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(searched for: (10.5155/eurjchem.5.4.676-680.1110))
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European Journal of Chemistry, Volume 5; doi:10.5155/eurjchem.5.4.676-680.1110

Abstract:
An efficient and convenient route is described for the synthesis of new pyrazolo [1,5-a] pyrimidine derivatives by the reaction of 4-(4’-chloro-phenylazo)-5-amino pyrazole with α,β-unsaturated carbonyl compounds (chalcones) using polyethylene glycol (PEG-400) as benign reaction medium. The advantage of this protocol includes the excellent yields, operational simplicity, short reaction times and avoidance of volatile organic solvents and expensive catalysts.
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