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(searched for: 10.29328/journal.jcn.1001084)
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Kaur Kulvinder Kochar, Allahbadia Gautam, Singh Mandeep
Journal of Clinical Nephrology, Volume 6, pp 001-018; https://doi.org/10.29328/journal.jcn.1001084

Abstract:
The commonest etiology of acute kidney injury (AKI) is Sepsis that results in an escalation of morbidity and mortality in the hospital intensive care units. Existentially, the therapy of septic AKI rather than being definitive or curative is just supportive, without tackling the pathophysiology. Usually, Sepsis gets correlated with systemic inflammation, along with the escalated generation of Reactive oxygen species (ROS), in particular superoxide. Simultaneously liberation of nitric oxide (NO) subsequently reacts with the superoxide, thus, resulting in the generation of reactive nitrogen species (RNS), that is mostly peroxynitrite. This sepsis stimulated generation of ROS in addition to RNS might cause a reduction in the bioavailability of NO that modulates microcirculation aberrations, localized tissue hypoxia as well as mitochondrial impairment, thus starting a vicious cycle of cellular damage which results in AKI. Here we conducted a systematic review utilizing search engine PubMed, Google scholar; Web of science; Embase; Cochrane review library utilizing the MeSH terms like septic AKI; ROS; inducible nitric oxide synthase (iNOS); nicotinamide adenine nucleotide phosphate(NADPH)oxidase complex; Oxidative stress; Renal medullary hypoxia; Hypoxia inducible factor1; hypoxia responsive enhancer A; mitochondrial impairment; Intrarenal oxygenation; urinary oxygenation; erythropoietin gene; RRT; NAC; Vitamin C from 1950 to 2021 till date. We found a total of 6500 articles out of which we selected 110 articles for this review. No meta-analysis was done. Thus here we detail the different sources of ROS, at the time of sepsis, besides their pathophysiological crosstalk with the immune system, microcirculation as well as mitochondria that can result in the generation of AKI. Furthermore, we detail the therapeutic utility of N-acetylcysteine (NAC), besides the reasons for its success in ovine as well as porcine models of AKI. Moreover, we discuss preclinical along with clinical for evaluation of Vitamin C’s antioxidant effects as well as pleiotropic effects as a stress hormone that might aid in abrogation of septic AKI.
Published: 17 October 2020
Journal: Reactions Weekly
Reactions Weekly, Volume 1826, pp 279-279; https://doi.org/10.1007/s40278-020-84726-6

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Published: 1 November 2003
Journal of Child Neurology, Volume 18, pp 795-797; https://doi.org/10.1177/08830738030180111201

Abstract:
The Journal of Child Neurology (JCN) began in 1986 as a quarterly publication focused on child neurology and the related clinical pediatric neuroscience areas of pediatric neurosurgery, child psychiatry, pediatric neuroradiology, and developmental and behavioral pediatrics. As submitted material increased, JCN expanded in publication frequency and now appears monthly. Article quality has always been high and many articles have been frequently cited. Over the years, the ratings produced for the ISI Journal Citation Reports® have identified JCN as a high-ranking pediatric journal based upon the impact factor value. Currently (year 2002 figures), JCN (with its impact factor of 1.338) ranks 24th out of 68 pediatric journals. (J Child Neurol 2003;18:795—797).
Journal of Communications and Networks, Volume 6, pp 1-1; https://doi.org/10.1109/jcn.2004.6596845

Abstract:
This form is provided for original papers submitted to JCN and must be received by the JCN office before the paper is accepted for publication in JCN.
Journal of Communications and Networks, Volume 6; https://doi.org/10.1109/jcn.2004.6596649

Abstract:
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Journal of Communications and Networks, Volume 6; https://doi.org/10.1109/jcn.2004.6596648

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Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 5; https://doi.org/10.1109/jcn.2003.6596627

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Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 3, pp 1-1; https://doi.org/10.1109/jcn.2001.6596866

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This form is provided for original papers submitted to JCN and must be received by the JCN office before the paper is accepted for publication in JCN.
Journal of Communications and Networks, Volume 1, pp 1-1; https://doi.org/10.1109/jcn.1999.6597015

Abstract:
This form is provided for original papers submitted to JCN and must be received by the JCN office before the paper is accepted for publication in JCN.
Journal of Communications and Networks, Volume 5; https://doi.org/10.1109/jcn.2003.6596829

Abstract:
Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 4, pp 1-1; https://doi.org/10.1109/jcn.2002.6596922

Abstract:
This form is provided for original papers submitted to JCN and must be received by the JCN office before the paper is accepted for publication in JCN.
Journal of Communications and Networks, Volume 3; https://doi.org/10.1109/jcn.2001.6596979

Abstract:
Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 3, pp 1-1; https://doi.org/10.1109/jcn.2001.6596805

Abstract:
This form is provided for original papers submitted to JCN and must be received by the JCN office before the paper is accepted for publication in JCN.
Journal of Communications and Networks, Volume 2; https://doi.org/10.1109/jcn.2000.6596608

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Journal of Communications and Networks, Volume 1; https://doi.org/10.1109/jcn.1999.6596762

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Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 1; https://doi.org/10.1109/jcn.1999.6596704

