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(searched for: (10.5155/eurjchem.4.2.92-97.615))
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Mohamed Sayed Behalo, Sciprofile linkAshraf A. Aly, Ashraf Farouk Wasfy, Marwa Mohamed Rizk
European Journal of Chemistry, Volume 4, pp 92-97; doi:10.5155/eurjchem.4.2.92-97.615

Abstract:
An efficient synthesis of 1,2,4-triazole derivatives, fused to five and six membered rings from 4-amino-5-[(quinolin-8-yloxy)methyl]-4H-1,2,4-triazole-3-thiole (2) was described. The structural formula of all derivatives was confirmed and characterized by elemental analysis and spectral studies. Some of the synthesized compounds were also investigated for their antibacterial and antifungal activities and compared with standard drugs. Most of the tested compounds demonstrated potent to weak antimicrobial activities.
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