been followed for 12 months. Conclusion CBCT is an important auxiliary tool, aiding in both correct diagnosis and accurate treatment planning. It is currently a technology accessible to most paediatric dentists and should be beneficial considering the diagnostic information provided as well as the cost-benefit ratio for the patient.
, , Nirmala N. Rao, K. M. Cariappa
Published: 24 December 2015
Journal of Maxillofacial and Oral Surgery, Volume 15, pp 320-324; https://doi.org/10.1007/s12663-015-0859-1

Abstract:
Odontomas are the most common odontogenic tumors of the oral cavity which are nonaggressive, hamartomatous in nature consisting of enamel, dentin and cementum. They are called as composite because they contain more than one type of tissue. They are generally asymptomatic, hence recognised on routine radiologic examination. The compound odontoma is composed of multiple small tooth like structures, whereas the complex odontoma consists of a conglomerate mass of enamel and dentine, which bears no anatomical similarity to the tooth. The eruption and infection of odontoma are uncommon, only few cases of erupted complex odontoma are reported in the literature. We report a case of silent erupting complex odontoma.
B M Owens, N J Schuman, T A Pliske, W L Culley
Published: 1 January 1995
Journal of Clinical Pediatric Dentistry, Volume 19, pp 293-5

Abstract:
This case report involved the removal of a compound composite odontoma from a fourteen year-old male patient at an urban dental school. The pathology report did indeed reveal the tissue mass was that of a compound composite odontoma. These lesions usually occur in the second decade of life, in the anterior maxilla or mandible, with no gender or race predilection. Three types of odontomas are identified, including are: compound composite odontoma, complex composite odontoma, and ameloblastic fibro-odontoma. The etiology of these lesions is unknown, although environmental (trauma, infection) and hereditary influences play a role. Treatment consists of complete enucleation and curettage followed by histological verification by an oral pathologist.
H. Nouri, A. Raji, B. Ait M'barek
Revue de Stomatologie et de Chirurgie Maxillo-faciale, Volume 108, pp 455-457; https://doi.org/10.1016/j.stomax.2007.04.003

Abstract:
Ameloblastic fibro-odontoma, ameloblastic fibroma, and odontoma are rare malformations, which are classified as odontologic tumors. They usually progress in an asymptomatic way, and making the histological distinction between these variants is very difficult. We report the case of a 14-year-old girl presenting with an ameloblastic fibro-odontoma of the maxillary sinus. The clinical signs were nasal obstruction and jugular tumefaction. Surgical excision was performed through a paralateronasal approach. The diagnosis of fibro-odontoma was confirmed by the histopathological analysis of the surgical piece. Odontologic tumors form a complex entity, the histological nature and the correlations of which are discussed.
V Singaravel, , K Raja, R Vijayakumar, S Asrafuzzaman
Diseases of aquatic organisms, Volume 125, pp 115-124; https://doi.org/10.3354/dao03141

Abstract:
We report the spontaneous occurrence of oral neoplasms in pickhandle barracuda Sphyraena jello Cuvier, 1829 from Parangipettai, on the southeast coast of India. A total of 11736 fish were examined, of which 43 were affected with oral tumours, with an overall prevalence of 0.37%. Gross and clinical symptoms included reddish to grayish-white distended tumourous growths on the gingiva, intra-oral bones and tongue. The tumours exhibited delayed eruption and intra- or extra-oral swelling, varied in consistency from extremely firm to fleshy and released mucinous material. The majority of tumours consisted of numerous clumped toothlets, but some included hardened tissues. Local area invasion/transmission was observed in most cases; however, necropsy examination revealed no gross evidence of distant metastasis into visceral organs. Radiographic examination of compound odontomas revealed distinct unilocular radio-opaque mini-toothlets surrounded by defined radiolucency, whereas complex odontomas exhibited unilocular and indistinct radio-opaque masses within a much more extensive radiolucent zone. Histopathologically, the intra-oral tumour lesions were characterized by numerous imperfect (germ) toothlets consisting of a disorganized combination of dental tissues: pulp tissues with manifested and predominantly mixed hard dental tissues of immature dentine and enamel, numerous small to large and round to polyhedral ossicles embedded in hypocellular fibrous stromal tissues and sparsely spaced bland spindloid cells with cleft-like spaces of loose mucoid stroma. Histochemically, the neoplastic lesions stained positive for periodic acid-Schiff and Masson's trichrome. Based on the clinical and histological findings, the tumours were diagnosed as compound odontomas, complex odontomas, odontogenic myxomas, lingual myxomas and psammomatoid ossifying fibromas.
Correction
, A. Mohamed, A. Singh, C. E. E. Noffke
Journal of Maxillofacial and Oral Surgery, Volume 10, pp 344-348; https://doi.org/10.1007/s12663-011-0235-8