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Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 22, pp 162-168; https://doi.org/10.1109/jcn.2020.100012

Abstract:
Journal of Communications and Networks (JCN) was launched in March 1999. It is published six times per year, and is committed to publishing high quality papers that advance the state-of-the-art and practical applications of communications and information networks. Theoretical research contributions presenting new techniques, concepts, or analyses, applied contributions reporting on experiences and experiments, and tutorial expositions of permanent reference value are welcome. The subjects covered by this journal include all topics in communication theory and techniques, communication systems, and information networks. JCN is indexed in Science Citation Index Expanded (SCIE), Engineering Village and Scopus. The official title is Journal of Communications and Networks (JCN) and the abbreviate title is ‘J.Commn.Net’.
Journal of Communications and Networks, Volume 10; https://doi.org/10.1109/jcn.2008.6389870

Abstract:
Provides instructions and guidelines to prospective authors who wish to submit manuscripts.
Journal of Communications and Networks, Volume 7; https://doi.org/10.1109/jcn.2005.6387765

Abstract:
Provides instructions and guidelines to prospective authors who wish to submit manuscripts.
Journal of Communications and Networks, Volume 15, pp 1-1; https://doi.org/10.1109/jcn.2013.000018

Abstract:
Advertisement: Journal of Communications and Networks (JCN) - a publication of the Korean Institute of Communications and Information Sciences (KICS). JCN subscription application / renewal form.
Journal of Communications and Networks, Volume 15, pp 1-1; https://doi.org/10.1109/jcn.2013.000059

Abstract:
Provides tyhe latest subscription application/renewal form for the JOURNAL OF COMMUNICATIONS AND NETWORKS (JCN), a Publication of the Korean Institute of Communications and Information Sciences (KICS)
Journal of Communications and Networks, Volume 12; https://doi.org/10.1109/jcn.2010.6388461

Abstract:
Provides instructions and guidelines to prospective authors who wish to submit manuscripts.
Journal of Communications and Networks, Volume 10; https://doi.org/10.1109/jcn.2008.6388339

Abstract:
Provides instructions and guidelines to prospective authors who wish to submit manuscripts.
Journal of Communications and Networks, Volume 6; https://doi.org/10.1109/jcn.2004.6596850

Abstract:
Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 6; https://doi.org/10.1109/jcn.2004.6596849

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Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 5; https://doi.org/10.1109/jcn.2003.6596689

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Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 5; https://doi.org/10.1109/jcn.2003.6596628

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Journal of Communications and Networks, Volume 4; https://doi.org/10.1109/jcn.2002.6596906

Abstract:
Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 4, pp 1-1; https://doi.org/10.1109/jcn.2002.6596903

Abstract:
This form is provided for original papers submitted to JCN and must be received by the JCN office before the paper is accepted for publication in JCN.
Journal of Communications and Networks, Volume 2; https://doi.org/10.1109/jcn.2000.6596729

Abstract:
Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 2; https://doi.org/10.1109/jcn.2000.6596728

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Journal of Communications and Networks, Volume 1; https://doi.org/10.1109/jcn.1999.6597019

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Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 1, pp 1-3; https://doi.org/10.1109/jcn.1999.6597018

Abstract:
This index covers all papers that appeared in JCN during 1999. The Author Index contains the primary entry for each item, listed under the first author's name, and cross-references from all coauthors. The Title Index contains paper titles for each Division in the alphabetical order from No. 1 to No. 4. Please refer to the primary entry in the Author Index for the exact title, coauthors, and comments / corrections.
Journal of Communications and Networks, Volume 6; https://doi.org/10.1109/jcn.2004.6596999

Abstract:
Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 6; https://doi.org/10.1109/jcn.2004.6596592

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Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 4; https://doi.org/10.1109/jcn.2002.6596925

Abstract:
Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 4, pp 1-1; https://doi.org/10.1109/jcn.2002.6596665

Abstract:
This form is provided for original papers submitted to JCN and must be received by the JCN office before the paper is accepted for publication in JCN.
Journal of Communications and Networks, Volume 3; https://doi.org/10.1109/jcn.2001.6596889

Abstract:
Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 3; https://doi.org/10.1109/jcn.2001.6596809

Abstract:
Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 2, pp 1-1; https://doi.org/10.1109/jcn.2000.6596781

Abstract:
This form is provided for original papers submitted to JCN and must be received by the JCN office before the paper is accepted for publication in JCN.
Journal of Communications and Networks, Volume 2; https://doi.org/10.1109/jcn.2000.6596748

Abstract:
Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 2; https://doi.org/10.1109/jcn.2000.6596747

Abstract:
Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 1; https://doi.org/10.1109/jcn.1999.6596958

Abstract:
Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 1; https://doi.org/10.1109/jcn.1999.6596957

Abstract:
Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 1; https://doi.org/10.1109/jcn.1999.6596761

Abstract:
Presents the back inside cover of this issue of the periodical.
Journal of Communications and Networks, Volume 1; https://doi.org/10.1109/jcn.1999.6596705

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Journal of Communications and Networks, Volume 20, pp 1-1; https://doi.org/10.1109/jcn.2018.000065

Abstract:
Presents the aim and scope of this publication. Also includes information for authors.
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