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(searched for: (10.5155/eurjchem.2.3.331-336.319))
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Mervat Mostafa El-Enany, Mona Monir Kamel, Omneya Mahmoud Khalil, Hala Bakr El-Nassan
European Journal of Chemistry, Volume 2, pp 331-336; doi:10.5155/eurjchem.2.3.331-336.319

Abstract:
A novel series of pyrazolo[1,5-a]pyrimidine-3-carbonitriles substituted with 7-amino, 7-substituted amino and 5-substituted amino groups was synthesized. Some of the newly synthesized compounds were tested in vitro on human colon tumor cell line (HCT116). Compound 14a displayed the highest activity among the tested compounds with IC50 that equals to 0.0020 μM.
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