Abstract:
Odontomas are the most common benign tumours of odontogenic origin. Due to their hamartomatous nature, they are usually asymptomatic but can cause impaction of one or more teeth. They consist microscopically of all the tissue types found in a developed tooth. We present a case of a large sequestrating complex odontoma resulting in facial asymmetry, cellulitis, pain and partial loss of function. This case has significance, as odontomas of this large size have rarely been reported.
F. M. Poulet, B. A. Valentine, B. A. Summers
Published: 1 September 1992
Veterinary Pathology, Volume 29, pp 369-380; https://doi.org/10.1177/030098589202900501

Abstract:
A retrospective histologic study of 12 canine and eight feline epithelial odontogenic tumors and cysts was conducted from oral masses ( n = 3,917) obtained between 1980 and 1990. No sex or breed predilection was identified. Ameloblastoma was observed in two dogs (case Nos. 1, 2) 6 and 8 months of age. Calcifying epithelial odontogenic tumors were seen in a dog (case No. 3) and in two cats (case Nos. 4, 5) between 8 and 16 years of age. Ameloblastic fibroma (or fibroameloblastoma) was observed in cats (case Nos. 6–10) only. Inductive fibroameloblastoma was observed in four cats (case Nos. 6–9) up to 1 year of age, whereas ameloblastic fibroma was seen in a 14-year-old cat (case No. 10). A single ameloblastic odontoma was identified in a 20-month-old dog (case No. 11). Two complex odontomas occurred in a 6-month-old (case No. 12) and a 4-year-old (case No. 13) dog. Odontogenic cysts were identified in five dogs (case Nos. 14–18) aged 4.5 months to 16 years and in a 1-year-old cat (case No. 19) and have not been previously reported in these species. These cysts were lined by a stratified epithelium reminiscent of the appearance of ameloblastic epithelium. An odontogenic keratocyst with prominent central parakeratotic keratinization was identified in one 9-year-old female dog (case No. 20). Almost all epithelial odontogenic tumors were circumscribed, benign tumors that warranted a good prognosis for survival, although local recurrence may have followed (or may follow) incomplete excision. Calcifying epithelial odontogenic tumors may be locally invasive. Of six odontogenic cysts (case Nos. 14–19), two (case Nos. 15, 18) gave rise to basi-squamous carcinomas. The classification and behavior of epithelial odontogenic tumors and cysts in human beings, dogs, and cats are discussed.
Aakarsh V. Jhamb, Rameshwar Dolas, Prashant Pandilwar, Parul A. Jhamb,
Open Journal of Stomatology, Volume 02, pp 44-49; https://doi.org/10.4236/ojst.2012.21008

Abstract:
Odontoma is a hamartomatous lesion of odontogenic origin involving both epithelial and mesenchymal tissues. Although it is not an uncommon lesion yet in certain conditions it can lead to complications if left untreated. This is a retrospective review of 30 diagnosed odontoma cases from the archives of Department of Oral & Maxillofacial Surgery, Government Dental College & Hospital, Nagpur, India. Out of these 30 cases, 17 were diagnosed as complex odon toma and 13 cases as compound odontoma. Two of these unusual cases have been described which emphasize the importance of early & appropriate treatment to prevent further morbidity
P. Galvez, E. Garot, A. Bres, A. Crelier, C. Castain, S. Catros, M. Fenelon
Published: 10 February 2021
Journal of Oral Medicine and Oral Surgery, Volume 27; https://doi.org/10.1051/mbcb/2020067

Abstract:
Introduction: Dilated odontoma is the most severe form of a dens invaginatus, which is a rare dental malformation resulting from an invagination of the enamel organ into the dental papilla before calcification occurs. Observation: A healthy 7-years-old girl was referred to the oral surgery department to remove an impacted odontoma causing a delayed dental eruption of the right mandibular lateral incisor (tooth 42). The patient was painless and a lingual osseous swelling was observed. A computed tomography and a 3D segmentation revealed a shell-shaped mass in the position of the right mandibular lateral incisor, showing a complex anatomy. Surgical excision was carried out under general anesthesia. Histological analysis confirmed the diagnosis of DO. Discussion and conclusion: We performed a literature review investigating 16 cases of severe forms of dens invaginatus which required extraction. It highlighted the atypical aspect of our case and the importance of 3D imaging and segmentation in contributing to the accurate diagnosis and treatment of this dental malformation.
A G Hainline-Raez, D S Richardson
Published: 1 March 1985
ASDC journal of dentistry for children, Volume 52, pp 130-3

