(searched for: (10.5155/eurjchem.2.2.272-275.359))
European Journal of Chemistry, Volume 2; doi:10.5155/eurjchem.2.2.272-275.359
An experimentally simple, efficient Michael addition reaction was developed for the synthesis of various 1,8-dioxooctahydroxanthene derivatives with 1,3-cyclohexanedione/5,5-dimethyl 1,3-cyclohexane dione and different aldehydes by using β-cyclodextrin as a catalyst in water. A biomimetic approach was employed and the corresponding products were obtained in good to excellent yields. β-cyclodextrin can be recovered and reused upto four cycles without loss of catalytic activity.