Abstract:
All that can be concluded from the available information is that the lesion was a variation on the spectrum of developmental anomalies without a known etiology or a conclusive diagnosis. This lesion is most probably related to an aborted formation of a maxillary first premolar or immature complex odontoma. More information could have been obtained, if the surgery had been delayed until further development of the lesion and of the patient's dentition had occurred; but this was not feasible, since definitive treatment was required. Further radiographic and clinical follow-up may assist in confirming the suspicion of a displaced maxillary left first premolar, when the patient's dentition is further developed. Since the position of the impacted primary tooth had not changed by the first follow-up examination, it is anticipated that it will not erupt on its own and will require further treatment, possibly in the form of surgical exposure and orthodontic manipulation or surgical removal and space management.
Journal of endodontics, Volume 26, pp 760-763; https://doi.org/10.1097/00004770-200012000-00026

Abstract:
Primary intraosseous salivary gland tumors are rare, with mucopidermoid carcinoma being the most frequent histotype. The authors present a case of adenoid cystic carcinoma, located in the mandibular incisor region, associated with pain. Endodontic treatment resulted in increased pain and progressive mandibular expansion. An apicoectomy was conducted, and an intraosseous adenoid cystic carcinoma was diagnosed at histological examination. The patient was treated by wide surgical resection, and is alive and well without recurrences or distant metastases 14 yr after the original diagnosis. The case presented herein calls attention to the preoperative clinical diagnosis of periapical lesions. Radiologically, focal sclerosing osteitis, cementoblastoma, cementifying and ossifying fibroma, periapical cemental dysplasia, complex odontoma, and calcifying epithelial odontogenic tumor should be considered in the differential diagnosis. In addition the unusual occurrence of salivary gland tumors in intraosseous location stresses the importance of systematic histological examination of any tissue sample obtained after endodontic procedures.
, A.Y. Gokbuget, S. Cintan, F. Seymen
International Journal of Oral & Maxillofacial Surgery, Volume 41, pp 42-45; https://doi.org/10.1016/j.ijom.2011.09.018

Abstract:
Ekman-Westborg and Julin is a trait that shows multiple macrodontia and multituberculism affecting only the teeth with no other anomalies (E-WJ). The aim of this report is to present a case which appears to manifest all the clinical signs of the E-WJ trait including odontoma formation. A 18-year-old girl with gingival inflammation particularly in the maxillary insicor area was referred to the authors' department. Panoramic, periapical and cephalometric radiographs were examined and complex odontoma associated with unerupted maxillary permanent lateral incisors was revealed. Intraoral examination revealed anterior crossbite, Angle Class III type malocclusion with mandibulary prominence and macrodontia of teeth 37, 12, 11 and 21. The patient was accepted as a new sporadic case of E-WJ. More case reports are needed to elucidate the causes and pathogenesis of this condition.
, Ha-Na Park, Kyoung-A Kim
Imaging Science in Dentistry, Volume 46, pp 267-272; https://doi.org/10.5624/isd.2016.46.4.267

Abstract:
Gardner syndrome is known as a variant of familial adenomatous polyposis. This syndrome is characterized by multiple intestinal polyposes, osteomas, and epidermoid cysts. In addition, dental abnormalities include an increased frequency of multiple odontomas, as well as supernumerary and impacted teeth. The authors report the case of a 7-year-old male patient with Gardner syndrome. Radiographic findings revealed multiple osteomas in both sides of the maxilla, multiple diffuse enostoses in both jaws, and a complex odontoma in the left mandibular body. Two years later, multiple epidermoid cysts on the scalp were found. Since this patient was suspected to have Gardner syndrome, the authors recommended gastrointestinal endoscopy to check for intestinal polyposis. Gastrointestinal endoscopic examination revealed multiple polyposes in the upper gastrointestinal tract and fundus of the stomach. As a result, the final diagnosis was Gardner syndrome.
H.P Philipsen,
Published: 20 December 1999
Journal: Oral Oncology
Oral Oncology, Volume 36, pp 17-26; https://doi.org/10.1016/s1368-8375(99)00061-5

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